• 제목/요약/키워드: Up-scaling

검색결과 346건 처리시간 0.025초

Minocycline 국소 약물 방출 제제의 치주질환 치료 효과 (Effects of locally-delivered minocycline hcl on controlled periodontal disease)

  • 정미현;권영혁;허익;이만섭;박준봉
    • Journal of Periodontal and Implant Science
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    • 제28권1호
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    • pp.37-56
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    • 1998
  • The purpose of this study was to evaluate the clinical and microbiological outcomes following the use of 30% minocycline-loaded polycaprolacton film and 2% minocycline-loaded gel that was applied locally into pockets combined with scaling and root planing. 25 human subjects who were non-pregnant, non-lactating, aged 20-50 and diagnosed as moderate to advanced adult periodontitis were enrolled. Subjects were excluded if they had a history of severe acute or chronic systemic disease, if they required antibiotic prophylaxis for dental treatment for any reason, or if they reported a history suggestive of hypersensitivity reactions to minocycline or tetracycline. 4quadrants that had several teeth with a 5-8mm probing pocket depth and radiographic evidence of alveolar bone loss for each patient were selected and divided into test sites and control sites according to the split-mouth design. Scaling and root planing was done for each site at baseline(0week). Test sites received the minocycline gel and strip and control sites had saline irrigation. The patients received both treatments simyltaneously. Subgingival irrigation of sterile saline was applied to the control sites for approximately 30 seconds. Minocycline strip and gel was applied into the periodontal pocket at 1, 2, 3, 4 weeks each after scaling and root planing in the test sites. The clinical and microbiological measurements were made at baseline and at the follow-up visits 6, 10, 14, 20 weeks. The results of this study were as follows; 1. The sulcular bleeding index, probing pocket depth and Periocheck test was significantly reduced and the relative proportions of spirochetes and motile rods were significantly reduced and the proportion of cocci was correspondingly increased, in locally delivered minocycline strip group compared to saline irrigation group. 2. In locally delivered minocycline gel group, The effect was the same with minocycline strip group as compared with saline irrigation therapy. 3. There was no significant differences between minocycline strip group and minocycline gelgroup. In conclusion, minocycline HCl local drug delivery combined with scaling and root planing may provide added improvement of clinical and microbiological responses by inhibiting bacterial recolonization of treated sites. It is suggested that the local administration of minocycline-HCl in the periodontal pocket is effective when combined with subgingival mechanical debridement.

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Principal Component Analysis와 Multi-Dimensional Scaling 분석을 이용한 시화공단 시흥천의 수질지표 및 미생물 군집 분포 연구 (Assessing Water Quality of Siheung Stream in Shihwa Industrial Complex Using Both Principal Component Analysis and Multi-Dimensional Scaling Analysis of Korean Water Quality Index and Microbial Community Data)

  • 서경진;김주미;김민정;김성근;이지은;김인영;조경덕;고광표
    • 한국환경보건학회지
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    • 제35권6호
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    • pp.517-525
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    • 2009
  • The water quality of Lake Shihwa had been rapidly deteriorating since 1994 due to wastewater input from the watersheds, limited water circulation and the lack of a wastewater treatment policy. In 2000, the government decided to open the tidal embankment and make a comprehensive management plan to improve the water quality, especially inflowing stream water around Shihwa and Banwol industrial complex. However, the water quality and microbial community have not as yet been fully evaluated. The purpose of this study is to investigate the influent water quality around the industrial area based on chemical and biological analysis, and collected surface water sample from the Siheung Stream, up-stream to down-stream through the industrial complex, Samples were collected in July 2009. The results show that the downstream site near the industrial complex had higher concentrations of heavy metals (Cu, Mn, Fe, Mg, and Zn) and organic matter than upstream sites. A combination of DGGE (Denaturing Gradient Gel Electrophoresis) gels, lists of K-WQI (Korean Water Quality Index), cluster analysis, MDS (Multi-Dimensional Scaling) and PCA (Principal Component Analysis) has demonstrated clear clustering between Siheung stream 3 and 4 and with a high similarity and detected metal reducing bacteria (Shewanella spp.) and biodegrading bacteria (Acinetobacter spp.). These results suggest that use of both chemical and microbiological marker would be useful to fully evaluate the water quality.

H.264/AVC 복호화기에서 복호된 인트라 모드 정보를 이용한 화면 해상도 변환 방법 (Image scaling scheme using the intra mode information in H.264/AVC decoder)

  • 채진기;한종기
    • 한국방송∙미디어공학회:학술대회논문집
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    • 한국방송공학회 2013년도 하계학술대회
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    • pp.296-299
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    • 2013
  • 디스플레이 기술이 발전함에 따라 다양한 크기의 디스플레이를 탑재한 장치들이 등장하게 되었고, 다양한 디스플레이 크기만큼 다양한 해상도를 사용하고 있다. 때문에 비디오 코덱과 scaler는 보편적으로 함께 사용된다. 그러나 기존의 scaler는 비디오 코덱의 복호화기와 화면 해상도 변환 모듈이 독립적으로 구성되고, 서로 간에 정보를 이용하지 않으므로 시스템의 성능 개선에 한계가 존재하였다. 즉, 비디오 코덱의 복호화기는 비트스트림으로부터 복호한 정보를 바탕으로 영상을 복원하고, 복원영상은 up/down scaler에서 확대/축소를 수행한다. 하지만 비디오 코덱의 비트스트림에 존재하는 정보는 영상의 특성을 반영하기 때문에 up/down scaler에서 비디오 코덱의 복호화기에서 복호된 정보를 이용하면 복잡도의 증가 없이 효율적인 확대/축소를 수행할 수 있다. 이에 본 논문에서는 비디오 코덱 중 차세대 비디오 코덱인 H.264/AVC 복호화기에서 생성된 복원 영상에 대해서 별도로 영상의 특성을 계산하는 모듈 없이 H.264/AVC 복호화기에서 복원된 정보 중 인트라 모드 정보를 바탕으로 영상의 특성에 맞는 up/down scaler를 구현하는 방법을 제안한다. 이 방법은 기존의 scaler들보다 물체의 경계영역을 더 선명하게 확대하는 효과를 보인다.

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Group Delay를 이용한 모바일 기기용 고성능 해상도 확대기의 하드웨어 구현 (Hardware Implementation of an Advanced Image Scaler for Mobile Device Using the Group Delay)

  • 김주현;박정환;최원태;강봉순
    • 융합신호처리학회논문지
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    • 제8권3호
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    • pp.163-170
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    • 2007
  • 본 논문에서는 bicubic 방법보다 하드웨어 구조는 간단하면서 확대 이미지는 더욱 선명한 polyphase scaler를 제안하였다. 제안된 시스템은 새로운 픽셀을 얻기 위해서 디지털 필터의 group delay를 이용하여 해상도를 확대하는 방식을 사용하였으며 bicubic 방법과 비교하여 더 좋은 성능을 가지면서 하드웨어 구조를 간단히 하여 모바일 기기 등에 쉽게 적용이 가능하도록 설계하였다. 기존 polyhpase 필터는 해상도 확대시 영상을 흐릿하게 하는 blurring 노이즈가 발생하는 문제점을 가지고 있었다. 그래서 입력 신호의 고주파 성분을 증폭시키도록 Polyphase 필터를 boost-up 필터로 수정하여 보다 선명한 결과를 얻을 수 있었다. 본 논문에서 제안하는 polyphase scaler는 Xilinx Virtex2 FPGA를 이용하여 하드웨어 검증을 수행하였다. 제안된 polyphase scaler는 핸드폰 카메라의 디지털 줌으로 사용되어 질 수 있다.

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임플란트 환자의 잇솔질 교육경험에 따른 유지관리행태 연구 (Study of maintenance behavior based on the experience of the tooth brushing instruction for implant patient)

  • 전지현;민희홍
    • 한국치위생학회지
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    • 제13권3호
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    • pp.403-410
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    • 2013
  • Objectives : This study aims to provide the basic data for the maintenance and management of healthy implants through finding out the educational experience of toothbrushing and the oral hygiene management for the implant patients and to determine the maintenance measure. Methods : From April 1 to october 1, 2012, 250 patients in the dental clinic in Daejeon completed the self-reported questionnaire. Results : As for the educational experience of toothbrushing, 66.4 percent received the training for toothbrushing and 33.6 percent had not received the training for toothbrushing. Those who brushed three times a day accounted for 74.1 percent. Those who received the training for toothbrushing comprised 56.0 percent and took regular check up of every 6 months. Approximately 50.0% received regular scaling service every 6 months. Periodical medical check up comprised 55.6% among those who received toothbrushing education. Approximately 63.9% thought that periodical medical check up is the most important to maintain oral health. Conclusions : There were important factors for oral health. They were tooth-brushing, the utilization of various oral hygienic products, and the awareness of importance of oral hygiene management. The customized education program for the general public should be implemented as regular as possible.

지명을 통한 장소정체성 재현과 지명영역의 변화 : 충주지역 지명을 사례로 (The Change of Geographical Names' Territory and Representation of Place Identity with Place Names : A Case Study of Chungju Geographical Names)

  • 이영희
    • 한국지역지리학회지
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    • 제16권2호
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    • pp.110-122
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    • 2010
  • 본 연구에서는 지명연구 방법의 다양화를 위해 장소정체성과 스케일 정치 그리고 영역경합의 세 가지 개념을 사용하여 충주지역 지명의 특성을 밝혀보고자 하였다. 먼저 장소정체성과 관련하여 새로 바뀐 충주시 '수안보면'은 이전의 지명인 상모면보다 지역이 가지고 있는 천연자원인 온천의 속성을 크게 부각시킬 뿐만 아니라 정체성의 구성 조건인 '수적 유일성'과 '질적 동일성', 그리고 '자아 동일성'을 가지고 있어 이 지역의 장소정체성을 잘 드러내고 있다. 둘째, 지명을 통한 스케일 정치는 스케일의 상승과 하강으로 구분하여 살펴볼 수 있는데 지명 스케일 상승의 사례로는 충주시 이류면의 옛 지명인 이안면을 들 수 있고, 하강의 사례로는 조선시대 읍호승강제에 따른 충주의 읍호승강과 1917년 행정구역개편 때 충주군현 지명이 충주면으로 축소된 경우와 일본에 의한 월악산의 한자지명의 변경을 들 수 있다. 셋째, 지명 영역변화의 사례로는 지명 표기자가 지명 영역과 더불어 변화한 경우와 그렇지 않은 경우가 있는데, 먼저 지명 표기자가 지명 영역과 함께 변화한 사례로는 충주시 용두동과 이류면 금곡리가 있다. 지명 표기자가 변하지 않으면서 지명 영역이 변화한 경우는 현재 충주시를 동서로 흐르는 달천을 들 수 있다. 결론적으로 본 연구결과는 지명이 장소정체성을 재현하고 구축하는데 활용될 수 있다는 점을 시사한다.

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Effect of scaling and root planing on the expression of anti-inflammatory cytokines (IL-4, IL-9, IL-10, and IL-13) in the gingival crevicular fluid of electronic cigarette users and non-smokers with moderate chronic periodontitis

  • Al-Hamoudi, Nawwaf;Alsahhaf, Abdulaziz;Deeb, Modhi Al;Alrabiah, Mohammed;Vohra, Fahim;Abduljabbar, Tariq
    • Journal of Periodontal and Implant Science
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    • 제50권2호
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    • pp.74-82
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    • 2020
  • Purpose: The aim of this cross-sectional study was to investigate the effect of scaling and root planing (SRP) on the expression of anti-inflammatory cytokines (interleukin [IL]-4, IL-9, IL-10, and IL-13) in the gingival crevicular fluid (GCF) of electronic cigarette users and non-smokers with moderate chronic periodontitis (CP). Methods: Electronic cigarette users and non-smokers with CP were included in the study. Full-mouth plaque and gingival indices, probing depth (PD), clinical attachment loss (CAL), and marginal bone loss (MBL) were assessed. The GCF was collected, and its volume and levels of IL-4, IL-9, IL-10, and IL-13 were assessed. These parameters were evaluated at baseline and 3 months after SRP. The sample size was estimated, and comparisons between groups were performed. P<0.05 was considered to indicate statistical significance. Results: Thirty-six electronic cigarette users (47.7±5.8 years old) and 35 non-smokers (46.5±3.4 years old) with CP were included. At baseline, there were no differences in plaque index (PI), PD, CAL, MBL, and GCF IL-4, IL-9, IL-10, and IL-13 between electronic cigarette users and nonsmokers. At the 3-month follow-up, there were no significant differences in PI, gingival index (GI), PD, CAL, and MBL in electronic cigarette users compared to baseline, while there were significant reductions in PI, GI, and PD among non-smokers. At the 3-month follow-up, GCF IL-4, IL-9, IL-10, and IL-13 levels were significantly elevated in both groups (P<0.05) compared to baseline. The increases in GCF IL-4, IL-9, IL-10, and IL-13 levels were significantly higher in non-smokers (P<0.05) than in electronic cigarette users at the 3-month follow-up. Conclusions: Levels of GCF IL-4, IL-9, IL-10, and IL-13 increased after SRP in electronic cigarette users and non-smokers with CP; however, the anti-inflammatory effect of SRP was more profound in non-smokers than in electronic cigarette users.

롤투롤 공정을 활용한 평판형 분리막의 대면적 제조 연구 (Scale-up Fabrication of Flat Sheet Membrane by Using a Roll-to-Roll Process)

  • 백동혁;유영민;김인철;박유인;남승은;조영훈
    • 멤브레인
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    • 제34권1호
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    • pp.79-86
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    • 2024
  • 고분자 분리막의 대표적인 형태 중 하나인 평판형 분리막은 제조가 용이하여 실험실에서 분리막 소재 연구에서부터 실제 상용 분리막 생산에 이르기까지 널리 활용되는 분리막의 형태이다. 정밀여과 및 한외여과 등에 사용되는 평판형의 다공성 고분자 분리막은 주로 상분리 공정을 통해 제조할 수 있으며, 여기에는 비용매 유도 및 증기 유도 상분리 공정이 활용된다. 그러나 상분리 공정 특성상 주변 환경과 실험자에 따라 샘플 간 편차가 쉽게 발생하여 재현성의 확보가 어려운 점이 있다. 따라서 개발된 제조기술을 스케일업 및 재현성 확보를 위해 제어된 환경에서 연속식 대면적 제조가 가능한 롤투롤 제조장치가 필요하며, 본 연구에서는 실험실 스케일의 제조기술을 나이프 및 슬롯다이 롤투롤 공정으로 스케일 업 했을 때 나타나는 제조 환경 차이에 따른 분리막의 특성 변화를 비교하였다. 최종적으로 연속식 제조공정 인자에 대한 최적화를 통해 대면적 제조 시 분리막의 균일성을 확보하였다.

Clinical factors affecting the longevity of fixed retainers and the influence of fixed retainers on periodontal health in periodontitis patients: a retrospective study

  • Han, Ji-Young;Park, Seo Hee;Kim, Joohyung;Hwang, Kyung-Gyun;Park, Chang-Joo
    • Journal of Periodontal and Implant Science
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    • 제51권3호
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    • pp.163-178
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    • 2021
  • Purpose: The aim of this study was to evaluate clinical factors affecting the longevity of fixed retainers and the influence of fixed retainers on periodontal health in periodontitis patients. Methods: In total, 52 patients with at least 2 years of follow-up after periodontal and orthodontic treatment were included in this study. After scaling and root planing, orthodontic treatment with fixed appliances or clear aligners was performed. Fixed retainers with twist-flex stainless steel wires were bonded to the palatal or lingual sides of anterior teeth. Changes in clinical parameters, including the plaque index, gingival index, calculus index (CI), probing pocket depth, and radiographic bone levels, were evaluated before bonding of fixed retainers and at a 12-month follow-up. Cumulative survival rates (CSRs) for retainer failure were evaluated according to sex, site, CI, stage of periodontitis, and the severity of the irregularity with the log-rank test and hazard ratios (HRs). Results: Twelve months after bonding of fixed retainers, improvements were observed in all clinical parameters except CI and radiographic bone gain. The overall CSR of the retainers with a CI <1 at the 12-month follow-up after bonding of fixed retainers was significantly higher than that of the retainers with a CI ≥1 at the 12-month follow-up (log-rank test; P<0.001). Patients with stage III (grade B or C) periodontitis had a higher multivariate HR for retainer failure (5.4; 95% confidence interval, 1.22-23.91; P=0.026) than patients with stage I (grade A or B) periodontitis. Conclusions: Although fixed retainers were bonded in periodontitis patients, periodontal health was well maintained if supportive periodontal treatment with repeated oral hygiene education was provided. Nonetheless, fixed retainer failure occurred more frequently in patients who had stage III (grade B or C) periodontitis or a CI ≥1 at 12-month follow-up after bonding of fixed retainers.

컨택트 작업 시 햅틱 인터렉션의 투명성 향상을 위한 Virtual Coupling 기법의 설계 (Toward Transparent Virtual Coupling for Haptic Interaction during Contact Tasks)

  • 김명신;이동준
    • 로봇학회논문지
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    • 제8권3호
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    • pp.186-196
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    • 2013
  • Since its introduction (e.g., [4, 6]), virtual coupling technique has been de facto way to connect a haptic device with a virtual proxy for haptic rendering and control. However, because of the single dependence on spring-damper feedback action, this virtual coupling suffers from the degraded transparency particularly during contact tasks when large device/proxy-forces are involved. In this paper, we propose a novel virtual coupling technique, which, by utilizing passive decomposition, reduces device-proxy position deviation even during the contact tasks while also scaling down (or up) the apparent inertia of the coordinated device-proxy. By doing so, we can significantly improve transparency between multiple degree of freedom (possibly nonlinear) haptic device and virtual proxy. In other to use passive decomposition, disturbance observer of [3] is adopted to estimate human force with some dead-zone modification to avoid "winding-up" force estimation in the presence of device torque saturation. Some preliminary experimental results are also given to illustrate efficacy of the proposed technique.