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Evaluation of the Accuracy and Precision Three-Dimensional Stereotactic Breast Biopsy

3차원 입체정위 유방생검술의 정확도 및 정밀도 평가

  • Lee, Mi-Hwa (Dept. of Health Care, Hanseo University, Dept. of Radiology, Kyung Hee University Hospital at GANGDONG)
  • 이미화 (한서대학교 보건의료학과.강동경희대학교병원 영상의학과)
  • Received : 2015.07.29
  • Accepted : 2015.09.07
  • Published : 2015.09.30

Abstract

This research was study the accuracy of three-dimensional stereotactic breast biopsy, using a core Needle Biopsy and to assess the accuracy of Stereotactic biopsy and Sono guided biopsy. Using Stereotactic QC phantom to measure the accuracy of the 3D sterotactic machine. CT Scan and equipment obtained in the measured X, Y, Z and compares the accuracy of the length. Using Agar power phantom compare the accuracy of the 3D sterotactic machine and 2D ultrasound machine. Z axis measured by the equipment to compare the accuracy and reliability. Check the accuracy by using visual inspection and Specimen Medical application phantom. The accuracy of the 3D sterotactic machine measured by Stereotactic QC phantom was 100%. Accuracy as compared to CT, all of X, Y, Z axis is p > 0.05. The accuracy of the two devices was 100% as measured by Agar powder phantom. There was no difference between t he t wo d evices as C T and p > 0.05. 3D sterotactic machine of the ICC was 0.954, 2D ultrasound machine was 0.785. 2D ultrasound machine was different according to the inspector. Medical application phantom experiments in 3D sterotactic machine could not find the Sliced boneless ham. 2D ultrasound machine has not been able to find a small chalk powder group. The reproducibility of the three-dimensional stereotactic breast biopsy was better than effect of Sono guided biopsy.

본 연구는 3차원 입체정위 유방생검술의 정확도를 알아보고, 심부침생검을 이용하여 Stereotactic biopsy과 Sonoguided biopsy의 정확도와 정밀도를 평가하고자 한다. Stereotactic QC phantom을 이용하여 실제 5개의 target 위치로 3D sterotactic machine의 정확도를 측정하고, CT장비로 Scan하여 실측을 구해 X, Y, Z의 길이의 정밀도를 비교한다. 유방조직과 유사하게 제작한 Agar power phantom을 이용하여 5개의 각기 다른 needle tip Target을 통해 3D sterotactic machine과 2D ultrasound machine의 정확도를 비교하고, Z축을 장비별로 실측하여 정밀도와 신뢰도를 비교하며, 6개의 모조병소 Target을 심어놓은 Medical application phantom으로 표적하여 육안검사와 Specimen검사를 통해 정확도를 확인하였다. Stereotactic QC phantom으로 측정한 3D sterotactic machine의 정확도는 100%였으며, CT와 비교한 정밀도는 X, Y, Z축이 모두 p>0.05로 나타났다. Agar powder phantom으로 측정한 두 장비의 정확도는 100%의 정확도를 보였으며, CT와 두 장비 사이에는 p > 0.05로 차이가 없었다. 그러나 2명의 방사선사가 측정한 신뢰도분석에서 3D sterotactic machine은 ICC가 0.954였고, 2D ultrasound machine은 0.785로 2D ultrasound machine이 술자에 따라 차이가 있었다. Medical application phantom의 실험에서 3D sterotactic machine은 Sliced boneless ham을, 2D ultrasound machine은 small chalk powder group를 찾을 수 없었다. Phantom을 이용한 3차원 입체정위 유방생검술의 정확성은 우수하게 나타났고, 인체조직과 비슷한 Agar powder phantom과 유방 조직과 비슷한 Medical application phantom을 이용하여 Stereotactic biopsy과 Sonoguided biopsy의 정확도와 정밀도 모두 우수하게 나타났다. 또한 Medical application phantom의 심부침생검의 정확성 평가에서 각 검사에 따라 생검 표본이 병소의 형태에 따라 상이하게 채취되었고, 3차원 입체정위 유방생검술의 재현성이 유방 초음파검사보다 술자의 영향없이 우수하였다.

Keywords

References

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