• 제목/요약/키워드: Vascular index

검색결과 376건 처리시간 0.028초

영종도와 용유도 일대의 식물상 (Distribution of Vascular Plants in Youngjongdo and Yongyudo)

  • 이혜정;박수현;하상교;황희숙;장계선;이유미
    • 한국환경생태학회지
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    • 제26권6호
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    • pp.839-867
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    • 2012
  • 2009년 5월부터 동년 10월까지의 5회 조사, 그리고 2011년 7월 1회의 추가조사로 총 6회에 걸쳐 인천광역시 중구 영종도와 용유도에 자생하는 관속식물의 현지조사를 실시하였다. 조사된 소산식물은 98과 352속 556종 4아종 73변종 11품종으로 총 644분류군이다. 이들 중 모래지치, 갯사상자, 큰조뱅이, 참지네고사리, 홍지네고사리를 포함한 250 분류군의 분포가 새롭게 확인되었다. 관속식물의 생활형 중 휴면형은 반지중식물이 37.1%로 가장 높게 나타났다. 한국 특산식물은 총 4분류군, 한국 희귀식물은 6분류군, 식물구계학적 특정식물종은 총 39분류군이 확인되었다. 귀화식물은 95분류군이 조사 되었으며, 도시화지수는 29.6%로 매우 높게 나타났다.

Antioxidative Properties of Brown Algae Polyphenolics and Their Perspectives as Chemopreventive Agents Against Vascular Risk Factors

  • Kang, Keejung;Park, Yongju;Hwang, Hye-Jeong;Kim, Seong-Ho;Lee, Jeong-Gu;Shin, Hyeon-Cheol
    • Archives of Pharmacal Research
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    • 제26권4호
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    • pp.286-293
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    • 2003
  • Several polyphenolic compounds and complex mixtures were isolated from brown algae species. The 1,1-diphenyl-2-picryhydarzyl (DPPH) radical scavenging activity and ferric reducing antioxidant power (FRAP) of these compounds were evaluated to determine their physiological usefulness as antioxidants for vascular protection. The antioxidative protection of low-density lipoprotein (LDL) was also evaluated and compared with that of catechin, because the generation of oxidized LDL is one of the most active and specific risk factors contributing to atherogenesis. Oral administration to rats of a commercially available sample ($VNP^{TM}$) containing 30% of these polyphenolic compounds and 70% dietary fiber revealed that the serum reducing capacity measured in terms of FRAP value was significantly elevated 30 min after the treatment, but declined rather quickly thereafter, indicating the good oral absorption of the compounds and their fast binding to the lumenal surface of the blood vessels. An eight-week, human, clinical trial (n=31) of $VNP^{TM}$ showed significant improvement in erectile function measured by IIEF (international index of erectile function) score. These results collectively demonstrated the usefulness of these polyphenolic compounds as fundamental chemopreventive agents against vascular risk factors originating from oxidative stress.

Early dropout predictive factors in obesity treatment

  • Michelini, Ilaria;Falchi, Anna Giulia;Muggia, Chiara;Grecchi, Ilaria;Montagna, Elisabetta;De Silvestri, Annalisa;Tinelli, Carmine
    • Nutrition Research and Practice
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    • 제8권1호
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    • pp.94-102
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    • 2014
  • Diet attrition and failure of long term treatment are very frequent in obese patients. This study aimed to identify pre-treatment variables determining dropout and to customise the characteristics of those most likely to abandon the program before treatment, thus making it possible to modify the therapy to increase compliance. A total of 146 outpatients were consecutively enrolled; 73 patients followed a prescriptive diet while 73 followed a novel brief group Cognitive Behavioural Treatment (CBT) in addition to prescriptive diet. The two interventions lasted for six months. Anthropometric, demographic, psychological parameters and feeding behaviour were assessed, the last two with the Italian instrument VCAO Ansisa; than, a semi-structured interview was performed on motivation to lose weight. To identify the baseline dropout risk factors among these parameters, univariate and multivariate logistic models were used. Comparison of the results in the two different treatments showed a higher attrition rate in CBT group, despite no statistically significant difference between the two treatment arms (P = 0.127). Dropout patients did not differ significantly from those who did not dropout with regards to sex, age, Body Mass Index (BMI), history of cycling, education, work and marriage. Regardless of weight loss, the most important factor that determines the dropout appears to be a high level of stress revealed by General Health Questionnaire-28 items (GHQ-28) score within VCAO test. The identification of hindering factors during the assessment is fundamental to reduce the dropout risk. For subjects at risk, it would be useful to dedicate a stress management program before beginning a dietary restriction.

혈관내피세포성장인자 억제제에 의한 구강편평상피세포암종 세포주의 성장 억제 효과 (ANTI-TUMOR EFFECTS OF VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITOR ON ORAL SQUAMOUS CELL CARCINOMA CELL LINES)

  • 한세진;이재훈
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제35권2호
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    • pp.66-73
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    • 2009
  • Tumor angiogenesis is a process leading to formation of blood vessels within tumors and is crucial for maintaining a supply of oxygen and nutrients to support tumor growth and metastasis. Vascular endothelial growth factor(VEGF) plays a key role in tumor angiogenesis including induction of endothelial cell proliferation, migration, survival and capillary tube formation. VEGF binds to two distinct receptors on endothelial cells. VEGFR-2 is considered to be the dominant signaling receptor for endothelial cell permeability, proliferation, and differentiation. Bevacizumab(Avastin, Genetech, USA) is a monoclonal antibody against vascular endothelial growth factor. It is used in the treatment of cancer, where it inhibits tumor growth by blocking the formation of new blood vessels. The goal of this study is to identify the anti-tumor effect of Bevacizumab(Avastin) for oral squamous cell carcinoma cell lines. Human squamous cell carcinoma cell line(HN4) was used in this study. We examined the sensitivity of HN4 cell line to Bevacizumab(Avastin) by using in vitro proliferation assays. The results were as follows. 1. In the result of MTT assay according to concentration of Bevacizumab(Avastin), antiproliferative effect for oral squamous cell carcinoma cell lines was observed. 2. The growth curve of cell line showed the gradual growth inhibition of oral squamous cell carcinoma cell lines after exposure of Bevacizumab(Avastin). 3. In the apoptotic index, groups inoculated Bevacizumab(Avastin) were higher than control groups. 4. In condition of serum starvation, VEGFR-2 did not show any detectable autophosphorylation, whereas the addition of VEGF activated the receptor. Suppression of phosphorylated VEGFR-2 and phosphorylated MAPK was observed following treatment with Bevacizumab(Avastin) in a dose-dependent manner. 5. In TEM view, dispersed nuclear membrane, scattered many cytoplasmic vacuoles and localized chromosomal margination after Bevacizumab(Avastin) treatment were observed. These findings suggest that Bevacizumab(Avastin) has the potential to inhibit MAPK pathway in proliferation of oral squamous cell carcinoma cell lines via inhibition of VEGF-dependent tumor growth.

충남 오서산과 봉수산의 식물상 및 관리방안 (Management Methods and Vascular Plants of the Ohseosan and the Bongsusan, Chungnam)

  • 오현경;김동필;오구균;강기래;배중남
    • 한국환경복원기술학회지
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    • 제16권3호
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    • pp.63-81
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    • 2013
  • The vascular plants in the Ohseosan and the Bongsusan, Chungnam were listed 439 taxa (9.0% of all 4,881 taxa of vascular plants); 95 families, 268 genera, 339 species, 5 subspecies, 75 varieties and 20 forms. Furthermore, the Ohseosan were listed 339 taxa and the Bongsusan were listed 306 taxa. So, Hemicryptophytes (H) were 107 taxa (24.4%), Therophytes (Th), Geophytes (G) same as were 82 taxa (18.7%) showed high proportional ratio in life form. Based on the list of rare plants, 4 taxa; Aristolochia contorta, Viola albida, Scutellaria insignis (LC) and Scrophularia koraiensis (DD) and endemic plants, 8 taxa; Aconitum pseudolaeve, Ajuga spectabilis, etc. Based on the list of specific plants, 35 taxa; Wisteria floribunda for. floribunda in class IV, 5 taxa (Scutellaria insignis, Scrophularia koraiensis, etc.) in class III, 5 taxa (Acer triflorum, Cymopterus melanotilingia, etc.) in class II, 24 taxa (Pyrus ussuriensis var. ussuriensis, Campanula punctata, etc.) in class I. Based on the list of naturalized plants, 9 families, 20 genera, 24 taxa (Persicaria orientalis, Carduus crispus, etc.) and ecosystem disturbing plants were Rumex acetocella, Ambrosia artemisiifolia. Naturalization rate was 5.5% of all 439 taxa of vascular plants and urbanization index was 7.5% of all 321 taxa of naturalized plants. In particular, for rare plants, in and ex-situ conservation of genetic resources must surely be done, by preserving present natural habitats, discovering additional natural habitats and securing seeds. Moreover, ecosystem disturbing plants require long-term monitoring and consistent management, since not only do they disturb the ecosystem in competition with Korean native species, but damage humans, too.

검마산(경북 영양) 관속식물의 분포 (Distribution of Vascular Plants in Geommasan (Yeongyang, Gyeongbuk))

  • 유병찬;정형진;박명순;이선희;최하나;정수영;정규영
    • 한국자원식물학회지
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    • 제20권4호
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    • pp.281-291
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    • 2007
  • 본 연구는 경북 영양군 검마산(해발 1,0l7m, 북위 $36^{\circ}\;42^{'}\;30.0^{"}{\sim}36^{\circ}\;45^{'}\; 30.1^{"}$, 동경 $129^{\circ}\;12^{'}\;30.0^{"}{\sim}129^{\circ}\;18^{'}\; 00.0^{"}E$)의 관속식물 분포를 파악하기 위하여 수행되었다. 2004년 4월부터 2006년 10월까지 11회에 걸쳐 채집된 관속식물은 총 91과 318속 424종 3아종 73변종 13품종의 총 513종류로 정리되었으며, 이들을 유용성에 따라 구분하면 식용 243종류, 약용 307종류, 공업용 122종류, 관상용 85종류, 용도가 밝혀지지 않은 식물 77종류이었다. 특기할만한 식물로는 한국특산식물이 9종류, 환경부지정 법적 보호식물 4종류, 귀화식물이 21종류로서 귀화율은 4.1%, 도시화지수는 7.5%로 나타났다.

일월산(경북)의 관속식물상 (Flora of vascular plants in Irwolsan of Gyeongbuk)

  • 정형진;남기흠;박재호;정규영
    • 한국자원식물학회지
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    • 제18권1호
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    • pp.131-147
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    • 2005
  • 본 연구는 경북 영양군 일월산(해발 1218.5m, 북위 $36^{\circ}\;45'\;00'\~36^{\circ}\;50'\;10'$, 동경 $129^{\circ}\;02'\;50'\~129^{\circ}\;09'\;00'$)의 관속식물 분포를 파악하기 위하여 수행되었다. 2002년 5월부터 2003년 5월까지 16회에 걸쳐 채집된 관속식물은 총 105과 381속 618종 6아종 104변종 12품종의 총 740종류로 정리되었으며, 이들을 유용성에 따라 구분하면 식용 315종류, 약용 428종류, 공업용 100종류, 관상용 84종류, 용도가 밝혀지지 않은 식물 201종류이었다. 특기할만한 식물로는 한국특산식 물이 22종류, 환경 부지정 법적보호종이 6종류, 귀화식물이 27종류로서 귀화율은 $3.6\%$, 도시화지수는 $9.7\%$로 나타났다.

북한산국립공원 주요지역의 관속식물상 -북한산 둘레길, 진관내동 습지, 북한동 철거지를 대상으로- (Vascular Plants of Major Sites in Bukhansan National Park -A Case Study on Bukhansan Dulegil, Jingwan-dong Wetland, Bukhan-dong Cheolgeoji-)

  • 오현경;한윤희;조우
    • 한국환경복원기술학회지
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    • 제15권1호
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    • pp.35-51
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    • 2012
  • The vascular plants in Bukhansan Dulegil, Jingwan-dong Wetland and Bukhan-dong Cheolgeoji were listed 432 taxa (8.9% of all 4,881 taxa of vascular plants); 95 families, 274 genera, 345 species, 2 subspecies, 69 varieties and 16 forms. Divided into woody plants were 145 taxa (33.6%) and herbaceous plants were 287 taxa (66.4%). The Bukhansan Dulegil were listed (Myeongsang-gil 159 taxa, Huingureum-gil 227 taxa, Wooyiryeong-gil 216 taxa, Banghakdong-gil 139 taxa, Boru-gil 199 taxa), Jingwan-dong Wetland were listed 147 taxa and Bukhan-dong Cheolgeoji were listed 129 taxa. Based on the list of rare plants by Korea Forest Service and Korea National Arboretum were Viola albida Palibin (Violaceae), Iris minutiaurea Makino (Iridaceae) and Korea National Arboretum were endemic plants, Philadelphus schrenkii Rupr. var. schrenkii (Saxifragaceae), Weigela subsessilis L.H. Bailey (Caprifoliaceae). Based on the list of floristic regional indicator plants by Korean Ministry of Environment were total 22 taxa; Wisteria floribunda DC. for. floribunda in class IV, 3 taxa (Betula davurica Pall., Mukdenia rossii Koidz., Glechoma grandis Kuprian., etc.) in class III, 5 taxa (Acer triflorum Kom., Viola orientalis W. Becker, Heloniopsis koreana Fuse & Al., etc.) in class II and 13 taxa (Camptosorus sibiricus Rupr., Clematis patens C. Morren & Decne., Cirsium pendulum Fisch. ex DC., etc.) in class I. Based on the list of naturalized plants, 16 families, 35 genera, 37 species, 3 varieties, 1 form, total 41 taxa (Rumex crispus L., Abutilon theophrasti Medicus, Panicum dichotomiflorum Michx. etc.), naturalization rate was 9.5% of all 432 taxa of vascular plants and urbanization index was 13.3% of all 309 taxa of naturalized plants. Ecosystem disturbing wild plants were 5 taxa; Rumex acetocella L., Ambrosia artemisiifolia L., Ambrosia trifida L. var. trifida, Eupatorium rugosum Houtt., Aster pilosus Willd.

뇌내출혈 이후 발생한 혈관성 치매 환자에 대한 귀비탕가미방 치험 1례 (A Case Report of a Patient with Vascular Dementia Caused by Intracerebral Hemorrhage Treated with Modified Guibi-tang)

  • 윤혜수;이은창;손정민;권선우;박충현;권이재;이효정;이정은
    • 대한한방내과학회지
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    • 제44권5호
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    • pp.1033-1040
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    • 2023
  • Objectives: The aim of this study is to describe the effects of traditional Korean medicine treatment on a patient with vascular dementia caused by an intracerebral hemorrhage. Methods: The patient was treated with herbal medicine (modified Guibi-tang) and acupuncture. The effects of these treatments were evaluated using the Korean Mini Mental Status Examination (K-MMSE-2), Cognitive Dementia Rating (CDR), Manual Muscle Test (MMT), Korean version of Modified Barthel Index (K-MBI), and Videofluoroscopic Swallow Study (VFSS). Results: After treatment, the K-MMSE-2 score, CDR score, MMT, K-MBI, and VFSS improved. Conclusion: The results suggest that traditional Korean medicine may be effective for the symptoms of vascular dementia caused by intracerebral hemorrhage.

폐쇄성 수면 무호흡이 Soluble Intercellular Adhesion Molecule-1과 Vascular Endothelial Growth Factor에 미치는 영향 (Influence of Obstructive Sleep Apnea on Soluble Intercellular Adhesion Molecule-1 and Vascular Endothelial Growth Factor)

  • 김정표;이상학;권순석;김영균;김관형;송정섭;박성학;문화식
    • Tuberculosis and Respiratory Diseases
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    • 제56권4호
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    • pp.364-373
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    • 2004
  • 연구배경 : 폐쇄성 수면 무호흡 증후군은 고혈압과 심부정맥 및 허혈성 심질환 등의 심혈관질환을 일으키는 위험요소로 알려져 있으나 정확한 기전에 대해서는 아직 확실히 밝혀져 있지 않다. 최근에 soluble intercellular adhesion molecule-1(sICAM-1)과 vascular endothelial growth factor(VEGF)가 죽상경화증의 발생과 진행에 관여한다고 알려지면서, 일부 연구에서는 이러한 사이토카인이 폐쇄성 수면 무호흡 증후군에서도 증가한다고 보고하였다. 저자는 폐쇄성 수면 무호흡 증후군 환자에서 sICAM-1과 VEGF의 농도 변화를 관찰함으로써, 이들 환자에서 동반될 수 있는 심혈관질환 발생의 병태생리를 일부 이해하고자 하였다. 방 법 : 폐쇄성 수면 무호흡 증후군을 진단하기 위해 가톨릭대학교 성바오로병원 수면장애크리닉을 방문하여 수면다원검사를 시행한 37명을 대상으로 하였다. 철야 수면다원검사를 종료한 직후 혈액 채취를 한 후 혈청분리를 하여 $-70^{\circ}C$ 냉장고에 보관하였다. 사이토카인의 측정은 ELISA 방법으로 시행하였고 수면다원검사의 각 지표와 혈청 sICAM-1 농도 및 혈청 VEGF 농도와의 상관 관계를 비교 분석하였다. 결 과 : 무호흡-저호흡지수와 혈청 sICAM-1 농도 사이에는 유의한 상관관계가 없었지만(r=0.27, P>0.05), 무호흡-저호흡지수와 혈청 VEGF 농도는 유의한 상관관계가 있었다(r=0.50, P<0.01). 무호흡지수와 혈청 sICAM-1 농도는 다소 유의한 상관관계가 있었으며(r=0.31, P<0.01) 무호흡지수와 혈청 VEGF 농도 사이에는 유의한 상관관계가 있었다(r=0.45, P<0.01). 결 론 : 폐쇄성 수면 무호흡 혹은 저호흡은 혈청내 sICAM-1 및 VEGF 농도를 증가시키는 것을 알 수 있었으며, 이러한 사이토카인의 발현 증가는 폐쇄성 수면무호흡 증군 환자에서 심혈관질환의 발생에 관련이 있을 것으로 추측된다.