• 제목/요약/키워드: Umbelliferae

검색결과 173건 처리시간 0.027초

미나리 지상부에서 라디칼 소거 활성을 가지는 페놀성 화합물의 분리 (Antioxidant Activity and Phytochemical Study on the Aerial Parts of Oenanthe javanica)

  • 조현우;이승호;남두현;김종연;임상규;이정수;박종철
    • 생약학회지
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    • 제39권2호
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    • pp.142-145
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    • 2008
  • Five compounds were isolated from the methanol extract of the aerial parts of Oenanthe javanica(Umbelliferae). Their chemical structures were identified as isorhamnetin(1), uracil(2), adenosine(3), persicarin(4) and uridine(5) by comparison of their spectral data with those of authentic samples and compounds 2, 3 and 5 were isolated from Oenanthe javanica for the first time. Compound 1 showed the strong radical scavenging activity among the compounds isolated from Oenanthe javanica.

기름나물 과실의 Coumarin성분 연구 (II) (Studies on the Coumarins of the fruits of Peucedanum terebinthaceum Fisher et Turcz)

  • 육창수;김현숙;김정태
    • 약학회지
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    • 제30권2호
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    • pp.73-78
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    • 1986
  • Peucedanum terebinthaceum Fischer (Umbelliferae) known as "Gi Reum Na Mool" in Korea and used for the treatment of cough, phlegm, headache and common cold etc. The substances were isolated from the fruits of Peucedanum terebinthaceum and identified by UV, GLC, IR, NMR, Mass spectra and physico-chemical tests. The steroidal compounds from the fruits were identified as $\beta$-sitosterol (tR 33.01 min.) and stigmasterol (tR 28.87 min.) by GLC. Substance I (colorless prismatic crystal, $C_{19}H_{20}O_5$, mp $110~111^{\circ}$) was identified as decursin which is one of the pyranocoumarin. Hydrolysis of substance I with 5%-potassium hydroxide produced decursinol. Acetylation of decursinot gave its monoacetate, white needles, $C_{16}H_{16}O_5$. Substance II(light yellowish white needle crystal, $C_9H_6O_3$, mp $227~228^{\circ}$) was proved to be umbelliferone. Substance I, decursin, was isolated for the first time from the fruits of Peucedanum spp. (Umbelliferae).

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Guaiane Sesquiterpenoids from Torilis japonica and Their Cytotoxic Effects on Human Cancer Cell Lines

  • Park Hye Won;Choi Sang-Un;Baek Nam-In;Kim Sung-Hoon;Eun Jae Soon;Yang Jae Heon;Kim Dae Keun
    • Archives of Pharmacal Research
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    • 제29권2호
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    • pp.131-134
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    • 2006
  • A new compound 2 and two known guaiane-type sesquiterpenoids were isolated from the methylene chloride-soluble fraction of the methanolic extract of the fruits of Torilis japonica (Umbelliferae) through repeated silica gel and Sephadex LH-20 column chromatography. Their chemical structures were elucidated as torilin (1), 11-acetoxy-8-angeloyloxy-$1{\beta}$-hydroxy-4-guaien-3-one ($1{\beta}$-hydroxytorilin, 2), and 11-acetoxy-8-angeloyloxy-$1{\alpha}$-hydroxy-4-guaien-3-one ($1{\alpha}$-hydroxytorilin, 3) by spectroscopic analysis. Compounds 1-3 exhibited cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.

한국산 산형과 식물의 성분연구 -Decursin, Decursinol 및 Nodakenin 의 일반약리작용- (Studies on the Components of Umbelliferae Plants in Korea -Pharmacological Study of Decursin, Decursinol and Nodakenin-)

  • 지형준;김학성
    • 생약학회지
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    • 제1권1호
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    • pp.25-32
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    • 1970
  • Decursin, decursinol and nodakenin which were isolated from the root of Angelica gigas $N_{AKAI}$ (Umbelliferae) that is used as a botanical drug Dang-Gui (當歸) in Korea show following general pharmacologic activities. Decursin and decursinol increased the motility of the excised duodenum of the rabbit, but nodakenin did not. All of these three compounds depressed the heart contraction of the frog and blood pressure of the carotid artery and respiration of the rabbit. Decursin increased uterus contraction of the rabbit, but decursinol depressed it. And the tonus of the muscle of the earth worm was increased by decursinol, but was decreased by decursin.

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Isolation and Structure Determination of Coumarin Derivatives from the Roots of Angelica dahurica

  • Kim, Ji-Yeon;Son, Jong-Keun;Song, Dong-Keun
    • Journal of Evidence-Based Herbal Medicine
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    • 제3권1호
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    • pp.35-41
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    • 2010
  • From the roots of Angelica dahurica Bentham et Hooker (Umbelliferae), three known coumarin derivatives have been isolated and identified as 8-(2-hydroxy-3-methoxy-3-methylbutyloxy) psoralen, 5,8-di(2,3-dihydroxy-3-methylbutyloxy) psoralen, 9-[3-($\beta$-D-glucopyranosyloxy)-2-hydroxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one. This is the first report of the occurrence of these compounds in this plant. These three compounds were tested for activity in septic shock model. Among these compounds, 2 showed relatively strong preventive activity against septic shock.

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Angelica속 생약의 정유성분에 관한 연구(V) -바디나물의 정유성분- (Studies on Essential Oils of Plants of Angelica Genus in Korea(V) -Essential Oils of the Root of Angelica decursiva-)

  • 지형준;김현수
    • 생약학회지
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    • 제24권3호
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    • pp.192-196
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    • 1993
  • Essential oil of the root of Angelica decursiva(Miq.) Fr. et Sav. (Umbelliferae) was investigated. Essential oil was obtained from the dried roots by steam distillation and fractionated by column chromatography. Each isolate or fraction was identified by GC, GC-MS and spectral analysis. It was found to contain ten monoterpenes such as ${\alpha}-pinene$ (7.0%) etc. Three hydrocarbons, two aldehydes, three sesquiterpenes, two sesquiterpene alcohols, one aromatic compounds, one ketone, isobonyl acetate and two lactones were tentatively identified.

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Ethnobotany, Phytochemistry, and Pharmacology of Angelica decursiva Fr. et Sav.

  • Ali, Md Yousof;Seong, Su Hui;Jannat, Susoma;Jung, Hyun Ah;Choi, Jae Sue
    • Natural Product Sciences
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    • 제25권3호
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    • pp.181-199
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    • 2019
  • Angelica decursiva Fr. et Sav. (Umbelliferae) has traditionally been used to treat different diseases due to its antitussive, analgesic, and antipyretic activities. It is also a remedy for thick phlegm, asthma, and upper respiratory infections. Recently, the leaf of A. decursiva has been consumed as salad without showing any toxicity. This plant is a rich in different types of coumarin derivatives, including dihydroxanthyletin, psoralen, dihydropsoralen, hydroxycoumarin, and dihydropyran. Its crude extracts and pure constituents possess anti-inflammatory, anti-diabetic, anti-Alzheimer disease, anti-hypertension, anti-cancer, antioxidant, anthelmintic, preventing cerebral stroke, and neuroprotective activities. This valuable herb needs to be further studied and developed not only to treat these human diseases, but also to improve human health. This review provides an overview of current knowledge of A. decursiva metabolites and their biological activities to prioritize future studies.

한국 미기록 귀화식물: 전호아재비(산형과)와 봄나도냉이(십자화과) (Two new naturalized species from South Korea, Chaerophyllum tainturieri Hook. (Umbelliferae) and Barbarea verna (Mill.) Asch. (Cruciferae))

  • 홍정기;박수현;이유미;오승환;정수영;이봉식
    • 식물분류학회지
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    • 제42권2호
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    • pp.171-177
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    • 2012
  • 한반도 미기록식물인 Chaerophyllum tainturieri Hook. (산형과)와 Barbarea verna (Mill.) Asch. (십자화과) 2종을 서울과 부산에서 각각 발견하였다. 전호아재비로 이름붙인 C. tainturieri는 서울 상암동의 월드컵공원에서 확인되었다. Chaerophyllum속은 국내에서는 처음으로 본 연구에서 보고되는 미기록속이다. 형태적 유사종인 무산상자속(Sphallerocarpus Besser ex DC.) 식물과 비교하여 열매가 통모양이고, 분과의 갈라지는 틈에 1개의 유관이 있다는 특징으로 구별된다. 봄나도냉이로 이름붙인 Barbarea verna는 부산 금사동의 수영강 둔치에서 확인되었으며, 동속 식물인 나도냉이(B. orthoceras)와는 근생엽의 길이가 4-8 cm이고, 근생엽이 4-11쌍으로 갈라지며, 종자의 길이는 1-2 mm라는 특징으로 구별된다.