• 대한방사선기술학회지:방사선기술과학
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• 제47권2호
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• pp.97-105
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• 2024

The examination needle used in ultrasound biopsy is a medical device used to determine whether there is an abnormality in the tissue. Typically, stainless steel is the standard material used for such needles; however, this study wanted to identify a material that could better enhance sound compared to traditional stainless steel. In this study, six types of needle materials available with the biopsy gun were inserted into pork and ultrasound images according to the curved probe and linear probe were evaluated using ultrasound equipment. The findings revealed significant improvements in ultrasound acoustic enhancement with alternative materials compared to stainless steel (p<0.05). The results regarding the depth of each ultrasound image using the curved probe showed that tungsten and brass had high sound enhancement(p<0.05), while with the linear probe, sound enhancement was high in brass, pla, aluminum, and copper(p<0.05). Due to these results, the previously used stainless needle showed lower ultrasound acoustic enhancement than the five types of materials being compared. Consequently, the outcomes of this study provide valuable insights for the development of new needle technologies aimed at minimizing patient risks and improving diagnostic accuracy.

• 한국방사선학회논문지
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• 제10권3호
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• pp.201-206
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• 2016

유방암에 관한 사회적인 관심이 증가되고 있는 가운데 진단의 가장 기본이 되는 검사는 유방 X선 촬영과 유방 초음파 검사이다. 특히 유방 미세석회화는 조직학적 진단을 필요로 하며 유방 미세석회화 조직검사를 시행하고 있다. 이에 미세석회화 진단에 기본이 되는 X선 유도 하 조직검사(needle localized open biopsy)와 초음파 유도 하 조직검사(sono guided core needle biopsy)를 분석하여 평가하고자 한다. 유방 미세석회화를 주소로 내원한 환자에서 확대 촬영을 시행한 241예를 대상으로 X선 유도 하 조직검사(needle localized open biopsy)와 초음파 유도 하 조직검사(sono guided core needle biopsy)의 연령대 별 분포와 병소의 위치를 분석하고 확대촬영 시행 후 이루어진 검사를 분류해서 X선 유도 하 조직검사와 초음파 유도 하 조직검사의 빈도를 분석하고 악성과 양성의 결과를 확인 하였다. 그 결과 X선 유도 하 조직검사(needle localized open biopsy)가 64예(26.6%)로 초음파 유도 하 조직검사(sono guided core needle biopsy) 12예(4.9%)에 비해 5.4배 높은 것으로 나타났다. 초음파 장비의 발달과 입체정위 흡입법(stereotactic vacuum-assisted biopsy)등의 발달로 미세석회화의 조직학적 진단방법이 다양해지고 있지만, 각각 검사의 특성과 한계점을 고려해 볼 때 X선 유도 하 조직검사(needle localized open biopsy)가 유방 미세석회화 병변에서는 정확한 조직학적 진단을 제공한다고 사료된다.

• 대한방사선기술학회지:방사선기술과학
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• 제38권3호
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• pp.213-220
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• 2015

본 연구는 3차원 입체정위 유방생검술의 정확도를 알아보고, 심부침생검을 이용하여 Stereotactic biopsy과 Sonoguided biopsy의 정확도와 정밀도를 평가하고자 한다. Stereotactic QC phantom을 이용하여 실제 5개의 target 위치로 3D sterotactic machine의 정확도를 측정하고, CT장비로 Scan하여 실측을 구해 X, Y, Z의 길이의 정밀도를 비교한다. 유방조직과 유사하게 제작한 Agar power phantom을 이용하여 5개의 각기 다른 needle tip Target을 통해 3D sterotactic machine과 2D ultrasound machine의 정확도를 비교하고, Z축을 장비별로 실측하여 정밀도와 신뢰도를 비교하며, 6개의 모조병소 Target을 심어놓은 Medical application phantom으로 표적하여 육안검사와 Specimen검사를 통해 정확도를 확인하였다. Stereotactic QC phantom으로 측정한 3D sterotactic machine의 정확도는 100%였으며, CT와 비교한 정밀도는 X, Y, Z축이 모두 p>0.05로 나타났다. Agar powder phantom으로 측정한 두 장비의 정확도는 100%의 정확도를 보였으며, CT와 두 장비 사이에는 p > 0.05로 차이가 없었다. 그러나 2명의 방사선사가 측정한 신뢰도분석에서 3D sterotactic machine은 ICC가 0.954였고, 2D ultrasound machine은 0.785로 2D ultrasound machine이 술자에 따라 차이가 있었다. Medical application phantom의 실험에서 3D sterotactic machine은 Sliced boneless ham을, 2D ultrasound machine은 small chalk powder group를 찾을 수 없었다. Phantom을 이용한 3차원 입체정위 유방생검술의 정확성은 우수하게 나타났고, 인체조직과 비슷한 Agar powder phantom과 유방 조직과 비슷한 Medical application phantom을 이용하여 Stereotactic biopsy과 Sonoguided biopsy의 정확도와 정밀도 모두 우수하게 나타났다. 또한 Medical application phantom의 심부침생검의 정확성 평가에서 각 검사에 따라 생검 표본이 병소의 형태에 따라 상이하게 채취되었고, 3차원 입체정위 유방생검술의 재현성이 유방 초음파검사보다 술자의 영향없이 우수하였다.

• Archives of Plastic Surgery
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• 제35권1호
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• pp.62-66
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• 2008

Purpose: Axillary osmidrosis is a distressing disorder characterized by unpleasant odor from axillary area and it is mainly associated with apocrine glands but also associated with eccrine glands. For surgical treatment of osmidrosis, recently ultrasound assisted liposuction(UAL) had been performed for many patients. According to the recent studies about ultrasound assisted liposuction for the treatment of osmidrosis, histologic studies about apocrine gland had been applied for 35 cases, but there were rare mention about eccrine gland and the relationship between two glands. The purpose of this article is to evaluate the effect of ultrasound assisted liposuction for the treatment of axillary osmidrosis on apocrine and eccrine glands. Methods: From January 2004 to January 2007, 35 patients underwent ultrasound assisted liposuction for the treatment of osmidrosis and 5 patients underwent histologic studies. Histologic examinations were performed before and after ultrasound assisted liposuction and each biopsy was performed in central axillary area. The volume ratio of both glands, presence of degeneration were examined. And in aspirates, distribution and density of both glands and their morphological changes were examined. Results: Preoperative biopsy results showed average volume ratio of apocrine glands to eccrine glands was 65 : 35. According to the postoperative biopsy results, the volume of apocrine glands in dermis were significantly reduced and glands were degenerated, but the volume of eccrine glands were slightly reduced and glands were mildly damaged. And the average volume ratio of two glands was 20 : 80. According to biopsy results of aspirates, the volume ratio of two glands was 85 : 15 and apocrine glands had significantly greater proportion. Conclusion: By comparison of each biopsy result, apocrine glands were more significantly reduced and degenerated than eccrine glands in all 5 cases. However, further studies with large sample sizes and close examinations are required.

• Asian Pacific Journal of Cancer Prevention
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• 제17권10호
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• pp.4689-4692
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• 2016

Purpose: To study the clinical application value of ultrasound guided thyroid fine needle aspiration biopsy and thinprep cytology testing in diagnosis of thyroid disease. Methods: A total of 78 patients with thyroid nodules were enrolled, 34 males and 44 females, aged 33-64 years old with mean age of 47.6 years. All underwent thyroid module fine needle puncture after surgery to assess cell pathology and histopathological features. Results: Sufficient specimens were obtained from all of 78 patients, the cytological results of 73 cases (93.6 %) being consistent with pathological results. While 20 cases (25.6 %) were malignant tumors, 44 (56.4 %) were benign and 9 (11.5 %) were non-tumor lesions. The sensitivity of benign and malignant thyroid nodule by thyroid fine needle puncture was 90.9 %, specificity was 98.1 % and the positive predictive value was 96.3 %. Conclusions: It is demonstrated that ultrasound-guided thyroid fine needle aspiration biopsy and thinprep cytology testing have diagnostic value in clinical application for thyroid disease,showing good diagnostic coincidence rates with histopathological examination. They can thus be regarded as safe and effective for preoperative diagnosis and providing an appropriate basis for selection of surgery.

• 대한영상의학회지
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• 제84권6호
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• pp.1233-1243
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• 2023

경피적 초음파 유도생검은 진단 및 치료 계획을 정하기 위해 다양한 신체 병변에 대한 병리 확인에 유용한 시술이다. 하지만 깊은 골반 병변은 병리진단이 어려운데 장, 방광, 주요 혈관, 그리고 골반뼈로 인해 경피적 접근이 어렵고 위험하기 때문이다. 여성의 경우 질은 탄력적이고 골반의 내부 장기와 가깝다. 따라서 경질 초음파는 골반 병변에 대한 병리진단을 위해 효과적이고 안전한 길잡이 역할을 할 수 있다. 이 종설의 목적은 경질 초음파 유도생검의 적응증과 방법을 소개하고, 또한 보고된 진단 정확도 및 안정성을 기술하고자 한다.

• 대한기관식도과학회지
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• 제6권2호
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• pp.164-171
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• 2000

Background and Objectives： Necrotizing lymphadenitis or Kikuchi's disease is characterized by cervical lymphadenopathy of unknown etiology with unique histologic findings in young female patients. The importance of this disease lies in the fact that it can be easily misdiagnosed as malignant lymphoma, hence, clinicians need to aware of this disease entity. The purpose of this study is to report the clinicopathologic findings, radiographic findings, and many laboratory tests in order to contribute to the diagnosis and treatment of necrotizing lymphadenitis. Materials and Methods： We evaluated 31 patients, who were diagnosed as necrotizing lymphadenitis by excisional biopsy or fine needle aspiration cytology or ultrasound guided 18G cutting needle biopsy, retrospectively. Result : The median age was 24.8 years (range 12 to 43 years) and the male to female ratio was 1 : 2.4(9：22), with 14 females (45.1%) under 30 years. The common chief complaints were neck mass, easy fatigue and fever. Lymph node enlargement was limited to the cervical area in most cases (28cases : 90.3%). The involved lymph nodes were usually multiple (20cases : 64.5%), unilateral (26cases 83.9%) and small sized. Leukopenia (19cases : 61.3%) and elevation of ESR (18cases : 58.1%) appeared most frequently in the abnormal laboratory data. These symptoms will be gone spontaneoulsy without any specific treatment in several weeks or months. Conclusion : We should consider open biopsy or fine needle aspiration cytology or ultrasound guided cutting needle biopsy with lymph node in patients who have cervical lymphadenopathy with easy fatigue and fever, especially young women to exclude other conditions such as malignant lymphoma and tuberculosis, etc.

• 한국방사선학회논문지
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• 제15권7호
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• pp.1057-1064
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• 2021

본 연구는 초음파 조직검사 시에 실내 공기 중 HCHO 농도변화를 관찰하고자 실제 조직검사와 동일한 환경조건을 모사하여 진행하였다. 초음파 검사실의 밀폐, 환기, 포르말린 용기 개봉, 포르말린 용기 밀봉, 재환기의 다섯 단계를 연속적으로 진행하며 실내의 HCHO 농도변화를 측정하였다. 측정한 HCHO 농도변화는 그래프를 이용하여 시각화하였다. 3회에 걸쳐 측정된 농도 변화값의 일치도를 급내상관계수를 이용하여 분석한 결과, 상관계수 값이 0.989로 통계적으로 유의한 결과를 나타내었다(p<0.05). 연구 결과를 토대로 영상의학적 검사 분야에서 HCHO의 노출 환경 내에 근무하고 있는 의료종사자들 스스로 업무 중 노출 관리 필요성에 대한 인식개선과 더불어 노출 관리를 위한 환경구축 및 대책 마련에 대하여 적극적인 논의가 이루어지길 바란다.

• 한국임상수의학회지
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• 제21권2호
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• pp.181-183
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• 2004

Hepatic mass was aspirated under the guidance with ultrasound in 9-year old female maltese with signs of anorexia, hematochezia, vomiting, depression, and abdominal distension. Radiographic and abdominal ultrasonographic examinations were performed, which revealed enlarged tubular shaped uterine mass and solitary, small round hyperechoic hepatic mass dorsal to gall bladder as an incidental finding. Ultrasound-guided fine needle aspiration was completed, but histologic confirmation should be made for definitive diagnosis by tissue core or wedge biopsy.

• 동의생리병리학회지
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• 제26권6호
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• pp.980-982
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• 2012

Metastasis to the pancreas from extra-pancreatic primary cancers are rare; they commonly present as a manifestation of widespread disease and rarely as an isolated mass of the pancreas. Examinations showed a pancreatic tumor infiltrating the pancreas tail portion and an endoscopic ultrasound guided percutaneous biopsy proved that the lesion was metastatic from the lung carcinoma. Most metastatic cases of the pancreas tend to be discovered in patients with widely disseminated malignant disease. In addition, patients with pancreatic metastasis are often asymptomatic, the metastatic lesions are found incidentally, and are misdiagnosed as primary pancreatic tumors. This report that patient undergoing chemotherapy for a small cell lung cancer, who 1 year and 3 months later, accidentally diagnosed of solitary pancreas metastasis and confirmed histology by needle biopsy using endoscopic ultrasound.