• Title/Summary/Keyword: Visual changes

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Determinants of Opioid Efficiency in Cancer Pain: a Comprehensive Multivariate Analysis from a Tertiary Cancer Centre

  • Goksu, Sema Sezgin;Bozcuk, Hakan;Uysal, Mukremin;Ulukal, Ece;Ay, Seren;Karasu, Gaye;Soydas, Turker;Coskun, Hasan Senol;Ozdogan, Mustafa;Savas, Burhan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.21
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    • pp.9301-9305
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    • 2014
  • Background: Pain is one of the most terrifying symptoms for cancer patients. Although most patients with cancer pain need opioids, complete relief of pain is hard to achieve. This study investigated the factors influencing persistent pain-free survival (PPFS) and opioid efficiency. Materials and Methods: A prospective study was conducted on 100 patients with cancer pain, hospitalized at the medical oncology clinic of Akdeniz University. Patient records were collected including patient demographics, the disease, treatment characteristics, and details of opioid usage. Pain intensity was measured using a patient self-reported visual analogue scale (VAS). The area under the curve (AUC) reflecting the pain load was calculated from daily VAS tables. PPFS, the primary measure of opioid efficacy, was described as the duration for which a patient reported a greater than or equal to two-point decline in their VAS for pain. Predictors of opioid efficacy were analysed using a multivariate analysis. Results: In the multivariate analysis, PPFS was associated with the AUC for pain (Exp (B)=0.39 (0.23-0.67), P=0.001), the cumulative opioid dosage used during hospitalisation (Exp (B)=1.00(0.99-1.00), P=0.003) and changes in the opioid dosage (Exp (B)=1.01 (1.00-1.01), P=0.016). The change in VAS score over the standard dosage of opioids was strongly associated with current cancer treatment (chemotherapy vs. others) (${\beta}=-0.31$, T=-2.81, P=0.007) and the VAS for pain at the time of hospitalisation (${\beta}=-0.34$, T=-3.07, P= 0.003). Conclusions: The pain load, opioid dosage, concurrent usage of chemotherapy and initial pain intensity correlate with the benefit received from opioids in cancer patients.

Enhancing Multicultural Education in the Context of the 2007 Revised Home Economics Education Curriculum - Based on the Analysis of 7th Grade Course Book - (가정과교육에서의 개정 교육과정의 과제와 방향 - 2007년 개정 교육과정에 따른 7학년 교과서 분석 결과를 기초로 -)

  • Kim, Eun-Jeung
    • Journal of Korean Home Economics Education Association
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    • v.22 no.2
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    • pp.81-99
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    • 2010
  • This study was motivated by the fact that the educational curriculum needs revising as the contemporary society undergoes dramatic changes; this change demonstrates that Korea society now turns into a multicultural community. In this vein, this study aims to examine how the national Home economics curriculum (revised in 2007) incorporated the essence of multicultural education program and that of international understanding program into the coursebook, and to suggest which part of the coursebook needs revising to enhance its validity. To attain this goal, this research was conducted to analyze how two programs are implemented in secondary school, and to propose how those programs should be developed to address the immediate needs of the current society. To illustrate, this study examines a variety of theories and methodology on how multicultural education program should be implemented along with the current situation of Korea society. In addition, quantitative research was conducted to acquire empirical data from 6 coursebooks the frequencies of statements and visual aids that are considered to be directly reflect the essence of two programs. The results demonstrate that two programs are relegated into a lesser position compared to other programs; furthermore, they lack materials to deepen students' understanding about multicultural society and international relations. Therefore, the considerable revision needs to be conducted to embrace the essence of multicultural society and international understanding programs, and sensitize students to the immediate needs of the current society.

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Development of 3-D GIS based Expression System for Utilization of Submarine Mineral Resource Exploration Data (해저자원 탐사자료의 효율적인 활용을 위한 3차원 GIS 기반의 표출 시스템 설계 및 구축)

  • Kim, Dong Il;Kim, Kye Hyun;Lee, Sung Joo;Park, Yong Hyun
    • Spatial Information Research
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    • v.21 no.3
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    • pp.21-30
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    • 2013
  • Recently, interest of submarine mineral resources has been increasing from the depletion of land resources around the world and many countries are involving in submarine mineral resource exploration work. South Korea is also in progress of mineral exploration and relevant study to ensure the submarine mineral resources from around the Korean Peninsula. As a result, the submarine mineral resource exploration data have been increasing annually. A database and 2D GIS-based system have been constructed for the management of the data. However, submarine mineral resource exploration data is explored and created on the sea-bed. Consequently, the visual confirmation of the water levels and marine landform is important for high dimension analysis. Therefore, the major aims of this study are to collect marine landform data from around the Korean Peninsula and to develop 3 dimension GIS based system that is linked to the submarine mineral resource exploration data. In detail, marine landform data were acquired for the Korean Peninsula and they were interpolated into raster file format. The raster file was then processed to be easily used and was entered into an Oracle database. Based on this database, 3D expression and overlap function between marine landform data and submarine mineral resource exploration data were designed using ArcScene offered by the ESRI. After design, 3D GIS based expression system was developed. Confirmations of locations and changes in the submarine mineral resource exploration data based on 3D GIS are enabled to support the efficient application of the proposed system. It is expected that this system will be highly useful for estimating the reserves of mineral resources and for providing valuable information for economic evaluations.

Effects of Ultraviolet Radiation on the Skin (자외선에 의한 피부반응)

  • Youn, Jail-Il
    • Journal of Radiation Protection and Research
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    • v.20 no.3
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    • pp.181-186
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    • 1995
  • UV irradiation causes a variety of biologic effects on the skin. These effects can be devided to acute reactuons and chronic reacxtions by duration of UV irradiation. Acute reactions are erythema reaction, pigment reactions and changes in epidermal thickness. Among them erythema reaction is most common and conspicuous acute effects of the skin. Upon exposure to sun or artificial UV soures, a faint redness response of skin may begin. Larger exposure causes sunburn reaction which is exaggerated erythema reactionassociated with pain, swelling, vesicle and dulla. Extent and time course of erythema reaction depend upon several factors including wavelength and dose of UVR, skin conditions likeas skin type, site, color, temperature, humidity and environmental factors. Evaluation of erythema erythema induced by UV irradiation is difficult to quantify. Degree of redness of skin are usually estimated by subjective visual evaluation. The lowest exposure dose required to protuce erythema is called minimal erythema dose (mod). Repeated exposures of UVR result in photaging skin. In this condition we can see wrinkling, skin atrophy, dilated blood vessels and keratoses. In sensitive persons photocarcinogenesis is can Be developed on exposed area of skin. Recently skin canser is increasing now in our country. An effective public education and photopreventive method must be developed.

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Visual Contents Study of Historic Re-create about Memory of China 6th Generation Director (중국 6세대 감독의 기억에 관한 역사적 재현 영상콘텐츠 연구)

  • Han, Dal-Ho
    • The Journal of the Korea Contents Association
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    • v.10 no.2
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    • pp.155-164
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    • 2010
  • This dissertation is considered a historic generation that Chinese film $6^{th}$ director remembers through their life. Also it is figured out historic anguish and hurt how it was remembered and appeared in film. They have made actual films through their efforts which are different from the conventional generation. In addition, between memory and oblivion the time's signification in the history is showed how what way can be represented. It was presented the time's anguish through memory's metaphor in Chinese film $6^{th}$ works. Also, it was shown the existence's reality from dream was losing as memory was hiding between desire and despair. Additionally, the self of daily was expressed to unconcernedly accept reality, and its against the unchangeable world's eye and memory. The $6^{th}'s$ films' desire was expressed passive appearance to accept reality with losing dream in these three things; cannot be reality in the process to figure out own natural character, and appearance to keep traditional character, finally gradually changing reality. When $6^{th}$ directors analysis the history as memory, social repression follows family's repression, family's repression brings personal repression, and then repression changes to desire, finally the life as a reaction could be maintained. In conclusion, personal desire was covered for fantasy, and the overcoming figure was represented. Moreover, Chinese face that $6^{th}$ directors have memorized was presented through these sentiments.

A Study on the Effect of Intermittent Exotropia Vision Training Using Proprioceptive Test (Maindot test) (양안시 고유수용감각검사(Maindot 검사)를 사용한 간헐성 외사시안의 시기능 훈련효과에 대한 연구)

  • Lee, Chang-Seon;Bae, Youn-Joo;Kim, Jung-Bok;Kim, Ki-Hong
    • Journal of Korean Ophthalmic Optics Society
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    • v.21 no.3
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    • pp.243-251
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    • 2016
  • Purpose: This study evaluates the effectiveness of intermittent exotropia vision training through follow up of average 3 years using proprioceptive test (Maindot test). Methods: 35 people (18 men, 17 women) with mean age of 13.48 (${\pm}2.45$) with corrected visual acuity of 0.9 or higher and normal binocular vision and control were observed for changes between before, after, and 3 years following the vision training during the period from 2005 to 2009. Results: After training, the correlation between the changed amount of deviation and PRC(diplopia) value and symptoms was not significant (p>0.05). However, it showed a statistically significant (p<0.001) correlation that change of the binocular proprioceptive sense abilities is decreased subjective symptoms. Conclusions: Binocular proprioceptive sense may be used in variety of purposes and applications such as predictive evaluation of binocular symptoms, binocular function performance evaluation after vision training and prism treatment.

Changes of Dynamic Stereoacuity Depending on Distance between Rods and Rod Thickness in Three Rods Test (세막대 검사에서 막대 간 거리와 막대두께 차이에 의한 동적입체시력의 변화)

  • Han, Kyung-Do;Lee, Min-Jae;Kim, Sang-Yeob;Moon, Byeong-Yeon;Yu, Dong-Sik;Cho, Hyun Gug
    • Journal of Korean Ophthalmic Optics Society
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    • v.21 no.3
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    • pp.253-257
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    • 2016
  • Purpose: To determine whether the distance between objects and the size of object are factors to be able to affect dynamic stereoacuity. Methods: Subjects were 37 adults (26 males and 11 females) with an average age of $23.89{\pm}1.76$. Refractive error was fully corrected for all subjects and each visual acuity of them was over 0.9. Three rods test was performed for measurement of stereoacuity. The viewing angles from left rod to right rod were set $5^{\circ}$, $10^{\circ}$, and $15^{\circ}$ and the rod thickness used 7 mm, 14 mm, and 21 mm, respectively. Stereoacuity was repeatedly measured three times in each test condition at 2.5 m distance, and reported the average value of them. Results: When rod thickness was 7 mm or 14 mm, dynamic stereoacuity decreased as the viewing angle increased, and they were significantly decreased (p<0.01) at viewing angles of $10^{\circ}$ and $15^{\circ}$ as compared with that of at $5^{\circ}$, respectively. When rod thickness was 21 mm, dynamic stereoacuity decreased as the viewing angle increased, especially, that of at $15^{\circ}$ decreased significantly (p<0.01) as compared with that of at $5^{\circ}$. The dynamic stereoacuity depending on the rod thickness have an increasing tendency as the rod thickness increased. Conclusions: The viewing angle between objects and the size of viewing object were factors that affect to dynamic stereoacuity.

Effects of Preemptive Analgesia with Parecoxib Sodium on Haemodynamics and Plasma Stress Hormones in Surgical Patients with Thyroid Carcinoma

  • Wang, Lian-Dong;Gao, Xia;Li, Jun-Ying;Yu, Hong-Yan;Su, Hai-Wen;Liu, Lian-Zhong;Qi, Jun
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.9
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    • pp.3977-3980
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    • 2015
  • Background: To investigate the effects of preemptive analgesia with parecoxib sodium on haemodynamics and plasma stress hormones in surgical patients with thyroid carcinoma. Materials and Methods: Fifty-seven patients with thyroid carcinoma who underwent thyroidectomy selectively in Laiwu Hospital Affiliated to Taishan Medical University and Binzhou People's Hospital were selected and randomly divided into three groups, 19 cases in each group. The control group was intravenously injected 0.9% sodium chloride injection before anesthesia induction; trial group I was intravenously injected with parecoxib sodium 20 min before anesthesia induction; based on trial group I, trial group II was injected with parecoxib sodium again 12 h after surgery. The levels of plasma norepinephrine (NE), cortisol (Cor) and blood glucose before, 12 and 24 h after surgery and changes of haemodynamics before surgery, at the end of surgery and 12, 24 and 48 h after surgery were compared in the three groups. Besides, visual analogue scale (VAS) scores were recorded 4, 8, 12 and 24 h after surgery. Results: 12 and 24 h after surgery, the levels of plasma NE and Cor in three groups rose dramatically (P<0.05 or (P<0.01); The levels of plasma NE and Cor in trial groups I and II were evidently lower than in control group (P<0.05 or P<0.01), and those in trial group II slightly lower than in trial group I. 12 h after surgery, the heart rates (HR) and systolic pressures (SBP) in trial groups I and II increased obviously by comparison to surgery before (P<0.05 or P<0.01), but gradually returned to the preoperative level. HR, SBP and diastolic pressures (DBP) in trial groups I and II at the end of surgery and 12 h after surgery were all lower than in the control group, and significant differences were present (P<0.05 or (P<0.01). At 4, 8, 12 and 24 h after surgery, VAS scores in trial groups I and II were markedly lower than in the control group (P<0.05 or (P<0.01), the scores in trial group II being the lowest. Conclusions: Combined application of parecoxib sodium for preemptive analgesia before anesthesia and after surgery can effectively reduce the levels of plasma stress hormones and improve analgesic effects in surgical patients with thyroid carcinoma, and without conspicuous impact on haemodynamics.

An Input/Output Technology for 3-Dimensional Moving Image Processing (3차원 동영상 정보처리용 영상 입출력 기술)

  • Son, Jung-Young;Chun, You-Seek
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.35S no.8
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    • pp.1-11
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    • 1998
  • One of the desired features for the realizations of high quality Information and Telecommunication services in future is "the Sensation of Reality". This will be achieved only with the visual communication based on the 3- dimensional (3-D) moving images. The main difficulties in realizing 3-D moving image communication are that there is no developed data transmission technology for the hugh amount of data involved in 3-D images and no established technologies for 3-D image recording and displaying in real time. The currently known stereoscopic imaging technologies can only present depth, no moving parallax, so they are not effective in creating the sensation of the reality without taking eye glasses. The more effective 3-D imaging technologies for achieving the sensation of reality are those based on the multiview 3-D images which provides the object image changes as the eyes move to different directions. In this paper, a multiview 3-D imaging system composed of 8 CCD cameras in a case, a RGB(Red, Green, Blue) beam projector, and a holographic screen is introduced. In this system, the 8 view images are recorded by the 8 CCD cameras and the images are transmitted to the beam projector in sequence by a signal converter. This signal converter converts each camera signal into 3 different color signals, i.e., RGB signals, combines each color signal from the 8 cameras into a serial signal train by multiplexing and drives the corresponding color channel of the beam projector to 480Hz frame rate. The beam projector projects images to the holographic screen through a LCD shutter. The LCD shutter consists of 8 LCD strips. The image of each LCD strip, created by the holographic screen, forms as sub-viewing zone. Since the ON period and sequence of the LCD strips are synchronized with those of the camera image sampling adn the beam projector image projection, the multiview 3-D moving images are viewed at the viewing zone.

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Study on Changes of Hair and Scalp Characteristics by Keratin Peptides (케라틴 펩타이드에 의한 모발 및 두피 특성 변화 연구)

  • Nam, Gaewon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.45 no.4
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    • pp.353-361
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    • 2019
  • Using Fervidobacterium islandicum AW-1, keratin peptides were produced and confirmed factors related to the scalp and hair. The cytotoxicity and proliferation tests as a function of the concentration of the keratin peptide did not show toxicity and effect on the cellular proliferation in the immortalized human hair dermal papilla cell line. Hair shampoos and hair essences containing keratin peptides were produced, and conducted human patch test. Result showed no skin irritation. The shampoo and the essence were apploed to 2 groups of 30 healthy adults for 4 weeks and showed statistically significant positive results for gloss, hair loss, scalp trouble, and hair roughness by visual assessment. The scalp water content was significantly increased after 2 and 4 weeks compared to before using the shampoo or the essence. Trans-epidermal water loss (TEWL) and the sebum secretion amount in the scalp were significantly decreased after 4 weeks compared to before. The frictional force against combing before and after using the hair shampoo and the essence for normal hair tress and damaged hair tress was significantly changed. The combing force was increased for normal hair tress and decreased for damaged hair tress. In conclusion, we suggest that keratin peptides are appropriated as cosmetic ingredients to be used in hair and scalp related products.