• BMB Reports
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• 제29권1호
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• pp.38-44
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• 1996

Taq DNA polymerase from Thermus aquaticus has been shown to be very useful in the polymerase chain reaction method, which is being used for amplifying DNA. Not only does Taq DNA polymerase have high commercial value commercial value for the polymerase chain reaction application, but it is also important in studying DNA replication, because it is apparently an homologue to E. coli DNA polymerase I, which has long been used for DNA replication study (Lawyer et ai., 1993). The crystal structure determination of Taq DNA polymerase was initiated. An X-ray diffraction pattern breaks down a crystal structure into discrete sine waves in a Fourier series. The original shape of a crystal object in terms of electron density may be represented as the sum of those sine waves with varying amplitudes and phases in three dimensions. The molecular replacement method was initially employed to provide phase information for the structure of Taq DNA polymerase. The rotation search using the program MERLOT resulted in a solution peak with 5.4 r.m.s. PC-refinement of the X-PLOR program verified the result and also optimized the orientation angles. Next, the translation search using the X-PLOR program resulted in a unique solution peak with 7.35 r.m.s. In addition, the translation search indicated $P3_121$ to be the true space group out of two possible ones. The phase information from the molecular replacement was useful in the MIR phasing experiment.

• 경영과학
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• 제31권1호
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• pp.17-26
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• 2014

This study presents a new real estate value analysis model considering the changes in the population structure. We propose a new model that takes advantage of the binomial option model one of the techniques of real options and considers the changes in the population structure. The real estate market price data of Seoul city from year 2001 to 2012 were extracted and the correlation analysis between real estate prices and changes in the population structure was performed. The result shows that they have positive correlation with one year time lag. The coefficient between the real estate prices and demographic changes was estimated using the OLS analysis and included in the traditional binomial option model to calculate the value of the property. It is assumed for the future price prediction that real estate invested in Seoul in January, 2013 will be sold within five years. Analysis result shows that the values of real estate in September of 2013 were predicted as 583.5 million won in the new model and as 582.4 million won in the traditional model. This reflects that the new model considering the change of population change gives better realistic performance than the traditional one.

• 한국육종학회지
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• 제42권1호
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• pp.11-22
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• 2010

The population structure of a domesticated species is influenced by the natural history of the populations of its pre-domesticated ancestors, as well as by the breeding system and complexity of breeding practices implemented by humans. In the genetic and population structure analysis of 122 South Asia collections using 29 simple sequence repeat (SSR) markers, 362 alleles were detected, with an average of 12.5 per locus. The average expected heterozygosity and polymorphism information content (PIC) for each SSR locus were 0.74 and 0.72,respectively. The model-based structure analysis revealed the presence of three clusters with the 91.8% (shared > 75%) membership, with 8.2% showing admixture. The genetic distances of Clusters 1-3 were 0.55, 0.56, and 0.68, respectively. Polymorphic information content followed the same trend (Cluster 3 had the highest value and Cluster 1 had smallest value), with genetic distances for each cluster of 0.52, 0.52, and 0.65, respectively. This result could be used for supporting rice breeding programs in South Asia countries.

• The Journal of Asian Finance, Economics and Business
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• 제8권9호
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• pp.23-33
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• 2021

The main objective of this research is to examine the effect of organizational culture, environmental uncertainty, and manager's personnel value on environmental disclosure through the environmental organizational structure of manufacturing companies on the Indonesia Stock Exchange. This research uses the structuration and contingency theory. The sample in this study focused on the level of heads or managers or directors of manufacturing companies listed on the Indonesia Stock Exchange. The research data was obtained through an online questionnaire distributed to heads or managers. The total sample of this study is 161 manufacturing companies. The data comprising of 64 respondents was completed and can be processed. Empirical testing used Structural Equation Modeling (SEM) through Partial Least Square (PLS). The result shows that environmental uncertainty and management personnel value have a positive effect on the environmental organizational structure, as well as the environmental organizational structure has a positive effect on the environmental disclosure. However, organizational culture has no effect on the environmental organizational structure. This research can provide benefits for manufacturing companies. The limitation include the low level of response from the respondents. Also the results cannot be generalized due to its specific focus on the manufacturing companies.

• The Journal of Advanced Prosthodontics
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• 제3권1호
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• pp.10-15
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• 2011

PURPOSE. This study investigated the influence of bone quality and surgical technique on the implant stability quotient (ISQ) value. In addition, the influence of interfacial bone quality, directly surrounding the implant fixture, on the resonance frequency of the structure was also evaluated by the finite element analysis. MATERIALS AND METHODS. Two different types of bone (type 1 and type 2) were extracted and trimmed from pig rib bone. In each type of bone, the same implants were installed in three different ways: (1) Compaction, (2) Self-tapping, and (3) Tapping. The ISQ value was measured and analyzed to evaluate the influence of bone quality and surgical technique on the implant primary stability. For finite element analysis, a three dimensional implant fixture-bone structure was designed and the fundamental resonance frequency of the structure was measured with three different density of interfacial bone surrounding the implant fixture. RESULTS. In each group, the ISQ values were higher in type 1 bone than those in type 2 bone. Among three different insertion methods, the Tapping group showed the lowest ISQ value in both type 1 and type 2 bones. In both bone types, the Compaction groups showed slightly higher mean ISQ values than the Self-tapping groups, but the differences were not statistically significant. Increased interfacial bone density raised the resonance frequency value in the finite element analysis. CONCLUSION. Both bone quality and surgical technique have influence on the implant primary stability, and resonance frequency has a positive relation with the density of implant fixture-surrounding bone.

• 한국정보과학회논문지:소프트웨어및응용
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• 제35권7호
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• pp.452-461
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• 2008

바이너리 코드의 차이점 분석은 보안 패치와 같은 매우 유사한 두 프로그램 사이의 차이점을 구별해 주는 방법이다. 이전의 연구에서는 분석을 위하여 프로그램의 구조 또는 명령어의 세부 사항만을 각각 이용하였다. 프로그램의 구조를 이용하는 차이점 분석 방법은 제어 흐름의 변화는 잘 탐지해 낼 수 있지만, 버퍼 크기 변화와 같은 상수 값의 변화는 잘 찾아낼 수 없다. 명령어 기반의 차이점 분석 방법은 세부적인 값의 변화는 발견할 수 있으나 명령어 재배치와 같은 컴파일러에 의해 생성되는 불필요한 차이점을 결과로 낸다는 단점이 있다. 이 연구에서는 프로그램 구조를 이용한 비교 분석 방법에 상수 값의 변화를 함께 추적할 수 있는 방법을 제안하고 바이너리 차이점 분석 도구를 구현하였다. 구현된 도구는 윈도 보안 업데이트를 이용하여 평가하였다. 실험 결과 제안된 방법은 구조적인 차이점 분석과 같이 빠른 속도로 구조적인 변화를 찾아낼 뿐 아니라 상수 값의 변화까지 추적할 수 있다는 것을 보였다.

• 한국농촌건축학회논문집
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• 제13권1호
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• pp.37-44
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• 2011

The maintenance works for brick-structured buildings are a new field in Korea, and practical cases are yet inadequate so that such works may cause adverse effects of damaging the buildings after all. Therefore, this study has extracted a preservation technology believed to be most desirable in minimizing the damage to the original state of the buildings and preserving the value as the cultural assets through maintenance work details from 1986 to 2010 regarding brick-structured buildings designated as cultural properties. Firstly, a brick replacement method of using the brick used at the time of construction is efficient in replacement and repair of brick material for preserving value of cultural assets and minimizing damage of the original form. Secondly, use of lime mortar through material analysis is effective in repair of masonry joint and mortar but it is not used often due to high experimental cost. Finally, reinforcement of structure using a form for a building with severe damage is most efficient when considering additional problems. However, damage on the original form of a building can be minimized and value of a building can be preserved only when consideration on sufficient case analysis, materials to be used, and conditions of a building is supported.

• 한국가구학회지
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• 제21권2호
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• pp.157-166
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• 2010

Furniture in the modern living environment, inclusive the importance of its practical value, is a plastic element of indoor space, and its artistic value also holds an important position. Moreover, emotional design based on the emotional engineering in a structural change of modern society such as urbanization, small family, aging society is proposed as an important keyword in the modern design. Namely, furniture as an component of modern residential space has been advanced as a human-oriented environmental element considering people's emotional and mental value to the functional satisfaction and artistic and emotional satisfaction. Furniture is a living tool that is much contacted to people, which affects highly on people's body and mind. This means that people's volition action can be naturally induced by furniture design, and that furniture can display a role as an active tool of means to make people's interpersonal communication and interchange. Namely, I think furniture design of emotional interchange that understands furniture user's pattern behavior and pattern, and observes furniture form and structure and functionality on users' relationship affecting on people's emotional stability and interpersonal interchange of emotion, as an indispensable element necessary for producing more human and prosperous environment of life.

• 전자공학회논문지SC
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• 제46권3호
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• pp.8-14
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• 2009

본 논문은 성능 향상을 위하여 IMC 제어 구조를 갖는 PID 제어기 설계를 제안했다. 내부 모델은 최종값 정리와 유전자 알고리즘을 이용하여 2차의 지연시간을 갖는 모델로 동정 하였다. 그리고 제어기 파라미터 값은 성능지수 (IAE, ITAE)값이 최소가 되도록 내부 모델과 수치적 계산에 의해서 자동 동조된다. 시뮬레이션을 통하여 다양한 공정에 대하여 본 논문에서 새롭게 제안된 방법이 기존의 방법보다 우수함을 확인 할 수 있었다.

• 한국기계가공학회지
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• 제19권1호
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• pp.100-107
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• 2020

As demand for high value-added products with hard materials increases, the line center is used for producing high value-added products in many industries such as aerospace, automobile fields. The line center is a key device for smart factory automation that can improve the production efficiency and the productivity. Therefore, the development of a mill-turn line center is necessary to produce high value-added products with complex shapes flexibly. In the mill-turn process, a milling process and a turning process are combined. In particular, the turning process needs to increase the rigidity of the spindle. The purpose of this study is to analyze the thermal-structural stability through thermo-structural coupled analysis for a mill-turn spindle with a curvic coupling. The maximum temperature and thermal stability of the spindle were analyzed by thermal distribution. In addition, the thermal deformation and thermal-structural stability of the spindle were analyzed through thermo-structural coupled analysis.