• Proceedings of the Korean Society of Plant Biotechnology Conference
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• 2005.11a
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• pp.315-315
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• 2005

• 한국약용작물학회:학술대회논문집
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• 2010.10a
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• pp.256-257
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• 2010

• Korean Journal of Environmental Biology
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• v.36 no.4
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• pp.659-664
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• 2018

In this study, two essential oils (EOs) extracted from Aleriana fauriei and Alpinia galangal were formulated as an emulsifiable concentrate (EC) and a granule. In the evaluation of their acute toxicity on fishes, Cyprinus carpio adults were used and the toxicities were determined in a static condition. The formulations were prepared from the essential oil extracted by three different methods namely steam distillation (SD), solvent extraction (SE) and supercritical fluid extraction (SFE). The acute toxicities were calculated using $LC_{50}$ values. Among EOs, only the EO extracted by solvent showed acute toxicities on carps. Some of the EC, EOs of Aleriana fauriei did not exhibit toxicity, while EOs from Alpinia galangal showed potent acute toxicities on carps. Among the granules, granules formulated with Aleriana fauriei EO extracted by SD method and Alpinia galangal EO extracted by SFE method showed acute toxicities on fishes. Nevertheless, $LC_{50}$ of ECs and granules formulated with all types of EOs in this study was higher than the fish toxicity level III for pesticides suggested by Korea Rural Development Administration. Furthermore, cytochrome P450 1A and glutathione S-transferase were confirmed as biomarkers in carps in response to the exposure to Alpinia galangal EO extracted by SD and SFE method, tracking Alpinia galangal EO in the aquatic environment.

• Korean Journal of Pharmacognosy
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• v.5 no.1
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• pp.1-6
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• 1974

Essential oils were separated by steam distillation from the roots of four species of the genus Valeriana and subjected to gas chromatography to screen monoterpenic hydrocarbons and related components. The amounts of the common components were contained in the following order: camphene, ${\alpha}-pinene$, bornyl-, myrtenyl isovalerate, myrtenylacetate and ${\beta}-pinene$, and small amounts of terpineol and terpinylacetate were also contained. Of the four species, the root of Valeriana fauriei $B_{RIQUET}$ var. dasycarpa $H_{ARA}$ contained the largest amounts of these components and the root of V. dageletiana $N_{AKAI}$ ex $M_{AEKAWA}$ the least. Since the root of V. dageletiana contained for less amounts of pinene, camphene and bornylacetate and none of dipentene and terpineol, this plant appears to be distinguished from the other three species.

• Korean Journal of Medicinal Crop Science
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• v.24 no.5
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• pp.341-350
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• 2016

Background: Prenatal exposure to infectious and/or inflammatory insults can increase the risk of developing neuropsychiatric disorder such as bipolar disorder, autism, and schizophrenia later in life. We investigated whether Valeriana fauriei (VF) treatment alleviates prepulse inhibition (PPI) deficits and social interaction impairment induced by maternal immune activation (MIA). Methods and Results: Pregnant mice were exposed to polyriboinosinic-polyribocytidilic acid (5 mg/kg, viral infection mimic) on gestational day 9. The adolescent offspring received daily oral treatment with VF (100 mg/kg) and injections of clozapine (5 mg/kg) for 30 days starting on the postnatal day 35. The effects of VF extract treatment on behavioral activity impairment and protein expression were investigated using the PPI analysis, forced swim test (FST), open field test (OFT), social interaction test (SIT), and immunohistochemistry. The MIA-induced offspring showed deficits in the PPI, FST, OFT, and SIT compared to their non MIA-induced counterparts. Treatment with the VF extract significantly recovered the sensorimotor gating deficits and partially recovered the aggressive behavior observed in the SIT. The VF extract also reversed the downregulation of protein expression induced by MIA in the medial prefrontal cortex. Conclusions: Our results provide initial evidence of the fact that the VF extract could reverse MIA-induced behavioral impairment and prevent neurodevelopmental disorders such as schizophrenia.

• Korean Journal of Medicinal Crop Science
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• v.4 no.1
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• pp.7-11
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• 1996

This study was conducted to know the effects of light intensity and temperature on growth of V. fauriei plants. Photosynthesis of V. fauriei had highly significant relations to light intensity and temperature in a quadratic regression model, from which the optimum light intensity and temperature for the plant growth were estimated to be 40,000lux and $17.7^{\circ}C.$ Root was produced less by shading at Jinbu where is located in alpine region, but root yield is increased by shading at Umsong where is located in plane region. Roots were produced more in Jinbu than in Umsong. A highly significant quadratic regression was noted between temperature and leaf width or root weight of V. fauriei. It was estimated from the regression equation that the optimum temperature for root growth was $20.3^{\circ}C.$

• 농업기술회보
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• v.50 no.3
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• pp.26-27
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• 2013

약용식물 중에는 뿌리에서 쥐 오줌 냄새와 비슷한 특이한 향이 있어 붙여진 이름의 '쥐오줌풀(Valeriana fauriei Briquet, 한약재명 길초근)'이라는 식물이 있다. 천연 신경안정제로 효능이 매우 다양하게 밝혀져 있어 유럽, 미국, 호주 등 전세계적으로 차, 음료, 정제, 분말캡슐, 액상류 등 건강식품 원료로 널리 이용한다. 농촌진흥청에서는 2010년부터 2012년까지 3년 동안 '쥐오줌풀'의 대량번식방법과 직파 또는 육묘이식방법, 심기 적당한 간격과 비료랑, 재배적지 등의 재배기술을 개발하여 농가에서 대량생산할 수 있도록 하였다.

• 한국약용작물학회:학술대회논문집
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• 2012.05a
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• pp.81-82
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• 2012

• 한국약용작물학회:학술대회논문집
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• 2012.05a
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• pp.23-24
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• 2012

• KOREAN JOURNAL OF CROP SCIENCE
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• v.42 no.1
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• pp.22-32
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• 1997

This experiment was conducted to obtain information for the cultivation of Korean valerian(Valeriana lauriei var. dasycarpa Hara) which will be useful for medicinal and aromatic resources. The effect of different temperature conditions, light intensities and soil water conditions on growth, yield and component of essential oil of V. fauriei were measured at the Dankook University, Cheonan, and a study on the shading treatment was at Umsung, Chungchongbukdo, and Jinbu, Kangwondo, in 1995. V. laudei was planted at five different temperature conditions, 10, 15, 20, 25 and 3$0^{\circ}C$, eight light intensity conditions, 1, 000, 2, 500, 5, 000, 20, 000, 30, 000, 40, 000, 50, 000 and 60, 000lux, six soil water contents, 30, 45, 55, 70, 80 and 90％ of the saturated soil, during growth stage. Shading treatment was three conditions, 0, 25 and 50％, during the daytime in field conditions. Photosynthesis had a highly significant relationship with temperature conditions in a quadratic regression model, from which the temperature for the plant growth was estimated to be 17.7$^{\circ}C$. A highly significant quadratic regression was noted between temperature and leaf width or root weight of V. fauriei. It was estimated from the regression equation that the optimum temperature for root growth was 20.3$^{\circ}C$. The content of essential oil and extract rate of root was the highest in the 15~2$0^{\circ}C$. Photosynthesis also was significantly affected by light intensity in a quadratic regression model, from which the optimum light intensity for the growth was estimated to be 40, 000lux. Root yield was more produced in Jinbu than that of in Umsung. The root yield was increased by the shading treatment in Umsung, whereas it was decreased by the shading treatment in Jinbu. The content of essential oil was not affected by the shading treatment of plants during the cultivation, while the compositions of components of essential oil were related to the growing locations. As soil water content was higher, the growth and content of root extract were increased. The optimum soil moisture for the growth of V. fauriei was 80~90％ of the saturated soil. In summary, the results indicated that the growth, yield and component of essential oil in V. fauriei were affected by environmental factors as well as soil moisture.