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Marginal and internal discrepancy of 3-unit fixed dental prostheses fabricated by subtractive and additive manufacturing (절삭 및 적층 가공법으로 제작된 3본 고정성 국소의치의 변연 및 내면 적합도에 관한 연구)

  • Choi, Jae-Won
    • The Journal of Korean Academy of Prosthodontics
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    • v.58 no.1
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    • pp.7-13
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    • 2020
  • Purpose: This study was to evaluate marginal and internal discrepancy of 3-unit fixed dental prostheses (FDP) fabricated by subtractive manufacturing and additive manufacturing. Materials and methods: 3-unit bridge abutments without the maxillary left second premolar were prepared (reference model) and the reference model scan data was obtained using an intraoral scanner. 3-unit fixed dental prostheses were fabricated in the following three ways: Milled 3-unit FDP (MIL), digital light processing (DLP) 3D printed 3-unit FDP (D3P), stereolithography apparatus (SLA) 3D printed 3-unit FDP (S3P). To evaluate the marginal/internal discrepancy and precision of the prosthesis, scan data were superimposed by the triple-scan protocol and the combinations calculator, respectively. Quantitative and qualitative analysis was performed using root mean square (RMS) value and color difference map in 3D analysis program (Geomagic control X). Statistical analysis was performed using the Kruskal-Wallis test (α=.05), MannWhitney U test and Bonferroni correction (α=.05/3=.017). Results: The marginal discrepancy of S3P group was superior to MIL and D3P groups, and MIL and D3P groups were similar. The D3P and S3P groups showed better internal discrepancy than the MIL group, and there was no significant difference between the D3P and S3P groups. The precision was excellent in the order of MIL, S3P, and D3P groups. Conclusion: Within the limitation of this study, the 3-unit fixed dental prostheses fabricated by additive manufacturing showed better marginal and internal discrepancy than the those of fabricated by subtractive manufacturing, but the precision was poor.

Anti-Müllerian hormone levels as a predictor of clinical pregnancy in in vitro fertilization/intracytoplasmic sperm injection-embryo transfer cycles in patients over 40 years of age

  • Park, Hyun Jong;Lyu, Sang Woo;Seok, Hyun Ha;Yoon, Tae Ki;Lee, Woo Sik
    • Clinical and Experimental Reproductive Medicine
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    • v.42 no.4
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    • pp.143-148
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    • 2015
  • Objective: The aim of the current study was to determine the predictive value of anti-$M{\ddot{u}}llerian$ hormone (AMH) levels for pregnancy outcomes in patients over 40 years of age who underwent in vitro fertilization or intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) cycles. Methods: We retrospectively analyzed the medical records of 188 women aged 40 to 44 years who underwent IVF/ICSI-fresh ET cycles due to unexplained infertility in the fertility center of CHA Gangnam Medical Center. Patients were divided into group A, with AMH levels <1.0 ng/mL (n=97), and group B, with AMH levels ${\geq}1.0ng/mL$ (n=91). We compared the clinical pregnancy rate (CPR) in the two groups and performed logistic regression analysis to identify factors that had a significant effect on the CPR. Results: The CPR was significantly lower in group A than group B (7.2% vs. 24.2%, p<0.001). In multivariate logistic regression analysis, AMH levels were the only factor that had a significant impact on the CPR (odds ratio, 1.510; 95% confidence interval, 1.172-1.947). The area under the receiver operating characteristic curve for AMH levels as a predictor of the CPR was 0.721. When the cut-off level of AMH was set at 1.90 ng/ mL, the CPR was 6.731-fold higher in the group with AMH levels ${\geq}1.90ng/mL$ than in the group with AMH levels <1.90 ng/mL (p<0.001). Conclusion: Our study showed that AMH levels were predictive of clinical pregnancy in infertility patients over 40 years of age. Further prospective studies should be conducted to validate the predictive capability of AMH levels for the outcome of clinical pregnancy.

Isolation of Cymbidium mild mosaic virus (Cymbidium mild mosaic virus의 분리동정)

  • Chang M. U.;Doi Y.;Yora K.
    • Korean journal of applied entomology
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    • v.17 no.3 s.36
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    • pp.131-138
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    • 1978
  • A virus named Cymbidium mild mosaic virus(Cy MMV), was mechanically transmitted to Chenopodium amaranticolor from the leaves of Cymbidium with mild mosaic symptoms. The virus was cultured in C. amaranticolor, in which it produced local chlorotic and ring spots, followed by systemic vein clearing with distortion. CyMMV infected 7 out of 35 species of plants. In C. amaranticolor juice infectivity was lost by heating at $90^{\circ}C$ for 10 miuntes, and by aging at$20^{\circ}C$ for 60 days, and by diluting at $10^{-6}$ when bioassayed on C. amaranticolor. CyMMV was not transmitted by Myzus persicae. The virus was purified after clarification of homogenized C. amaranticolor leaf tissues with chloroform, by differential centrifugation followed by sucrose density gradient centrifugation. Electron microscopic examination of purified preparation showed spherical particles of 28nm in diameter. The UV absorption spectrum of purified preparation was typical of u nucleoprotein (max. at 261nm. min. at 243nm), and showed 260/280=1.72 and max/min=1.26. The value of the sedimentation coefficient of the virus was S20.w=126. In gel-diffusion tests, CyMMV antiserum reacted with CarMV, but not with any of four other viruses (BBWV, CRSV, CMV, TBRV) having similar particles and properties in vitro. In ultra-thin sections of CyMMV infected tissues, a large number of virus particles were found in the cytoplasm of mesophyll cells and in xylem vessels.

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A systematic study of Glechoma L. (Lamiaceae) based on micromorphological characters and nuclear ribosomal ITS sequences (미세구조학적 형질 및 핵 리보솜 DNA의 ITS 염기서열에 의한 긴병꽃풀속(꿀풀과)의 계통분류학적 연구)

  • Jang, Tae-Soo;Lee, Joongku;Hong, Suk-Pyo
    • Korean Journal of Plant Taxonomy
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    • v.44 no.1
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    • pp.22-32
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    • 2014
  • The petal and sepal micromorphology of five species of Glechoma (Lamiaceae) was investigated to evaluate their taxonomic significance, and a molecular phylogeny using the sequences of internal transcribed spacers (ITS) regions of nuclear ribosomal DNA was carried out to resolve their phylogenetic relationships. Stomatal complexes were mostly found in the inner and outer part of the sepal from all investigated taxa, and the size length of the guard cell was variable among the taxa. Five types of trichomes (uni-cellular non-glandular trichome, multi-cellular non-glandular trichome, short-stalked capitate glandular trichome, long-stalked capitate glandular trichome, and peltate glandular trichome) were variable among the taxa as well as their distribution and density. In molecular phylogenetic studies, the genus Glechoma was composed of three geographically distinct major monophyletic groups (Europe-U.S.A., China-Korea, Japan). G. longituba in Korea and China formed well-supported monophyletic group. G. hederacea in Europe and U.S.A. formed a monophyletic and well-supported clade with G. sardoa, which are endemic species in Italy, with G. hirsuta falling as a sister to this clade. However, G. grandis did not form any phylogenetic relationships with the remaining taxa. The ITS analyses provided taxonomic boundaries of taxa in Glechoma although the petal and sepal micromorphological characters provided weak evidences of the systematic value. As further studies, incorporating more DNA regions to the matrix including other additional morphological analysis will be significant to provide clearer taxonomic structure in Glechoma.

농식품안전 정책방향

  • Jo, Jang-Yong
    • 한국환경농학회:학술대회논문집
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    • 2009.07a
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    • pp.3-18
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    • 2009
  • It is difficult for consumers to satisfy high safety request with post-management method such as inspection and surveillance, as various changes in-and-out of the country associated with food safety. In terms of food safety problems related to foods, it is crucial to recognize public health and consumer protection and construct pre-preventive Food Control System. A joint committee, FAO/WHO made the following consultations to the National Food Safety System. ${\circ}$ Approach entirely from farm to table ${\circ}$ Get ready for Risk Analysis System ${\circ}$ Secure transparency ${\circ}$ Establish the optimal policy by evaluating the effect of regulation When it comes to summarizing the consultation, it would be accumulated as two key words; "Efficiency" and "Credibility". Whereas the problem of efficiency focuses on precaution rather than post-management, it requires policy option to maximize consumer's benefit by evaluating the cost for the Food Safety Management and its benefit. Also, analyzing risk's character and amount, demanding an optimal means, and introducing scientific analysis system put much value on the stakeholder's communications are procedure's security which can satisfy both "Efficiency" and "Credibility" simultaneously. Especially, it is emphasized here that Risk Assessment need to be separated from Risk Management. This action is a valid means of credibility security throughout improving transparency. A number of nations and organizations have reformed the method of food management passing through reflection and examination of the prior National Food Safety Management since BSE occurred in Britain, 1996. FSA; Food Standard Agency, AFFSA, EFSA, BfR, and FSC are Risk Assessment Organization functionally separated from Risk Management Organization, JECFA, JMCFA, JMPR, JEMRA in Codex charge Risk Assessment internationally. In case of advanced countries excluding several those such as The U.S. and so forth, though these Risk Assessment Organizations are either separated functionally within Risk Management Organization or operated as apart organ, common factors are in which it has independence as Science Base. While securing independence of Risk Assessment Function, it is a tendency Risk Management should be functionally unified into efficiency as well. Though Germany constructs integral Risk Management System of diverse ways according to social and political conditions of each country such as GFOCP, DVFA, SNFA, CFIS and AQIS, there is a key word in the center, "Securing efficiency of Food Safety Management". However our nation has a representative plural;diversified system with The U.S., we took a step forward for unification as empowering policy's generalization;adjustment and Risk Assessment Function by means of enacting the "Food Safety Fundamental Law" in 2008 and establishing the "Food Safety Policy Commission" with private and governmental sectors in the Prime Minister's office. Even though the unification of Risk Management hereby increased, there is the lack of strengthening function of Risk Assessment and securing independence. It needs to be required for the professional committee in Food Safety Policy Commission to develop as a exclusive office of Risk Assessment by separating from a policy decision. Administrative Branches should reinforce feeble functions such as fundamental investigation;research for carrying out Risk Assessment with securing efficiency throughout reassessment of prior Risk Management Means.

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Effects of Weed Control on Pseudocercospora vitis and Fruit Characteristics in Campbell Early Vineyard (캠벨얼리 포도원에서 잡초관리 방법이 갈색무늬병 및 과실특성에 미치는 영향)

  • Kim, Sun-Kook;Choi, Won-Ho;Lee, Seok-Ho;Lee, Yun-Sang;Yoon, Changmann;Hong, Seong-Tac
    • Korean Journal of Organic Agriculture
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    • v.23 no.4
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    • pp.897-909
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    • 2015
  • This study was conducted to evaluate the effect of weed control on disease incidence, plant growth and fruit quality, and to provide effective method to farmers at the vineyard. At the raincoat greenhouse cultivating 'Campbell Early', several weed controlling methods were compared to the control. Mean temperature of plots between soil covering (C.B., W.F., S.N., P.F. and R.H.) and non soil covering (M.W.2, M.W.3 and U.T.) were similar with $26.2^{\circ}C$ (July) and $25.8^{\circ}C$ (Aug.), but humidity of soil covering was sharply decreased in late-July under 40%. Soil water were all higher in soil covering plots than that of non-soil covering, however, soil temperature was recorded lower in soil covering plots. Disease incidence of Peudocercospora vitis according to soil coverings had effect on black plastic film mulching by decreasing grapevine leaf spot to 85% in July, 69% in August, compared to the control, with showing the smallest lesion incidence in FMB. Among growth characters, internode length and internode width of black plastic film mulching was higher than that of the control. SPAD value of black plastic film mulching was recorded the highest. It was not significant among the treatments, but brix was recorded highly in black plastic film mulching with $14{\sim}15^{\circ}Brix$.

Effects of Plant Oils and Minerals for the Inhibition of Lipase Activity of Staphylococcus aureus Isolated from Fermented Pork Meat

  • Cho, Sang-Buem;Chang, Woo-Kyung;Kim, Yun-Jung;Moon, Hyung-In;Joo, Jong-Won;Choi, In-Soo;Seo, Kun-Ho;Kim, Soo-Ki
    • Food Science of Animal Resources
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    • v.30 no.5
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    • pp.764-772
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    • 2010
  • Staphylococcus aureus lipase is regarded as a virulence factor. The response of lipase activity to various factors can provide important insights concerning the prevention of S. aureus during meat fermentation. This study was conducted to evaluate the main effects of nutrients used in culture media, and their combined effects on the inhibition of lipase activity and cell growth of pathogenic S. aureus SK1593 isolated from fermented pork meat. A Plackett-Burman design was used to evaluate the main effects of variables, including olive oil, soybean oil, grapeseed oil, sesame oil, $CuSO_4$, $MgCl_2$, $KNO_3$, $CaCl_2$, and KCl. Significant negative effects on lipase activity were detected with soybean oil, grapeseed oil, $KNO_3$, and $CaCl_2$. Additionally, these nutrients were further selected as variables for the investigation of their combined effect on lipase activity, via response surface methodology. In order to confirm the regression model, a situation that only inhibits lipase activity was simulated. The predicted lipase activity and cell growth of the simulated situation were 14.0 U/mL and $9.6\;{\log}_{10}$ (CFU/mL), respectively, and the estimated value of those in the same medium showed 15.14 U/mL and $9.4\;{\log}_{10}$(CFU/mL) respectively. The lipase activity of the simulated medium was inhibited approximately 5-fold as compared to the basal medium, but no significant differences in cell counts were noted to exist between the basal and simulated media. These results suggest that soybean oil, grapeseed oil, $KNO_3$, and $CaCl_2$ can be used to inhibit the growth of pathogenic S. aureus during the process of meat fermentation.

A Study on demand and supply of dental laboratory technician in Gangwon Province. (강원도내 치과기공소 인력수급을 위한 기초조사 연구)

  • Kwon, Soon-Seog;Hwang, Seong-Sig
    • Journal of Technologic Dentistry
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    • v.24 no.1
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    • pp.9-18
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    • 2002
  • The aim of this study is to propose effective measures for shortage of manpower of dental technology laboratory in Gangwon province by means of examining not only the history of Gangwon association, present condition of transference of members of Gangwon association from 1990, of missing members and annual rate of participation in repair education with setting object of study into Gangwon association under the influence of the Korean Dental Technology Association but also the present condition of opening and closing laboratory, amount of business connection and condition of shortage of manpower and its field with setting object of study into 28 dental technology laboratories. Results from this study are like followings : First, Gagnwon association was established in 1984 as the eleventh in the line of the board, reorganization of board is conducted 8 times up to the eighth in the line of the board in 2001. board is composed of 16 persons including president and operated its term as 3 years. Second, a number of representative and ordinary member of Gangwon association has increased gradually from 1992 to 2001. in aspect of annual rate of participation in repair education, representative's is more higher than ordinary member's overall. the worst rate of whole members' is shown as 47.9% and the its best rate is shown as 92.0%. in addition, 70$\sim$80% rate of participation into repair education is shown most frequently as 8 times of whole 20 times from 1992 to 2001. Third, 29 authorized dental technology laboratories have registered in Gangwon association until march 2002 within 9 cities and counties. in consideration of establishment location. Gangneung city has most amount as 7 laboratories(24.1%), Wonju city has 5(17.2%), Samcheok city and Sokcho city, each has 4(13.8%), Chuncheon city has 3(10.3%), Donghae city and Taeback city, each has 2(6.9%) and Yangyang and Yongwol county, each has 1(3.4%). Fourth, amount of work personnel of laboratory in Gangwon province is 1$\sim$10 persons as the maximum value. 23 laboratories(82.1%) have their own work personnel as amount of 5 and below. in aspect of main business, most of laboratories focus on the Porcelain and Crown. and 16 laboratories(57.1%) have their own expensive equipments such as Milling. its also suggests that 16 laboratories(57.1%) suffer their shortage of working personnel. specifically, 6 laboratories(21.4%) suffer the highest shortage especially in Denture field, Fifth, whole number of Gangwon association is up to 101 members (28 representatives and 73 ordinary members) until December 31th 2001. amount of immune from repair education of Gangwon association until October 2001 is up to 10 persons, and missing members from 1997 is up to 18 persons, suspension of business is up to 4 persons. in aspect of transference from 1990, transfer-in is up to 21 persons and transfer out is up to 16 persons.

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A Study on the Refarming Plan of the Low Frequency Bands according to the Transition from Analogue to Digital TV (디지털TV 전환에 따른 저대역 주파수 회수/재배치 방안 연구)

  • Yu, Hyeon-Yong
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.19 no.12
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    • pp.1470-1481
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    • 2008
  • A demand for spectrum resources, especially in the low frequency bands, is ever increasing with the development of mobile telecommunications and so is their economic value as other national resources. Also, development in mobile broadband require more bandwidth with excellent propagation characteristics, such as those frequencies in the 700/800/900 MHz bands. As a way to enhance the economic efficiency of using spectrum resources, many countries including the U.S., the U.K. and Japan, have recently focused on the refarming plan of the low frequency bands according to the transition from analogue to digital TV. By the way, as a result of WRC-07, those parts of the band $698{\sim}960\;MHz$ in Region 2 and the band $790{\sim}960\;MHz$ in Regions 1 and 3 which are allocated to the mobile service on a primary basis are identified for use by administrations wishing to implement International Mobile Telecommunications (IMT). Therefore, after analogue to digital television switchover, some administrations may decide to use all or parts of the band $698{\sim}806/862\;MHz$ for other services to which the band is allocated on a primary basis, in particular the mobile service for the implementation of IMT, while in other countries the broadcasting service will continue to operate in that band. And to conclude, bands already identified for IMT-2000 will also be able to be used for IMT. This work will help establish a policy direction for spectrum refarming in the low frequency bands in Korea(Rep. of).

Synergistic Effects of Natural Medicinal Plant Extracts on Growth Inhibition of Carcinoma (KB) Cells under Oxidative Stress (산화적 상해로 인한 상피세포암 세포(KB) 억제에 미치는 천연약용식물 추출물의 상승효과)

  • Kim, Jeong-Hee;Ju, Eun-Mi;Kim, Jin-Kyu
    • Journal of Radiation Protection and Research
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    • v.25 no.4
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    • pp.183-190
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    • 2000
  • Medicinal plants with synergistic effects on growth inhibition of canter cells under oxidative stress were screened in this study. Methanol extracts from 51 natural medicinal plants which were reported to have anticancer effort on hepatoma stomach cancer or colon cancers which are frequently found in Korean, were prepared and screened for their synergistic activity on growth inhibition of cancer cells under chemically-induced oxidative stress by using MTT assay. Twenty seven samples showed synergistic activity on the growth inhibition in various extent under chemically-induced oxidative stress. Among those samples, eleven samples such as Melia azedarach, Agastache rugosa, Catalpa ovata, Prunus persica, Sinomenium acutum Pulsatilla koreana, Oldenlandia diffusa, Anthriscus sylvestris, Schizandra chinensis, Gieditsia sinensis, Cridium officinale, showed decrease in $IC_{50}$ values more than 50%, other 16 samples showed decrease in $IC_{50}$ values between 50-25%, compared with the value acquired when medicinal plant sample was used alone. Among those 11 samples, extract of Catalpa ovata showed the highest activity. $IC_{50}$ values were decrease to 61% and 28% when carcinoma cells were treated with Catalpa ovata extract in combination of 75 and 100 uM of hydrogen peroxide, respectively.

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