• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.10 no.4
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• pp.116-124
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• 2011

For Binary CDMA network, communication can be accomplished only within a Pico-net on the boundary of management by the master station because it manages network resources of each entity. In this research, we try to overcome these limits and extend the application for Binary CDMA system to broad-band network. We suggest a new Binary CDMA router such that network is devised by cell unit and multiple Pico-net and a unique address is assigned to each Pico-cell to relaying data between Pico-cells.

• Clinical and Experimental Reproductive Medicine
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• v.45 no.4
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• pp.154-162
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• 2018

Objective: The fallopian tubes play a critical role in the early events of fertilization. The rapid innate immune defense is an important part of the fallopian tubes. Toll-like receptor 3 (TLR3), as a part of the innate immune system, plays an important role in detecting viral infections. In this basic and experimental study, the effect of sex hormones on the function of TLR3 in the OE-E6/E7 cell line was investigated. Methods: The functionality of TLR3 in this cell line was evaluated by cytokine measurements (interleukin [IL]-6 and IL-1b) and the effects of sex hormones on TLR3 were tested by an enzyme-linked immunosorbent assay kit. Additionally, TLR3 small interfering RNA (siRNA) and a TLR3 function-blocking antibody were used to confirm our findings. Results: The production of IL-6 significantly increased in the presence of polyinosinic-polycytidylic acid (poly(I:C)) as the TLR3 ligand. Using a TLR3-siRNA-ransfected OE-E6/E7 cell line and function-blocking antibody confirmed that cytokine production was due to TLR3. In addition, 17-${\beta}$ estradiol and progesterone suppressed the production of IL-6 in the presence and absence of poly(I:C). Conclusion: These results imply that sex hormones exerted a suppressive effect on the function of TLR3 in the fallopian tube cell line when different concentrations of sex hormones were present. The current results also suggest that estrogen receptor beta and nuclear progesterone receptor B are likely to mediate the hormonal regulation of TLR3, as these two receptors are the main estrogen and progesterone receptors in OEE6/E7 cell line.

• Korean Journal of Plant Tissue Culture
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• v.24 no.1
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• pp.57-61
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• 1997

We investigated changes in the superoxide dismutase (SOD) activity and SOD isoenzyme pattern in suspension cultures of tomato (Lycopersicon esculentum), which were compared with those of intact tomato plants. two grams (fr wt) of cells subcultured at 15-day intervals were inoculated into 50 mL MS medium containing l mg/L 2,4-D and 30 g/L sucrose in a 300 mL flask and maintained at $25^{\circ}C$ in the dark (100 rpm). The cell growth reached a maximum at 20 days after subculture (DAS), followed by a rapid decrease with further cultures. The cell colour changed from white to black from 23 DAS. The intracellular SOD activity (units/g cell dry wt) was significantly increased from 23 DAS and reached a maximum at 28 DAS (52,400 units), followed by a decrease with further cultures, whereas the extracellular SOD activity showed a maximum at 25 DAS (27,800 units/50 mL medium). The total SOD activity per flask showed a maximum at 25 DAS (35,700 units), in which the extracellular SOD activity occupied about 75%. The tomato cultured cells had four SOD isoenzymes and their patterns were well correlated with SOD activity without a qualitative change during the cell cultures. The intact tomato plants had an additional CuZnSOD isoenzyme, showing the different isoenzyme patterns from cultured cells.

• The Journal of Engineering Geology
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• v.18 no.4
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• pp.405-414
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• 2008

When we evaluate slope stability, we regard the slope homogeneous and evaluate slope stability at the most dangerous portion of slope. However, since conditions and properties of rock mass/soil are different from one location to another within a single slope, slope stability evaluated by current concept can not represent slope correctly. This also result in over-reinforcement at the portion where reinforcement is not necessary. In order to solve these problems, we suggest a cell unit evaluation method in which we apply small rectangular cells in a slope and regard each cell as a single slope. In this method, slopes are classified into soil slope and rock slope depending on materials. Strength of rock, volumetric joint count, spacing of joints, condition of joints, ground water condition and so on are examined and SMR and condition index values are calculated. Finally, all data and results are presented as contour maps. We apply the cell unit evaluation method into 3 cut slopes. SMR values estimated by the new method are larger than those by current concept at most portions of slope, indicating that the new method suggested by this research represent slope stability more correctly than methods which were used. This method will prevent over-reinforcement at the portion of slope where reinforcement is not necessary.

• The Korean Journal of Physiology and Pharmacology
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• v.20 no.4
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• pp.333-340
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• 2016

Edaravone, a synthetic-free radical scavenger, has been reported to reduce ischemia-reperfusion-induced renal injury by improving tubular cell function, and lowering serum creatinine and renal vascular resistance. The present study investigated the effect of edaravone in diabetes mellitus-induced nephropathy in rats. A single administration of streptozotocin (STZ, 55 mg/kg, i .p.) was employed to induce diabetes mellitus in rats. The STZ-administered diabetic rats were allowed for 10 weeks to develop nephropathy. Mean body weight, lipid alteration, renal functional and histopathology were analysed. Diabetic rats developed nephropathy as evidenced by a significant increase in serum creatinine and urea, and marked renal histopathological abnormalities like glomerulosclerosis and tubular cell degeneration. The kidney weight to body weight ratio was increased. Moreover, diabetic rats showed lipid alteration as evidenced by a significant increase in serum triglycerides and decrease in serum high-density lipoproteins. Edaravone (10 mg/kg, i .p., last 4-weeks) treatment markedly prevented the development of nephropathy in diabetic rats by reducing serum creatinine and urea and preventing renal structural abnormalities. In addition, its treatment, without significantly altering the elevated glucose level in diabetic rats, prevented diabetes mellitus-induced lipid alteration by reducing serum triglycerides and increasing serum high-density lipoproteins. Interestingly, the renoprotective effect of edaravone was comparable to that of lisinopril (5 mg/kg, p.o, 4 weeks, standard drug). Edaravone prevented renal structural and functional abnormalities and lipid alteration associated with experimental diabetes mellitus. Edaravone has a potential to prevent nephropathy without showing an anti-diabetic action, implicating its direct renoprotection in diabetic rats.

• BMB Reports
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• v.32 no.6
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• pp.561-566
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• 1999

CA(1-8)-ME(1-12) [CA-ME], composed of cecropin A(1-8) and melittin(1-12), is a synthetic antimicrobial peptide having potent antibacterial and antitumor activities with minimal hemolytic activity. In order to investigate the effects of the flexible hinge sequence, Gly-Ile-Gly, of CA-ME on antibiotic activity, CA-ME and three analogues, CA-ME1, CA-ME2, and CA-ME3, were synthesized. The Gly-Ile-Gly sequence of Ca-ME was deleted in CA-ME1 and replaced with Pro and Gly-Pro-Gly in CA-ME2 and CA-ME3, respectively. CA-ME1 and CA-ME3 showed a significant decrease in antitumor activity and phospholipid vesicle-disrupting ability. However, CA-ME2 showed similar antitumor and vesicle-disrupting activities, as compared with CA-ME. These results suggest that the flexibility or ${\beta}$-turn induced by Gly-Ile-Gly or Pro in the central part of CA-ME may be important in the electrostatic interaction of the N-terminus cationic ${\alpha}$-helical region with the cell membrane surface and the hydrophobic interaction of the C-terminus amphipathic ${\alpha}$-helical region with the hydrophobic acyl chains in the cell membrane. CA-ME3 exhibited lower antitumor and vesicle-disrupting activities than CA-ME and CA-ME2. This result suggests that the excessive ${\beta}$-turn structure caused by the Gly-Pro-Gly sequence in CA-ME3 seems to interrupt ion channel/pore formation in the lipid bilayer. We concluded that the appropriate flexibility or bilayer. We concluded that the appropriate flexibility or ${\beta}$-turn structure provided by the central hinge is responsible for the effective antibiotic activity of the antimicrobial peptides with the helix-hinge-helix structure.

• Journal of Satellite, Information and Communications
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• v.12 no.4
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• pp.95-99
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• 2017

The lifetime of a battery that supplies all the power required by a satellite in the eclipse is directly related to the lifetime of the satellite. Because the lifetime of the battery is influenced by the charging method of the battery, the power control unit that controls the charging of the battery should be designed in consideration of battery life. The battery charging is performed by controlling the charge current in the power control unit generated from the solar cell in the daytime. In order to prevent overcharge of the battery and for considering frequency of eclipse in each season, parameters related battery charging should be designed differently according to the season and to prevent over-current charging and over-voltage charging during charging, charge current is controlled by monitoring battery charge / discharge status, charge current amount, battery voltage, battery capacity, battery temperature and battery cell voltage. In satellite, tapering method is used to control charge current by reflecting each condition. In this paper, design battery charging algorithm of satellite power control unit using tapering charging method. convert the designed algorithm into a code that can be uploaded to satellites and verify the operation through testing in the established satellite environment.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2012.10a
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• pp.267-271
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• 2012

In this paper a power management unit for solar energy harvesting is proposed. If solar energy is sufficient, Power Management Unit(PMU) directly supplies load with solar energy. By contrast, if solar energy is insufficient to operate sensor nodes, voltage booster(VB) boosts the solar cell's output voltage, and then PMU supplies load with the harvested energy. The designed circuit had been fabricated using a 018um CMOS process. In the first case, the PMU supplies load with more energy than in the second case. In the second case where a VB is used, the PMU operates to supply load with solar energy even when illumination is low and minimum solar cells with very low output voltage are used.

• Bulletin of the Korean Chemical Society
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• v.10 no.3
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• pp.234-238
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• 1989

The crystal structure of partially $Ag^+$-exchanged zeolite A, $Ag_{3.2}Na_{8.8}$-A, vacuum dehydrated at $360^{\circ}C$ and then exposed to 0.1 torr of cesium vapor for 12 hours at $250^{\circ}C$ has been determined by single-crystal X-ray diffraction techniques in the cubic space group Pm3m (a = 12.262(2)${\AA})\;at\;21(1)^{\circ}C$. The structure was refined to the final error indexes $R_1=0.068\;and\;R_2=0.072$ by using 338 reflections for which $I_o\;>\;3{\sigma}(I_o)$ and the composition of unit cell is $Ag_{3.2}Cs_{8.8}-A.\;3\;Cs^+$ ions lie on the centers of the 8-rings at sites of D4h symmetry. Two crystallographycally different 6-ring $Cs^+$ ions were found: 1.5 $Cs^+$ ions at Cs(2) are located inside of sodalite cavity and 4.3 $Cs^+$ ions at Cs(3) are located in the large cavity. The fractional occupancies observed at Cs(2) and Cs(3) indicate that the existence of at least three types of unit cells with regard to the 6-ring $Cs^+$ ions. For example, 50% of unit cells may have two $Cs^+$ ions at Cs(2) and 4 $Cs^+$ ions at Cs(3). 30% of unit cells may have one Cs+ ion at Cs(2) and 5 $Cs^+$ ions at Cs(3). The remaining 20% would have one $Cs^+$ ion at Cs(2) and 4 $Cs^+$ ions at Cs(3). On threefold axes of the unit cell two non-equivalent Ag atom positions are found in the large cavity, each containing 0.64 and 1.92 Ag atoms, respectively. A crystallographic analysis may be interpreted to indicate that 0.64 $(Ag_5)^+$ clusters are present in each large cavity. This cluster may be viewed as a tetrasilver molecule $(Ag_4)^0$(bond length, 2.84${\AA}$) stabilized by the coordination of one $Ag^+$ ion.

• Journal of the Korean Solar Energy Society
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• v.25 no.3
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• pp.47-52
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• 2005

Normally if sunlight is directed on a solar cell without any increasing in temperature, the amount of absorption energy per unit area of each cell is increasing. In a silicon solar cell. however, cell conversion efficiency decreases with the increase of temperature. Therefore, to maintain cell conversion efficiency under normal condition, it is necessary to keep the cell at operating temperature. We tried to design and make new hybrid panel with cooling system to prevent increasing of temperature on cell, collect and use thermal energy more effectively. We compared performance of this new hybrid panel with current thermal panel. We also evaluated conversion efficiency, thermal capacity and confirmed cooling effects from thermal absorption efficiency.