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http://dx.doi.org/10.7314/APJCP.2014.15.2.537

Head and Neck Cancer: Global Burden and Regional Trends in India  

Mishra, Anupam (Department of Otolaryngology and Head and Neck, KG Medical University Lucknow)
Meherotra, Rohit (Rama Medical College)
Publication Information
Asian Pacific Journal of Cancer Prevention / v.15, no.2, 2014 , pp. 537-550 More about this Journal
Abstract
The actual burden of head and neck cancer in India is much greater than reflected through the existing literature and hence can be regarded as a 'tip of iceberg' situation. This has further been evident by the recent reports of 'Net-based Atlas of Cancer in India'. South-east Asia is likely to face sharp increases of over 75% in the number of cancer deaths in 2020 as compared to 2000. Since the percentage increase of Indian population has been nearly twice that of the world in last 15 years there is a likelihood of increase in cancer burden with the same proportion. The distribution of population based cancer registries is grossly uneven with certain important parts of the country being not represented at all and hence the current cancer burden is not reflected by registry data. However, the pathetic situation of health care system in major parts of the country as also emphasized by the World Bank, is not suitable to provide anywhere near accurate data on cancer burden. Head and neck cancer (including thyroid lesions) is third most common malignancy seen in both the sexes across the globe but is the commonest malignancy encountered in Indian males. Also oral cavity cancer is the most prevalent type amongst the males and one of the highest across the globe. This article reviews the latest global and national situation with an especial emphasis on head and neck cancer. Furthermore this review focuses on burden in different sub sites at national and global levels.
Keywords
Cancer; lip; tongue; oral cavity; oropharynx; nasopharynx; hypopharynx; larynx; thyroid; India;
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1 Takiar R, Vijay CR (2011). An alternative approach to study the changes in the cancer. Pattern of men in India (1988-2005). Asian Pac J Cancer Prev, 12, 875-8.
2 Sunny L, Yeole BB, Hakama M, et al. (2004). Oral cancers in Mumbai, India: a fifteen years perspective with respect to incidence trend and cumulative risk. Asian Pac J Cancer Prev, 5, 294-300.
3 Swaminathan R, Selvakumaran R, Esmy PO, et al. (2009). Cancer pattern and survival in a rural district in South, India. Cancer Epidemiol, 33, 325-31.   DOI   ScienceOn
4 Swederlow AJ, Marmot MG, Grulich AE, et al. (1995). Cancer mortality in Indian and British ethnic immigrants from the Indian sub-continent to England and Wales. Br J Cancer, 72, 1312-9.   DOI
5 Tomatis L, Aitio A, Day NE, et al. (1990). Cancer: causes, occurrence and control. IARC, 100, 1-368.
6 NRCP (2002). National Cancer registry Programme (NRCPICMR). Ten year consolidated report of the hospital based cancer registries 1994-98, Bangalore, 2002.
7 NRCP (2001). National Cancer registry Programme (NRCPICMR). Ten year consolidated report of the hospital based cancer registries 1984-93, Bangalore: NRCP 2001.
8 Pantvaidya GH, Vaidya AD, Metgudmath R, et al. (2012). Minor salivary gland tumors of the sinonasal region: results of a retrospective analysis with review of literature. Head Neck, 34, 1704-10.   DOI   ScienceOn
9 Parkin DM, Whelan SL, Ferlay J, et al. (1997). Cancer incidence in five continents volume VII (IARC Scientific Publication no. 143) Lyon : IARC 1997.
10 Parkin DM, Whelan SL, Ferlay J, Teppo L, Thomas DB (eds) (1997). Cancer Incidence in Five Continents (vol VIII). IARC, Scientific Publication no. 155, Lyon 1997 (ISBN 92 832 21 55 9).
11 Schottenfield D (1979). Alcohol as a co-factor in the etiology of cancer. Cancer, 43, 1962.   DOI
12 Rous GC, Walrath J, Stayner LT, et al. (1987). Nasopharngeal cancer, sinunasal cancer and occupation related to formaldehyde: a case control study. J Natl Cancer Inst, 76, 1221.
13 Sankaranarayanan R, Masuyer E, Swaminathan R, et al. (1998). Head and neck cancer: a global perspective on epidemiology and prognosis. Anticancer Res, 18, 4779-86.
14 Sarda AK, Kapur MM (1990). Thyroid Cancer. A report of 206 cases from an area with endemic goiter. Acta Oncol, 29, 863-7.   DOI   ScienceOn
15 Sharma P, Saxena S, Aggarwal P (2010). Trends in the epidemiology of oral squamous cell carcinoma in western UP: An institutional study. Indian J Dent Res, 21, 316-9.   DOI   ScienceOn
16 Sharma RG, Maheshwari MS, Lodha SC (1992). Cancer profile in western Rajasthan. Indian J cancer, 29, 126-35.
17 Shenoi R, Devrukhkar V, Chaudhuri, et al. (2012). Demographic and clinical profile of oral squamous cell carcinoma patients: a retrospective study. Indian J Cancer, 49, 21-6.   DOI
18 Stich HF, Curtis JR, Parida BB (1982). Application of the micronucleus test to exfoliated cells of high cancer risk groups: tobacco chewers. Int J Cancer, 30, 553-9.   DOI
19 Stocks P (1970). Cancer mortality in relation to national consumption of cigarettes, solid fuel, tea and coffee. Br J Cancer, 24, 215.   DOI   ScienceOn
20 Straif K, Weiland SK, Bungers M et al. (1999). Exposure to nitrosamines and mortality from salivary gland cancer among rubber workers. Epidemiology, 10, 786-7.   DOI
21 Wynder EL, Bross IJ, Day E (1956). Epidemiological approach to the etiology of the cancer of larynx. JAMA, 160, 1384.   DOI
22 Varma KD (1999). Thyroid cancer: Experiences at Uttar Pradesh. In: Thyroid Cancer - An Indian Perspective (ISBN-8187099054, 9788187099055), Eds. Shah D, Samuel AM, Rao RS. Quest Publication, 595.
23 WHO (2003). Concerted global action is the only answer to rising cancer deaths WHO 2003.
24 WHO-UICC (2003). Global Action Against Cancer, Publication of WHO (ISBN 92 4 1590726) 2003.
25 Yeole BB, Kurkure A, Advani S, et al. (2001). An assessment of cancer incidence patterns in parsi and non-parsi populations, greater Mumbai. Asia Pac J Cancer Prev, 2, 293-8.
26 Yeole BB, Kurkure AP, Sunny L (2011). Cancer survival in Mumbai (Bombay), India, 1992-1999. IARC Sci Publ, 162, 133-42.
27 Yoganathan P (2002). Betal chewing creeps into the new world, NZ Dent J, 98, 40-5.
28 Yu MC (1991). Nasopharyngeal carcinoma: Epidemiology and dietary factors. IARC Sci publication, 105, 39.
29 Zheng W, Shu XO, Ji BT, et al. (1996). Diet and other risk factors for cancer of the salivary glands: a population based case control study, Int J Cancer, 67, 194-8.   DOI
30 Zinyu R, Kumar S, Dutta LP (1990). Studies on cancer of nasopharynx in Nagaland India. Proceedings of the XIV world congress of otorhinolaryngology and Head and Neck Surgery. Eds Sacriston T. Kugler and Ghedini Publications, Amsterdam 1990; pg 1279.
31 Rooban T, Elizabeth J, Umadevi KR et al. (2010). Sociodemographic correlates of male chewable smokeless tobacco users in India: a preliminary report of analysis of National Family Health Survey, 2005-2006. Indian J Cancer, 1, 91-100.
32 Banerjee AK, Bhattacharya N, Chaudhary MK, et al. (1994). Incidence of malignancy in Bankura (a retrospective study). J Indian Med Assoc, 92, 400-2.
33 Agrawal M, Pandey S, Jain S, et al. (2012). Oral cancer awareness of the general public in Gorakhpur City, India. Asian Pac J Cancer Prev, 13, 5195-9.   과학기술학회마을   DOI   ScienceOn
34 Armstrong RW, Armstrong MJ, Yu MC, et al. (1983). Salted fish and inhalants as risk factors for nasopharyngeal carcinoma in Malaysian Chinese. Cancer Res, 43, 2967.
35 Atlas of Cancer in India (2005). HTTP:www.canceratlasindia. org/chapter6_Report.asp?SiteName=Mout&ReportType=Dist_.
36 Barton RT (1977). Nickle carcinogenesis of the respiratory tract. J Otolaryngol, 6, 412.
37 Bisht M, Bisht SS (2011). Human papilloma virus: a new risk factor in a subset of head and neck cancers. J Cancer Res Ther, 7, 251-5.   DOI   ScienceOn
38 BSAA (2004). Bureau of South Asian Affairs, Background: India, US department of state Nov 2004.
39 Byakodi R, Byakodi S, Hiremath S, et al. (2012). Oral cancer in India: an epidemiologic and clinical review. J Community Health, 37, 316-9.   DOI
40 Chakravarty I, Ghosh K (2000). Micronutrient malnutrition present status and future remedies. J Indian Med Assoc, 98, 539-42.
41 Tondon M, Kapil U, Bahadur S, et al. (2000). Role of micronutrients and trace elements in carcinoma of larynx. J Assoc Physicians India, 48, 995-8.
42 Tsai CC, Chen CL, Hsu HC (1996). Expression of Epstein-Barr virus in carcinoma of major salivary glands: a strong association with lymphoepithelioma like carcinoma. Hum Pathol, 27, 258-62,   DOI   ScienceOn
43 Vaidya AD, Pantvaidya GH, Metgudmath R, et al. (2012). Minor salivary gland tumors of the oral cavity: a case series with review of literature. J Cancer Res Ther, 1, 111-5.
44 Acheson ED, Cowdell RH, Hadfield E, Macbeth RG (1968). Nasal cancers in wood workers in furniture industry. Br Med J, 2, 587.   DOI
45 Actis AB, Eynard AR (2000). Influence of environmental and nutritional factors on salivary gland tumorigenesis with a special reference to dietary lipids. Eur J Clin Nutr, 54, 805-10.   DOI   ScienceOn
46 Agarwal A, Mishra SK (1997). Iodine deficiency and thyroid cancer. In: a monograph on thyroid cancer, Eds. Saroj K Mishra. JICA, 7-10.
47 Hiranandani LH (1975). Panel on epidemiology and etiology of laryngeal carcinoma. Laryngoscope, 85, 1197.   DOI   ScienceOn
48 Horn-Ross PL, Morrow M, Ljung BM (1999). Menstrual and reproductive factors for salivary gland cancer risk in women. Epidemiology, 10, 528-30.   DOI   ScienceOn
49 Hu MS, Huang HL (1972). Retrospective study on etiological factors of nasopharyngeal carcinoma. New Med (Canton), 12, 10.
50 Engeland A, Bjorge T, Haldorsen T, et al. (1997). Use of multiple primary cancers to indicate association between smoking and cancer incidence: an incidence of 500,000 cancer cases diagnosed in Norway during 1953-93. Int J Cancer, 70, 401-7.   DOI
51 Dikshit R, Gupta PC, Ramasundarahettige C, et al. (2012). Million death study collaborators. Cancer mortality in India: a nationally representative survey. Lancet, 379, 1807-16.   DOI   ScienceOn
52 Franceschi S, Bidoli E, Herrero R, et al. (2000). Comparison of cancers of the oral cavity and pharynx world wide: etiological clues. Oral Oncol, 36, 106-15.   DOI   ScienceOn
53 Dikshit RP, Kanhare S (1999). Cancer patterns of lung, oropharynx and oral cavity cancer in relation to gas exposure at Bhopal. Cancer Causes and Control, 10, 627-36.   DOI   ScienceOn
54 Elango JK, Sundaram KR, Gangadharan P, et al. (2009). Factors affecting oral cancer awareness in a high-risk population in India. Asian Pac J Cancer Prev, 10, 627-30.
55 Ferlay J, Parkin DM, Pisani P (1998). GLOBOCAN Cancer incidence and mortality world wide. IARC Cancer base 3 (on CD ROM). Lyon: IARC.
56 Hebert JR, Gupta PC, Bhonsle RB, et al. (2002). Dietary exposures and oral precancerous lesions in Srikakulam district, Andhra Pradesh India. Public Health Nutr, 5, 303-12.
57 Heck JE, Sapkota A, Vendhan G, et al. (2008). Dietary risk factors for hypopharyngeal cancer in India. Cancer Causes Control, 19, 1329-37.   DOI
58 Hildesheim A, West S, De Veyra E, et al. (1992). Herbal medicine use , Epstein Barr virus, and risk of nasopharyngeal carcinoma. Cancer Res, 52, 3048.
59 Kumar S, Heller RF, Pandey U, et al. (2001). Delay in presentation of oral cancer: a multifactorial analytical study. Natl Med J India, 14, 13-7.
60 Koppikar P, deVilliers EM, Mulherkar R (2005). Identification of human papilloma viruses in tumours of the oral cavity in an Indian community. Int J Cancer, 113, 946-50.   DOI   ScienceOn
61 Kotaki AC, Simons MJ, Das AK, et al. (2011). Nasopharyngeal carcinoma in the Northeastern states of India. Chinese J Cancer, 30, 106-13.   DOI
62 Clifford P (1970). A review on the epidemiology of nasopharyngeal carcinoma. Int J Cancer, 5, 287.   DOI
63 Kulkarni SS, Kulkarni SS, Vastrad PP, et al. (2011). Prevalence and distribution of high risk human papillomavirus (HPV) types 16 and 18 in carcinoma of cervix, saliva of patients with oral squamous cell carcinoma and in the general population in Karnataka, India. Asian Pac J Cancer Prev, 12, 645-8.
64 Kumar S, Mahanta J (1998). Aetiology of nasopharyngeal carcinoma. A review. Indian J Cancer, 35, 47-56.
65 Chelleng PK, Narain K, Das HK, et al. (2000). Risk factors for nasopharyngeal carcinoma: a case control study form Nagaland India. Natl Med J India, 13, 6-8.
66 Clifford P, Bulbrook RD (1967). Environmental studies in African males in nasopharyngeal carcinoma. Lancet, 1, 1228.
67 Cox SC, Walker DM (1996). Oral submucous fibrosis. Aust Dent J, 41, 294-9.   DOI   ScienceOn
68 De Stefani E, Correa P, Oreggia F, et al. (1987). Risk factors for laryngeal cancer. Cancer, 60, 3087,   DOI
69 Dhar GM, Shah GN, Naheed B, et al. (1993). Epidemiological trend in the distribution of cancer in Kashmir valley. J Epidemiol Community Health, 47, 290-2.   DOI
70 Kalyani R, Das S, Kumar MLH (2010). Pattern of cancer in adolescent and young adults - a ten year study in India. Asian Pac J Cancer Prev, 11, 655-9
71 Jacob BJ, Straif K, Thomas G, et al. (2004). Betal quid without tobacco as a risk factor for oral precancers. Oral Oncol, 40, 697-704.   DOI   ScienceOn
72 Katz AD, Preston-Martin S (1984). Salivary gland tumours and previous radiotherapy to head and neck: report of a clinical series. Am J Surg, 147, 345.   DOI   ScienceOn
73 Jalouli J, Jalouli MM, Sapkota D, et al. (2012). Human papilloma virus, herpes simplex virus and epstein barr virus inoral squamous cell carcinoma from eight different countries. Anticancer Res, 32, 571-80.
74 Kapil U, Singh P, Bahadur S, et al. (2003). Association of vitamin A, vitamin C and zinc with laryngeal cancer. Indian J Cancer, 40, 67-70.
75 Kapoor R, Goswami KC, Kapoor B, et al. (1993). Pattern of cancer in Jammu region (Hospital based study 1978-87). Indian J Cancer, 30, 67-71.
76 Khuroo MS, Zargar SA, Mahajan R, et al. (1992). High Incidence of esophageal and gastric cancers in Kashmir in a population of special personal and dietary habits. Gut, 33, 11-5.   DOI   ScienceOn
77 Kissin B, Kaley MM, Su WH, et al. (1973). Head and neck cancer in alcoholics. The relationship to drinking, smoking and dietary patterns. JAMA, 224, 1174.   DOI   ScienceOn
78 Klitenberg C, Olofson J, Hellquist H, et al. (1984). Adenocarcinoma of ethmoid sinuses: a review of 28 cases with special reference to wood dust exposure. Cancer, 54, 482.   DOI
79 Moore SR, Johnson NW, Pierce AM, et al. (2000). The epidemiology of mouth cancer: a review of global incidence. Oral Dis, 6, 65-74.
80 Mishra A, Verma V (2012). Oral Sex and HPV: population based indications. Indian J Otolaryngol Head Neck Surg, 1-7.
81 Mohan A (2005). UP's Health system riddled with quacks (State of UP's economy). The Times of India daily Lucknow edition 27th June 2005, page 4.
82 Murthy NS, Juneja A, Sehgal A, et al. (1990). Cancer projection by the turn of century - Indian scene. Ind J cancer, 27, 74-82.
83 Molnar L, Ronay P, Tapolcsanyi L (1974). Carcinoma of the lip: analysis of the materials of 25 years. Oncology, 29, 101.   DOI
84 Morgan RW, Shettigara PT (1976). Occupational asbestos exposure, smoking and laryngeal carcinoma. Ann NY Acad Sci, 271, 308-10.   DOI   ScienceOn
85 Murthy NS, Chaudhry K, Rath GK (2008). Burden of cancer and projections for 2016, Indian scenario: Gaps in the availability of radiotherapy treatment facilities. Asian Pac J Cancer Prev, 9, 671-7.
86 Nair MK, Sankarnarayanan R, Padmanabhan TK (1988). Clinical profile of 2007 oral cancers in Kerela, India. Ann Dent, 47, 23-6.
87 Nandakumar A, Gupta PK, Gangadharan P, et al. (2005). Epidemiology, Geographic pathology revisited: development of an atlas of cancer in India. Int J Cancer, 116, 740-54.   DOI   ScienceOn
88 ICMR (2001). National Cancer Registry Programme, consolidated report of the population based cancer registries incidence and distribution of cancer 1990-96, Bangalore NRCP 2001.
89 Iype EM, Pandey M, Mathew A et al. (2004). Squamous cell cancer of the buccal mucosa in young adults. Br J Oral Maxillofac Surg, 42, 185-9.
90 Kumar V KV, Suresan V (2012). Knowledge, attitude and screening practices of general dentists concerning oral cancer in Bangalore city. Indian J Cancer, 49, 33-8.   DOI
91 Nayar D, Kapil U, Joshi YK, et al. (2000). Nutritional risk factors in esophageal cancers. J Assoc Physicians India, 48, 781-7.
92 NCCP (2006). National cancer control program.
93 Malhotra V, Shah BS, Sabharwal S (2001). Pattern of cancer in Dayanand Medical College and Hospital, Ludhiyana (a ten year retrospective study). Indian J Pathol Microbiol, 44, 27-30.
94 Kumar S, Zinyu R, Singh IKK, et al. (1996). Studies on nasopharyngeal carcinoma with reference to the north eastern region of India. Ann Natl Acad Med Sci, 32, 199.
95 Kurozumi S, Harada Y, Sugimoto Y, et al. (1977). Airway malignancy in poisonous gas workers. Laryngol Otol, 91, 217.   DOI   ScienceOn
96 Lowry WS (1975). Alcoholism in cancer of head and neck. Laryngoscope, 85, 1275.   DOI   ScienceOn
97 Malkan G, Mohandas KM (1997). Epidemiology of digestive cancers in India. I. General principles and esophageal cancer. Indian J Gastroenterol, 16, 98-102.
98 Manoharan N, Tyagi BB, Raina V (2010). Cancer incidence in rural Delhi. Asia Pac J Cancer Prev, 11, 73-8.
99 Mehrotra R, Singh M, Kumar D, et al. (2003). Age specific incidence rate and pathological spectrum of oral cancer in Allahabad. Indian J Med Sciences, 57, 400-4.
100 Mehta FS, Bhonsle RB, Murti PR, et al. (1989). Central papillary atrophy of the tongue among bidi smokers in India: a 10 years study of 182 lesions. J Oral Pathol Med, 18, 475-80.   DOI   ScienceOn
101 Merrick Y, Albeck H, Nielsen NH, et al. (1986). Familial clustering of salivary gland carcinoma in Greenland. Cancer, 57, 2097   DOI
102 Pillai MR, Nair MK, Kannan S, et al. (1993). Immunopathological and immunological features of oral precancers. Singapore Dent J, 18, 28-38.
103 Pinkston JA, Cole P (1996). Cigarette smoking and Warthin's tumour. Am J Epidemiol, 114, 183-7.
104 Patel PS, Raval GN, Patel DD, et al. (2001). A study of various sociodemographic factors and plasma vitamin levels in oral and pharyngeal cancer in Gujarat, India. Asian Pac J Cancer Prev, 2, 215-24.
105 Paulose KP (2011). Hypothyroidism in Kerela (editorial). Kerela Med J, 11, 139-40.
106 Phukan RK, Chetia CK, Ali MS, et al. (2001). Role of dietary habits in the development of esophageal cancer in Assam, the north eastern region of India. Nutr Cancer, 39, 204-9.   DOI   ScienceOn
107 Rajkumar T, Sridhar H, Balaram P, et al. (2003). Oral cancer in Southern India: the influence of body size, diet infections and sexual practices. Eur J Cancer Prev, 12, 135-43.   DOI   ScienceOn
108 Rao DN (1999). Epidemiological observations. In Shah D, Samuel AM, Rao RS (Eds) thyroid cancer: an Indian perspective. Mumbai, Quest Publications, 3-16.
109 Rathaur RG, Chitale AR, Banerjee K (1999). Epstein Barr virus in nasopharyngeal carcinoma in Indian patients. Indian J Cancer, 36, 80-90.
110 Raybaud H, Odin G, Fafet A, et al. (2003). Genetic alterations in oral and head and neck squamous cell carcinoma: analysis of international literature. Pathol Biol, 51, 176-84.   DOI   ScienceOn
111 Reddy CR (1974). Carcinoma of hard palate in India in relation to reverse smoking of 'chuttas'. J Natl Cancer Inst, 53, 615-9.
112 Ron E, Lubin JH, Shore RE, et al. (1995). Thyroid cancer after exposure to external radiation - A pooled analysis of seven studies. Radiat Res, 141, 259-77.   DOI   ScienceOn
113 Siddiqi M, Kumar R, Fazili Z, et al. (1992). Increased exposure to dietary amines and nitrate in a population at a high risk of esophageal and gastric cancers in Kashmir (India). Carcinogenesis, 13, 1331-5.   DOI   ScienceOn
114 Franceschi S, Levi F, La Vecchia C, et al. (1999). Comparison of the effect of smoking and alcohol drinking between oral and pharyngeal cancer. Int J Cancer, 83, 1-4.   DOI
115 Jayant K, Nene BM, Dinshaw KA, et al. (2011). Cancer survival in Barshi, India, 1993-2000. IARC Sci Publ, 162, 101-6.