• Journal of Ginseng Research
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• v.32 no.2
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• pp.107-113
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• 2008

In this study, we have investigated the effect of panaxatriol (PT) on phosphoinositides (PIS) breakdown and $Ca^{2+}$-elevation in thrombin-induced platelet aggregation. Thrombin (5U/ml), a potent platelet agonist which activates phospholipase $C_{\beta}$ via protease activated receptor (PAR), hydrolyzed PIS in platelet membrane. The phosphatidylinositol 4, 5-bisphosphate $(PIP_2)$ was hydrolyzed after 10 sec of the thrombin-stimulation, and both the phosphatidylinositol 4-monophosphate (PIP) and phosphatidylinositol (PI) were brokendown after 30 sec of the thrombin-stimulation. However, PT inhibited the thrombin-stimulated hydrolysis of $PIP_2$, PIP, and PI. On the other hand, thrombin increased the level of phosphatidic acid (PA) which is phosphorylated from diacylglycerol (DG) generated by PIS-hydrolysis. However, Pr inhibited the thrombin-increased PA level non-significantly. Thrombin increased cytosolic free $Ca^{2+}([Ca^{2+}])_i$) up to 72% as compared with control $(30.8{\pm}0.9 nM)$ in intact platelet. However, PT (100 ${\mu}g/ml$) inhibited the thrombin-elevated $[Ca^{2+}]_i$ to 100%. These results suggest that PT may have a beneficial effect on platelet aggregation-mediated thrombotic disease by inhibiting thrombin-induced platelet aggregation via suppression of the $[Ca^{2+}]_i$ level and PIS breakdown.

• Journal of Radiation Protection and Research
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• v.17 no.1
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• pp.57-70
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• 1992

An excess risk of lung cancer mortality among Koreans, attributable to indoor $^{222}Rn$ daughters exposure, were quantitatively evaluated by applying a stochastic health risk projection model on the radiation exposure. The lung cancer rate in Korean males and females, based on the 1989 demographic data, were estimated to be $22.4/10^5-y\;and\;9.5/10^5-y$, respectively The lifetime baseline lung cancer risks, deduced from these rates, appeared to be 0.047 and 0.019 for males and females, respectively, and were lower than the corresponding 1984 values of 0.067 and 0.025 in the U.S.A. The excess risk coefficients, derived by modified relative risk projection model of the BEIR-IV Committee under the US National Academy of Science, per annual 1.0 WLM of exposure to indoor radon daughters were estimated to be 0.022/WLM for males, 0.009/WLM for females, and 0.017/WLM for both sexes. The resulting annual frequency of excess lung cancer mortality for the life expectancy in the Korean population appeared to be 230/10^6-WLM, which was an approximate median of $120{\sim}450/10^6-WLM$ reported so far in the world.

• Journal of Society of Preventive Korean Medicine
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• v.8 no.1
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• pp.89-107
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• 2004

This study was conducted to analyze community residents' behavior of Oriental medicine utilization and its related factors in order to provide basic data for formulation of policies on Oriental medicine. The subjects of this study was 500 residents who lived in big or medium sized cities and towns or villages Data were collected from March, 2002 to June, 2002. The results of this study can be summarized as follows. 1) According to socio-demographic characteristics of the respondents, female was 50.3%; 'over 50 years old' 29.9%, 'over college graduate' 39.7%, 'housewife' 23.0%, 'having spouse' 62.1%, 'Buddhist' 50.8%, 'living in big cities' 59.0%, 'middle economic class' 88.1%. 2) The highest proportion of frequency of Oriental medicine utilization was over 10 times(32.5%). The respondents visited Oriental medicine institutions for taking invigorant(51.1%), treatment of diseases in muscle or bone system(30.8%), treatment of diseases in digestive system(6.3%), etc. 3) According to the reasons of utilizing Oriental medicine, the proportion of good effect was highest(36.3%). 66.8% of the respondents replied that Oriental medical fee was expensive, while 0.8% of them replied that it was not expensive. 33.3% of them thought it was proper. 4) 35.5% of the respondents replied that treatment by Oriental medicine could cause side effect and 40.3% of them replied that the side effect could be caused by taking herb medicine. 5) 62.8% of the respondents replied that they would continuously receive opinions on Oriental medicine. The score of knowledge level of treatment by Oriental medicine $6.25{\pm}2.82$ points on the basis of 14 points. 6) The variables significantly influencing utilization of Oriental medicine includes taking diseases, living in big cities, male, upper (economic class, having religion, and effect of Oriental medicine. 7) The factors affecting effect of herb medicine were effect of treatment by Oriental medicine, marital status, knowledge level of Oriental medicine, having diseases, and frequency of receiving the treatment.

• The Korean Journal of Emergency Medical Services
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• v.12 no.3
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• pp.115-127
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• 2008

Purpose : This study aimed to examine the effects of empowerment of the paramedics on critical thinking and provide the basic materials for the qualitative improvement of emergency medical service. Methods : This study collected data with the paramedics working at general hospital and hospital emergency room in G metropolitan city, B metropolitan city, U metropolitan city, D metropolitan city and J province from July 1 to 31, 2008. Total 180 questionnaires were collected and 152 were used for final analysis, and the following results were obtained through statistical analysis using SPSS 12.0 program. Results : 1) Average score of empowerment was 4.44 out of 6 and according to average score by areas, significance was 4.94, capacity 4.92, self-determination 4.28, and effective-ness 3.62. 2) Empowerment by general characteristics was statistically significant in age (F = 3.313, p < 0.05), the final scholastic attainments(F = 2.436, p < 0.05), and salary(F = 1.695, p < 0.01). 3) Average score of critical thinking was 3.12 out of 7 and according to scores by areas, maturity was highest as 3.71, followed by no prejudice as 3.70, systemicity as 3.14, pursuit of truth as 3.05, much curiosity as 2.93, critical thinking and self-confidence as 2.92, and analysis as 2.91. 4) Critical thinking by general characteristics was statistically significant in marital status (F = 15.695, p < 0.01) and the final scholastic attainments (F = 2.606, p < 0.05). 5) Correlations between empowerment and critical thinking showed positive correlations as Pearson's correlation coefficient r = 0.400 and positive correlation in all areas including empowerment and critical thinking were found (r = 0.116-0.710). 6) The effect of empowerment on critical thinking was statistically significant in p < 0.01 and was explained as $R^2=0.155$. In the effects of empowerment on critical thinking, significance, capacity and self-determination were statistically significant in p < 0.01, effectiveness in p < 0.05 and were explained as R2 = 0.244. Conclusion : From the above results, it was found that empowerment had the influence on critical thinking, so it was considered that hospital managers and emergency room chiefs must develop and operate education and training program based on the concept of empowerment, maintenance and management strategies.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.2
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• pp.805-812
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• 2011

The elderly population has been dramatically increasing over the past years, but most of the population has developed chronic diseases and handicaps due to aging. High-intensity resistance training is one of the most effective ways to improve muscular strength, but it is unclear whether body composition and functional fitness would be increased by high-intensity resistance training. The aim of this investigation was to explore whether 12 weeks of high-intensity training would improve muscular strength, body composition, and functional fitness in women over the age of 70 years. Twenty-four participants were randomly assigned to a high-intensity resistance training group (n=8), a low-intensity resistance training group (n=8), and a control group (n=8). The experimental groups exercised 3 days per week for 12 weeks at a local fitness center. An analysis of variance(ANOVA) with repeated measures was used for analysis. The results showed that there was a significant improvement in agility and muscular strength following the high-intensity resistance training. Moreover, Moreover, %body fat and body fat mass decreased significantly after the 12 weeks of high-intensity resistance training(p<0.05). Based on these results, it was concluded that high-intensity resistance training is efficient for women over the age 70 years in increasing their muscular strength and functional fitness and reducing their total body fat mass.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.7B
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• pp.795-805
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• 2011

The research on the immersive media technology is actively being done with the emergence of immersive services using immersive media, especially in the broadcasting industry and with the increased market demand for it. The industry which produces, transmits, processes and services the immersive contents is commonly called Immersive Media Industry. Immersive Media Industry has recently received attention as next-generation strategic industry with its high marketability and its high possibility of market expansion through convergence with other industry such as education, health, advertisement, travel and public service industry. As other advanccd country such as the U.S., Japan and Europe buckle down to take the innitiative in the immersive media industry, Korea government also begins to make plan to promote the immersive media industry. As above, immersive media industry is a cutting-edge convergence industry which embraces broadcasting, telecommunication and contents industry and it is rising as core growth engine industry. This article analyses the economic effects of immersive media industry through quantatitive method and evaluates the relations between the immersive media industry and the other related industries. As a result, the effect on production inducement of immersive media industry is 610.9 billion Korean Won; the effect on value-added inducement is 468.7 billion Korean Won; and it is measured that 3,258 job will be created by the immersive media industry.

• Journal of the Institute of Convergence Signal Processing
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• v.20 no.1
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• pp.16-23
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• 2019

Fine particulate matter known as PM 2.5 refers to the atmospheric particulate matter that has a diameter less than 2.5 micrometer identified as dangerous element for human health and its concentration can provide us a clear picture about air dust concentration. Humans stay indoor almost 90% of their life time and also there is no official indoor dust concentration data, so our study is focused on measuring the indoor air quality. Indoor dust data monitoring is very important in hospital environments beside that other places can also be considered for monitoring like classrooms, cements factories, computer server rooms, petrochemical storage etc. In this paper, visible light communication system is proposed by Manchester encoding technique for electromagnetic interference (EMI)-free indoor dust monitoring. Important indoor environment information like dust concentration is transferred by visible light channel in wide range. An average voltage-tracking technique is utilized for robust light detection to eliminate ambient light and low-frequency noise. The incoming light is recognized by a photo diode and are simultaneously processed by a receiver micro-controller. We can monitor indoor air quality in real-time and can take necessary action according to the result.

• Parasites, Hosts and Diseases
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• v.49 no.3
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• pp.331-335
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• 2011

A tick survey was conducted to determine the relative abundance and distribution of ticks associated with selected mammals in the Republic of Korea (ROK) during 2008-2009. A total of 918 ticks were collected from 76 mammals (6 families, 9 species) captured at 6 provinces and 3 Metropolitan Cities in ROK. Haemaphysalis longicornis (54.4%) was the most frequently collected tick, followed by Haemaphysalis flava (28.5%), Ixodes nipponensis (7.6%), Ixodes pomerantzevi (4.8%), Ixodes persulcatus (4.6%), and Haemaphysalis japonica (0.1%). Adults (57.0%) and nymphs (28.7%) of Ixodes and Haemaphysalis spp. were collected most frequently from medium or large mammals in this survey, while few larvae (14.3%) were collected. Hydropotes inermis was the most frequently captured mammal (52.6%), with a 16.4 tick index and 5 of 6 species of ticks collected during this survey. H. longicornis (69.7%) was the predominant tick collected from H. inermis, followed by H. flava (22.2%), I. persulcatus (6.1%), I. nipponensis (1.8%), and H. japonica (0.2%).

• Journal of Preventive Medicine and Public Health
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• v.22 no.3 s.27
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• pp.328-336
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• 1989

27 shipyard welders were diagnosed as pneumoconiosis and suspected pneumoconiosis(1976-1988) by chest radiographs and were observed over three years. 27 welders were divided into three groups by the state of exposure to welding fume i.e. cessation, decresase or continuity of exposure. And we observed the changing pattern of the chest radiographs of 27 welders with the passage of time. The results were as follows; 1. Grour I (ceased exposure to welding fume) were 10 cases(3 cases: suspected pneumoconiosis,7 cases: pneumoconiosis). Chest radiographs of all cases were improved. The shape and size of small opacities was improved in 6 cases(85.7%) and did not changed in 1 case(14.3%) out of 7 pneumoconiosis welders. 2. Group II (decreased exposure to welding fume) were S cases(2 cases: suspected pneumoconiosis, 3 cases: pneumoconiosis). Chest radiographs were progressed in 2 cases(40%), did not changed in 1 case(20%), were improved in 2 cases(40%) out of 5 cases. The shape and size of small opacities was progressed in 1 case(33.3%) and was improved in 2 cases(66.7%) out of 3 pneumoconiosis welders. 3. Group III(continued expoxsure to welding fume) were 12 cases(1 case: suspected pneumoconiosis, 11 cases: pneumoconiosis). Chest radiographs were progressed in 9 cases(75%), did not changed in 3 cases(25%) out of 12 cases. The shape and size of small opacities was progressed in 1 case(9.1%) and did not changed in 10 cases(90.9%) out of 11 pneumoconiosis welders. 4. The average duration for development into suspected pneumoconiosis was 6.6 years and for progression of each one category after that was 2.2 years(p<0.01). The radiological appearance of pneumoconiosis had disappeared or decreased after cessation of exposure to the welding fume. So that, early detection and control e.g., change of department of pneumoconiosis of welders by screening program will be important for medical surveillance of welders.

• Korean Journal of Food Science and Technology
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• v.34 no.6
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• pp.1130-1133
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• 2002

Domoic acid, and amnesic shellfish poison, is a neurotoxin frequently found in shellfishes. Guidance level for the consumable shellfish has been established as $20\;{\mu}g$ domoic acid/g by Health and Welfare Canada and U.S. FDA. Domoic acid is produced by pennate diatom, a Nitzschia pungens f. multiseries ingested by the shellfish. Content of domoic acid in shellfish samples collected along the Korean shoreline from May to December of 1999 was analyzed. The collection included 1 Gastropoda (Murex shell) and 11 Bivalvias (oyster, little neck clam, orient hard clam, venus clam, surf clam, ark shell, hard-shelled mussel, pen shell, jack-knife clam, pink butterfly shell, and granulated ark shell). Samples were homogenized, extracted with 50% methanol, filtered, and analyzed by reversed-phase liquid chromatography at 242 nm with mobile phase consisting of 10% acetonitrile and 0.1% trifluoroacetic acid. Recovery of the HPLC analysis was 95.80% (${\pm}1.09$). All tested samples showed no domoic acid at the detection limit of 50 ng/g.