• Asian Pacific Journal of Cancer Prevention
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• 제15권1호
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• pp.221-227
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• 2014

Background: Aberrant phenotypes in acute leukemia have variable frequency and their prognostic and predictive relevance is controversial, despite several reports of clinical significance. Aims: To determine the prevalence of aberrant antigen expression in acute leukemia, assess clinical relevance and demonstrate immunophenotype-karyotype correlations. Materials and Methods: A total of 73 (40 AML and 33 ALL) newly diagnosed acute leukemia cases presenting to KAMC, Kingdom of Saudi Arabia, were included. Diagnosis was based on WHO criteria and FAB classification. Immunophenotyping by flow cytometry, conventional karyotyping and fluorescence in situ hybridization for gene rearrangements were performed. Results: Aberrant antigens were detected in 27/40 (67.5%) of AML and in 14/33 (42.4%) in ALL cases. There were statistically significant higher TLC in Ly+ AML than in Ly-AML (p=0.05) and significant higher blast count in ALL with aberrant antigens at presentation and day 14 (p=0.005, 0.046). There was no significant relation to clinical response, relapse free survival (RFS) or overall survival (p>0.05), but AML cases expressing ${\geq}2$ Ly antigens showed a lower median RFS than those expressing a single Ly antigen. In AML, CD 56 was expressed in 11/40. CD7 was expressed in 7/40, having a significant relation with an unfavorable cytogenetic pattern (p=0.046). CD4 was expressed in 5/40. CD19 was detected in 4/40 AML associated with M2 and t (8; 21). In ALL cases, CD33 was expressed in 7/33 and CD13 in 5/33. Regarding T Ag in B-ALL CD2 was expressed in 2 cases and CD56 in 3 cases. Conclusions: Aberrant antigen expression may be associated with adverse clinical data at presentation. AML cases expressing ${\geq}2$ Ly antigens may have shorter median RFS. No specific cytogenetic pattern is associated with aberrant antigen expression but individual antigens may be related to particular cytogenetic patterns. Immunophenotype-karyotype correlations need larger studies for confirmation.

• 지역연구
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• 제10권2호
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• pp.17-29
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• 1994

This study attempts to examine the regional distribution and the locational pattern of leisure facilities at Kangnam-gu in Seoul. For the convenience of the analysis the facilities are classified into public and private sector and then the facilities are classified into 11 types: mineral spring resort, play ground, neighborhood park, swimming pool, gymnasium, bowling, pingpong, aerobic, golf practice, health, and billiard facilities. For the purpose data was collected from statistical yearbook in 1993 and lists of registered facility at department of living physics of Kangnam-gu office. The data of the density of facilities and the opportunity of facilities per facilities type and per region are analysed with the technology of GIS. Results may be summarized as follows. First of all, correlation between the results of Location-Allocation model and the results of Interaction model is very high. Secondly, on comparing the density of facilities with the opportunity of the facility use per eleven facility types, three discrete spatial pattems are found. The mineral spring resort facility type with the highest unbalanced density and opportunity of facility use is to be found. Play ground, neighborhood park, swimming pool, gymnasium, bowling, pingpong, and aerobic facility types have the high unbalanced density and opportunity of facility use. The golf practice, health, and billiard facility types have spatially balanced density and opportunity of facility use. Thirdly, as comparing the density and the opportunity of the facility use per 'dong' administration unit, the spatial patterns of the public and the private facilities are different in density of the facility use and otherwise two are similar in the opportunity of the facility use. Fourthly, patterns of facilities users have different charateristics based on facility use time, expense, residence, and access time and four regional patterns are to be found ; user favorable, facility profitable, user balanced, and unfavorable.

• 혜화의학회지
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• 제20권1호
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• pp.1-10
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• 2011

By studying the portions and layers(分部), left and right, superior and inferior, location of yin and yang, and beginning and end of diseases of skin, which is the core point of the theory of cutaneous region(皮部論) in "Naejing(內經)", in the physiological and pathological perspective, based on opinion of historic memorial doctors, arrived to the conclusion as below. Cutaneous region means not only the distribution of three yin and three yang(三陰三陽) of the surface, but also inside and outside, shallowness and depth, and it is the system which unites meridians, networks, and vessels. It is divided into portions and layers. The origin and beginning of diseases and the rule of favorable pattern and unfavorable pattern can be known through it. The portion of skin is not only the area that meridian vessels belongs to skin, but also the area that activation of twelve meridian vessels are expressed in the surface. The layer of skin is consisted in order of skin-tertiary collateral vessel-collateral vessel-meridian vessel-bone. In "Naejing", there are two preconditions to divide three yin and three yang into yin and yang. The first is standing while looking the south, and second is the quotation "outside is side of yang(外者爲陽 內者爲陰)." According to this preconditions, yang of outside of yang brightness, lesser yang, and greater yang is the whole body, except inside of hand and foot which yin of lesser yin, pericardium, and greater yin. Superior and inferior of the portions and the layers is designated as hand and foot, theological basis of which superior and inferior work in same diagnostic method can be found in the root and the basis(標本) and the origin and the insertion(根結). In conclusion, cutaneous region not only manages layer of the skin, but also it is divided into layers and portions, so it has close relations between meridian vessels and collateral vessels. The in-depth study of cutaneous region and meridians should be progress, in order to practice of diagnosis and acupuncture and moxibustion more.

• The Journal of Advanced Prosthodontics
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• 제4권1호
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• pp.37-42
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• 2012

PURPOSE. The influence of the modified process in the fiber-reinforced post and resin core foundation treatment on the fracture resistance and failure pattern of premolar was tested in this study. MATERIALS AND METHODS. Thirty-six human mandibular premolars were divided into 4 groups (n = 9). In group DCT, the quartz fibre post (D.T. Light-post) was cemented with resin cement (DUO-LINK) and a core foundation was formed with composite resin (LIGHT-CORE). In group DMO and DMT, resin cement (DUO-LINK) was used for post (D.T. Lightpost) cementation and core foundation; in group DMO, these procedures were performed simultaneously in one step, while DMT group was accomplished in separated two steps. In group LCT, the glass fiber post (LuxaPost) cementation and core foundation was accomplished with composite resin (LuxaCore-Dual) in separated procedures. Tooth were prepared with 2 mm ferrule and restored with nickel-chromium crowns. A static loading test was carried out and loads were applied to the buccal surface of the buccal cusp at a 45 degree inclination to the long axis of the tooth until failure occurred. The data were analyzed with MANOVA (${\alpha}$= .05). The failure pattern was observed and classified as either favorable (allowing repair) or unfavorable (not allowing repair). RESULTS. The mean fracture strength was highest in group DCT followed in descending order by groups DMO, DMT, and LCT. However, there were no significant differences in fracture strength between the groups. A higher prevalence of favorable fractures was detected in group DMT but there were no significant differences between the groups. CONCLUSION. The change of post or core foundation method does not appear to influence the fracture strength and failure patterns.

• Restorative Dentistry and Endodontics
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• 제20권2호
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• pp.789-801
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• 1995

Canals with artificially made internal resorption were filled with 4 techniques(Lateral condensation, Ultrafil, Obtura II, Thermafil) to compare the efficacy of canal filling according to the filling techniques. After canal filling, radiographic examination, dye penetration through the apical portion and percentage of G-P filled area on the internal resorption area were evaluated. To examine the degree of crystal-like structure and the interface between filled G-P and canal wall, SM and SEM images were taken too. The results were as follows : 1. There was no statistically significant difference in apical microleakage among the 4 root canal filling techniques. 2. As a result of radiographic examination, Ultrafil was the best and Obtura II was acceptable but Lateral condensation and Thermafil showed unfavorable canal filling pattern similarly. 3. Ultrafil filled most of artificially made internal resorption area and Obtura II, Lateral condensation, Thermafil in that order filled unfavorably. 4. Degree of crystal like structure was the highest in the group filled with Ultrafil and those of Obtura II and Thermafil were similar and that of gutta percha used in Lateral condensation showed the lowest value. 5. Penetration of gutta percha into the dentinal tubules couldn't be seen in all groups. In the contact surface between the filled G-P and the canal wall, Lateral condensation showed relatively close sealing, Obtura II and Thermafil had irregular contact surface and Ultrafil showed regular filling pattern. 6. Contact surface between the core of Thermafil and the gutta percha showed close relationship without gap formation.

• 대한한의학원전학회지
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• 제21권3호
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• pp.177-258
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• 2008

An Epidemic disease is regarded as warm disease by Korean Medicine. Warm disease is highly contagious and shows an unfavorable condition, and that is characteristic of being widely prevalent. Warm disease study cope with this epidemic disease opportunely. In the Myeong[明] and Cheong[淸] Dynasty, warm disease study got into the region of Korean medicine of today and "The Sections of Warm Disease(溫病條辨)" contributed to the cause of the study was really great. "The Sections of Warm Disease" written by Ohguktong(吳鞠通) in the Cheong Dynasty are divided into the three sections of Upper burner[上焦], Middle burner[中焦] and Lower burner[下焦]. Ohguktong, dealing with the contents of Defense-aspect[衛分], Gi-aspect[氣分], Construction-aspect[營分], Blood-aspect[血分], and so forth in all "Sections of Warm Disease", made use of Seopcheonsa(葉天士)'s Defense Gi[衛氣], Construction, and Blood pattern identification with Triple burner[三焦] pattern identification and six channel pattern identification. And he, having a correct understanding of the nature of medicine, suggested in detail that the directions of medicine and described the processing according to method and the method to take medicine. To conclude, Ohguktong(吳鞠通) Tong in "The Sections of Warm Disease" not only formulated the system of the practical theory of warm disease but also solidified the foundation covering warm disease and its treatment as well, He established the new method of treatment and formula related to warm disease and made a definite distinction between cold damage[傷寒] and warm disease[溫病].

• Journal of Nutrition and Health
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• 제40권1호
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• pp.78-88
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• 2007

The purpose of this study was to investigate dietary fat and individual fatty acids intake pattern of 174 college women living in Seoul and Gyong-gi province through internet nutritional assessment system. Each of the subjects was required to input their own food intake for three days, which included two days during the week and one day of the weekend, on the web program directly and all of the data collected were used for statistical analysis. The mean daily caloric intake of the subjects was 1,500.9 kcal which was at 71.5% of Estimated Energy Requirement (EER). Dietary fat contributed 27.6% of the total caloric intake which was slightly higher than the recommended limit of 25%. Daily cholesterol intake was 310.0 mg, which was also high to some degree. Mean daily N6 and N3 fatty acid intake was 6.1 g and 0.9 g, respectively, and calory % calculated from each were 3.63% and 0.53%. This result showed the intake of N3 fatty acid fell in Acceptable Macronutrient Distribution Ranges (AMR) $0.5\sim1.0%$ but that of N6 fatty acid was somewhat lower than the AMDR $4\sim8%$. N6/N3 ratio 8.5/l, however, was within the desirable range $4\sim10/1$. Considering overall dietary fatty acids intake, oleic acid was the most abundant, followed by linoleic and palmitic acid. And among polyunsaturated fatty acids intake, linoleic acid was exclusively high, accounting for 97.4% of total N6 fatty acid intake. On the contrary, three fatty acids, linolenic (67.3%), DHA (21.1%) and EPA (10.0%), together supplied 98.4% of total N3 fatty acid intake. Mean P/M/S was 0.9/l.1/1.0. The subjects' intake of fat, many fatty acids and cholesterol came from diverse food groups including meats, fats and oils, milk and milk products, eggs, fish, and soybean products. Nevertheless, the subjects tended to show unfavorable fat and fatty acids intake pattern in terms of quantity and quality. Based on these results, it is important to monitor dietary fat intake pattern of the general population continuously and an internet program such as the one used for this study would be valuable, especially for assessing dietary patterns in the younger generation.

• 대한심미치과학회지
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• 제24권1호
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• pp.39-48
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• 2015

전치부 임플란트의 심미성에 영향을 미치는 중요한 요소는 다음과 같다. 1) 임플란트 식립체의 올바른 위치, 2) 치조골의 충분한 양, 3) 연조직의 최적의 양. 임플란트 위치는 심미적인 치료결과를 얻는 데에 가장 중요한 요소일 것이다. 임플란트의 3차원적 위치는 치조제의 위치와 방향에 의해 결정된다. 임상가들은 수복물을 제작할 때 흔히 자연치를 모방하려 한다. 그러나 심미적인 진단 및 치료를 하는 과정에서 잊지 말아야 할 것은 얼굴형태, 입술, 치은, 치조제, 그리고 잔존치아들과의 상관관계를 고려하는 것이다. 전치부는 구치부에 비해 생물학적으로 불리하며, 조금이라도 임플란트 위치가 틀어지면 심미적으로 좋지 않은 결과를 야기할 수 있다. 임플란트 3치원적 위치의 생물학적, 보철적 의미를 이해한다면, 전치부에 더욱 심미적인 결과를 얻을 수 있을 것이다.

• Wind and Structures
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• 제30권2호
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• pp.165-180
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• 2020

To determine tornadic wind loads, the wind pressure, forces and moments induced by tornadoes on civil structures have been studied. However, in most previous studies, only the individual building of interest was included in the wind field, which may be suitable to simulate the case where a tornado strikes rural areas. The statistical data has indicated that tornadoes induce more significant fatalities and property loss when they attack densely populated areas. To simulate this case, all buildings in the community of interest should be included in the wind field. However, this has been rarely studied. To bridge this research gap, this study will systematically investigate the influence of a community of buildings on tornadic wind fields by modeling all buildings in the community into the wind field (designated as "the Community case under tornadic winds"). For comparison, the case in which only a single building is included in the tornadic wind field (designated as "the Single-building case under tornadic winds") and the case where a community of buildings are included in the equivalent straight-line wind field (designated as "the Community case under straight-line winds") are also simulated. The results demonstrate that the presence of a number of buildings completely destroys the pattern of regular circular strips in the distribution of tangential velocity and pressure on horizontal planes. Above the roof height, the maximum tangential velocity is lower in the Community case under tornadic winds than that in the Single-building case under tornadic winds because of the higher surface friction in the Community case; below the roof height, greater tangential velocity and pressure are observed in the Community case under tornadic wind fields, and more unfavorable conditions are observed in the Community case under tornadic winds than under the equivalent straight-line winds.

• Applied Biological Chemistry
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• 제14권3호
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• pp.177-182
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• 1971

0.02M EDTA-2Na와 $Na_2S_2O_4$에 의한 벼잎의 철을 분별정량하는 새방법을 적고이병잎을 사용검정하였다. 1) 시도한 방법은 환원철($Fe^{++}$), 산화철($Fe^{+++}$), 침전철(PFe) 및 결합철(BFe)로 분별 정량할 수 있고 식물조직의 생리적상태를 잘 나타내었다. 2) 생리적으로 가장 알맞은 철풀의 패턴은 $Fe^{+++}>PFe>BFe>Fe^{++}$이고 보통인 때 $PFe>Fe^{+++}>BFe>Fe^{++}$이고 부적합한 때 $BFe>Fe^{+++}>PFe>Fe^{++}$이며 독작용이 있을 경우 $BPe>PFe>Fe^{+++}>Fe^{++}$임이 추정된다. 3) 전철에 대한 각철의 백분율은 환원철이 10이하 산화철과 침전철이 $20{\sim}40$이며 결합철은 $20{\sim}50$이었다. 4) 잎의 상부가 하반부에 비해 불건전한 증상임에도 언제나 환원철이 많은 것은 상반부에 환원철이 크게 관여하는 활동적 대사계가 있는 것을 의미한다.