• International Journal of Aeronautical and Space Sciences
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• 제13권1호
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• pp.14-26
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• 2012

The only extraterrestrial life detection experiments ever conducted were the three which were components of the 1976 Viking Mission to Mars. Of these, only the Labeled Release experiment obtained a clearly positive response. In this experiment $^{14}C$ radiolabeled nutrient was added to the Mars soil samples. Active soils exhibited rapid, substantial gas release. The gas was probably $CO_2$ and, possibly, other radiocarbon-containing gases. We have applied complexity analysis to the Viking LR data. Measures of mathematical complexity permit deep analysis of data structure along continua including signal vs. noise, entropy vs.negentropy, periodicity vs. aperiodicity, order vs. disorder etc. We have employed seven complexity variables, all derived from LR data, to show that Viking LR active responses can be distinguished from controls via cluster analysis and other multivariate techniques. Furthermore, Martian LR active response data cluster with known biological time series while the control data cluster with purely physical measures. We conclude that the complexity pattern seen in active experiments strongly suggests biology while the different pattern in the control responses is more likely to be non-biological. Control responses that exhibit relatively low initial order rapidly devolve into near-random noise, while the active experiments exhibit higher initial order which decays only slowly. This suggests a robust biological response. These analyses support the interpretation that the Viking LR experiment did detect extant microbial life on Mars.

• Asian Pacific Journal of Cancer Prevention
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• 제15권9호
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• pp.3973-3980
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• 2014

Prostate adenocarcinoma is one of the leading causes of cancer related mortality in men but still limited knowledge is available about its associated functional SNPs including rs1042522 (Pro72Arg). The present study was undertaken to explore the association of this SNP with susceptibility to prostate adenocarcinoma along with its structural and functional impacts in the Pakistani population in a case-control study. Three-dimensional structure of human TP53 with Pro72Arg polymorphism was predicted through homology modeling, refined and validated for detailed structure-based assessment. We also carried out a HuGE review of the previous available data for this polymorphism. Different genetic models were used to evaluate the genotypes association with the increased risk of PCa (Allelic contrast: OR=0.0.34, 95%CI 0.24-0.50, p=0.000; GG vs CC: OR=0.17, 95%CI 0.08-0.38, p=0.000; Homozygous: OR=0.08, 95%CI 0.04-0.15, p=0.000; GC vs CC: OR=2.14, 95%CI 1.01-4.51, p=0.046; Recessive model: OR=0.10, 95%CI 0.05-0.18, p=0.000; Log Additive: OR=3.54, 95%CI 2.13-5.89, p=0.000) except the Dominant model (OR=0.77, 95%CI 0.39-1.52, p=0.46). Structure and functional analysis revealed that the SNP in the proline rich domain is responsible for interaction with HRMT1L2 and WWOX. In conclusion, it was observed that the Arg coding G allele is highly associated with increased risk of prostate adenocarcinoma in the Pakistani population (p=0.000).

• Clinical and Experimental Reproductive Medicine
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• 제42권3호
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• pp.101-105
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• 2015

Objective: Several publications have established a relationship between sperm DNA damage and male factor infertility, based on data from America, Europe, and Asia. This study aimed to compare the extent of sperm DNA damage in sperm samples from Nigerian men with unexplained infertility and in sperm samples from a fertile group composed of sperm donors who had successfully impregnated a female partner naturally or through assisted conception. Methods: A total of 404 men underwent male fertility evaluation at Androcare Laboratories and Cryobank participated in this study. Semen analysis and a sperm chromatin structure assay (SCSA) were performed on all subjects. Results: The men in the unexplained infertility group were slightly older than the men in the fertile sperm group ($36{\pm}10$ years vs. $32{\pm}6$ years, p=0.051). No significant difference was observed between the two groups in semen analysis parameters ($p{\geq}0.05$). Men in the unexplained infertility group with normal semen parameters had a significantly higher DNA fragmentation index (DFI) than men in the fertile sperm group ($27.5%{\pm}7.0%$ vs. $14.1%{\pm}5.3%$, p<0.05). In the unexplained infertility group, 63% of the men had a DFI greater than 20%, compared to 4% in the fertile sperm group. In the unexplained infertility group, 15.2% of the subjects had a DFI greater than 30%, compared to 1% in the fertile sperm group. Conclusion: Our study showed that the SCSA may be a more reliable predictor of fertility potential than traditional semen analysis in cases of unexplained infertility.

• 대한수의학회지
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• 제36권1호
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• pp.235-245
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• 1996

Serial ultrasonographic examinations were performed on 9 pregnant Korea Jin-do bitches that were the Korean native breed, from days 15 to 60 pregnancy to determine the time of first detection and ultrasonographic appearance of the fetal and extra-fetal structures of pregnancy. Gestational age was timed from the day of ovulation (Day 0), which was estimated to occur when plasma progesterone concentration was first increased above 4.0 ng/ml. Gestational ages at earliest detection of the following fetal and extra-fetal structures were; gestational sac at days 17 to 22; placental layers in the uterine wall at days 20 to 24; zonary placenta at days 25 to 28; yolk sac membrane at days 22 to 24; amnionic membrane at days 27 to 29; embryo initial detection at days 21 to 23; fetal heartbeat at days 21 m 25; bipolar shape embryo at days 25 to 26; fetal movement at days 28 to 31; limb buds at days 31 to 35; anechoic area in head at days 31 to 36; stomach at days 34 to 37; urinary bladder at days 34 to 37; skeleton at days 36 to 38; dorsal sagittal tubular structure in vertebrae at days 36 to 38; lung hyperechoic vs liver at days 37 to 39; liver hypoechoic vs abdomen at days 37 to 40 and kidney at days 43 to 48, respectively.

• 대한금속재료학회지
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• 제56권12호
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• pp.845-853
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• 2018

To understand the effect of microstructural factors (i.e., the size of ${\alpha}$ phase, equiaxed vs bimodal structure) on high cycle fatigue (HCF) and fatigue crack propagation (FCP) behaviors of mill-annealed Ti-6Al-4V (Ti64) alloy, three specimens of EQ (equiaxed)-8 (8 indicates the size of ${\alpha}$ grain), BM (bimodal)-8, and BM-16 were studied. The uniaxial HCF and FCP tests were conducted at an R ratio of 0.1 under sinusoidal fatigue loading. The microstructural influence (i.e., EQ vs BM) was not significant on the tensile properties of mill-annealed Ti64 alloy, and showed an increase in tensile strength and elongation with decreasing gauge thickness from 50 mm to 1.3 mm. The microstructure, on the other hand, affected the resistance to HCF substantially. It was found that the EQ structure in mill-annealed Ti64 has better resistance to HCF than the BM structure, as a result of different crack initiation mechanism. Unlike HCF behavior, the effect of microstructural features on the FCP behavior of mill-annealed Ti64 was not significant. Among the three specimens, BM-16 specimen showed the highest near-threshold ΔK value, probably because it had the greatest slip reversibility with large ${\alpha}$ grains. The effect of microstructural factors on the HCF and FCP behaviors of mill-annealed Ti64 alloy are discussed based on fractographic and micrographic observations.

• 재무관리연구
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• 제4권1호
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• pp.45-58
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• 1988

This paper is to examine the relevance of banarptcy Costs (BC) to Capital Structure with three related purposes: whether or not BC are trival,, a proxy methodology for estimating BC, the present value of expected BC vs tax benefits' trade off. For these purposes, the samples includes 19 industrial firms which went bankrupt over period 1970-78 and secondly seven large Companies which went bankrnpt recently in the U.S. The results are quite strong that BC are not trival. In many cases they exceed 20% of the value of the firm measured just prior to bankruptcy. Direct BC are explicit and administrative costs paid by debtor in reorganization/liqaidation process. Indirect BC are essentially defined as unexpected losses and estimated in two way: a regression method and security analyst's forcasts. The present value of expected BC for many of the bankrupt firm is found to exceed the present value of tax benefits from leverage. This implies that firms were overleveraged and that a potentially important ingredient in the discussion of optimum capital structure is indeed the BC factor. Therefore, BC are relevant to the cost of capital structure decision and should he considered seriously.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 추계학술대회 논문집 전기물성,응용부문
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• pp.201-203
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• 2005

To improvement the performance of PDPs, we developed an ac-PDP with new fence structure. By measuring minimum sustaining voltage(Vs), discharge current(Ion), discharge(Ioff), and brightness of the light from a 4-inch at-PDP, performances of the conventional structure and proposed structure are compared. The experimental results show that the test panel with the proposed new fence structure shows high luminance by 10%, and high luminous efficiency by 30% compared with the conventional structure at the Ne-Xe(8%) gas mixture of 400 torr.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 C
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• pp.2169-2171
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• 2005

A new structure is proposed to achieve a low sustaining voltage and high luminous efficacy. By measuring minimum sustaining voltage(Vs) discharge current(Ion), discharge(Ioff), and brightness of the light from a 4-inch ac-PDP, performances of the conventional structure and proposed structure are compared. When compared with the conventional structure, proposed structure showed 6.5% Vsm improvement, 22% luminance improvement and 20% light dispersion improvement at the Ne-Xe(8%) gas mixture of 400 torr.

• 한국어류학회지
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• 제32권2호
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• pp.49-54
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• 2020

한국 고유종 남방종개 Iksookimia hugowolfeldi 후각기관의 형태 및 형태계측학적 특징을 확인하기 위해 실체 현미경을 이용하여 관찰하고 통계프로그램 SPSS로 분석하였다. 후각 기관의 외부 형태는 주둥이 좌우로 돌출된 튜브형의 전비공(직경 0.35~0.53 mm)과 눈모양의 후비공(장축 0.32~0.68 mm)으로 구성된다. 후각기관 내부에서는 14~21개의 후판으로 구성된 로제트 구조가 확인된다. 형태계측학적 분석에서 후판개수(수컷 vs. 암컷, 18±1.8 vs. 17±1.6)와 체장대비 후판개수 비율(24.2±1.3% vs. 21.7±2.5%)은 수컷이 암컷보다 더 높은 값을 나타냈다. 체장과 후판은 수컷에서 유의미한 상관관계(P<0.001)를 나타냈다. 이와 같은 남방종개의 후각기관 특징은 서식처 바닥의 모래를 파고 숨는 저서성 생활의 적응과 암수 간 생식에서의 후각의존성 차이를 반영하는 결과로 사료된다.

• 한국산림과학회지
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• 제96권5호
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• pp.520-527
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• 2007

Biomass and species diversity of understory vegetation after fertilization were studied for 28-year-old Quercus acutissima plantation (MQA), 29-year-old Pinus densiflora plantation (MPD), 8-year-old Betula platyphylla var. japonica plantation after coal reclamation (YBP), and 4-year-old Pinus densiflora plantation after forest fire (YPD) in central Korea. Nitrogen + phosphorus + potassium (6:4:1) fertilizer was applied for 3 years from 2004. Thereafter photosynthetically active radiation (PAR) and understory species richness and diversity were measured in late July-early August 2006. PAR (${\mu}mol\;m^{-2}S^{-1}$) was higher at the fertilization treatment (100.9) than at the control (67.0) for MQA while was lower at the fertilization treatment (156.5) than at the control (268.7) for MPD. Total understory biomass (t $ha^{-1}$) was lower at the fertilization plot (1.8) than at the control plot (3.0) for YPD, however, there were no differences in biomass between fertilization and control plots for MQA, MPD and YBP. Total species number of understory vegetation was higher for fertilization than for control at MPD (47 vs. 45) and YPD (21 vs. 13), and was higher for mature plantations (33 vs. 37 for MQA and 47 vs. 45 for MPD) than for young plantations (16 vs. 16 for YBP and 21 vs. 13 for YPD). Species richness and diversity were higher at the fertilization treatment than at the control for MQA, YBP, and YPD while were lower at the fertilization treatment than at the control for MPD, however, the differences were not statistically significant. Our results indicate that there were no consistent patterns in light conditions, biomass and species richness and diversity of understory vegetation following fertilization. More detailed long-term studies with different fertilizer applications would be necessary to conclude the influence of fertilization on understory vegetation in the region.