• Spatial Information Research
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• v.21 no.2
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• pp.35-43
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• 2013

The aim of this research is to analyze the priority to functions of the U-city Service Aid Organization(USAO), which is to support invigorating U-City industry. This research analyzes the relative importance and the priority about the functional area and components of UASO based on AHP. This research also performs a sensitivity analysis. The research result shows that relative importance of functional area is like following orders: 1) distribution of U-City service-related information, 2) quality certification of U-City-related products and services, 3) R&D of U-City technology, 4) standardization of U-City, 5) U-City human resource development. The relative importance order of functional components is 1) establishment of U-City information distribution organization, 2) construction and management of U-City information distribution network, 3) supporting U-City information distribution and price policy, 4) providing U-City information list for distribution, 5) preparation and application of quality certification standard of U-City products and services, 6) research on legal system of U-City items, targets, and procedures for quality certification, 7) research, analysis, and provision of U-City information distribution situation, 8) level examination of constructed infrastructures and services in U-City, 9) U-City core technology development and localization of technology, 10) standardization of collected U-City information, service classification, distribution system. This research result can be applied directly to design functions of USAO. The result also can be used for duty management, human resource planning, or resource allocation.

• Journal of Korean Society for Geospatial Information Science
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• v.19 no.1
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• pp.53-61
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• 2011

The purpose of this study is to suggest development directions and elicit future research themes of U-City and future city by identifying the research trends of U-City theses. For this, meta-keywords were elicited based on the theses of U-City and future city published from mid 1990s to 2010. Centered on the meta-keywords, temporal keyword analysis was performed to compare the research trends of U-City and future city theses in Korea and oversea. The results show that most of U-City and future theses in Korea and oversea mainly dealt with technology. U-City theses in Korea have a tendency to research technology, methodology, service, planning and management in order from the early beginning. However, the U-City and future theses in oversea have a tendency to continuously study U-City applications to city through the model based on the technology and methodology. Therefore, the U-City research in Korea should focus on aspects of urban regeneration, urban scale, and so on. That is to say, the research in near future is required to apply the U-City to various urban themes.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2251-2256
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• 2015

To study effects of cellular FLICE (FADD-like IL-$1{\beta}$-converting enzyme)-inhibitory protein (c-FLIP) inhibition by RNA interference (RNAi) on sensitivity of U2OS cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis, plasmid pSUPER-c-FLIP-siRNA was constructed and then transfected into U2OS cells. A stable transfection cell clone U2OS/pSUPER-c-FLIP-siRNA was screened from the c-FLIP-siRNA transfected cells. RT-PCR and Western blotting were applied to measure the expression of c-FLIP at the levels of mRNA and protein. The results indicated that the expression of c-FLIP was significantly suppressed by the c-FLIP-siRNA in the cloned U2OS/pSUPER-c-FLIP-siRNA as compared with the control cells of U2OS/pSUPER. The cloned cell line of U2OS/pSUPER-c-FLIP-siRNA was further examined for TRAILinduced cell death and apoptosis in the presence of a pan-antagonist of inhibitor of apoptosis proteins (IAPs) AT406, with or without 4 hrs pretreatment with rocaglamide, an inhibitor of c-FLIP biosynthesis, for 24 hrs. Cell death effects and apoptosis were measured by the methods of MTT assay with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and flow cytometry, respectively. The results indicated that TRAIL-induced cell death in U2OS/pSUPER-c-FLIP-siRNA was increased compared with control cells U2OS/pSUPER in the presence or absence of AT406. Flow cytometry indicated that TRAIL-induced cell death effects proceeded through cell apoptosis pathway. However, in the presence of rocaglamide, cell death or apoptotic effects of TRAIL were similar and profound in both cell lines, suggesting that the mechanism of action for both c-FLIP-siRNA and rocaglamide was identical. We conclude that the inhibition of c-FLIP by either c-FLIP-siRNA or rocaglamide can enhance the sensitivity of U2OS to TRAIL-induced apopotosis, suggesting that inhibition of c-FLIP is a good target for anti-cancer therapy.

• Advances in environmental research
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• v.2 no.3
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• pp.167-177
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• 2013

We investigated that removal of aqueous U(VI) by nano-sized Zero Valent Iron (nZVI) and Fe(II) bearing minerals (controls) in this study. Iron particles showed different U(VI) removal efficiencies (Mackinawite: 99%, green rust: 95%, nZVI: 91%, magnetite: 87%, pyrite: 59%) due to their different PZC (Point of Zero Charge) values and surface areas. In addition, noticeable amount of surface Fe(II) (181 ${\mu}M$) was released from nZVI suspension in 6 h and it increased to 384 ${\mu}M$ in the presence of U(VI) due to ion-exchange of U(VI) with Fe(II) on nZVI surface. Analysis of Laser-Induced Breakdown Detection (LIBD) showed that breakdown probabilities in both filtrates by 20 and 200 nm sizes was almost 24% in nZVI suspension with U(VI), while 1% of the probabilities were observed in nZVI suspension without U(VI). It indicated that Fe(II) colloids in the range under 20 nm were generated during the interaction of U(VI) and nZVI. Our results suggest that Fe(II) colloids generated via ion-exchange process should be carefully concerned during long-term remediation site contaminated by U(VI) because U could be transported to remote area through the adsorption on Fe(II) colloids.

• Journal of the Korean Magnetic Resonance Society
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• v.28 no.1
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• pp.1-5
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• 2024

IscU, the iron-sulfur (Fe-S) cluster scaffold protein, is an essential protein for biogenesis of Fe-S clusters. Previous studies showed that IscU manifests a metamorphic structural feature; at least two structural states, namely the structured state (S-state) and the disordered state (D-state), interconverting in a physiological condition, was observed. Moreover, subsequent studies demonstrated that the metamorphic flexibility of IscU is important for its Fe-S cluster assembly activity as well as for an efficient interaction with various partner proteins. Although solution nuclear magnetic resonance (NMR) spectroscopy has been a useful tool to investigate this protein, the detailed molecular mechanism that sustains the structural heterogeneity of IscU is still unclear. To tackle this issue, we applied a high-pressure NMR (HP-NMR) technique to the IscU variant, IscU(I8K), which shows an increased population of the S-state. We found that the equilibrium between the S- and D-state was significantly perturbed by pressure application, and the specific regions of IscU exhibited more sensitivity to pressure than the other regions. Our results provide novel insights to appreciate the dynamic behaviors of IscU and the related versatile functionality.

• Bulletin of Food Technology
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• v.22 no.1
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• pp.29-30
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• 2009

• The Korean Society of Law and Medicine
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• v.7 no.2
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• pp.137-178
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• 2006

The purpose of this paper is to analyse the present situation and legal problems of u-health. U-health plays an important role in enlarging the healthcare service and making the healthcare service efficient. The use of Korean excellent IT technology can lead us to a world wide competitive healthcare industry. Although u-health has the weakness in privacy protection, the usefulness and convenience of u-health is great. Therefore we must analyse the legal issues of security technology, RFID, telemedicine and EMR pertaining to u-health and construct the appropriate legislative structure to resolve the legal problems of u-health.

• Journal of Information Technology Services
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• v.8 no.2
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• pp.89-115
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• 2009

A Technology Roadmap (TRM) is extensively used as a tool to manage activities of researching and developing technologies and products that can help a business achieve its goals. However, most of past studies on TRMs have limited themselves to developing in a single product or a single industry level. Few research studies have examined how TRM are used for convergence products and services for future development. The aim of this chapter is to introduce a TRM development methodology for u-City technologies and to consider its possible application at the R&D program level in Korea. This research suggests ways to develop a TRM in u-City development by segmenting u-City technologies, projecting TRM for each technology and designing TRM templates for evaluating both current and future technologies. In addition, the study further highlights to prioritize which technology is favorable for the implementation based on its economic feasibility and technological maturity.

• Smart Structures and Systems
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• v.29 no.1
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• pp.1-16
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• 2022

Despite recent breakthroughs in deep learning and computer vision fields, the pixel-wise identification of tiny objects in high-resolution images with complex disturbances remains challenging. This study proposes a modified U-net for tiny crack segmentation in real-world steel-box-girder bridges. The modified U-net adopts the common U-net framework and a novel Self-Attention-Self-Adaption (SASA) neuron as the fundamental computing element. The Self-Attention module applies softmax and gate operations to obtain the attention vector. It enables the neuron to focus on the most significant receptive fields when processing large-scale feature maps. The Self-Adaption module consists of a multiplayer perceptron subnet and achieves deeper feature extraction inside a single neuron. For data augmentation, a grid-based crack random elastic deformation (CRED) algorithm is designed to enrich the diversities and irregular shapes of distributed cracks. Grid-based uniform control nodes are first set on both input images and binary labels, random offsets are then employed on these control nodes, and bilinear interpolation is performed for the rest pixels. The proposed SASA neuron and CRED algorithm are simultaneously deployed to train the modified U-net. 200 raw images with a high resolution of 4928 × 3264 are collected, 160 for training and the rest 40 for the test. 512 × 512 patches are generated from the original images by a sliding window with an overlap of 256 as inputs. Results show that the average IoU between the recognized and ground-truth cracks reaches 0.409, which is 29.8% higher than the regular U-net. A five-fold cross-validation study is performed to verify that the proposed method is robust to different training and test images. Ablation experiments further demonstrate the effectiveness of the proposed SASA neuron and CRED algorithm. Promotions of the average IoU individually utilizing the SASA and CRED module add up to the final promotion of the full model, indicating that the SASA and CRED modules contribute to the different stages of model and data in the training process.

• Communications of the Korean Mathematical Society
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• v.38 no.1
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• pp.97-112
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• 2023

In this paper, we introduce and study the u-S-weak global dimension u-S-w.gl.dim(R) of a commutative ring R for some multiplicative subset S of R. Moreover, the u-S-weak global dimensions of factor rings and polynomial rings are investigated.