• Geomechanics and Engineering
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• v.14 no.1
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• pp.19-27
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• 2018

It follows from the basic principles of mechanics of deformable solids relating to the strength, stability and propagation of elastic waves that the Earth's inner core cannot exist in the form of a spherical structure in the assumed thermobaric conditions and calculation values of physico-mechanical parameters. Pressure level reaches a value that is significantly greater than the theoretical limit of medium strength in the model approximations at the surface of the sphere of the inner core. On the other hand, equilibrium state of the sphere is unstable on the geometric forming at much lower loads under the influence of the "dead" surface loads. In case of the action of "follower" loads, the assumed pressure value on the surface of the sphere is comparable with the value of the critical load of "internal" instability. In these cases, due to the instability of the equilibrium state, propagation of homogeneous deformations becomes uneven in the sphere. Moreover, the elastic waves with actual velocity cannot propagate in such conditions in solid medium. Violation of these fundamental conditions of mechanics required in determining the physical and mechanical properties of the medium should be taken into account in the integrated interpretations of seismic and laboratory (experimental) data. In this case, application of the linear theory of elasticity and elastic waves does not ensure the reliability of results on the structure and composition of the Earth's core despite compliance with the required integral conditions on the mass, moment of inertia and natural oscillations of the Earth.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2345-2348
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• 2012

Epidemiological studies of cancer incidence in Kazakhstan have revealed an uneven distribution for cervical cancer. Incidence and mortality rates were calculated for different regions of the republic, including the two major cities of Almaty and Astana, in 1999-2008. Defined levels for cartograms for incidence were low (up to 12.8/100,000), medium (12.8 to 15.9) and high (above 15.9) and for mortality were up to 7.1, 7.1 to 10.8 and more than 10.8, respectively. Basically high incidence rates were identified in the eastern, central and northern parts of the country and in Almaty. Such differences in cervical cancer data, and also variation in mortality/ incidence ratios, from a low of 0.4 in Almaty to a high of 0.71 in Zhambyl, point to variation in demographic and medical features which impact on risk and prognistic factors for cervical cancer in the country. Further research is necessary to highlight areas for emphasis in cancer control programs for this important cancer.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.537-550
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• 2014

The actual burden of head and neck cancer in India is much greater than reflected through the existing literature and hence can be regarded as a 'tip of iceberg' situation. This has further been evident by the recent reports of 'Net-based Atlas of Cancer in India'. South-east Asia is likely to face sharp increases of over 75% in the number of cancer deaths in 2020 as compared to 2000. Since the percentage increase of Indian population has been nearly twice that of the world in last 15 years there is a likelihood of increase in cancer burden with the same proportion. The distribution of population based cancer registries is grossly uneven with certain important parts of the country being not represented at all and hence the current cancer burden is not reflected by registry data. However, the pathetic situation of health care system in major parts of the country as also emphasized by the World Bank, is not suitable to provide anywhere near accurate data on cancer burden. Head and neck cancer (including thyroid lesions) is third most common malignancy seen in both the sexes across the globe but is the commonest malignancy encountered in Indian males. Also oral cavity cancer is the most prevalent type amongst the males and one of the highest across the globe. This article reviews the latest global and national situation with an especial emphasis on head and neck cancer. Furthermore this review focuses on burden in different sub sites at national and global levels.

• Asian-Australasian Journal of Animal Sciences
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• v.10 no.5
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• pp.484-490
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• 1997

Spatial distribution of urination by Japanese Black heifers and steers was investigated, and compared with the distribution of defecation. The animals grazed a bahiagrass (Paspalum notatum $Fl\ddot{u}gge$) pasture in the daytime, and spent the rest of the day in a barn. The distribution of urination to the pasture was greater than that expected from the proportion of time that the animals spent in the pasture. Correspondingly, the distribution was smaller in the barn. Such a distribution pattern of urination to the pasture and barn was similar to that of defecation, and affected by the intake of supplement on the previous day. The distribution of urination within the pasture, i.e. the distribution to the paddock, alley and resting area, was often uneven on an area basis. The animals often urinated sparsely in the alley and resting area, while they urinated in the paddock almost proportionally to its area. This was a clear contrast to the distribution pattern of defecation, which was sparse in the paddock and dense in the resting area. The degree of aggregation of urination in the paddock, alley and resting area varied with the meteorological factors and the intake of supplement.

• 대한상한금궤의학회지
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• v.9 no.1
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• pp.59-73
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• 2017

Objectives : The purpose of this case report is to report the effect of Daesiho-tang on adult acne by Shanghanlun provisions with extrusion therapy. Methods : According to diagnostic system based on Shanghanlun provisions, the patient was diagnosed with Taeyang-byung Gyeolhyung and treated by Daesiho-tang with extrusion therapy. The result of administrations were evaluated by Korean Acne Grading System(KAGS), Korean Skindex-29, and change of clinical symptoms. Results : After administration of Daesiho-tang for 150 days with weelky extrusion therapy, KAGS improved from grade 4 to grade 1, Skindex-29 improved from 67.93 to 15.51, and patient was very satisfied with the treatment. No serius treatment-related adverse events were reported. Limitations : This case is only one case that the level of evidence is weak. Two interventions were used together and the duration of photo was uneven. Conclusions : The patient almost recovered from acne treated by Daesiho-tang according to diagnostic system based on Shanghanlun provisions with extrusion therapy. This is the first case report that suggests '熱結在裏' on the number 136 provision of Shanghanlun means fever that is always present in chronic skin lesions.

• Biomedical Science Letters
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• v.13 no.4
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• pp.361-368
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• 2007

Biological samples can be fixed either by chemical method by using chemical solution or physical methods by using heat treatment. The problem in traditional heat fixation is unsatisfactory quality due to uneven heat conduction in specimen and loss of inner cell contents. Chemical fixation method also bears several intrinsic problems like the limit in specimen size, time consumption in fixative impregnation, and loss of low molecular weight cell components. These factors deteriorate the quality of fixed specimen, thus limit the magnification and contrast of tissue pictures. Microwave heat has been reported to be a good alternative to current chemical methods to overcome these problem. In this study, we tried to introduce the microwave energy method to routine fixation work in hospital. We replaced chemical fixative with saline to provide moderate reaction condition, and used frozen section to reduce time for sample preparation. Temperature was measured at each experiment. The fixation of rat kidney tissue with 2.45 GHz electromagnetic wave and saline showed similar result to the control group fixed with traditional chemical method. Human tumor tissue fixed with 2.45 GHz electromagnetic in frozen section was improved in terms of histochemistry of PAS and immunohistochemistry of tumor marker like cytokeratin. Total turnaround time was reduced from $24\sim38$ h to to $2\sim4$ h. In conclusion, the quality of samples prepared by microwave heating method was at least as good as that of traditional method. If the condition for the fixation of different specimens is standardized, this new method could be applied to routine work in hospital, and could save working time as well.

• Korean Journal of Materials Research
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• v.26 no.11
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• pp.662-669
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• 2016

In order to identify changes in the nature of the particles due to changes in the inflow rate of the raw material solution, the present study was intended to prepare nano-sized cobalt oxide ($Co_3O_4$) powder with an average particle size of 50 nm or less by spray pyrolysis reaction using raw cobalt chloride solution. As the inflow rate of the raw material solution increased, droplets formed by the pyrolysis reaction showed more divided form and the particle size distribution was more uneven. As the inflow rate of the solution increased from 2 to 10 ml/min, the average particle size of the formed particles increased from about 25 nm to 40 nm, while the average particle size did not show significant changes when the inflow rate increased from 10 to 50 ml/min. XRD analysis showed that the intensity of the XRD peaks increased remarkably when the inflow rate of the solution increased from 2 to 10 ml/min. On the other hand, the peak intensity stayed almost constant when the inflow rate increased from 10 to 50 ml/min. With the increase in the inflow rate from 2 to 10 ml/min, the specific surface area of the particles decreased by approximately 20 %. On the contrary, the specific surface area stayed constant when the inflow rate increased from 10 to 50 ml/min.

• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.3
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• pp.207-210
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• 2000

When endothelial cells isolated isolated from human umbilical venis were cultred for 6dary using 96-well microplates, the final cell density in each was fiund not to be the same although the medium composition of each well was exactly the same. Cell growth in the wells located at the periphery of a microplate was low, while that in the central area of the plate was high. A possible cause for different rate of growth was proposed as the uneven concentration of oxygen in the culture medium of each well.

• Journal of Korean Society of Forest Science
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• v.94 no.5 s.162
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• pp.321-329
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• 2005

Based on the data representing four typical Korean pine forest types, the age structure, DBH distribution, species composition, and forking rule were systemically analyzed for old-growth Korean pine forest in Liangshui Nature Reserve, northeast China. The age structure of Korean pine trees was strongly uneven-aged with one dominated peak following normal distribution, and age of trees varied from 100 to 180 years within a stand. The DBH and height differences in same age class (20 years) varied from 28 cm~64 cm and 5 to 20 m, respectively. Many conifer and hard wood species, such as spruce, fir, costata birch, basswood, oak, and elm, were mixed with dominated trees of Korean pine. The canopy of the old-growth Korean pine forest can be divided into two layers, and differences of mean age and height between Layer I and Layer II were ranged 80~150 years and 7~13 m, respectively. The Weibull function was used to model the diameter distribution and performed well to describe size-class distribution either with a single peak in over-story canopy and inverse J-shape in under-story canopy for old-growth Korean pine stands. The forking height of Korean pine trees ranged from 16m to 24 m (mean 19.4 m) and tree age about 120 to 160 years old. The results will provide a scientific basis to protect and recover the ecosystem of natural old-growth Korean pine and also provide the model in management of Korean pine plantation.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.9 no.3
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• pp.21-30
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• 1989

In this study, the dynamic behavior of a continuous bridge under moving load is studied considering roughness of the road surface. Vehicle model includes the spring effects of axes, and due to these effects, equations of motions for the vehicle and bridge are derived in coupled form. And then iteration method is used to solve the equations. In experimental study a bridge model is constructed considering the similarity rule in order that the model exhibits dynamic behavior similar to that of prototype. Three types of roughness such as uneven random roughness, uplift on the approach and piece-wise constant roughness are used to describe road roughness. Through the numerical analysis and experiments, the effects of surface roughness, sprung mass, and velocity on the dynamic behavior of the bridge are examined.