• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.4019-4023
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• 2015

Background: Breast cancer is the most frequently occurring cancer in women and the most common cause of cancer death worldwide. Materials and Methods: A cross-sectional study was carried out among 792 female undergraduate students in public universities in Klang Valley, Malaysia, from January to April 2011. Data were collected using a validated questionnaire developed for this study. Results: The mean age of respondents was $21.7{\pm}1.2$ years. Most of them were single (96.8%), Malay (91.9%) and 150 (19.6%) claimed they had practiced BSE. There was a significant differences between performers and non-performers correlated to age, marital status, check breast by doctor, and being trained about BSE. Performers had lower mean scores for perceived barriers and susceptibility and higher mean score for confidence. Stepwise logistic regression analysis yielded four significant predictor variables. Conclusions: Overall our findings indicate that the practice of BSE while perceived as being important is not frequently practiced among female in Malaysia. Targeted education should be implemented to improve early detection of breast cancer.

• Proceedings of the Korean Environmental Health Society Conference
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• 2003.06a
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• pp.26-26
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• 2003

During the Viet Nam war, A Luoi located in Thua Thien Hue Province was heavily sprayed herbicides by the Ranch Hand Operation of U.S.A force (549.274 gallons). After 30 years of knocking the operation off, Dioxin has still contaminated on environment and human body in A Luoi valley. The results of the study show that there is an epidemiological relationship between AO/Dioxin exposure and increasing rate of reproductive anomalies and birth defects (the rate of reproductive anomalies including congenital deformities after the war during 10-year and 25-year is higher than that before the war from 1.5 to 4 times). The study found that the highest rate of reproductive anomalies is spontaneous abortion. The average is premature death and congenital deformities, and the lowest rate is dead foetus and hydratidiform mole. The results of the primary assessment suggested that Dioxin transport from environment to human body through the food chain exposed by Dioxin such as fish, chicken, duck. A mitigation plan for residual dioxin contamination from Agent Orange Hervicides is requeste indispensable to inhabitants in Aluoi District.

• Biomolecules & Therapeutics
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• v.20 no.6
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• pp.538-543
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• 2012

The Maillard Reaction Products (MRPs) are chemical compounds which have been known to be effective in chemoprevention. Death receptors (DR) play a central role in directing apoptosis in several cancer cells. In our previous study, we demonstrated that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal, a MRP product, inhibited human colon cancer cell growth by inducing apoptosis via nuclear factor-${\kappa}B$ (NF-${\kappa}B$) inactivation and $G_2$/M phase cell cycle arrest. In this study, (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate, a new (E)-2,4-bis(p-hydroxyphenyl)-2-butenal derivative, was synthesized to improve their solubility and stability in water and then evaluated against NCI-H460 and A549 human lung cancer cells. (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate reduced the viability in both cell lines in a time and dose-dependent manner. We also found that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate increased apoptotic cell death through the upregulation of the expression of death receptor (DR)-3 and DR6 in both lung cancer cell lines. In addition to this, the transfection of DR3 siRNA diminished the growth inhibitory and apoptosis inducing effect of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate on lung cancer cells, however these effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate was not changed by DR6 siRNA. These results indicated that (E)-2,4-bis(p-hydroxyphenyl)-2-butenal diacetate inhibits human lung cancer cell growth via increasing apoptotic cell death by upregulation of the expression of DR3.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.8 no.4
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• pp.95-109
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• 2013

The practices and processes of HRM (Human Resource Management) for university faculty in Korea depend heavily on assessment of research and teaching rather than the UIC (University-Industry Cooperation) performance. In this regard, HRM of Korean universities is said to be far distant from UIC. Although policy initiatives by the Korean government, notably the MoE (Ministry of Education) have implemented in most universities, the desirable level of UIC could not be achieved yet. Moreover, the very notion of 'university' in Korea is much more to do with 'pure' education and research institution than with 'applied' and 'vocational' purpose. Considering upon HRM practices and organizational culture, for enhancing UIC in Korea, the government's policy should be linked to alter deep-rooted university culture. So the aims of the research are to describe the current state of HRM in Korean and foreign universities; to find out the critical factors of UIC in Korean universities; to analyze the gaps between university research and industrial commercialization based on a conceptual framework, the 'valley of the death'; and to recommend HRM policies fostering UIC for the MoE. For achieving these objectives, we deploy multiple methodologies, namely, in-depth interview, literature survey, and statistical data analysis with regard to UIC. Analyzing the data we have collected, the present research sheds light on all aspects of HRM processes and UICs. And the main policy implication is restricted to the Korean universities, even if we have collected and analyzed foreign universities, notably universities in the USA. The research findings are mainly two folds. Firstly, the HRM practices among Korean universities are very similar due to the legally institutionalized framework and the government's regulations. Secondly, the difficulties of UIC can be explained by notion of the 'valley of death' ways in which both parties of university and industry are looking for different purposes and directions. In order to overcome the gap in the valley of death, the HRM policy is better to be considered as leverage. Finally, the policy recommendations are as follows. Firstly, various kinds of UIC programs are able to enhance the performances of not only UIC, but also education and research outcome. Secondly, fostering organizational climate and culture for UIC, employing various UIC programs, and hiring industry-experienced faculty are all very important for enhancing the high performance of university. We recommend the HRM policies fostering UIC by means of indirect way rather than funding directly for university. The HRM policy of indirect support is more likely to have long-term effectiveness while the government's direct intervention to UIC will have likely short-term effectiveness as the previous policy initiatives have shown. The MEST's policy means of indirect support might vary from financial incentives to the universities practicing HRM for UIC voluntarily, to information disclosure for UIC. The benefits of the present research can be found in suggesting HRM policy for UIC, highlighting the significance of industry-experienced faculty for UIC, and providing statistical analysis and evidences of UIC in Korean universities.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.11 no.4
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• pp.139-148
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• 2016

The importance of technology commercialization is being emphasized more and more, but high technology excellence does not always lead to a successful business. In addition, companies that invest heavily in basic research and technology development are also not always able to guarantee high profits. This is due to the technical problems when present in step research and development levels are difficult to commercialize. And the market will not work rationally is also the cause of the problem. Therefore, to effectively utilize the resources necessary to ensure such partners to build alliances and cooperation with external funding or manpower is crucial to commercialize the research results of basic science successfully. In previous studies, it has been made many studies in accordance with the approach to the technology (e.g. Research and Development, Management of Technology, Technology Innovation, etc.). But the study of technology commercialization point of view is not being done much. This study should explores the available business required, or realized in the process of researching the basic science and trying to understand the imperfections of the market through the property of technology (tacit knowledge, objectified value of technology and the information asymmetry between innovation subjects, etc.). In addition, this paper, we try to focus on a strategic approach to the role of International Science Business Belt (ISBB) with success in science and technology business as appropriate countermeasures about breaking the 'Valley of Death.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.15 no.5
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• pp.405-412
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• 2022

This paper studies the method of estimating power loss and classifying the factors for improving the power generation efficiency through O&M. It is installed under various climatic conditions worldwide, operational and maintenance technologies suitable for the characteristics of the installation location are required. Existing studies related to solar power generation efficiency have been actively quantifying the impact on short-term losses by environmental factors such as high temperature, dust accumulation, precipitation, humidity, and wind speed, but analysis of the overall impact from a long-term operation perspective is limited. In this study, the potential for efficiency improvement was analyzed by re-establishing a loss classification system according to the power flow of solar power to derive a comprehensive efficiency model for long-term operation and estimating power loss through a case study for each region where climate conditions are classified. As a result of the analysis, the average annual potential for improving soiling loss was 26.9%, Death Valley 7.2%, and Seoul 3.8%. Aging losses was 6.6% in the 20th year as a cumulative. The average annual potential due to temperature loss was 2.9 % for Doha, 1.9% for Death Valley, and 0.2% for Seoul.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.11 no.2
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• pp.49-62
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• 2016

Technology-based start-ups have great economic ripple effect such as economic growth and job creation. Therefore, a strategic approach is required in order for such start-ups to continuously grow. However, many technology-based start-ups do not survive the Death-Valley and are being eliminated from the market. This is an empirical study on influencing variables that have impact on their performance. This study presents growth intention and influencing variables that have impact on performance (financial performance, technological performance) based on previous research on technology-based start-up. Also, this study examines the relationship between entrepreneurial competence, team commitment and growth intention, and finds the effect of controlling business-network. Structural equation modeling was performed in order to test the research hypothesis. Survey was conducted on the firms that have been certified by Youth Startup Academy of Small and Medium Business Corporation. A total of 306 samples were collected from the survey. An empirical test was conducted on the research hypothesis using SPSS 21.0 and Amos 22.0. The result of hypothesis test shows that growth intention has positive influence on both financial and technological performance, and entrepreneurial competence (technological competence, strategic management competence, creative competence and team commitment) has positive influence on growth intention. Also, the research proved that business-network has regulation effect between human resource trait and growth intention. The result of our study will provide practical insight to future start-ups for continuous growth and successful running of their firm.

• STI Policy Review
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• v.4 no.1
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• pp.94-118
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• 2013

Innovation plays a large role in green growth. While it is a widely accepted view that, without innovation, it would be very difficult and costly to address major environmental issues, innovation itself tends to be constrained by limited access to eco-financing and is inherently risky, often requiring a long-term horizon. Although global consensus is more or less established as to the urgency and necessity of accelerating green innovation, the quality and quantity of financing in this area is largely insufficient, with increasing funding gaps in many countries. A new financial mechanism is urgently needed in order to re-orient financial flow and enable innovators to overcome the valleys of death that occur throughout the innovation cycle. A number of different modalities exist in financing the commercialisation of eco-innovation. Existing mechanisms have not been as successful as expected, revealing critical limits to furthering certain types of projects that are essential for economic and environmental progress. Experts' estimations have shown that the funding gap will widen in the coming years as demand for clean energy and green infrastructure rises, and as green technologies and innovation develop faster than the market for it can develop. Against this backdrop, the main purpose of this research is threefold: to identify issues and problems regarding current means of funding for eco-innovation and green projects; to provide insight into securing longterm green financing by looking at European cases; and ultimately to suggest policy implications for designing and implementing eco-specific financial instruments, focusing on governments' roles in sustainable financing for eco-innovation. This study analyses different models of financing mechanisms, a mix of public and private funds, in view of suggesting conditions for the sustainable financing of green projects, especially for large-scale high-risk projects. Based on the findings from the analyses of mechanisms and the shortcomings of the existing funding modalities, this study ultimately suggests policy implications for effectively supporting the commercialisation of eco-innovation.

• The Korean Journal of Quaternary Research
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• v.18 no.2 s.23
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• pp.67-73
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• 2004

Dissected erosional surfaces are widely distributed in the western part of Korea (e.g. Icheon, Chungju, Jecheon, Seosan). The deposits with thickness of less than 2m occur on the smooth bedrock surface are composed of poorly sorted subangular gravels with less than 20cm diameter. However, only weathered mantle of granites without the gravel layer are observed at some outcrops. The results of grain size analysis of deposits of Icheon district revealed that the characteristic of the gain size distribution is very similar with the results of sheetflood deposits presented by Blair (1999) in the Death Valley. Loess layer with buried soil layers of MIS7 covers the sheetflood deposits. The loess layer implies that the sheetflood deposits occurred before MIS7 based on the typical Loess sequences presented by Naruse et al.(2003). On the other hand, the climate of Korean Peninsula in MIS2 was very dry and cold (Yoon and Hwnag, 2003) by pollen analysis. This is because Yellow Sea was completely emerged during the MIS2(e.g. Sau\ito, 1998). So, it is thought that the climate in Korean Peninsula of not only MIS2 but also other glacial ages such as MIS8 was similar with present Mongolian climates. Tanaka et al.(2005) pointed out that Hortonian overlandflow occurs in grass vegetated granite basin in Mongolia. Therefore, dissected piedmont gentle slopes in the western Korea were possibly formed by sheetflood erosion during probably MIS8 as pediment widely distributed in Mongolia.

• Journal of Information Technology Services
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• v.16 no.4
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• pp.47-64
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• 2017

Three years after establishment, companies are said to face a period of risk called the "valley of death." To start a venture company and make it sustainable, the chance of failure must be minimized. According to an in-depth assessment report on special taxation in 2015, the one-year survival rate of Korean companies was about 60 percent and the five-year survival rate about 30%. These rates are low compared to those of major OECD member countries. Worse, such rates in Korea are decreasing year by year. The purpose of this study is to classify the success factors behind venture companies into human capital, social capital and financial capital, and verify through empirical analysis the factors influencing the success of venture companies based on the mediating roles of capability of the startup team and that for innovation. To find the success factors behind venture companies, this study first examined the theories derived from previous studies. SPSS 21 was used as the study method, while descriptive statistics, exploratory factor analysis and CMB test were conducted. In addition, SmartPLS 2 was used for confirmatory factor analysis, hypothesis test, mediation effect. The results of this study can help efforts toward job creation and economic revitalization pursued by the creative economy policy of the incumbent Korean administration. They can also be used as the cornerstone for venture companies in their pursuit of success.