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The Weight Gain Effects of the Bofesungjangjeungbo-tang (Bǔfèichéngzhǎngzēngbǔ-tang) on Under-weight Korean Preschool Children with Frequent Common Cold or Chronic Rhinitis - Analysis of Medical Records - (잦은 감기나 만성 비염을 동반한 마른 체형 소아에 대한 보폐성장증보탕 (補肺成長增補湯)의 체중개선 효과 - 의무기록 분석 -)

  • Kim, Kijoon;Lee, Joonsuk;Yoon, Jihyun;Ryu, Bongha;Paik, Hee Young
    • The Journal of Pediatrics of Korean Medicine
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    • v.26 no.4
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    • pp.44-50
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    • 2012
  • Objectives: We investigated weight gain effects of the Bofesungjangjeungbo-tang ($B\check{u}f\grave{e}ich\acute{e}ngzh\check{a}ngz\bar{e}ngb\check{u}$-tang) on thin Korean preschool children with frequent common cold or chronic rhinitis Methods Bofesungjangjeungbo-tang was empirically composed of 14 herbs for treating indigestion, and common cold or chronic rhinitis. We analyzed 60 preschool children who have visited Kim Kijoon Oriental Clinic BOM from Jan. 1, 2006 to Aug. 31, 2011 with three criteria: 1) 2~5yrs of age and BMI<50th percentile 2) children those who had taken the Bofesungjangjeungbo-tang for 1~3 month (s), 3) Availability of records on before/after treatment within 3 months. Weight gain of the children after treatment was evaluated by the changes of BMI percentile compared to pre-treatment. Results Bofesungjangjeungbo-tang significantly improved BMI percentile in all groups (1 month: $21.33{\pm}10.04$ vs $26.43{\pm}13.16$, p<0.001; 2 months: $21.90{\pm}10.28$ vs $29.03{\pm}15.06$, p<0.001; 3 months: $19.06{\pm}10.04$ vs $35.71{\pm}17.40$, p=0.001). Gender, age and pre-treatment BMI had no significant effects on the effectiveness of Bofesungjangjeungbo-tang. Conclusions: Bofesungjangjeungbo-tang positively affected weight gain in 2~5yrs Korean preschool children with BMI below 50 percentile within 1~3 month (s) of treatment. However, additional studies on functional dyspepsia or the change of energy intake are needed to understand the factors related to weight gains.

Cross Affinity of Korean Weedy Rice to the Cultivars (국내 수집 잡초성 벼의 재배 품종에 대한 잡종 친화성)

  • Heu, Mun-Hue;Cho, Yong-Chul;Suh, Hak-Soo
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.35 no.3
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    • pp.233-238
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    • 1990
  • Weedy rice(red rice) collected in Korea were crossed with the Japonica, Javanica and Indica tester cultivars, and also crossed among those collected lines. Their seed fertility was counted and refered to their cross affinities. Some tester cultivars such as, Suweongjo, Malagkit Sinaguing and wx 817 which were regarded as belong to the Japonica, Javanica and Indica respectively, showed the typical tendencies of hybrid sterility when they were crossed each other. But, other testers such as Kwanak, Tapaiko, Belle Patna and Tarichaosun showed some differencies from those typical patterns, implying some varigations within a ecotype. The hybrids of weedy rice crossed to the Japonica testers showed higher fertility with a few semisterilities. While the crosses of weedy rice to the Javanicas or Indicas showed high sterility implying closer affinity relationships of weedy rice to the Japonicas. Even those weedy rice lines such as Samsanmyeon 8 and Sanchungaengmi B which showed semi-sterility when they were crossed to the Japonica testers showed high sterility when they were crossed to both Javanicas and Indicas. The hybrids among weedy rice lines showed high fertility raning 69% to 96%. Even those weedy rice lines which showed semi-sterility in the crosses with Japonica testers, showed high-fertility when they were crossed with those weedy rice lines. Though the amylose content, Alkali Digestive Value, Phenol reaction and grain shapes of theose weedy rice lines showed divers variations, the cross affinities of them showed closer phylogenie relationship to the Japonicas than to Japvanicas or Indicas. But the genetic influinces of Indicas to those weedy rices were not ignorable.

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Metal Reduction and Mineral formation by fe(III)-Reducing Bacteria Isolated from Extreme Environments (철환원 박테리아에 의한 금속 환원 및 광물형성)

  • Yul Roh;Hi-Soo Moon;Yungoo Song
    • Journal of the Mineralogical Society of Korea
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    • v.15 no.3
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    • pp.231-240
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    • 2002
  • Microbial metal reduction influences the biogeochemical cycles of carbon and metals as well as plays an important role in the bioremediation of metals, radionuclides, and organic contaminants. The use of bacteria to facilitate the production of magnetite nanoparticles and the formation of carbonate minerals may provide new biotechnological processes for material synthesis and carbon sequestration. Metal-reducing bacteria were isolated from a variety of extreme environments, such as deep terrestrial subsurface, deep marine sediments, water near Hydrothemal vents, and alkaline ponds. Metal-reducing bacteria isolated from diverse extreme environments were able to reduce Fe(III), Mn(IV), Cr(VI), Co(III), and U(VI) using short chain fatty acids and/or hydrogen as the electron donors. These bacteria exhibited diverse mineral precipitation capabilities including the formation of magnetite ($Fe_3$$O_4$), siderite ($FeCO_3$), calcite ($CaCO_3$), rhodochrosite ($MnCO_3$), vivianite [$Fe_3$($PO_4$)$_2$ .$8H_2$O], and uraninite ($UO_2$). Geochemical and environmental factors such as atmospheres, chemical milieu, and species of bacteria affected the extent of Fe(III)-reduction as well as the mineralogy and morphology of the crystalline iron mineral phases. Thermophilic bacteria use amorphous Fe(III)-oxyhydroxide plus metals (Co, Cr, Ni) as an electron acceptor and organic carbon as an electron donor to synthesize metal-substituted magnetite. Metal reducing bacteria were capable of $CO_2$conversion Into sparingly soluble carbonate minerals, such as siderite and calcite using amorphous Fe(III)-oxyhydroxide or metal-rich fly ash. These results indicate that microbial Fe(III)-reduction may not only play important roles in iron and carbon biogeochemistry in natural environments, but also be potentially useful f3r the synthesis of submicron-sized ferromagnetic materials.

Study of the Density of Smoke and Harmful Gases of Adhesive Indirect Moxibustion (접착식 간접구의 연기 밀도 및 유해가스 발생 확인 연구)

  • Kim, Eun-Jung;Kim, Yu-Jong;Hwang, Ji-Hoo;Cho, Hyun-Seok;Kim, Kyung-Ho;Lee, Seung-Deok;Kim, Kap-Sung
    • The Journal of Korean Medicine
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    • v.33 no.1
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    • pp.42-51
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    • 2012
  • Objectives: We measured the density of smoke and harmful gases emitted from burning adhesive indirect moxa. Through the test we aimed to find out if there was an excessive amount of smoke emitted and if it included harmful gases. Methods: 9 types of adhesive indirect moxa were chosen. The buffer layers which do not burn during treatment were removed and 10g of each moxa were made into powder and put into a holder. A smoke density chamber (Smoke Density Chamber FTT. U.K) and Fourier transform infrared spectroscopy (FT-IR I 4001. MIDAC U.S.A.) were used to measure the density of smoke and harmful gases emitted from burning moxa by ISO 5659-2 test. Results: The result of measuring maximum smoke density showed that the regular indirect adhesive moxa (A-F) emitted high density smoke of 172.1-291.4Ds. The smokeless moxas, Seoam moxas, emitted the least amount of 3.4-5.5Ds. Concentrations of 7 typical harmful gases (CO, HCl, HCN, HBr, HF, SO2, NOx) were measured and all of the moxas emitted CO due to incomplete combustion. 4 types of moxa emitted NOx and all smokless moxas emitted NOx. HBr, HCN, HCl, HF, SO2 were not found in any of the moxas. Conclusions: The amount of harmful gases emitted from burning moxa was much lower than short-term exposure standards of chemical and physical factors (Ministry of Labor 2010-44). Further experiments measuring gases from moxa combustion should be done in larger environments similar to normal medical clinics.

핵심 잡지의 결정 요인에 관한 연구

  • 김선호
    • Journal of the Korean Society for information Management
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    • v.5 no.1
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    • pp.53-78
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    • 1988
  • The purpose of this study is to verify the factors determining core journals in a field based upon the results of the citation analysis of the journals in the field of Korean History(KH). In order to verify the determinant factors, dividing the articles of the KH journals into their novelty and author's seniority, the following hypotheses were established. Hypothesis 1: When a KH journal publishes more articles on prehistoric and ancient eras than others, the journal will have higher chance to be included in the core journals. Hypothesis 2: When a KH journal publishes more articles by senior researchers than others, the journal will have higher chance to be included in the core journals. To achieve the purpose, the cited articles found in the two sample journals, namely, Backsan Hakbo and Hanguksa Yongu were analysed during the past 20 years from 1962 to 1981. Applying the Hirst's Discipline Impact Factor method to the the study, Historical Science Impact Factor(HSIF) on the samples itself and the historical era dealt with in the articles and the seniority of the authors during every five-year period. Based upon thr present study to ver~fy the two hypotheses, the following conclusions have been reached. 1) Tht. most influencing sublect mattcr era or1 thix liSIF of the lo~lrual is arranged in prehistoric arid ancient, Koryo, Chosun, recent era, and the others by order of era. 2 ) Clial~g~~lg a fringe or semicore journal u~to a core j ~ u r n a l , very IISIF' 011 it> article e r a 1s grown up arrd prcllistoric a ~ ~ d ancierlt era:. are, s p c c ~ a l l ~ , incr.eased high relatively. Char~ging a core journal int:~ a fr~ngr or semicort. journal, t.very IISIF ti dropped and prel~istc~ric and ancieut taras arc, fallen sharp relatively. 3) The most irlflr~encin~ s~niority 011 the t1SII- of ihc journal I. the senior.., written or1 prehistoric and ancient eras. Above all, the senilir'b HSIF olr prehistoric anti anclent e r a s a r e most ~nfluencing the cliangi~rg of the core journal into the fringe ur bemicore. .i) flypothesis fl is no1 vcrif~ed i r t general. T l ~ e rt, lative connections bet wee^^ the senior's HSIF 011 each era and tht, ~ l ~ a l ~ g i t l g of the tort. ji1ur.tia1 arc \:er~fied in part hut r~ot in the wliole. 5) 'The reason why the 11SIF or1 prehistori~. arid ar~cic~nt e r a s is higl~er than others can be assumed becaltic the new <, xcavations a r r contit~ued actively i l l the prrsr.llt as to the relics arid remains or1 that eras. Accordingly, the HSIF' r i l l thr 11ew 3ubject matter l~ke arcl~acmlogy trends to grow up greatly. Bctween the senior's and juriior's JISIE', junior'.; is higl~er than s., nior's except ancient e r a . That reason can be assumed bccausr Iunlorb t r j to solve the ex~sting problems thr~urglr their ow11 new viewpoints and sights. So, i t should be studied whether the 11SlF on the artic1t.s of the new subject matters and viewpoirrts is influenced to the changing of the core jorlrnal or not.

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Statistical Optimization for Production of Carboxymethylcellulase from Rice Hulls by a Newly Isolated Marine Microorganism Bacillus licheniformis LBH-52 Using Response Surface Method (통계학적인 방법과 왕겨를 기질로 사용하여 해양에서 분리한 Bacillus licheniformis LBH-52 를 사용한 carboxymethylcellualse의 생산조건 최적화)

  • Kim, Hye-Jin;Gao, Wa;Chung, Chung-Han;Lee, Jin-Woo
    • Journal of Life Science
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    • v.21 no.8
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    • pp.1083-1093
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    • 2011
  • A microorganism utilizing rice hulls as a substrate for the production of carboxymethylcellulase (CMCase) was isolated from seawater and identified as Bacillus lincheniformis by analyses of its 16S rDNA sequences. The optimal carbon and nitrogen sources for production of CMCase were found to be rice hulls and ammonium nitrate. The optimal conditions for cell growth and the production of CMCase by B. lincheniformis LBH-52 were investigated using the response surface method (RSM). The analysis of variance (ANOVA) of results from central composite design (CCD) indicated that a highly significant factor ("probe>F" less than 0.0001) for cell growth was rice hulls, whereas those for production of CMCase were rice hulls and initial pH of the medium. The optimal conditions of rice hulls, ammonium nitrate, initial pH, and temperature for cell growth extracted by Design Expert Software were 48.7 g/l, 1.8 g/l, 6.6, and 35.7$^{\circ}C$, respectively, whereas those for the production of CMCase were 43.2 g/l, 1.1 g/l, 6.8, and 35.7$^{\circ}C$. The maximal production of CMCase by B. lincheniformis LBH-52 from rice hulls under optimized conditions was 79.6 U/ml in a 7 l bioreactor. In this study, rice hulls and ammonium nitrate were developed to be substrates for the production of CMCase by a newly isolated marine microorganism, and the time for production of CMCase was reduced to 3 days using a bacterial strain with submerged fermentation.

The Fluorescence Behavior of the Responsive Macrocycle by Aromatic Imine Molecules

  • Choi, Chang-Shik;Jeon, Ki-Seok;Lee, Ki-Hwan
    • Journal of Photoscience
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    • v.11 no.32
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    • pp.71-74
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    • 2004
  • The macrocycle L exhibited a switch on-off behavior through the fluorescent responses by aromatic imine molecule 1 (X=H) / trifluoroacetic acid (TFA). In the 'switch on' state, it was supposed that the aromatic imine molecule 1 is in the cavity of macrocycle L and a photoinduced electron transfer (PET) from the nitrogen of azacrown part to the anthryl group is inhibited by the interaction between the aromatic imine molecule 1 and the azacrown part of macrocycle L. In the 'switch off' state, it was supposed that the protonated imine molecule 1 is induced by the continuous addition of TFA and a repulsion between the protonated azacrown part and the protonated imine molecule 1 is occurred. It was considered that this process induces the intermolecular PET from the protonated imine molecule 1 to the anthryl group of macrocycle L because of a proximity effect between the anthryl group and the protonated imine molecule 1. From the investigation of the transient emission decay curve, the macrocycle L showed three components (3.45 ns (79.72%), 0.61 ns (14.53%), and 0.10 ns (5.75%). When the imine molecule 1 was added in the macrocycle L as molar ratio=1:1, the first main component showed a little longer lifetime as 3.68 ns (82.75%) although the other two components were similar as 0.64 ns (14.28%) and 0.08 ns (2.96%). On the contrary, when the imine molecule 3 (X=C1) was added in the macrocycle L as molar ratio=l:1, all the three components were decreased such as 3.27 ns (69.83%), 0.44 ns (13.24%), and 0.06 ns (16.93%). The fluorescent pH titration of macrocycle L was carried out from pH=3 to pH=9. The macrocycle L and C $U^{2+}$- macrocycle L complex were intersected at about pH=5, while the E $u^{3+}$ -macrocycle L complex was intersected at about pH=5.5. In addtion, we investigated the fluorescence change of macrocycle L as a function of the substituent constant ($\sigma$$_{p}$$^{o}$) showing in the para-substituent with electron withdrawing groups (X=F, Cl) and electron donating groups (X=C $H_3$, OC $H_3$, N(C $H_3$)$_2$), respectively, as well as non-substituent (X=H).).ctively, as well as non-substituent (X=H).

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A study of museum of contemporary art in Germany (독일 현대미술관 연구)

  • Yoo Jae-Kil
    • Journal of Science of Art and Design
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    • v.7
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    • pp.105-127
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    • 2005
  • This research is on the characteristics and roles of important cities of Germany based on the history of the modern art museum and its possessions. Especially, it is focusing on the modern art museums in the western Germany including Dusseldorf, Koln, and Frankfrut that have shown economic recovery from the Miracle of Rhine; the capital city of Germany, Berlin, as well as Munich, the second capital city of Germany. Here, it harmonizes with the tradition of the past and simultaneously, it spreads the concept and role of the new museum as a forerunner. After the WWII, this is the most active of supporting investment for art museums and authors from the economic development. Also, it represents Germany with its national promotion of culture and arts. The modern art museums of Germany emphasize the mission that they exist for the people and the nation as well as creation of new art culture. These art museums working for national culture and art development do not simply collect and preserve arts. They induce active involvement from the public and keep in mind of national objectives. Here, art museums become and educational setting for the people and a room for new art culture. This research is on Germany modern art museum and it is composed of important 'public institutions' of Germany that critically influence the growth of world-renown authors. After the unification of Germany, Munchen and the western region became an important places centering around new Berlin modern art museum. They are the best places that show the national objectives and regional characteristics. Also, there are art museum educational curriculum and open space for the people by explaining exhibition plans and contents. Furthermore, there are two characteristics of German modern art museums that are noteworthy. Firstly, there are Berlin's Neue Nationalgalerie, Munchen's Pinakothek de Moderne, and Dusseldorf's 'K20' (Kunstsammlung N-Westfalen K20) that are the roots of modern art. These modern art museums exhibit popular author's collection repeatedly. This has a tendency to standardize audiences' view or to make audiences bored. It is becoming more like a trend for art work to appear and disappear. Despite these problems, German modern art museums play a critical role for a new cultural art creation and for the national identity by attempting to show the works of domestic authors as well as an intensive collection of world-renown authors' works. Secondly, there is a role as a new art museum to work together with people. It strives to continuously educate difficult modem arts, exhibits in an open space stimulating interest, participation, and conversations. From these roles, Hamburger Bahnhof Museum fur Gegenwart or Dusseldorf's 'K21, Frankfurt Museum $f\"{u}r$ Moderne Kunst, $Kf\"{o}ln$ Museum Ludwig are given new attention. Here, they emphasize the importance of communicating with the audiences and provides experiences that are different from the original spaces by showing the architecture tecture style of the art museum. In conclusion, German modern art museums attempt various changes by connecting to art education. With art museum activities, there forms a connection between arts and the lives of people, and from this, creative cultural art focused on the art museum borns. This is not only limited to Germany, the U.S., etc. We, too, should pay attention to new art culture creation from changes of role and function of modern art museums.

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THE EFFECTS OF SURFACE CONTAMINATION ON THE SHEAR BOND STRENGTH OF COMPOMER

  • Heo, Jeong-Moo;Lee, Su-Jong;Im, Mi-Kyung
    • Proceedings of the KACD Conference
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    • 2001.11a
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    • pp.577-577
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    • 2001
  • The lastest concepts in bonding are "total etch", in which both enamel and dentin are etched with an acid to remove the smear layers, and "wet dentin" in which the dentin is not blown dry but left moist before application of the bonding primer. Ideally, the application of a bonding agent to tooth structure should be insensitive to minor contamination from oral fluids. Clinically contaminations such as saliva, gingival fluid, blood and handpiece lubricant are often encountered by dentists during preparation of a restoration. The aim of this study was to evaluate the effect of contamination by hem-ostatic agents on shear bond strength of compomer restorations. One hundred and ten extracted human maxillary and mandibular molar teeth were collected. The teeth were cleaned from soft tissue remnant and debris and stored in physiologic solution until they were used. Small flat area on dentin of the buccal surface were wet ground serially with 400, 800 and 1200 abrasive paper on automatic polishing machine. The teeth were randomly divided into 11 groups. Each group was conditioned as follows: Group 1 : Dentin surface was not etched and not contaminated by hemostatic agents. Group2 : Dentin surface was not etched but was contaminated by Astringedent (Ultradent product Inc., Utah, U.S.A.). Group3 : Dentin surface was not etched but was contaminated by Bosmin (Jeil Phann, Korea.). Group4 : Dentin surface was not etched but was contaminated by Epri-dent (Epr Industries, NJ, U.S.A.). Group5: Dentin surface was etched and not contaminated by hemostatic agents. Group 6 : Dentin surface was etched and contaminated by Astringedent. Group7 : Dentin surface was etched and contaminated by Bosmin. Group8 : Dentin surface was etched and contaminated by Epri-dent. Group9 : Dentin surface was contaminated by Astringedent. The contaminated surface was rinsed by water and dried by compressed air. Group10 : Dentin surface was contaminated by Bosmin. The contaminated surface was rinsed by water aud dried by compresfed air. Group 11 : Dentin surface was contaminated by Epri-dent. The contaminated surface was rinsed by water and dried by compresfed air. After surface conditioning, F2000 was applicated on the conditoned dentin surface. The teeth were thermocycled in distilled water at $5^{\circ}C\;and\;55^{\circ}C$ for 1000 cycles. The samples were placed on the binder with the bonded compomer-dentin interface parallel to the lmife-edge shearing rod of the Universal testing machine(Zwick 020, Germany) running at a cross head speed of 1.0mmimin. There were no significant differences in shear bond strength between groups 1 and group 3 and 4, but group 2 showed significant decrease in shear bond strength compared with group 1. There were no significant differences in shear bond strength between group 5 and group 7 and 8, but group 6 showed significant decrease in shear bond strength compared with group 5. There were no significant differences in shear bond strength between group 5 and group 9, 10 and 11.

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Syntheses and Solvolysis of Biological Active 1-(Methacryloyloxymethyl)-5-fluorouracil and Its Polymers (생물활성을 갖는 1-메타크릴로일옥시메틸-5-플루오로우라실 및 그 중합체의 합성과 가용매반응)

  • Lee, Neung-Ju;Oh, Sang-Hoon;Ha, Chang-Sik;Lee, Jin-Kook;Cho, Won-Jei
    • Applied Chemistry for Engineering
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    • v.1 no.2
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    • pp.190-196
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    • 1990
  • The biological active monomer, 1-(methacryloyloxymethyl)-5-fluorouracil(MAOMFU) was synthesized from 2, 4-bis(trimethylsilyloxy)-5-fluoropyrimidine. Poly(MAOMFU) poly(1-methacryloyloxymethyl-5-f1uorouracil-co-methyl methacrylate), and poly(MAOMFU-co-MMA) were also obtained by radical polymerization at $60^{\circ}C$. The monomer reactivity ratios, $r_1$ and $r_2$ were determined by $Kelen-T\ddot{u}d\ddot{o}s$ method ; $r_1(MAOMFU)=0.72$, and $r_2(MMA)=1.24$. These reactivity values imply that the copolymerization was mainly affected by the steric hindrance of MAOMFU. It was found from kinetic measurements that the rate constants of solvolysis are given as $6.42{\times}10^{-5}sec^{-1}$ and $7.40{\times}10^{-6}sec^{-6}$, respectively, for MAOMFU and poly(MAOMFU).

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