• Title/Summary/Keyword: Volume Ratio Coefficient

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Deep Learning-Based Lumen and Vessel Segmentation of Intravascular Ultrasound Images in Coronary Artery Disease

  • Gyu-Jun Jeong;Gaeun Lee;June-Goo Lee;Soo-Jin Kang
    • Korean Circulation Journal
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    • v.54 no.1
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    • pp.30-39
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    • 2024
  • Background and Objectives: Intravascular ultrasound (IVUS) evaluation of coronary artery morphology is based on the lumen and vessel segmentation. This study aimed to develop an automatic segmentation algorithm and validate the performances for measuring quantitative IVUS parameters. Methods: A total of 1,063 patients were randomly assigned, with a ratio of 4:1 to the training and test sets. The independent data set of 111 IVUS pullbacks was obtained to assess the vessel-level performance. The lumen and external elastic membrane (EEM) boundaries were labeled manually in every IVUS frame with a 0.2-mm interval. The Efficient-UNet was utilized for the automatic segmentation of IVUS images. Results: At the frame-level, Efficient-UNet showed a high dice similarity coefficient (DSC, 0.93±0.05) and Jaccard index (JI, 0.87±0.08) for lumen segmentation, and demonstrated a high DSC (0.97±0.03) and JI (0.94±0.04) for EEM segmentation. At the vessel-level, there were close correlations between model-derived vs. experts-measured IVUS parameters; minimal lumen image area (r=0.92), EEM area (r=0.88), lumen volume (r=0.99) and plaque volume (r=0.95). The agreement between model-derived vs. expert-measured minimal lumen area was similarly excellent compared to the experts' agreement. The model-based lumen and EEM segmentation for a 20-mm lesion segment required 13.2 seconds, whereas manual segmentation with a 0.2-mm interval by an expert took 187.5 minutes on average. Conclusions: The deep learning models can accurately and quickly delineate vascular geometry. The artificial intelligence-based methodology may support clinicians' decision-making by real-time application in the catheterization laboratory.

Couette-Poiseuille flow based non-linear flow over a square cylinder near plane wall

  • Bhatt, Rajesh;Maiti, Dilip K.;Alam, Md. Mahbub;Rehman, S.
    • Wind and Structures
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    • v.26 no.5
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    • pp.331-341
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    • 2018
  • A numerical study on the flow over a square cylinder in the vicinity of a wall is conducted for different Couette-Poiseuille-based non-uniform flow with the non-dimensional pressure gradient P varying from 0 to 5. The non-dimensional gap ratio L (=$H^{\ast}/a^{\ast}$) is changed from 0.1 to 2, where $H^{\ast}$ is gap height between the cylinder and wall, and $a^{\ast}$ is the cylinder width. The governing equations are solved numerically through finite volume method based on SIMPLE algorithm on a staggered grid system. Both P and L have a substantial influence on the flow structure, time-mean drag coefficient ${\bar{C}}_D$, fluctuating (rms) lift coefficient ($C_L{^{\prime}}$), and Strouhal number St. The changes in P and L leads to four distinct flow regimes (I, II, III and IV). Following the flow structure change, the ${\bar{C}}_D$, $C_L{^{\prime}}$, and St all vary greatly with the change in L and/or P. The ${\bar{C}}_D$ and $C_L{^{\prime}}$ both grow with increasing P and/or L. The St increases with P for a given L, being less sensitive to L for a smaller P (< 2) and more sensitive to L for a larger P (> 2). A strong relationship is observed between the flow regimes and the values of ${\bar{C}}_D$, $C_L{^{\prime}}$ and St. An increase in P affects the pressure distribution more on the top surface than on bottom surface while an increase in L does the opposite.

A study on the settlement of earth dam by the changes of the density (흙댐의 밀도변화에 의한 압밀침하에 대한 연구)

  • 윤충섭
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.28 no.3
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    • pp.89-98
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    • 1986
  • This study was carried out for the settlement and camber of earth dam by the changes of the density. The testing material was taken five kinds of Soil used as banking material and it was compacted by 100, 95, 90, 85 and 80% compaction degree. The results of the settlement of earth dam whose height ranges from 10m to 50m are as follows. 1.The more the fine particle (n) increases, the higher the liquid limit (WL) and the lower the dry density (rd) becomes as follows; rd=2. 22-0. 0052n (gr/cm$_3$) rd=2. 394-0. 0164WL rd=2. 185-(5. 8n-2. 5WL)X10-$_3$ 2. The higher the optimum moisture content (Wo) becomes, the lower the density becomes as follows; rt,=2. 68-0. 028Wo rd=2. 578-0. 04Wo 3. 3.Most of the consolidation occurs immediately by loading and the more the fine particle increases, the lower the coefficient of consolidation becomes. 4.The more the fine particle increases and lower the compaction degree (D) becomes,the lower the pre-consolidation load (Pc) becomes but on the contrary the compression index (Cc) becomes higher. Those equation is as follows. Pc=3. 32-(4. 3n-3. 0D) X10-2 (kg/cm$^2$) Cc=0. 41+(1. 33n-4. 44D) X10-$^3$ 5.The more the consolidation load (P) increases, the lower the coefficient of volume change (mv) becomes with mv=ap-b, the higher the consolidation ratio (u) becomes with U= (0. 6~1. 35)PO.4 6.The more the fine particle (n) increases, the more the settlement of dam occurs with U=anb and 60-80% of the settlement occurs under construction. 7.The camber of dam has higher value in condition that has more fine particle, poorer compaction and higher height of dam. In the dam construction about twice value of table 7 is required for dam safety.

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Total Body Fat Estimation by Means of Densitometry and Skinfold Thickness in Middle-Aged Men (밀도법 및 피부두겹법에 의한 중년 남자의 총지방량 측정)

  • Nam, Kwang-Hyun;Shin, Dong-Hoon
    • The Korean Journal of Physiology
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    • v.8 no.1
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    • pp.31-37
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    • 1974
  • Formulas for the prediction of total body fat from skinfold thickness in middle aged men were presented. Hydrostatic weighing was made on 35 middle-aged men $(age:\;40{\sim}50\;years)$ sad corrected for residual volume in lung. Skinfold thickness at four sites, namely, arm, back, waist and abdomen were compared with total fat calculated from the formula given by Keys and Brozek and regression equations were derived. In middle-aged men the observed values were: Body density, 1.07478 ; total body fat, 10.51% body weight; lean body mass, 89.49% body weight; arm skinfold thickness, 4.85mm; back, 10.4 ; waist, 7.72; abdomen, 7.62 and mean skinfold thickness of the four sites, 7.59 mm. The correlations between skinfold thickness and body density were high. The correlations between skinfold thickness and total body fat were also high. The coefficient of correlation between total body fat and arm skinfold, mean skinfold thickness were r=0.839 and r=0.862, respectively. Arm and mean skinfold thicknesses (x, mm) could be used as the representative value for the prediction of total body fat (y, % body weight). The regression equations were: On arm y=2.00x+0.99, With mean skinfold y=1.20x+1.41 The coefficient of correlation between body weight (kg) and mean skinfold thickness was r=0.733. The ratio of mean skinfold thickness (mm) to body weight (kg) in middle-aged men was 0.132.

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Optical information storage using diffraction properties of volume hologram in Fe-LiNbO$_3$ crystal (Fe-LiNbO$_3$결정에서 부피형 홀로그램의 회절특성을 이용한 광정보 저장)

  • An, Jun-Won;Kim, Nam;Lee, Kwon-Yeon
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.35D no.6
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    • pp.63-71
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    • 1998
  • In this paper, we experiment the characteristics of coupling coefficient, gain, diffraction efficiency and dependence of time determined by TWM(Two-Wave Mixing), using Fe-LiNbO$_3$ crystal(doped with 0.015Wt.%). From these results, we proposed to apply for optical memory application. The highest coupling angle of 14。 and maximum coupling coefficient of 6.9$cm^{-1}$ / are obtained at 514.5nm wavelength. Also, maximum diffraction efficiency is 54.13% when intensity ratio and writing beam incident angle are 0.1 and 14o, respectively. After fixing process, diffraction efficiency is 21.4%. As an example, we demonstrated the writing and reconstruct optical data using spatial light modualtor and angular multiplexing in most optimal condition.

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A Molecular Dynamics Simulation Study on Hygroelastic behavior of Thermosetting Epoxy (열경화성 에폭시 기지의 흡습탄성 거동에 관한 분자동역학 전산모사)

  • Kwon, Sunyong;Lee, Man Young;Yang, Seunghwa
    • Composites Research
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    • v.30 no.6
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    • pp.371-378
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    • 2017
  • In this study, hygroelastic behavior of thermosetting epoxy is predicted by molecular dynamics simulations. Since consistent exposures to humid environments lead to macroscopic degradation of polymer composite, computational simulation study of the hygroscopically aged epoxy cell is essential for long-time durability. Therefore, we modeled amorphous epoxy molecular unit cell structures at a crosslinking ratio of 30, 90% and with the moisture weight fraction of 0, 4 wt% respectively. Diglycidyl ether of bisphenol F (EPON862) and triethylenetetramine (TETA) are chosen as resin and curing agent respectively. Incorporating equilibrium and non-equilibrium ensemble simulation with a classical interatomic potential, various hygroelastic properties including diffusion coefficient of water, coefficient of moisture expansion (CME), stress-strain curve and elastic modulus are predicted. To establish the structural property relationship of pure epoxy, free volume and internal non-bond potential energy of epoxy are examined.

Antitumor and Immunostimulating Activities of Acanthopanax sessiliflorus Fruits

  • Lee, Sang-Hyun;Lee, Yeon-Sil;Jung, Sang-Hoon;Ji, Jun;Shin, Kuk-Hyun;Kim, Bak-Kwang;Kang, Sam-Sik
    • Natural Product Sciences
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    • v.9 no.2
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    • pp.112-116
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    • 2003
  • The antitumor and immunostimulating activities of Acanthopanax sessiliflorus fruits were investigated. Polysaccharide isolated from this plant, when administered consecutively for 9 days at 50 and 100 mg/kg i.p. in mice, caused a significant increase in the life span and a significant decrease in the tumor weight and volume in mice inoculated with Sarcoma-180 tumor cells. Polysaccharide was also demonstrated to exhibit phagocytosis-enhancing activity as measured by the carbon clearance in mice. Polysaccharide, when administered i.p. at 50 and 100 mg/kg/day for 3 consecutive days, exhibited a significant RCtr/RCc [the rate of regression coefficient of the animals teated (RCtr) to that of the control (RCc)], being 1.44 (PI = 1), 1.52 (PI = 2) which was approximately the same with that of enhancement of phagocytosis, its potency as expressed by the regression coefficient ratio of zymosan (RCtr/RCc = 1.55, PI = 2), a typical phagocytosis enhancer. Polysaccharide also caused a significant increase in the acid phosphatase activity representing lysosomal enzymes in macrophages at 1-100 ig/ml in vitro in compliance with in vivo results. These results suggest that the antitumor activity of polysaccharide might be related to the immunostimulating function.

Validity on Submaximal Load Tests Using Cycle Ergometer in Evaluation of Maximum Oxygen Consumption Volume (최대 산소소모량 평가에 있어서 자전거 에르고미터를 이용한 최대하부하검사방법의 타당도)

  • Kang, Dongmug;Park, Yong Kyun;Lee, Yong Hwan;Sul, Jin Gon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.16 no.2
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    • pp.145-151
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    • 2006
  • Because of the limitations of maximal load tests for $VO_2max$, submaximal tests using cycle ergometer are used for field study in general. This study was conducted to evaluate validity of various submaximal tests using cycle ergometer. This study had been conducted during May to June 2005, which subjects were 15 males and 15 females in twenties. Experiment was performed with restrictive conditions which regulated ambient temperature, noise, and entrance restriction. Submaximal load test protocols including YMCA Protocol (YP), ${\AA}strand$-Rhyming Protocol (ARP), Relative heart ratio Protocol (RP), and Ramp test Protocol (RP) were compared with maximal load test which used gas mask analyser using Bruce Protocol. All submaximal load tests were highly related with maximal load test (Spearman's correlation coefficient > 0.60) with statistical significancy. The highest correlation coefficient with maximal test was found in RP. Three submaximal test results except RP were significantly different with maximal test results (Wilcoxon rank test). All submaximal tests had high validity. The reason why RP had highest validity might be that it represents Korean physical strength and individual differences better than the others. RP using cycle ergometer would make easy to study for physical capacity evaluation and field workload estimation.

Experimental Evaluation Method of Mass Transfer Coefficient on Biotrickling Filtration for Air Pollution Control (대기오염제어를 위한 생물살수여과법에서 물질전달계수 실험평가방법에 관한 연구)

  • Won, Yang-Soo;Jo, Wan-Keun
    • Korean Chemical Engineering Research
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    • v.53 no.4
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    • pp.482-488
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    • 2015
  • Biological treatment is promising alternative to conventional air pollution control method. Bioreactors for air pollution control have found most of their success in the treatment of dilute and high flow waste air streams containing volatile organic compounds and odor. The studies of mass transfer in biotrickling filters for air pollution control were of importance in order to control and optimize the purification process. The objectives of this study were to develop the experimental methodologies to evaluate the mass transfer coefficients of gas/liquid(trickling liquid), gas/solid(biomass) and liquid/solid in three phase biotrickling filtration. Also, this study characterized the influence factors on mass transfer such as dynamic holdup volume, gas/liquid flow rate ratio, biomass weight in reactor and recirculation rate of trickling medium for each phase of biotrickling filter.

Experimental Study of Leaching Phenomena of Cs-137 From a Cement Matrix Generated at PWR Plant (가압 경수로에서 생성된 시멘트 고화체로부터 Cs-137의 용출 현상의 실험적 연구)

  • Doh, Jeong-Yeul;Lee, Kun-Jai
    • Journal of Radiation Protection and Research
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    • v.11 no.2
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    • pp.91-103
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    • 1986
  • Experimental study for the leaching behavior of Cs-137 was carried out using the simulated evaporator bottom product of PWR plant. The method of leach test proposed by the IAEA was partially modified using ANS method. The effect of various factors, i.e., sampling method, curing temperature, curing time, leachant temperature, vermiculite addition and volume-to-surface ratio, was considered in this experiment. Diffusion model in semi-infinite slab was in a good agreement with the data obtained from 4-weeks cured specimens. The effective diffusion coefficient of the specimens which were cured at the temperature of $24^{\circ}C$ for 4 weeks was found to be $1.20{\sim}1.47{\times}10^{-11}cm^2/sec$. With the experimentally obtained diffusion coefficient ($1.47{\times}10^{-11}cm^2/sec$), long-term prediction for the leaching of Cs-137 was carried out using finite-slab approximation. The estimated fraction of Cs-137 which remains in the environment is found to be less than 0.25 percent of initial amount after 100 years. About 25 years after the beginning of leaching, its fractional amount in the environment reachs the maximum value, 0.66 percent of initial amount.

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