• Radiation Oncology Journal
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• v.30 no.4
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• pp.189-196
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• 2012

Purpose: To investigate the safety of high dose hypofractionated radiotherapy (RT) in patients with small hepatocellular carcinoma (HCC) in terms of liver volumetric changes and clinical liver function. Materials and Methods: We retrospectively reviewed 16 patients with small HCC who were treated with high dose hypofractionated RT between 2006 and 2009. The serial changes of the liver volumetric parameter were analyzed from pre-RT and follow-up (FU) computed tomography (CT) scans. We estimated linear time trends of whole liver volume using a linear mixed model. The serial changes of the Child-Pugh (CP) scores were also analyzed in relation to the volumetric changes. Results: Mean pre-RT volume of entire liver was 1,192.2 mL (range, 502.6 to 1,310.2 mL) and mean clinical target volume was 14.7 mL (range, 1.56 to 70.07 mL). Fourteen (87.5%) patients had 4 FU CT sets and 2 (12.5%) patients had 3 FU CT sets. Mean interval between FU CT acquisition was 2.5 months. After considering age, gender and the irradiated liver volume as a fixed effects, the mixed model analysis confirmed that the change in liver volume is not significant throughout the time course of FU periods. Majority of patients had a CP score change less than 2 except in 1 patient who had CP score change more than 3. Conclusion: The high dose hypofractionated RT for small HCC is relatively safe and feasible in terms of liver volumetric changes and clinical liver function.

• Resources Recycling
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• v.26 no.2
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• pp.66-70
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• 2017

The purpose of this research was to estimate density changes of sea sand by washing. To examine water content test, field density test, particle density test and measuring of dump regarding extracted sea sand and selling one. Measured result of mean particle density of barge and dump were $2.666g/cm^3$, $2.651g/cm^3$, respectively. Also, measured result of field density for each sea sand was $1.716g/cm^3$, $1.331g/cm^3$ on average. Converted to the volume of 1ton of each sea sand, $0.583m^3$, $0.751m^3$, respectively. Occurring to volume change approximately 28.8% on average. The mean field densities of measuring of sea sand that dump and barge were $1.398g/cm^3$ and $1.716g/cm^3$ respectively. This values indicated $0.715m^3$ and $0.583m^3$ each, when converted to the volume of sea sand 1ton. It was found that the average of 22.6% volume change occurred between the amount of sea sand and the sales volume.

• Journal of Korea Foundry Society
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• v.37 no.6
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• pp.199-206
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• 2017

In this study, the variations of microstructures and tensile properties of Ti-(44-54)at.%Al binary alloys were investigated. The heat-treated microstructure depended greatly on their solidification structure and annealing temperature. We measured the variations of volume fractions of primary and secondary lamellar structure as a function of the heat treatment temperature in a Ti-47at.%Al alloy. The variation of ductility as a function of Al content was in good agreement with the change of fracture mode in the tensile fracture surface. It can be inferred that the variations of yield stress and hardness of ${\gamma}$ phase in a single ${\gamma}$-phase field region are enhanced by anti-site defects created by deviations from the stoichiometric composition. In a Ti-47at.%Al alloy within the (${\alpha}_2+{\gamma}$) two-phase field, the yield stress tended to be the maximum at a near equal volume fraction of lamellar and ${\gamma}$ grains. The ductility depended sensitively on the overall grain size and Al content. The calculation of fracture strain using Chan's model indicated that the change of ductility as a function of annealing temperature was primarily determined by the variations in the overall grain size and lamellar volume fraction.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.10
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• pp.1172-1177
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• 2004

The emission control of automobile has been intensified as a part of the countermeasure to decrease air pollution in the world. As the cars with an alternative fuel starts to get into the spotlight, the cars with low emission has been introduced and exhaust gas regulation forced in this country. These days, LPG vehicles, which infrastructure of fuel was already built up, and CNG vehicles are recognized for alternative fuel cars in this country. In this study, the constant volume combustion chamber was manufactured and used for experiments to obtain the combustion characteristics of propane mixture. The combustion characteristics was analyzed, with the change of supply conditions of propane fuel. Inside the combustion chamber, the maximum temperature increase with the initial pressure is going up. The burning velocity also seems to have the same characteristic as the temperature. However, the heat flux do not change much according to the theoretical correct mixture but it changes with the various initial temperature of the combustion chamber.

• Journal of Mechanical Science and Technology
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• v.19 no.9
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• pp.1773-1780
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• 2005

The process of mould design in the foundry industry has been based on the intuition and experience of foundry engineers and designers. To bring the industry to a more scientific basis the design process should be integrated with scientific analysis such as heat transfer. The production by foundry techniques is influenced by the geometry configuration, which affects the solidification conditions and subsequent cooling. Numerical simulation and/or experiments make possible the selection of adequate materials, reducing cycle times and minimizing production costs. The main propose of this work is to study the heat transfer phenomena in the mould considering the phase change of the cast-part. Due to complex geometry of the mould, a block unstructured grid and a generalized curvilinear formulation engaged with the finite volume method is described and applied. Two types of boundary conditions, diffusive and Newtonian, are used and compared. The developed numerical code is tested in real case and the main results are compared with experimental data. The results showed that the solidification time is about 6 seconds for diffusive boundary conditions and 14.8 seconds for Newtonian boundary conditions. The use of the block unstructured grid in combination with a generalized curvilinear formulation works well with the finite volume method and allows the development of more efficient algorithms with better capacity to describe the part contours through a lesser number of elements.

• Journal of computational fluids engineering
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• v.12 no.2
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• pp.21-25
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• 2007

A general purpose program NUFLEX has been extended for two-phase flows with topologically complex interface and cavitation flows with liquid-vapor phase change caused by large pressure drop. In analysis of two-phase flow, the phase interfaces are tracked by employing a LS(Level Set) method. Compared with the VOF(Volume-of-Fluid) method based on a non-smooth volume-fraction function, the LS method can calculate an interfacial curvature more accurately by using a smooth distance function. Also, it is quite straightforward to implement for 3-D irregular meshes compared with the VOF method requiring much more complicated geometric calculations. Also, the cavitation process is computed by including the effects of evaporation and condensation for bubble formation and collapse as well as turbulence in flows. The volume-faction and continuity equations are adapted for cavitation models with phase change. The LS and cavitation formulation are implemented into a general purpose program for 3-D flows and verified through several test problems.

• Investigative Magnetic Resonance Imaging
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• v.19 no.1
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• pp.10-18
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• 2015

Background and Purpose: The association between the low emotional regulation and the brain structural change of major depressive disorder (MDD) has been proposed, but the voxel-based morphometry (VBM) studies on female MDD are rare. The purpose of the present study was to show the regional volume changes of gray matter (GM) in female patients with MDD by optimized VBM. Methods: To control subjects homogeneity, twenty female MDD patients and age, sex matched 21 normal controls were included for the VBM analysis. To identify the change of regional gray matter volume (GMV), the optimized VBM was performed with T1 MRIs. The amounts of gray/white matter and intracranial cavity volumes (ICV) were measured. The analysis of covariance (ANCOVA) and partial correlation analyses covariate with age and ICV were applied for VBM. Results: The age and ICV distributions were similar between the two groups. In the ANCOVA, the total GMV of MDD was smaller than that of normal controls. In the VBM, regional GMV was relatively decreased in the limbic system (amygdalae, ambient gyri, hippocampi heads, subiculum, posterior parahippocampal gyri, pulvinar nuclei, dorsal posterior cingulate gyri, and left pregenual cingulate gyrus). The lingual gyri, short insular gyri, right fusiform gyrus, and right inferior frontal gyrus were also showed decreased regional GMV. Conclusion: The results of this study indicate that the female MDD is mainly associated with the structural deficits of the limbic system and limbic system related cortices, which were known to the center of emotions.

• Archives of Pharmacal Research
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• v.10 no.2
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• pp.94-99
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• 1987

By using the former equation (8), we modified the equation which can show the dissimilar osmotic behavior of liposome with composition change. The slope of the new equation was presented as the ratio of osmotically active volume (V$_{act}$= ) to the total volume (V$_{totel}$= $_{acl}$+ V$_{dead}$ ; V$_{dead}$ is osmotically inactive volume) of loposomes, we defined is as a Z-value, which can elucidate the dissimilarity of the osmotic activity of multilamellar liposomes with the change of phospholipid composition and the differences of physicochemical properties of liposomes. Z-value was applied for studying the physico-chemical properties of liposomal membrane. The factor that affects on the Z-value was not the lipid concentration of liposome stock dispersion but the lipid composition of liposomal membrane. As the content of dicetylphosphate, the negative charged phospholipid, was increased, the osmotic activity, represented by Z-value, of multilamellar liposome was decreased. Using the hypertonic conditions (shrinking region), Z-value steadily increased and reached a maximum at 10 mole percent cholesterol with increasing the cholesterol content.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.1
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• pp.186-192
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• 2007

In general, pulsation damper is installed in fuel rail for conventional MPI engine to decrease undesirable noise in vehicle cabin room. However, pulsation damper is so expensive that there are prevailing studies to reduce fuel pressure pulsations with integrated damping effect. This paper is one of basic studies for development of fuel rail to abate pulsations with self-damping effect. Primarily, the pressure pulsation characteristics was investigated with aspect ratio of cross section, wall thickness, and materials of fuel rail. A high aspect ratio or thin wall was found to absorb the pressure pulsations effectively. But volume effects on the fuel pressure pulsation reductions were not especially significant than cross section effects because volume increment rate is larger than pressure pulsation reduction rate. The fuel rail made of aluminum is effective for reduction of pressure pulsation than that of low-carbon steel. Pressure change period increases on the basis of same lengths of supply line and fuel rail as the volume is enlarged and/or the thickness of wall is thinned.

• Nuclear Engineering and Technology
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• v.54 no.7
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• pp.2359-2366
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• 2022

Selecting graphite grades with superior irradiation characteristics is important task for designers of graphite moderation reactors. To provide reference information and data for graphite selection, the effects of irradiation on three fine-grained, iso-molded nuclear grade graphites, ETU-10, IG-110, and NBG-25, were compared based on irradiation-induced changes in volume, thermal conductivity, dynamic Young's modulus, and coefficient of thermal expansion. Data employed in this study were obtained from reported irradiation test results in the high flux isotope reactor (HFIR)(ORNL) (ETU-10, IG-110) and high flux reactor (HFR)(NRL) (IG-110, NBG-25). Comparisons were made based on the irradiation dose and irradiation temperature. Overall, the three grades showed similar irradiation-induced property change behaviors, which followed the historic data. More or less grade-sensitive behaviors were observed for the changes in volume and thermal conductivity, and, in contrast, grade-insensitive behaviors were observed for dynamic Young's modulus and coefficient of thermal expansion changes. The ETU-10 of the smallest grain size appeared to show a relatively smaller VC to IG-110 and NBG-25. Drastic decrease in the difference in thermal conductivity was observed for ETU-10 and IG-110 after irradiation. The similar irradiation-induced properties changing behaviors observed in this study especially in the DYM and CTE may be attributed to the assumed similar microstructures that evolved from the similar size coke particles and the same forming method.