• 동국한의학연구소논문집
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• 제6권2호
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• pp.135-143
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• 1998

산업 발달과 더불어 경제가 발전하고 있으나, 그것에 따른 매연의 증가로 인해 호흡기 질환으로 고생하고 있는 환자가 날로 늘어나고 있는 실정으로 임상에서 특히 많이 발생되는 만성 호흡기질환 중 호흡기 조직 자체에 손상을 일으킬 수 있는 질환이 많기에, 이에 소자도담강기탕이 인위적으로 호흡기 조직을 손상시킨 것에 대해 얼마나 효과가 있는지 알아보고저 본실험을 하였는 바, 방법은 흰쥐를 대상으로 $SO_2$를 흡인시킨 후 5일간, 그리고 $SO_2$ 흡입 전 10일과, 흡입 후 5일간 연속으로 소자도담강기탕을 경구투여하여 기관상피 및 전액분비세포를 관찰하여 유의한 효과를 얻었기에 보고하는 바이다.

• Journal of Oral Medicine and Pain
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• 제20권1호
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• pp.53-65
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• 1995

The growth and synthetic activities of fibroblasts are regulated by cytokines and growth factors derived from activated inflammatory cells. Stimulatory effect of low level laser (LLL) radiation on wound healing seems to be in part due to direct stimulatory action on cell proliferation and synthetic activities of fibroblasts. Also indirect stimulatory effect on the fibroblast function through inflammatory or immune cells is another possible mechanism of biostimulatory action of LLL. This study was performed to determine the growth rate of human gingival fibroblasts obtained biopsy and culture, fibroblast cell line, and immune cell line by using $[^3H]-$ thymidine incorporation test. And gene expression pattern was also analyzed by using the DNA probe such as Hsp70, IL-1$\beta$, MIP-1$\alpha$ and actin cDNA. Proliferation rate of gingival fibroblast was increased by LLL irradiation, but no more effect was added by LPS or IL-1$\beta$ pretreatment Enhanced Hsp70 gene expression was found from gingival fibroblasts and fibroblast cell line COS by LLL irradiation., which was not more increased by LPS or IL-1$\beta$ pretreatment. LLL-irradiated promyelcytic cell line HL-60 and macrophage cell line RAW264.7 showed significant stimulatory effect of proliferation rate when compared with respective control. However there were no changes in growth rate of other immune cell tested in this study, such as B cell line WR19n.l and 230, helper T cell line Jurkat and Hut78, cytolytic T cell line CTLL-r8. By LLL-irradiation Hsp70 gene expression was increased in RAW246.7 and HL-60, not in CTLL-R8. And IL-1$\beta$ and MIP-1$\alpha$ gene expression were induced only from LLL-irradiated RAW264.7. These results led us to presume that LLL radiation may affect to the immune cells, especially to macrophage, through which it might promote wound healing process.

• 말소리와 음성과학
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• 제7권1호
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• pp.27-37
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• 2015

This study was mainly aimed at investigating on the effects of background noises (i.e., white noise, multi-speaker conversational babble) on stuttering rate and other speech-related measures (i.e., articulation rate, speech effort). Nine Korean-speaking adults who stutter participated in the study. Each of the participants was asked to read a series of passages under each of four experimental conditions (i.e., typical solo reading (TR), choral reading (CR), reading under white noise presented (WR), reading with multi-speaker conversational babble presented (BR). Stuttering rate was computed based on a percentage of syllables stuttered (%SS) and articulation rate was also assessed as another speech-related measure under each of the experimental conditions. To examine the amount of physical effort needed to read, the speech effort was measured by using the 9-point Speech Effort Self Rating Scale originally employed by Ingham et al. (2006). Study results showed that there were no significant differences among each of the passage reading conditions in terms of stuttering rate, articulation rate, and speech effort. In conclusion, it can be argued that the two different types of background noises (i.e., white noise and multi-speaker conversational babble) are not different in the extent to which each of them enhances fluency of adults who stutter. Self ratings of speech effort may be also useful in measuring speech-related variables associated with vocal changes induced under each of the fluency enhancing conditions.

• 생약학회지
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• 제37권3호
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• pp.190-195
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• 2006

Obesity is associated with a number of pathological disorders such as non-insulin-dependent diabetes, hypertension, hyperlipidemia, and cardiovascular diseases. Bangpoongtongsungsankamibang (BTSK) has been widely used in the oriental medicine for the treatment of several diseases associated with inflammatory abnormalities in cardiovascular and nervous system. The BTSK is the modified prescription of Bangpoongtongsungsankamibang in which sea tangle (Laminaria japonica) were added. This study was carried out to detemine the anti-obestic effects of BTSK. Pretreatment with the BTSK at daily dose of 100 or 200 mg/kg (p.o.) far 4 weeks reduced serum triglyceride, total cholesterol contents in rat induced by Poloxamer-407 or Triton WR-1339, respectively. Furthermore, post-treatment with BTSK far four weeks also inhibited body weight gain, adipose tissue mass and hyperlipidemia induced by the high fat diet for six weeks. The BTSK shifted serum total-, HDL- and LDL-cholesterol levels toward the values of normal group, suggesting that BTSK has hypolipldemlc effects. The rats fed BTSK reduced lipid peroxide and hydroxy radical in the rat blood and increased superoxide dismutase (SOD) activity compared to the control group. Taken together, these results superoxide that BTSK improve hyperlidemia and obesity via the upregulation of anti-oxidative mechanism.

• 해양환경안전학회:학술대회논문집
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• 해양환경안전학회 2007년도 추계학술발표회
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• pp.211-214
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• 2007

본 논문에서는 800MHz대역의 TRS(Trunked Radio System)대역을 비롯한, GSM(Global System for Mobile telecommunication), CDMA(Code Division Multiple Access) 대역을 통합할 수 있는 광대역 마이크로스트립 안테나를 설계하고자 한다. 그리고 선박 및 해상 안전에 상용 가능한 선박 기지국 중계기용 안테나를 설계하였다. 마이크로 스트립 안테나의 협대역을 개선하기 위해서 직사각형 패치에 U자 형태의 급전구조를 갖고, 그라운드와 급전 사이에 유전체(${\varepsilon}_T$ = 2.1), 패치와 급전 사이에는 유전체 (${\varepsilon}_T$ = 1)인 서로 다른 유전체를 사용하여 이중 공진 효과를 이용하였다. 설계된 안테나의 주파수 대역폭(VSWR 2:1)은 $780MHz{\sim}1.83GHz$로 2.61GHz의 광대역 특성을 보였으며. 또한 E-평면과 H-평면 모두 이득은 9.dBi이상. 3dB 빔폭은 E-평면 과 H-평면 $60^{\circ}$이상의 개선된 특성을 보였다.

• Fisheries and Aquatic Sciences
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• 제22권11호
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• pp.27.1-27.6
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• 2019

Background: In order to assess the high value-added use of the alginate-free residue of sea tangle, an animal study was performed to evaluate the functional activities and key compounds present. In the animal study, sea tangle and the alginate-free residue demonstrated good anti-hyperlipidemic and anti-arteriosclerotic abilities. Results: The functional compounds in the alginate-free residue of the sea tangle were effectively extracted by supercritical fluid extraction (SFE). The optimum extraction temperature and pressure were 40 ℃ and 6500 psi (M1) in the SFE, a better method in comparison to the conditions of 70 ℃ and 4500 psi (M2), respectively. The anti-atherosclerotic effects of the alginate-free residue of sea tangle (M1, M2) were investigated in Sprague-Dawley rats treated with poloxamer 407, Triton WR 1339, corn oil, and a high-fat diet. The M1 fraction reduced the serum lipid levels with greater efficacy than the M2 fraction. In the hyperlipidemic rats, treatment with M1 decreased the serum triglyceride (TG), total cholesterol (TC), and low-density lipoprotein-cholesterol (LDL-C) levels when compared to the levels in normal rats. Conclusion: Our results demonstrated that the alginate-free residue of sea tangle reduces serum TC, TG, and LDL-C. These results suggest that the alginate-free residue of sea tangle contains physiologically active components, such as fucosterol, that may exert beneficial effects in the prevention of atherosclerosis.

• 한국연초학회지
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• 제11권2호
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• pp.157-179
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• 1989

This Study was conducted to estimate the degree of dominance and gene frequency of some sueful characters in tobacco. The eight parents and a set of 28 crosses of F'1s was F'2s were used as materials, and planted on oriental's and burley cultivated system as randomized block designs, respectively. The observed characters were six agronomic characters which were plant height, number of leaves per plant, leaf length, leaf width, days to flowering and yield, and the data obtained from the experiment were analyzed from methods by Hayman's and Jinks. The results obtained are summarized as follows: 1. In Vr-Wr graphical analysis, number of leaves per plant, leaf length, days to flowering and yield were found to be inherited in partial dominance, and plant height was over dominance to be similar to complete dominance, but leaf width was inherited with partial dominance close to complete dominance. 2. In the gene frequency, two varieties Xanthi-Basma and KA 102, for days to flowering and yield had larger number of dominant genes as those were situated near the point of origen. 3. Additive effects of genes(D) were greater than dominance effects of Genes(H) for six agronomic characters except plant height, and mean degree of dominance over all loci was lower than 1 for days to flowering yield, leaf length and number of leaves per plant.

• 한국작물학회지
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• 제23권2호
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• pp.46-53
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• 1978

육도의 출수기의 유전에 관한 정보를 얻고자 5개의 육도품종과 수도품종 통일을 전조합 이면교배하여 출수기를 조사하고 분석하였던 바 그 결과를 요약하면 다음과 같다. 1. 동기온실에서는 F$_1$의 출수기는 모두 양친의 평균보다 단축되었던 바 출수기가 빠른 쪽이 우성이었고 우성의 정도는 부분우성을 나타내었으며 비대입 유전자간의 교호작용은 인정되지 않았다. 2. 하기포장에서는 교배조합에 따라 F$_1$의 출수기가 우친의 평균보다 단축되거나 혹은 지연되었는데 평균 우성의 방향은 출수기가 늦어지는 쪽이었으며 우성의 정도는 회귀선이 원점위를 통과하여 부분우성을 나타내고 었었다. 3. 하기포장의 경우 Wr, Vr간의 회귀는 유의성이 인정되지 않았고 Unit slope과도 멀어 비대립유전자간의 교호작용이 인정되었는데 평화나 와 삼낭에 교호작용을 유발하는 인자자리가 있는 것으로 추측된다. 4. 동기온실의 경우 평화나 및 청국대왕은 우성대에 포천장망벼와 농림나 001는 열성대에 위치하였는데 하기국장에서는 삼낭과 청국대왕은 우성대에 그리고 통일과 농림나 001는 열성대에 위치하고 있었다.

• 한국광학회지
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• 제12권4호
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• pp.270-275
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• 2001

본논문에서는 구면수차가 포함된 광학 디스크 시스템에 환형 위상변조 apodizer를 적용하여 bump 형태에 따른 재생신호를 스칼라 회절 이론을 이용하여 조사하였다. 이때 구면수차의 영향을 최소로 하는 최적변수를 결정하기 위해 동(pupil)의 반경 r에 대한 파면수차량에 절대값을 취해서 얻는 최대치와 임의의 값의 비로 W$_{R}$을 정의하였으며 원추형과 준원추형 그리고 원추형 bump로 다양한 형태의 bump를 고려하였다. 환형 위상변조 apodizer는 bump 반경과 형태의 변화에 따른 재생신호가 균일한 진폭과 유사한 경향을 나타냈으며 항상높은 최대재생신호를 가졌다. 구면수차의 증가에 따른 최대재생신호의 변화는 아주 작았으며 실제 광학 디시크 시스템에 사용 가능한 0.6 이상의 재생신호를 갖는 신호 bump 반경의 변화가 거의 없었다. 특히 $W_R$ 이 0.4와 0.6인 경우에는 구면수차에 대한 보정효과가 가장 큼을 알 수 있었다.

• 한국축산식품학회지
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• 제40권5호
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• pp.813-830
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• 2020

In this study, the potential of infrared assisted freeze-drying (IRAFD) was tested for the production of shelf-stable edible insects: Protaetia brevitarsis larva (larva of white-spotted flower chafer). The IRAFD system was customized using an infrared lamp, K-type thermocouple, controller, and data acquisition system. The infrared lamp provided the sublimation energy for rapid freeze-drying (FD). The IRAFD conditions were continuous IRAFD-5.0 kW/㎡ and IRAFD-5.0 kW/㎡ at different weight reduction (WR) (10%, 20%, and 30%). The continuous IRAFD reduced the drying time to 247 min compared to the 2,833 min duration of FD (p<0.05). The electrical energy could be reduced by more than 90% through infrared radiation during FD (p<0.05). The Page model resulted in the best prediction among the tested drying kinetic models. In terms of quality, IRAFD showed significantly lower hardness, chewiness, and higher protein levels than hot air drying and FD (p<0.05). IRAFD better preserved the glutamic acid (6.30-7.29 g/100 g) and proline (3.84-5.54 g/100 g). The external product appearance after IRAFD exhibited more air pockets and volume expansion, which might result in a good consumer appeal. In conclusion, this study reports the potential of IRAFD in producing shelf-stable and value-added edible insects.