• Korean Journal of Pharmacognosy
• /
• v.39 no.2
• /
• pp.142-145
• /
• 2008

Five compounds were isolated from the methanol extract of the aerial parts of Oenanthe javanica(Umbelliferae). Their chemical structures were identified as isorhamnetin(1), uracil(2), adenosine(3), persicarin(4) and uridine(5) by comparison of their spectral data with those of authentic samples and compounds 2, 3 and 5 were isolated from Oenanthe javanica for the first time. Compound 1 showed the strong radical scavenging activity among the compounds isolated from Oenanthe javanica.

• YAKHAK HOEJI
• /
• v.30 no.2
• /
• pp.73-78
• /
• 1986

Peucedanum terebinthaceum Fischer (Umbelliferae) known as "Gi Reum Na Mool" in Korea and used for the treatment of cough, phlegm, headache and common cold etc. The substances were isolated from the fruits of Peucedanum terebinthaceum and identified by UV, GLC, IR, NMR, Mass spectra and physico-chemical tests. The steroidal compounds from the fruits were identified as $\beta$-sitosterol (tR 33.01 min.) and stigmasterol (tR 28.87 min.) by GLC. Substance I (colorless prismatic crystal, $C_{19}H_{20}O_5$, mp $110~111^{\circ}$) was identified as decursin which is one of the pyranocoumarin. Hydrolysis of substance I with 5%-potassium hydroxide produced decursinol. Acetylation of decursinot gave its monoacetate, white needles, $C_{16}H_{16}O_5$. Substance II(light yellowish white needle crystal, $C_9H_6O_3$, mp $227~228^{\circ}$) was proved to be umbelliferone. Substance I, decursin, was isolated for the first time from the fruits of Peucedanum spp. (Umbelliferae).

• Archives of Pharmacal Research
• /
• v.29 no.2
• /
• pp.131-134
• /
• 2006

A new compound 2 and two known guaiane-type sesquiterpenoids were isolated from the methylene chloride-soluble fraction of the methanolic extract of the fruits of Torilis japonica (Umbelliferae) through repeated silica gel and Sephadex LH-20 column chromatography. Their chemical structures were elucidated as torilin (1), 11-acetoxy-8-angeloyloxy-$1{\beta}$-hydroxy-4-guaien-3-one ($1{\beta}$-hydroxytorilin, 2), and 11-acetoxy-8-angeloyloxy-$1{\alpha}$-hydroxy-4-guaien-3-one ($1{\alpha}$-hydroxytorilin, 3) by spectroscopic analysis. Compounds 1-3 exhibited cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells.

• Korean Journal of Pharmacognosy
• /
• v.1 no.1
• /
• pp.25-32
• /
• 1970

Decursin, decursinol and nodakenin which were isolated from the root of Angelica gigas $N_{AKAI}$ (Umbelliferae) that is used as a botanical drug Dang-Gui (當歸) in Korea show following general pharmacologic activities. Decursin and decursinol increased the motility of the excised duodenum of the rabbit, but nodakenin did not. All of these three compounds depressed the heart contraction of the frog and blood pressure of the carotid artery and respiration of the rabbit. Decursin increased uterus contraction of the rabbit, but decursinol depressed it. And the tonus of the muscle of the earth worm was increased by decursinol, but was decreased by decursin.

• Journal of Evidence-Based Herbal Medicine
• /
• v.3 no.1
• /
• pp.35-41
• /
• 2010

From the roots of Angelica dahurica Bentham et Hooker (Umbelliferae), three known coumarin derivatives have been isolated and identified as 8-(2-hydroxy-3-methoxy-3-methylbutyloxy) psoralen, 5,8-di(2,3-dihydroxy-3-methylbutyloxy) psoralen, 9-[3-($\beta$-D-glucopyranosyloxy)-2-hydroxy-3-methylbutoxy]-7H-furo[3,2-g][1]benzopyran-7-one. This is the first report of the occurrence of these compounds in this plant. These three compounds were tested for activity in septic shock model. Among these compounds, 2 showed relatively strong preventive activity against septic shock.

• Korean Journal of Pharmacognosy
• /
• v.24 no.3
• /
• pp.192-196
• /
• 1993

Essential oil of the root of Angelica decursiva(Miq.) Fr. et Sav. (Umbelliferae) was investigated. Essential oil was obtained from the dried roots by steam distillation and fractionated by column chromatography. Each isolate or fraction was identified by GC, GC-MS and spectral analysis. It was found to contain ten monoterpenes such as ${\alpha}-pinene$ (7.0%) etc. Three hydrocarbons, two aldehydes, three sesquiterpenes, two sesquiterpene alcohols, one aromatic compounds, one ketone, isobonyl acetate and two lactones were tentatively identified.

• Natural Product Sciences
• /
• v.25 no.3
• /
• pp.181-199
• /
• 2019

Angelica decursiva Fr. et Sav. (Umbelliferae) has traditionally been used to treat different diseases due to its antitussive, analgesic, and antipyretic activities. It is also a remedy for thick phlegm, asthma, and upper respiratory infections. Recently, the leaf of A. decursiva has been consumed as salad without showing any toxicity. This plant is a rich in different types of coumarin derivatives, including dihydroxanthyletin, psoralen, dihydropsoralen, hydroxycoumarin, and dihydropyran. Its crude extracts and pure constituents possess anti-inflammatory, anti-diabetic, anti-Alzheimer disease, anti-hypertension, anti-cancer, antioxidant, anthelmintic, preventing cerebral stroke, and neuroprotective activities. This valuable herb needs to be further studied and developed not only to treat these human diseases, but also to improve human health. This review provides an overview of current knowledge of A. decursiva metabolites and their biological activities to prioritize future studies.

• YAKHAK HOEJI
• /
• v.19 no.1
• /
• pp.16-20
• /
• 1975

A polyacetylenic compound ws isolated from the subterranean parts of Bupleurum falcatum L. (Umbelliferae) and its structure was elucidated as pentadecadiene-(2, 9)-diyn-(4, 6)-ol(1) acetate.

• Proceedings of the Zoological Society Korea Conference
• /
• 1995.10b
• /
• pp.142.1-142
• /
• 1995

No Abstract, See Full Text

• Korean Journal of Plant Taxonomy
• /
• v.42 no.2
• /
• pp.171-177
• /
• 2012

Two naturalized species, Chaerophyllum tainturieri Hook. (Umbelliferae) and Barbarea verna (Mill.) Asch. (Cruciferae) were newly reported from South Korea. C. tainturieri., 'Jeon-Ho-A-Jae-Bi', was found at World Cup park in Sangam-dong, Mapo-gu, in Seoul, and the genus Chaerophyllum is reported for the first time from South Korea in the present paper. It is distinguished from the genus Sphallerocarpus by having cylindrical fruit, and each furrow with one vitta. B. verna, 'Bom-Na-Do-Naeng-I', was found on a riverside area of Suyeong River, Geumsa-dong, in Busan. It can be distinguished from B. orthoceras by silique 4-8 mm long , seeds 1-2 mm long, and basal rosette leaves with a 4-11 large pairs of lateral lobes.