• 한국대기환경학회지
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• 제3권1호
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• pp.27-33
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• 1987

삼중수소 ($^{3}H$) 에 관한 환경 및 생물학상의 연구는 1950년대 중반부터 선진국에서 수행되오고 있다. 삼중소소에 대한 잠재적 노출의 경우 통상적 처리절차는 삼중수소의 신체부하량이라고 일컬어지는 이른바 신체내에 축적된 삼중수소의 양을 결정하기 위하여 삼중수소수로서 오줌속에 포함되는 삼중수소 방사능의 생리분석이다. 전신에 있어서 삼중수소의 최대허용신체부하량은 신체조직에 대하여 약 $30{\mu}Ci/{\ell}$ 이다. 생리분석에서 오줌속에 삼중수소를 검출하는데 가장 보편적인 조사준위(照射准尉)는 최대허용신체부하량의 1/10 이다. 이러한 생리분석 연구계획을 위해서는 소광보정(消光補正) 곡선을 그리는 것이 가장 우선적이다. 이것은 검뇨용 오줌의 색깔이 일정하지 않기 때문에 필요한 것이다. 이 경우에서 소광효과는 주로 오줌시료에 의한 섬광빛의 흡수에 기인된다. 소광보정곡선으로 판단된 공식은 통계적 근거에서 최소자승법에 의하여 Y (%) = 0.771 + 1.836 ${\tmes}10^{-4}$X(count)로 얻어졌다. 여기서 Y는 섬광계수 효율로서 약 12%에서 31% 범위의 값으로 나타났다. 본 논문에서는 삼중수소의 생물학적 반감기와 신체계통적으로 분포된 삼중수소에 적용되고 있는 정체(停滯) 공식에 관한 간략한 이론에 관하여 서술된다.

• 사상체질의학회지
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• 제21권3호
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• pp.216-222
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• 2009

1. Objectives: This case study described a process of the patient diagnosed as acute hepatitis A treated by medication based on the Sasang Constitutional Medicine and acupuctural theraphy and obtained improved effects about several symptoms. 2. Methods: We diagnosed the male patient with acute hepatitis A as Tae-Eumin Exterior-Cold-Disease by the Cold in the Esophagus, and administered Mahwangbalpyo-tang and Handayeolso-tang according to clinical progress. And we evaluated the results by liver function test(LFT; AST, ALT, $\gamma$-GTP ), total bilirubin level and the visual analog scale(VAS) of symptoms. 3. Results and Conclusion: Almost symptoms (except for jaundice) at the time of admission were disappeared, and also jaundice (estimated by color of scleras and color of urine) was alleviated. Also level of AST, ALT, $\gamma$-GTP and total bilirubin decreased in laboratory test. We obtained positive effects to the therapy but we considered necessities of further comparative studies with control group.

• 한국임상수의학회지
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• 제8권1호
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• pp.71-80
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• 1991

Clinical signs, serum chemical values and histological findings of hepatic tissue after partial and complete obstruction of common bile duct in Korean goats were investigated. Abnormal clinical signs were not observed in partial obstruction of common bile duct, but in complete obstruction clinical signs such as jaundice, urine color change, were observed. Serum total bilirubin, total cholesterol, aspartate aminotransferase, sorbitol dehydrogenase, gamma glutamyltranspeptidase, and total protein values increased on the 1-4th day and then gradually decreased to normal level in partial obstruction. However, they tend to increase persistently by the 24th day in complete obstruction of common bileduct. Histologic features of hepatic tissue in partial obstruction were not changed as compared with normal hepatic tissue. On the other hand, in complete obstruction of common bite duct there were moderate bile duct proliferation in a portal area, rupture of bile canaliculi, phagocytosis of bile pigment by Kupffer cells, periportal fibrosis, intrahepatic bile stasis and hepatic cell necrosis.

• 혜화의학회지
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• 제9권1호
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• pp.409-421
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• 2000

According to The Comparative study on the IgA Nephropathy and hematuria, the results were as follows. 1. IgA nephropathy is included in category of the hematuria the part in deficiency of liver-kidney and damp-heat in oriental medicine. 2. The symptoms of hematuia is changes in color of urine-bloody, dark brown, or rusty colored-without pain in oriental medicine. 3. It is occured IgA nephropathy due to vacuity exhaustion, fidgetiness, internal damage, imfection. 4. For the medical prescriptions due to IgA nephropathy are used Sogyeeumja, $Dayebunch\check{o}ngeum$(大分淸飮), Dangguieum(當歸飮), $Ch\check{o}ngjangtang$(淸腸湯), Silyungtang(柴岺湯), Kamisagunjatang(加味四君子湯) as hematuria of symtom of IgA nephropathy.

• 한국환경보건학회지
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• 제41권4호
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• pp.268-276
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• 2015

Objectives: According to the 2007 Korea National Environmental Health Survey (KNEHS), some areas in the Gyeongsang Provinces showed very high blood mercury levels in adults. We conducted this project to investigate any related health effects in children due to mercury levels in these areas. Methods: In total, 1,097 students between grades 3 and 6 at 19 elementary schools were recruited from four areas with high mercury exposure as identified by the KNEHS. Total mercury levels in biological samples were compared with health check-ups performed on the schoolchildren. Biological monitoring, supported by questionnaires, a computerized neurobehavioral test, a posturography test and a personality test, were applied. Results: Triglycerides showed a significant relation with mercury in blood, urine and hair. Total mercury concentrations were divided into two groups: upper and lower concentration groups based on the median value. In the computerized neurobehavioral test, the upper blood mercury group showed a greater reaction time for color-word vigilance (p<0.05). In the posturography test, the intensity value of the tremor test showd high significant relations with mercury levels (p<0.01). In the personality test, self-consciousness, misdeeds and family relationships showed significant differences between the upper and lower urine mercury groups (p<0.01), and specific reactions, ego resilience and hyperactivity also showed some differences (p<0.1). Conclusion: Some items in the neurobehavioral test, posturography test and personality test showed significant relations with biological mercury levels. Therefore, monitoring and appropriate management of students showing high mercury levels are recommended in order to reduce their mercury exposure.

• 사상체질의학회지
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• 제30권3호
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• pp.24-39
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• 2018

Introduction The purpose of this study was to systematically review previous studies on Sasang type-specific pathophysiological symptoms in urination and defecation. Methods Peer-reviewed articles on type-specific pathophysiological symptoms of urination and defecation published until September 2016 were extracted from domestic and international six databases. Clinical characteristics from thirteen extracted articles were categorized into three urination domains of appearance of urine, capacity of bladder and urinary discomfort, and three defecation domains of irritability of bowel movement, functional constipation and discomfort from irregularity. Results As for the urination, Tae-Eum type showed dark color with foam, however So-Eum type had frequent urination and sensitivity to dysuria but no nocturia and residual urine sense. As for the defecation, So-Yang type showed frequent urgency and constipation, however So-Eum type reported loose stool. So-Yang type showed varied level of health status depending on defecation irregularity. There were disparities with rectal tenesmus among Sasang types. Discussion Six domains of urination and defecation related type-specific pathophysiological clinical symptoms were provided in this study. This study would contribute to the standardized clinical measures of Sasang typology in the near future.

• 한국통신학회논문지
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• 제31권10C호
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• pp.964-972
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• 2006

신장은 간장과 가장 유기적인 관계가 깊은 장기로 혈액 중에서 체내 신진대사 결과 생긴 노폐물을 걸러내 오줌을 만들어 체외로 배출하는 기능을 한다. 그러나 신장은 문제가 발생할 경우 인체가 느끼는 자각증상이 크지 않기 때문에 장기 파손이 상당 부분 진행되어야 그 증상을 알게 된다. 따라서 사회적으로 신장 질환 진단에 대한 중요성이 증대되고 있다. 이를 위해 본 논문에서는 한방의 4대 진단법 중에서 망진과 청진 분야를 이용하여 신장질환에 대한 진단 방법을 제안하고자 한다. 본 논문에서 개발할 시스템은 크게 두 가지로 나누어진다. 하나는 입력 영상에 대한 보정을 통해 정확한 색상 값을 추출하고 최적화된 결과 영상을 통해 신장과 관련된 얼굴에서의 지각 부분의 색을 분석하고 그 값을 이용하여 신장 질환 진단을 하고자 한다. 또 하나는 신장과 음성 신호와의 관계론 비교, 분석하여 이를 입증하는 시스템을 설계하고자 한다. 끝으로 실험을 통해 제안한 방법의 유용성을 입증하고자 한다.

• 사상체질의학회지
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• 제29권3호
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• pp.248-261
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• 2017

Objectives The purpose of this study is to analyze the decision making process of prescribing Yeoldahanso-tang and Taeeumjowi-tang Choweseuncheng-tang using decision tree. Methods We used collected the prospective clinical data of TE type from September 2012 to July 2015. In this study, we used gender, BMI, blood pressure, pulse and clinical symptoms (digestion, sweat, defecation, urination, sleep, physical status, emotion, heat-coldness, water consumption, facial color) as variables. Decision trees were analyzed using open source R version 3.3.2. Results & Conclusions We found that the decision trees differed among institutions. However, in all institutions, it was found that stool type (ordinary symptom), urine frequency (ordinary and present symptom) and anxiety (ordinary symptom) were important in the decision of prescription. Besides, clinical informations such as sex, Body Mass Index and blood pressure affected the prescription decision.

• 동의생리병리학회지
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• 제19권3호
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• pp.580-585
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• 2005

Treatment chart(醫案) is a document that doctors have described about their own practice. Western doctor's chart has a prescribed form, but otherwise chart of oriental medicine is a free form. As It has no prescribed form, doctors of oriental medicine have recorded important facts that they think especially. For example, details are patient's name, age, sex and address, the name of disease, state of pulse and tongue, state of secretions(stools, urine, perspiration, etc.), color of face, state of sleep and thirst, diagnosis, prescription, improvement of herb, teaching, and so forth. If we study on chart of oriental medicine, we draw a lesson about practices of a famous doctors. Through that we can increase ability of diagnosis and adaptation to circumstance, make ourselves familiar with use of past prescriptions and way of changing prescription, and learn narrative story of past doctors' personal experience, their though and teaching. As chart of oriental medicine had many methods to take a measure to meet the false situation, we can learn that. Through chart of oriental medicine, we can improve our practice of oriental medicine.

• Bulletin of the Korean Chemical Society
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• 제35권4호
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• pp.1159-1164
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• 2014

A simple, highly sensitive and selective method based on the rhodamine B-covered gold nanoparticle with dual-readout (colorimetric and fluorometric) detection for $\small{L}$-cysteine is proposed. A mechanism is that citrate-stabilized AuNPs were modified with RB by electrostatic interaction, which enables the nanometal surface energy transfer (NSET) from the RB to the AuNPs, quenching the fluorescence. In the presence of $\small{L}$-cysteine, it was used as a competitor in the NSET by the strongly Au-S bonding to release RB from the Au surface and recover the fluorescence, and the red-to-purple color change quickly, which was monitored simply by the naked eye. Under the optimum conditions, the detection limit is as low as 10 nM. The method possessed the advantages of simplicity, rapidity and sensitivity at the same time. The method was also successfully applied to the determination of $\small{L}$-cysteine in human urine samples, and the results were satisfying.