• Korean Journal of Medicinal Crop Science
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• v.11 no.2
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• pp.102-108
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• 2003

This experiment was conducted to evaluate the diversity and purity of the Korean ginseng (Panax gjnseng) lines developed by the pure line selection using RAPD markers. Four primer (OPA 19, OPM 11, URP 3 and UBC 98) out of the 48 primer tested produced band which showed within-line polymorphisms at least in one line. Within-line polymorphisms were detected in six lines by OPA 19, in four lines by URP 03, in five lines by OPM 11, and in one line by UBC 98 respectively. Five plants obtained from the commercial cultivar 'Cheonpung' were differentiated using the primers OPA 19 and OPM 11. Five plants obtained from the 'Yeonpung were differentiated using the primer OPM 11. Detection of within-line RAPD polymorphisms might be attributed to the fact that cross pollination appear in P. gjnseng and a long period of three to four years required to reach the reproductive stage thereby delay the process to homozygosity.

• Journal of Ginseng Research
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• v.35 no.1
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• pp.52-59
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• 2011

Recently, new ginseng cultivars having superior agricultural traits have been developed in Korea. For newly developed plant cultivars, the identification of distinctiveness is very important factors not only in plant cultivar management but also in breeding programs. Thus, eighty-five inter simple sequence repeat (ISSR) primers were applied to detect polymorphisms among six major Korean ginseng cultivars and two foreign ginsengs. A total of 197 polymorphic bands with an average 5.8 polymorphic bands and 2.9 banding patterns per assay unit across six Korean ginseng cultivars and foreign ginsengs from 236 amplified ISSR loci with an average 6.9 loci per assay unit were generated by 34 out of 85 ISSR primers. Three species of Panax ginseng including the Korean ginseng cultivars, P. quinquefolius, and P. notoginseng, could be readily discriminated using most tested primers. UBC-821, UBC-868, and UBC-878 generated polymorphic bands among the six Korean ginseng cultivars, and could distinguish them from foreign ginsengs. Sequence characterized amplified region (SCAR) marker system was introduced in order to increase the reproducibility of the polymorphism. One SCAR marker, PgI821C650, was successfully converted from the randomly amplified polymorphism by UBC-821. It showed the expected dominant polymorphism among ginseng samples. In addition, the specific polymorphism for Sunwon was generated by treating Taq I restriction enzyme to polymerase chain reaction products of PgI821C650. These results will serve as useful DNA markers for identification of Korean ginseng, especially Sunwon cultivar, seed management, and molecular breeding program supplemented with marker-assisted selection.

• Computational Structural Engineering
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• v.5 no.1
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• pp.91-96
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• 1992

Earthquake resistant design is evolutionary, and, although great progress has been made since seismic design was made mandatory by building codes, it is still not completely understood. In this paper, a 10 story steel building is analyzed and its results are compared by applying two different actual ground motions to the structure. 12 sets of Loma Prieta, California, earthquake data which occurred in 1989, and recorded 7.1 on the Richter scale and 9 sets of Valparaiso, Chile, earthquake data which occurred in 1985, and recorded 7.8 on the Richter scale were scaled to zone 2B level of UBC-88. By applying earthquake ground motions which had similar Richter scale magnitude, it was found that the Chile earthquake which had long duration of ground motion affected about twice bigger than that of California earthquake which had relatively short duration of ground motion. In addition to the peak ground motion, the duration of the ground motion is a very important factor in structural design.

• Journal of the Earthquake Engineering Society of Korea
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• v.8 no.4
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• pp.11-20
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• 2004

This paper suggests the site-dependent ductility factor which is a key component of response modification factor(R). To compute the ductility factor, a group of 1,860 ground motions recorded from 47 earthquake was considered. Based on the local site conditions at the recording station, ground motions were classified into four groups according to average shear wave velocity. This site classification was consistent with site categories of the UBC(1997), NEHRP(1997) and IBC 2000(1997). Based on the results of regression analysis, a simplified equations were proposed to compute site-dependent ductility factors. The proposed equations were relatively simple and provide a good estimation of mean ductility factors. Based on the proposed equation, ductility factors considering the site conditions can be evaluated in accordance with the present building codes.

• BMB Reports
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• v.48 no.1
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• pp.25-29
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• 2015

Ubiquitination is a post translational modification which mostly links with proteasome dependent protein degradation. This process has been known to play pivotal roles in the number of biological events including apoptosis, cell signaling, transcription and translation. Although the process of ubiquitination has been studied extensively, the mechanism of polyubiquitination by multi protein E3 ubiquitin ligase, SCF complex remains elusive. In the present study, we identified UbcH5a as a novel stimulating factor for poly-ubiquitination catalyzed by $SCF^{hFBH1}$ using biochemical fractionations and MALDI-TOF. Moreover, we showed that recombinant UbcH5a and Cdc34 synergistically stimulate $SCF^{hFBH1}$ catalyzed polyubiquitination in vitro. These data may provide an important cue to understand the mechanism how the SCF complex efficiently polyubiquitinates target substrates.

• Tuberculosis and Respiratory Diseases
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• v.80 no.1
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• pp.11-20
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• 2017

Approximately one in four patients with chronic obstructive pulmonary disease (COPD) have asthmatic features consisting of wheezing, airway hyper-responsiveness or atopy. The Global initiative for Asthma/Globalinitiative for chronic Obstructive Lung Disease committee recently labelled these patients as having asthma-COPD overlap syndrome or ACOS. ACOS also encompasses patients with asthma, ${\geq}40$ years of age, who have been cigarette smokers (more than 5-10 pack years) or have had significant biomass exposure, and demonstrate persistent airflow limitation defined as a post-bronchodilator forced expiratory volume in 1 second ($FEV_1$)/forced vital capacity of <70%. Data over the past 30 years indicate that patients with ACOS have greater burden of symptoms including dyspnea and cough and show higher risk of COPD exacerbations and hospitalizations than those with pure COPD or pure asthma. Patients with ACOS also have increased risk of rapid $FEV_1$ decline and COPD mortality. Paradoxically, experimental evidence to support therapeutic decisions in ACOS patients is lacking because traditionally, patients with ACOS have been systematically excluded from therapeutic COPD and asthma trials to maintain homogeneity of the study population. In this study, we summarize the current understanding of ACOS, focusing on definitions, epidemiology and patient prognosis.

• Journal of the Earthquake Engineering Society of Korea
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• v.17 no.1
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• pp.11-19
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• 2013

This research presents that seismic performance of steel moment resisting frame building designed by past provision(UBC, Uniform Building Code) before and after retrofitted with BRB (Buckling-Restrained Brace) was evaluated using response modification factor (R-factor). In addition, the seismic performance of the retrofitted past building was compared with that specified in current provision. The past building considered two different connections: bilinear connection, which was used by structural engineer for building design, and brittle connection observed in past earthquakes. The nonlinear pushover analysis and time history analysis were performed for the analytical models considered in this study. The R-factor was calculated based on the analytical results. When comparing the R-factor of the current provision with the calculated R-factor, the results were different due to the hysteresis characteristics of the connection types. After retrofitted with BRBs, the past buildings with the bilinear connection were satisfied with the seismic performance of the current provision. However, the past buildings with the brittle connection was significantly different with the R-factor of the current provision.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.3
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• pp.179-179
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• 2004

In the near future we can expect a change in charging the Internet service. The flat charging maybe replaced with a usage-based charging. In line with this movement, we propose a method of charging the assured-quality Internet services for the next generation network by introducing a UBC (usage-based charging) scheme over the conventional flat charging platform. First, we investigate the attribute of elastic traffic generated by assured services in IP network. Next, we propose a new method to relate the bandwidth usage with the pricing for the elastic traffic, which is based partially on the usage rate of the network bandwidth. Next, we propose a charging function for elastic traffic, which is applicable to any type of assured Internet services. Finally, we discuss the implication of the work via simple numerical experiments.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.3
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• pp.21-28
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• 2004

In the near future we can expect a change in charging the Internet service. The flat charging maybe replaced with a usage-based charging. In line with this movement, we propose a method of charging the assured-quality Internet services for the next generation network by introducing a UBC (usage-based charging) scheme over the conventional flat charging platform. First, we investigate the attribute of elastic traffic generated by assured services in IP network. Next, we propose a new method to relate the bandwidth usage with the pricing for the elastic traffic, which is based partially on the usage rate of the network bandwidth. Next, we propose a charging function for elastic traffic, which is applicable to any type of assured Internet services. Finally, we discuss the implication of the work via simple numerical experiments.

• Resources Recycling
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• v.9 no.2
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• pp.3-10
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• 2000

Used aluminum beverage can(UBC) is an important secondary resource. Domestic recycling rate of UBC should be increased from the standpoint of resource savings and environmental protection. Aluminum can to can recycling is divided into two steps. The first step was composed of the processes such as collection of used beverage cans, shredding, magnetic separation, de-lacquring, melting and casting. The second is remelting and casting, heat treatment, hot and cold rolling, annealing, and can making. With brief discussion about this recycling technology, this article covers aluminum can consumption, the present state of aluminum can recycling in Korea, Japan, USA, and Europe.