• 대한치과교정학회지
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• 제53권5호
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• pp.336-342
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• 2023

Objective: To determine whether the gonial angle on digital panoramic radiographs is associated with vitamin D receptor (VDR) Taql polymorphism. Methods: Genomic DNA samples were collected from the buccal mucosa of patients aged 26-43 years. TaqMan assay for single nucleotide polymorphism genotyping was used to detect the genotype of Taql polymorphism. The gonial angle was measured bilaterally on panoramic radiography. The normal gonial angle was fixed as 121.8°, and it represented the cutoff value for the high gonial angle (HGA) and low gonial angle (LGA) groups. Various genetic models were analyzed, namely dominant (homozygous [AA] vs. heterozygous [AG] + polymorphic [GG]), recessive (AA + AG vs. GG), and additive (AA + GG vs. AG), using the chi-squared test. Results: The reliability of the gonial angle measurement was analyzed using a random sample (26%) of the tests, with the intra-examiner correlation showing an intra-class correlation coefficient of 0.99. The frequencies of the AA, AG, and GG genotypes of rs731236 polymorphism were 40.5%, 41.9%, and 17.6% in the HGA group and 21.8%, 51.0%, and 27.2% in the LGA group, respectively (P = 0.042). A statistically significant difference was observed in the allele frequencies between the two groups (P = 0.011). Moreover, a significant correlation was observed in the dominant genetic model. Conclusions: Taql polymorphism in the VDR gene plays a critical role in the vertical growth of the mandible and decreased gonial angle.

• 대한치과교정학회지
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• 제54권5호
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• pp.284-302
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• 2024

Objective: External apical root resorption (EARR) is characterized by permanent loss of dental structure at the root apex. This study aimed to systematically review gene polymorphisms associated with EARR in orthodontic patients. Methods: Electronic database searches were performed across several databases. Results: This systematic review included 21 studies. Outcome measures were based on tooth dimensions observed on radiographs obtained before and after treatment. Polymorphisms in the following genes were genotyped using polymerase chain reaction-restriction fragment length polymorphism analysis: purinergic-receptor-P2X, ligand-gated ion channel 7 (P2RX7), caspase-1/interleukin-converting enzyme (CASP1/ICE), caspase-5 (CASP5), IL-1beta (IL1B), IL-1alpha (IL1A), interleukin-1 receptor antagonist gene (IL1RN), tissue non-specific alkaline phosphatase (TNSALP), tumor necrosis factor-alpha (TNFα), tumor necrosis factor receptor superfamily gene member 11a (TNFRSF11A), secreted phosphoprotein 1 (SPP1), tumor necrosis factor receptor superfamily gene member 11b (TNFRSF11B), interleukin 17A (IL17), interleukin 6 (IL6), receptor activator of nuclear factor-kappa B (RANK), osteoprotegerin (OPG), stromal antigen 2 (STAG2), vitamin D receptor (VDR), cytochrome P450 family 24 subfamily A member 1 (CYP24A1), cytochrome P450 family 27 subfamily B (CYP27B1), group-specific component (GC), and interleukin-1 receptor-associated kinases 1 (IRAK1). Conclusions: Almost all studies suggested that IL1 gene is associated with EARR. Additionally, P2RX7 may be an important factor contributing to the etiopathogenesis of EARR. TNFRSF11A, SPP1, IL1RN, IL6, TNFRSF11B, STAG2, VDR, IRAK1, IL-17, CASP1/ICE and CASP5 have been identified in isolated studies. Further observational studies are needed to better explain the association between these genes and EARR.

• 한국항해학회지
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• 제24권5호
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• pp.435-441
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• 2000

This paper deals with the development of RACOM(Radar Signal Detecting ＆ Processing Computer). RACOM is a radar display system specially designed for radar scan conversion, signal processing and PCI radar image display. RACOM contains two components； i )RSP(Radar Signal Processor) board which is a PCI based board for receiving video, trigger, heading & bearing signals from radar scanner ＆ tranceiver units and processing these signals to generate high resolution radar image, and ⅱ）Applications which perform ordinary radar display functions such as EBL, VRM and so on. Since RACOM is designed to meet a wide variety of specifications(type of output signal from tranceiver unit), to record radar images and to distribute those images in real time to everywhere in a networked environment, it can be applicable to AIS(Automatic Identification System) and VDR(Voyage Data Recorder).

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2014년도 춘계학술대회
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• pp.120-122
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• 2014

선박의 조타기 작동 신호를 AIS를 통하여 전달함으로써 상대선박의 변침의도를 신속히 파악하여 충돌위험을 피할 수 있는 선회조기감지시스템을 구현하고 실선실험을 통하여 그 실효성을 검증하였다. 또한, 실선실험을 통해 선박의 타각정보가 AIS를 통해 송 수신이 가능하다는 것을 확인하였으며, ECDIS에 표시된 타각정보는 주변선박의 충돌회피에 크게 기여할 것으로 판단된다. 선회조기감지시스템은 선박의 안전운항을 위한 정보 제공의 필요성, 선박 통항량 증가 및 고속화 등으로 인한 위험성 증대로 VTS관제의 역할이 더욱 중요시 되고 있는 상황에서 선박의 조타각이 표시된 해당 시스템을 활용할 경우 변침상황을 보다 신속히 파악할 수 있으므로 관제가 보다 쉬워질 것으로 예상된다. 또한, 선박의 침몰이나 VDR의 소실로 인한 해양사고 분석의 어려움도 AIS를 통한 조타신호가 저장된 해양안전종합정보시스템(GICOMS)의 분석을 통해 다소 해소될 것으로 판단된다.

• 선박안전
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• 통권27호
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• pp.25-36
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• 2009

Despite the development of the various navigational equipment, such as GPS, ARPA, ECDIS, AIS, VDR, and hull monitoring system, marine accidents are still a leading concern in shipping industry. For all accidents over the reporting period, approximately 60 to 80% of the accidents was involved in human error. It means that in each case, some events which were associated with human error initiated an accident, and those failures of human performance led to the failure to avoid an accident or mitigate it's consequences. However, the improvement and the effort on the maritime human error are still limited in an elementary step. The objective of this paper is to propose a modified Human Factors Analysis and Classification System (HFACS) model in order to analyse the collision accidents of tug-barge ship.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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• pp.52-53
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• 2001

In order for vitamin D to be active, it needs to get metabolized to 1, 25 (OH)$_2$D3. This active metabolite of vitamin D induces epithelial cell differentiation and is antiproliferative. However, at the efficacious concentration, the natural ligand for VDR is hypercalcemic and toxic to cells. Therefore, numerous analogs have been synthesized with the hope of generating a compound that retains vitamin D activity and is non-toxic.(omitted)

• 한국독성학회:학술대회논문집
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• 한국독성학회 2001년도 International Symposium on Effects of Edible Phytochemicals and Their Synthetic Derivatives on Carcinogenesis and Mutagenesis
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• pp.9-10
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• 2001

In order for vitamin D to be active, it needs to get metabolized to 1, 25 (OH)$_2$D3. This active metabolite of vitamin D induces epithelial cell differentiation and is antiproliferative. However, at the efficacious concentration, the natural ligand for VDR is hypercalcemic and toxic to cells. Therefore, numerous analogs have been synthesized with the hope of generating a compound that retains vitamin D activity and is non-toxic.(omitted)

• 한국항해학회지
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• 제22권1호
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• pp.31-49
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• 1998

The technology of navigational instruments and the profession of going to sea have entered a time of dramatic change. A paradigm shift is taking place which will eventually make the industry unrecognizable to those who first went to sea only twenty years ago. This change is most emphatically seen in three areas: Automatic Identification System(AIS), Electronic Chart Display and Information System(ECDIS), and Voyage Data Recoreder(VDR). In order to make these new instruments to be fitted on board commerical ships, international requirements for enhacing the safety of navigation on the world's waterways, the Chapter V of International Convention for the Safety of Life at sea, 1974 as ameded(hereinafter referred to as "SOLAS"), are being also changed.o changed.

• Journal of information and communication convergence engineering
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• 제5권3호
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• pp.289-294
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• 2007

With regard to a marine safety system, large vessels are generally loaded with INS (Integrated Navigation System). But although small and medium-sized ships are exposed to safety accidents in the sea, they are not carrying proper navigation devices and equipment. Accordingly, in order to develop INS for small and medium-sized ships(s-INS), an existing INS has newly been organized and integrated. Recently, more strict enforcement of INS-related regulations is expected at home and abroad, and the scope of their applications is being broadened. To keep up with this global trend that ships are being loaded with digital devices and equipment, this study has tried to develop s-INS, broadening its applications, and suggesting a future research plan.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2011년도 춘계학술대회
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• pp.87-88
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• 2011

다기능 선박조종시뮬레이터(Full-mission Shiphandling Simulator)를 이용한 사고분석 방법을 한국해양수산연수원이 보유한 DNV(Det Norske Veritas)선급에서 "Integrated Simulator System, NAUT AW(SIM), DYNPOS-AUT(SIM), HSC, TUG, ICE" Class로 인정하고, STCW 협약 Regulation I/12를 충족한 Russia TRANSAS사의 "NAVI-TRAINER PROFESSIONAL 5000 NTPRO 5000" Full-mission Shiphandling Simulator를 이용하여 시행하였다.