• Title/Summary/Keyword: Volume of distribution

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Dosimetric Validation of the Acuros XB Advanced Dose Calculation Algorithm for Volumetric Modulated Arc Therapy Plans

  • Park, So-Yeon;Park, Jong Min;Choi, Chang Heon;Chun, Minsoo;Kim, Jung-in
    • Progress in Medical Physics
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    • v.27 no.4
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    • pp.180-188
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    • 2016
  • Acuros XB advanced dose calculation algorithm (AXB, Varian Medical Systems, Palo Alto, CA) has been released recently and provided the advantages of speed and accuracy for dose calculation. For clinical use, it is important to investigate the dosimetric performance of AXB compared to the calculation algorithm of the previous version, Anisotropic Analytical Algorithm (AAA, Varian Medical Systems, Palo Alto, CA). Ten volumetric modulated arc therapy (VMAT) plans for each of the following cases were included: head and neck (H&N), prostate, spine, and lung. The spine and lung cases were treated with stereotactic body radiation therapy (SBRT) technique. For all cases, the dose distributions were calculated using AAA and two dose reporting modes in AXB (dose-to-water, $AXB_w$, and dose-to-medium, $AXB_m$) with same plan parameters. For dosimetric evaluation, the dose-volumetric parameters were calculated for each planning target volume (PTV) and interested normal organs. The differences between AAA and AXB were statistically calculated with paired t-test. As a general trend, $AXB_w$ and $AXB_m$ showed dose underestimation as compared with AAA, which did not exceed within -3.5% and -4.5%, respectively. The maximum dose of PTV calculated by $AXB_w$ and $AXB_m$ was tended to be overestimated with the relative dose difference ranged from 1.6% to 4.6% for all cases. The absolute mean values of the relative dose differences were $1.1{\pm}1.2%$ and $2.0{\pm}1.2%$ when comparing between AAA and $AXB_w$, and AAA and $AXB_m$, respectively. For almost dose-volumetric parameters of PTV, the relative dose differences are statistically significant while there are no statistical significance for normal tissues. Both $AXB_w$ and $AXB_m$ was tended to underestimate dose for PTV and normal tissues compared to AAA. For analyzing two dose reporting modes in AXB, the dose distribution calculated by $AXB_w$ was similar to those of AAA when comparing the dose distributions between AAA and $AXB_m$.

Salinity Distribution in the Mid-eastern Yellow Sea during the High Discharge from the Keum River Weir (금강하구언 대량방류시 황해 중동부 해역의 염분분포)

  • Choi, Hyun-Yong;Lee, Sang-Ho;You, Kwang-Woo
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.4 no.1
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    • pp.1-9
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    • 1999
  • Hydrographic survey was carried out in the mid-eastern Yellow Sea from Keum River to Taean Peninsula in order to study the motion of the freshwater from the Keum River during July 07-12, 1997 when a large volume of freshwater was discharged from the Keum River weir. The low-salinity (less than 30.0 psu) plume was distributed over the large area between the Keum River and Ochong Island, 60 km northwest off the Keum River mouth. A band of relatively low saline water, originating from the Keum River, was also observed to the north of Ochong Island. The strong haline front had advanced from near Sibidongpa Island to Ochong Island, 25 km northwest of Sibidongpa Island, for 48 hours. A northwestward flow of a speed greater than 0.2 m/s was observed in the surface plume layer to the north of Sibidongpa Island where the water column was strongly stratified. The observed mean flow and the change of the frontal position are interpreted as resulting from the spreading of the Keum River plume. These results suggest that the discharge from the Keum River plays an important role in the coastal circulation of the mid-eastern Yellow Sea adjacent to the river.

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Characterization and Preparation of Al-Pillared Clay (Aluminium-Pillared Clay의 제조 및 특성)

  • Park, Se-Jun;Ha, Baik-Hyon;Jeong, Soon-Yong;Suh, Jeong-Kwon;Lee, Jung-Min
    • Applied Chemistry for Engineering
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    • v.10 no.2
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    • pp.304-309
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    • 1999
  • Aluminum-pillared clay was prepared by the intercalation of Al-hydroxy oligomer into domestic bentonite. The solid products are characterized by XRD, nitrogen adsorption/desorption, EDX, and SEM. The solid products show relatively high specific surface areas in the range of $104{\sim}228m^2/g$, and their specific surface area, micropore surface area, and micropore volume increase with increasing the mole ratio of OH/Al. From the results of pore size distribution calculated by BJH equation, it was found that aluminum-pillared clay also contains much mesopore near $40{\AA}$. These results indicate that Al-hydroxy oligomer was intercalated into bentonite, and aluminum oxide was pillared among the layers of bentonite, and micropore and mesopore was finally developed into layers. As OH/Al mole ratio increases, the thermal stability of aluminum-pillared clay increases. This result can be explained by the fact that the density of layers is increased due to the formation of aluminum pillars.

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Analysis of Temporal and Spatial Distribution of Traffic Accidents in Jinju (진주시 교통사고의 시계열적 공간분포특성 분석)

  • Sung, Byeong Jun;Bae, Gyu Han;Yoo, Hwan Hee
    • Journal of Korean Society for Geospatial Information Science
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    • v.23 no.2
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    • pp.3-9
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    • 2015
  • Since changes in land use in urban space cause traffic volume and it is closely related to traffic accidents. Therefore, an analysis on the causes of traffic accidents is judged to be an essential factor to establish the measure to reduce traffic accidents. In this regard, the analysis was conducted on the clustering by using the nearest neighbor indexes with regard to the occurrence frequencies of commercial and residential zone based on traffic accident data of the past five years (2009-2013) with the target of local small-medium sized city, Jinju-si. The analysis results, obtained in this study, are as follows: the occurrence frequency of traffic accidents was the highest in spring and the lowest in winter respectively. The clustering of traffic accident occurrence at nighttime was stronger than at daytime. In addition, terms of the analysis on the clustering of traffic accident according to land use, changes according to the seasons was not significant in commercial areas, while clustering density in winter tended to become significantly lower in residential areas. The analysis results of traffic accident types showed that the side-right angle collision of cars was the highest in frequency occurrence, and widespread in both commercial areas and residential areas. These results can provide us with important information to identify the occurrence pattern of traffic accidents in the structure of urban space, and it is expected that they will be appropriately utilized to establish measures to reduce traffic accidents.

Separation and Elution Behavior of Some Iron(Ⅲ)porphyrin Complexes by Reversed-Phase Liquid Chromatography (역상 액체 크로마토그래피에 의한 Iron(Ⅲ)porphyrin 착화합물들의 분리 및 용리거동에 관한 연구)

  • Chang Hee Kang;In Whan Kim;Won Lee
    • Journal of the Korean Chemical Society
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    • v.37 no.12
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    • pp.1035-1046
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    • 1993
  • Some iron(III)porphyrin complexes were prepared, and identified by the spectroscopic methods. Elution behavior of iron(III)porphyrin complexes was investigated by reversed-phase HPLC. The optimum conditions for the separation of iron(III)porphyrin complexes were examined with respect to flow rate and mobile phase strength. These complexes were successfully separated on NOVA-PAK $C_{18}$ column using methanol / water(95/5) for $[T_pCF_3PP)Fe(R)]$ and methanol / water (98/2) for $[(P)Fe(C_6F_5)]$ as a mobile phase. It was found that these complexes were largely eluted in an acceptable range of capacity factor value ($0{\leq}logk'{\leq}1$). The dependence of the capacity factor (k') on the volume fraction of water in the binary mobile phase as well as the dependence of k' on the liquid-liquid extraction distribution ratio$(D_c)$ in methanol-water / n-pentadecane extraction system showed a good linearity. It means that the retention of iron(III)porphyrin complexes on NOVA-PAK $C_{18}$ column is largely due to the solvophobic effect. Also, there was a good linear dependence of the capacity factor(k') on the column temperature and enthalpy calculated by van't Hoff plot. From these results, it was confirmed that the retention mechanism of iron(III)porphyrin complexes in reversed-phase liquid chromatography was invariant under the condition of various temperature, and the solvophobic binding process exhibited isoequilibrium behavior.

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A Study on the Elution Behavior of Pd-Isonitroso ethylacetoacetate imine Chelates by Reversed-phase High Performance Liquid Chromatography (역상 고성능 액체 크로마토 그래피에 의한 Pd(II) - isonitrosoethylacetoacetate imine 유도체 킬레이트의 용리거동에 관한 연구)

  • Kim, Hyun
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.19 no.1
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    • pp.20-30
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    • 1993
  • Liquid Chromatographic behavior of Pd(II) in Isonitosoethylacetoacetate imine IEAA-NR: R=H, CH3, C2H5, n-C3H7, n-C4H9, C6H5-CH2) Chelates were investigated by reversed phase high performance 1iquid chromatography on Micropak MCH-5 Column using Methanol /water as mobile phase. The optimum condition for the separation of Pd-Isonitrosoethylacetoacetate imine chelates were examined with respect to the flow rate, mobile phase strength. It was found that Pd(IEAA-NR)2 chelates were eluted in an acceptable range of the capacity factor value (0 $\leq$ log k' $\leq$ 1), The dependence of the logarithm of capacity factor(k') on the volume fraction of water in mixture with in the binary mobile phase was examined. Also, the dependence of k'on the liquid-liquid extraction distribution constant in methanol-water / n-alkane extraction system was on system was invert tigated for Pd(IEAA-NR)2. Both kinds of dependence are linear, which suggests that the retention of the electroneutral metal chelates be largely due to the solvophobic effect.

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Application of CFD Program for Analyzing the Hydrodynamic Characteristics of Baffled PAC Contactor (격벽식 분말활성탄 접촉조의 흐름해석을 위한 전산유체역학 프로그램의 적용)

  • Ahn, Chang-Jin;Ahn, Sang-Jin
    • Journal of Korea Water Resources Association
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    • v.35 no.2
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    • pp.221-229
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    • 2002
  • For the efficient design of baffled Powdered activated carbon(PAC) contractor, which has been widely used in water treatment plant(WTP) against the algae-related odor problems, a CFD(computational fluid dynamics) program was applied. In order to verify the performance of FLOW-3D program, the previously reported results of tracer tests from a pilot-scale PAC contractor(working volume of 288 liters) were compared to those from FLOW 3D. The results of FLOW-3D simulation were very similar to those from tracer tests conducted with the Pilot-scale PAC contactor. On the other hand, the hydrodynamic characteristics of baffled contractor in the P-WTP were simulated by using FLOW-3D. Simulation results on the distribution of PAC particles showed that there are some stagnant parts in the back side of baffles in which PAC Particles are not present. These stagnant parts might decrease the adsorption capacity of PAC particles. When the baffles were changed to maze-type intra-basin baffling, PAC particles were evenly distributed and the amount of stagnant parts reduced. In conclusion, it is anticipated that FLOW-3D simulation could be a viab1e tool for analyzing the hydrodynamic characteristics of structures used in drinking water treatment plant.

Clinical Evaluation of Dose Distribution in High Dose Rate Intracavitary Irradiation in the Treatment of Cervical Cancer (고선량 강내 조사법을 이용한 자궁 경부암의 방사선 치료 계획에 대한 임상적 고찰)

  • Shin, Sei-One;Kim, Myung-Se
    • Journal of Yeungnam Medical Science
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    • v.6 no.1
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    • pp.87-98
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    • 1989
  • Clinical estimation of bladder and rectal doses from high dose rate intracavitary irradiation in carcinoma of the cervix uteri has been initiated on a routine basis in an effort to obtain the optimum radiotherapeutic dose. Simulation films with contrast media are used to image the bladder and rectum, and dose rates are estimated at various interesting points with the aid of treatment planning computer, NEC Therac-2300. Fifty-three patients have been reviewed in order to ascertain the correlation between radiation dose at interesting points in the bladder and rectum and the dose at Point A and B. The dose ratio between doses at Point A 'and interesting points is an important clinical factor in evaluating the treatment planning. This also serves as documentation of the dose to normal structures within the treatment volume. Authors conclude that obtained data are within acceptable ranges and routine simulation films of the bladder and rectum after administration of contrast media with dose calculations at interesting points provide important information for optimizing radiotherapy planning in the treatment of cervical carcinoma without increased time and effort or patient's discomfort.

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Trends and Synchronization of Transaction Amounts by Product group of Online Malls in Online Shopping Malls (온라인쇼핑몰에서 Online몰의 상품군별 거래액 동향과 동조화 현상)

  • Choi, Soo-Ho;Choi, Jeong-Il
    • Journal of Digital Convergence
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    • v.19 no.2
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    • pp.151-160
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    • 2021
  • The purpose of this study is to classify online shopping malls into total transaction amount and transaction amount by product, and compare them to find synchronism. The data used in this study were collected from KOSIS for Food Services, Home Appliances·Electronics·Communication devices, Food & Beverages, House_Goods, Clothing, Computers & Peripheral Devices. The analysis period is a total of 44 monthly data from January 2017 to August 2020. In descriptive statistics, variability is relatively very stable in the case of food service, but is large in the case of clothing. In the correlation analysis, the total transaction amount shows a certain level of correlation with each product. In the analysis of the increase rate, Food Service increased by 1,039%, Home Appliances·Electronics·Communication devices increased by 325%, Food & Beverages increased by 296% and House Goods by 250%, but Clothing decreased slightly to 92.56%. In the Scatter Charts analysis, the distribution of Total transaction amount & House Goods, Total transaction amount & Home Appliances·Electronics·Communication devices is generally upward, showing a high level of synchronization. Due to Corona 19, we will have to continue our efforts to provide speed, stability, convenience and various services in preparation for the increase in transaction volume of online shopping malls.

A Study on Dividing the Feasible Areas to Cut and Calculating the Stumpage Value of Forests using Geographic Information System (지리정보시스템(GIS)을 이용한 벌채가능지역의 구분 및 입목가격 산정에 관한 연구)

  • Kim, Han-Soo;Won, Hyun-Kyu;Choi, Jo-Ryong;Woo, Jong-Choon
    • Journal of the Korean Association of Geographic Information Studies
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    • v.3 no.3
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    • pp.54-68
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    • 2000
  • This study was tried to calculate the stumpage value using GIS technique. Before calculating this price the feasible areas to cut were divided from all forests. The stumpage value per $m^3$ was calculated by the method of calculating back from the market price, according to the working volume of logging unit and clearing a felling area using GIS. The distribution of the stumpage value for the coniferous stands was estimated from minimum 10,000 won to maximum 50,000 won, and for the deciduous stands the stumpage value was distributed from minimum 20,000 won to maximum 40,000 won. The total estimated selling price for the cutting available area (197.3ha) among this study area(250ha) except the cutting limited area was about 1.13 billions won. And the estimated selling price for the korean white pine stands was about 650 millions won, occupied 57% among the total selling price, and for the deciduous stands showed 383 millions won, occupied 34% of the total price, and for the japanese larch was 9.69 millions won, occupied 9% of the total price. But the rigida pine stands showed only 1.22 millions won.

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