• Title/Summary/Keyword: Understanding of Humans

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State of the Art of Taenia solium as Compared to Taenia asiatica

  • Flisser, Ana
    • Parasites, Hosts and Diseases
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    • v.51 no.1
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    • pp.43-49
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    • 2013
  • Three species of tapeworms infect humans in their adult stage (Taenia solium, Taenia saginata and Taenia asiatica). The 3 are flat, opaque white or yellowish, and exceptional long segmented parasites, measuring 1 to 12 m in their adult stage. In this review, the development of the knowledge regarding the first species, mainly focused on understanding how the larval stage or cysticercus is transmitted to humans, is described. The second species is a cosmopolitan parasite that only causes taeniosis and not cysticercosis; therefore, it will not be included. Information on the third species, which is presently being produced, since this species was recognized as such only at the end of the 20th century, will be discussed at the end of this review.

Predicting tissue-specific expressions based on sequence characteristics

  • Paik, Hyo-Jung;Ryu, Tae-Woo;Heo, Hyoung-Sam;Seo, Seung-Won;Lee, Do-Heon;Hur, Cheol-Goo
    • BMB Reports
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    • v.44 no.4
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    • pp.250-255
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    • 2011
  • In multicellular organisms, including humans, understanding expression specificity at the tissue level is essential for interpreting protein function, such as tissue differentiation. We developed a prediction approach via generated sequence features from overrepresented patterns in housekeeping (HK) and tissue-specific (TS) genes to classify TS expression in humans. Using TS domains and transcriptional factor binding sites (TFBSs), sequence characteristics were used as indices of expressed tissues in a Random Forest algorithm by scoring exclusive patterns considering the biological intuition; TFBSs regulate gene expression, and the domains reflect the functional specificity of a TS gene. Our proposed approach displayed better performance than previous attempts and was validated using computational and experimental methods.

Ecological Features appearing in Korean Traditional Architecture and Landscape Architecture (한국 전통건축과 랜드스케이프 건축에 나타난 생태학적 특성)

  • Lee, Young-Mi;Cheon, Deuk-Youm
    • Journal of architectural history
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    • v.14 no.4 s.44
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    • pp.101-115
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    • 2005
  • The main aim of this research is centered on the relation between nature and humans, and is to study the ecological characteristics appearing both in Landscape Architecture, one of the currents of ecological architecture as the architectural solution on the relation between humans and nature, and in our traditional architecture. Through this study, we were able to see that our traditional architecture was influenced by our ancestor's view of nature, and that the foremost feature of our ancestor's view of nature on our traditional architecture is not conflicting with nature, but, instead it is complying with it through seeking harmony with nature. Also we could see that our ancestor's view of nature is similar to Landscape Architecture having come to the fore toward the tendency of modern ecological paradigm in that it is the representation seeking the organic view of nature pursuing the oneness among artificial structure, humans, and nature. That is, we could figure out that various ecological features appearing in modem Landscape Architecture had been represented for a long long time, in a natural fashion, In the manner of space makeup in our traditional architecture. This is the characteristic of our ecological thinking system understanding nature and humans at the same context, and it has come down not only to our everyday living but to the manner of architectural solutions as well. Through this research, we could reconsider the modern value of ecological architecture inherent in our traditional architecture.

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On-Line Two-Dimensional Conducting Motion Analysis (실시간 이차원 지휘운동의 해석)

  • ;;;Zeung nam Bien
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.28B no.11
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    • pp.876-885
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    • 1991
  • This paper proposes an on-line method of understanding humans conducting action observed through a vision sensor. The vision system captures images of conducting action and extracts image coordinates of endpoint of the baton. A proposed algorithm based on the expert knowledge about conducting recognizes patterns of the conducting action from the extracted image coordimates and play the corresponding music score. Complementary algorithms are also proposed for identifying the first beat static point and dynamics through extensive experiments, this algorithm is found to detect lower edges and upper edges without error.

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Surgical Complications Affecting the Early and Late Survival Rates after Lung Transplantation

  • Suh, Jee Won
    • Journal of Chest Surgery
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    • v.55 no.4
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    • pp.332-337
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    • 2022
  • Since the first lung transplantation in humans was performed in 1963, patient selection, standardized procurement, and surgical techniques have been developed and established for this procedure. However, despite these developments, surgical complications continue to be important factors influencing patient morbidity and mortality, and efforts should be made to decrease morbidity and improve survival rates by understanding, rapidly detecting, and appropriately treating surgical complications.

Understanding the Host Innate Immune Responses against SARS-CoV-2 Infection and COVID-19 Pathogenesis

  • Yeon-Woo Kang;Subin Park;Kun-Joo Lee;Dain Moon;Young-Min Kim;Seung-Woo Lee
    • IMMUNE NETWORK
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    • v.21 no.1
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    • pp.1.1-1.16
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    • 2021
  • The emergence of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has become a significant health concern worldwide. Undoubtedly, a better understanding of the innate and adaptive immune responses against SARS-CoV-2 and its relationship with the coronavirus disease 2019 (COVID-19) pathogenesis will be the sole basis for developing and applying therapeutics. This review will summarize the published results that relate to innate immune responses against infections with human coronaviruses including SARS-CoV-1 and SARS-CoV-2 in both humans and animal models. The topics encompass the innate immune sensing of the virus to the dysregulation of various innate immune cells during infection and disease progression.

Normal and Disordered Formation of the Cerebral Cortex : Normal Embryology, Related Molecules, Types of Migration, Migration Disorders

  • Lee, Ji Yeoun
    • Journal of Korean Neurosurgical Society
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    • v.62 no.3
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    • pp.265-271
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    • 2019
  • The expansion and folding of the cerebral cortex occur during brain development and are critical factors that influence cognitive ability and sensorimotor skills. The disruption of cortical growth and folding may cause neurological disorders, resulting in severe intellectual disability and intractable epilepsy in humans. Therefore, understanding the mechanism that regulates cortical growth and folding will be crucial in deciphering the key steps of brain development and finding new therapeutic targets for the congenital anomalies of the cerebral cortex. This review will start with a brief introduction describing the anatomy of the brain cortex, followed by a description of our understanding of the proliferation, differentiation, and migration of neural progenitors and important genes and molecules that are involved in these processes. Finally, various types of disorders that develop due to malformation of the cerebral cortex will be discussed.

Genetic approaches toward understanding the individual variation in cardiac structure, function and responses to exercise training

  • Kim, Minsun;Kim, Seung Kyum
    • The Korean Journal of Physiology and Pharmacology
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    • v.25 no.1
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    • pp.1-14
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    • 2021
  • Cardiovascular disease (CVD) accounts for approximately 30% of all deaths worldwide and its prevalence is constantly increasing despite advancements in medical treatments. Cardiac remodeling and dysfunction are independent risk factors for CVD. Recent studies have demonstrated that cardiac structure and function are genetically influenced, suggesting that understanding the genetic basis for cardiac structure and function could provide new insights into developing novel therapeutic targets for CVD. Regular exercise has long been considered a robust nontherapeutic method of treating or preventing CVD. However, recent studies also indicate that there is inter-individual variation in response to exercise. Nevertheless, the genetic basis for cardiac structure and function as well as their responses to exercise training have yet to be fully elucidated. Therefore, this review summarizes accumulated evidence supporting the genetic contribution to these traits, including findings from population-based studies and unbiased large genomic-scale studies in humans.

An Analysis of Science-gifted Elementary School Students' Ontological Understanding of 'Living Things' (초등 과학영재학생들의 '살아있는 것'에 대한 존재론적 이해 분석)

  • Kim, Dong-Ryeul
    • Journal of Korean Elementary Science Education
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    • v.34 no.2
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    • pp.164-182
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    • 2015
  • This study aims to analyze science-gifted elementary students' understanding of 'Living Things' with ontological domains. As research subjects, this study selected 80 science-gifted students who belonged to Education Institute for Science-gifted Elementary Students at University of Education, and this study came to the following conclusions. Firstly, the gifted students thought of animals as living things most, out of which humans accounted for the highest rate. They were also found to evaluate the importance of living things depending on benefits and harms to humans. Secondly, when judging 4 domains of living things, animals, plants, static inanimate objects and dynamic inanimate objects, the gifted students did not have difficulty judging animals, plants and static inanimate objects, but 4 of them judged the moon, a dynamic inanimate object, as a living thing. In the aspect of reaction time, they spent more time judging plants than animals. This study classified their standards of judgement on living things into ontological categories. As a result, it was found that 31 and 33 out of them had standards of judgement corresponding to the category of matter and the category of process respectively, and only 16 of them had standards of judgement corresponding to the category of mental states. Thirdly, how to make a waterwheel and images of euglena and paramecium were shown to 10 of the gifted students who suggested simple movements as characteristics of living things. As a result, 7 of them changed their standards of judgement from the category of matter to the category of process, while 3 of them changed from the category of matter to the category of mental states.

The perspective on humans in a view of Oriental Medicines - discussion based mainly on Dongeuibogam - (한의학적(韓醫學的) 인간관(人間觀) -『동의보감(東醫寶鑑)』을 중심으로-)

  • Park, Sung Kyu;Cha, Wung-Seok;Kim, Nam Il
    • The Journal of Korean Medical History
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    • v.21 no.2
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    • pp.13-28
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    • 2008
  • Medical Science in general is a study dedicated to human. It is important to understand how human is being seen in medical science. The difference of this perspective among various medical science in different parts of the world shows the difference in ways of understanding human, and furthermore, difference in ways of understanding diseases. On the other side, Oriental Medicines tends to perceive human as a whole. Heo Joon's perspective on human is elaborated in his book, Dongeuibogam. The foundation of this perspective is found is the Thesis of Four Generals and Five Constants, Neijing. There are many discussions in the Thesis of Four Generals and Five Constants, which include the thesis of correspondence between nature and human: which define the relationship between human and nature in terms of four generals and five constants, and the thesis of xing and color: which offers the tool of making diagnosis on Four Generals and Five Constants, since xing and color designates the result of Four Generals and Five Constants. Other methods are also merely ways of expressing Four Generals and Five Constants in different angle. After all, the perspective of human shown by Heo Joon can be explained in one word as the thesis of Four Generals and Five Constants, and the principles of its theory, which are the thesis of correspondence between nature and human and the thesis of xing and color are also nothing more than a tool of underatanding Four Generals and Five Constants more efficiently.

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