• The Korean Journal of Pharmacology
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• v.32 no.1
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• pp.39-49
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• 1996

In the present study, we observed change in intracellular $Ca^{2+}$$([Ca^{2+}]_i)$ as measured with the fluorescent $Ca^{2+}-indicator$ fura-2 in association with force development of the rat basilar arteries during activation by$K^+$ depolarizing solution and U46619, a thromboxane analogue, in the absence and the presence of calcitonin-gent related peptide (CGRP). CGRP (30 and 100 nM) caused a concentration-dependent inhibition of U46619-induced contraction with decrease in $[Ca^{2+}]_i$, whereas it did not exert any effect on the $K^+$ (90 mM)-induced contraction and increase in $[Ca^{2+}]_i$, Further, $[Ca^{2+}]_i-force$ relationships were determined by plotting the ratio of $F_{340}/F_{380}$ $([Ca^{2+}]_i)$ as a function of the force induced by U46619, and the results were compared with those obtained in the presence of CGRP. The curves obtained in the presence of CGRP (30 and 100 nM) were significantly moved to downward without right shift of the curves suggesting that CGRP inhibited the U46619-induced contraction only by mediation of reduction in $[Ca^{2+}]_i$ with out any change in the sensitivity of contractile apparatus to $Ca^{2+}$. The CGRP-induced attenuation of $[Ca^{2+}]_i$ and force development was significantly inhibited under pretreatment with CGRP $(8{\sim}37)$ fragment (100 nM), a CGRP1 receptor antagonist. Both the reduced contraction and reduction in $[Ca^{2+}]_i$ caused by CGRP were fully reversed by pretreatment with charybdotoxin (100 nM) and iberiotoxin (100 nM), large conductance $Ca^{2+}-activated$ $K^+$ channel blockers, but not by apamin (300 nM), a small conductance $Ca^{2+}-activated$ $K^+$ channel blocker, and glibenclamide ( 1 ${\mu}M$), an ATP-sensitive $K^+$ channel blocker. In conclusion, it is suggested that the CGRP1 receptor, upon activation by CGRP, are coupled to opening of $Ca^{2+}-activated$ $K^+$ channel and cause to decrease in $[Ca^{2+}]_i$, thereby leading to vasodilation of the rat basilar artery. However, it is not defined that the mechanism underlying vasodilation whether the $K^+$ channel blockers, charybdotoxin and iberiotoxin directly block the CGRP receptors and that CGRP-evoked relaxation is dependent on the cyclic AMP or $K^+$ channel opening or both actions.

• Bulletin of the Korean Mathematical Society
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• v.53 no.1
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• pp.163-180
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• 2016

We study the structure of an arbitrary graded Lie triple system $\mathfrak{T}$ with restrictions neither on the dimension nor the base field. We show that $\mathfrak{T}$ is of the form $\mathfrak{T}=U+\sum_{j}I_j$ with U a linear subspace of the 1-homogeneous component $\mathfrak{T}_1$ and any $I_j$ a well described graded ideal of $\mathfrak{T}$, satisfying $[I_j,\mathfrak{T},I_k]=0$ if $j{\neq}k$. Under mild conditions, the simplicity of $\mathfrak{T}$ is characterized and it is shown that an arbitrary graded Lie triple system $\mathfrak{T}$ is the direct sum of the family of its minimal graded ideals, each one being a simple graded Lie triple system.

• YAKHAK HOEJI
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• v.6 no.1
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• pp.28-34
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• 1962

Oxytocin and vasopressin were extracted from bovine posterior pituitaries and assayed, in many ways. On the assay of oxytocic active substance, it was found the depression method of blood pressure in a chicken was the easiest one among possible methods. The potency of oxytocin which was extracted with glacial acetic acid was 14.2 I.U./mg. On the assay of vasopressin for pressor activity. A full grown healthy male rat was used. Applying a simple artificial respiratory apparatus, the assay could be carried out successfully. The potency of vasopressin was 13.2 I.U/mg.

• Speech Sciences
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• v.7 no.3
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• pp.99-108
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• 2000

The purpose of this experimental study was to investigate characteristics of English vowels as spoken by Korean speakers. Ten English mono-syllabic words were spoken six times by six male college students who were born and raised in Seoul. Formant frequencies were measured from sound spectrograms made by the PC Quirer. Results showed that Korean speakers similarly pronounced /i/ and /I/, /u/ and /$\upsilon$/, and /$\varepsilon$/ and /${\ae}$/ respectively. It seems that Korean speakers can not differentiate tense vowels(/i/, /u/) from lax vowels(/i/, /$\upsilon$/) and pronounce low vowels such as /${\ae}$/, /a/, /c/ clearly. It is necessary that Korean speakers practice the correct movements of the jaw, tongue, and lips when they pronounce English vowels.

• Speech Sciences
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• v.8 no.4
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• pp.193-206
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• 2001

The purpose of this experimental study was to investigate characteristics of English vowels uttered by Korean regional dialect speakers. Ten English mono-syllabic words, and eight Korean mono-syllabic words, were uttered six times by nine female graduate students from three areas: Seoul, Yongnam and Honam. Formant frequencies were measured from sound spectrograms made by the PC Quirer. Results showed that Seoul dialect speakers uttered English vowels more similar to those uttered by English native speakers than did the other dialect speakers. In particular, Yongnam dialect speakers have articulatory problems pronouncing the back vowels(/u/, /$\upsilon$/, /c/), while Honam dialect speakers have problems pronouncing the front vowels(/i/. /I/, /$\varepsilon$/, /$\ae$/). Even though each group has different problems pronouncing English vowels, Korean speakers generally have difficulty in discriminating tense vowels(/i/ and /u/) from the lax vowels(/I/ and /$\upsilon$/). It appears that the width of Korean speakers' articulatory movements is comparatively narrower than those of native English speakers.

• Journal of Elementary Mathematics Education in Korea
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• v.21 no.3
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• pp.485-503
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• 2017

'Saembon' was elementary mathematics textbook in the Period of Syllabus in Korea. First I classified Saembons in five groups. And then I regrouped them into two kinds. One kinds were published under U.S. Army Military Government, and other kinds were made under Republic of Koera. Two kinds of Saembon were very different in several aspects. I showed how they were different through real examples. Finally I tried to explain that Saembons under Republic of Koera were better than Saembons under U.S. Army Military Government.

• Management & Information Systems Review
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• v.21
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• pp.155-168
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• 2007

In the ubiquitous which is rapidly developing with ultra speed thes days, constructing the u-Campus which is using the sensor-network as its base is keep developing. Also, any information related equipments like PC and mobile, computing is possible whenever and wherever you want and due to the development of the wireless network, the service environment is continually developing. In this article, I'd like to suggest the u-Campus which is very suitable to the user's environment which had used application of mobile. In u-Campus, various techniques are adopted and applied along with development of info-communication related technidques. Especially, the new type of campus which is constructed by adopting the ubiquitous computing net-work technique to the campus of university is the u-Campus. In this article, by suggesting u-Yuhan designing methods, more effective and advanced school activities of students to make possible.

• Bulletin of the Korean Mathematical Society
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• v.22 no.1
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• pp.17-22
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• 1985

B.M. Munshi and D.S. Bassan defined and developed the concept of super continuity in [5]. The concept has been investigated further by I. L. Reilly and M. K. Vamanamurthy in [6] where super continuity is characterized in terms of the semi-regularization topology. Super continuity is related to the concepts of .delta.-continuity and strong .theta.-continuity developed by T. Noiri in [7]. The purpose of this note is to derive relationships between super continuity and other strong continuity conditions and to develop additional properties of super continuous functions. Super continuity implies continuity, but the converse implication is false [5]. Super continuity is strictly between strong .theta.-continuity and .delta.-continuity and strictly between complete continuity and .delta.-continuity. The symbols X and Y will denote topological spaces with no separation axioms assumed unless explicity stated. The closure and interior of a subset U of a space X will be denoted by Cl(U) and Int(U) respectively and U is said to be regular open (resp. regular closed) if U=Int[Cl(U) (resp. U=Cl(Int(U)]. If necessary, a subscript will be added to denote the space in which the closure or interior is taken.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.5 no.2
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• pp.91-101
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• 2007

In this study, domestic regulatory requirement was investigated for self-disposal of concrete waste from nuclear fuel processing facility. And after self-disposal as landfill or recycling/reuse, the exposure dose was evaluated by RESRAD Ver. 6.3 and RESRAD BUILD Ver.3.3 computing code for radiological assessments of the general public. Derived clearance level by the result of assessments for the exposure dose of the general public is 0.1071Bq/g (3.5% enriched uranium) for landfill and $0.05515Bq/cm^2$ (5% enriched uranium) for recycling/reuse respectively. Also, residual radioactivity of concrete waste after decontamination was investigated in this study. The result of surface activity is $0.01Bq/cm^2\;for\;{\alpha}-emitter$ and the result of radionuclide analysis for taken concrete samples from surface of concrete waste is 0.0297Bq/g for concentration of $^{238}U$, below 2w/o for enrichment of $^{235}U$ and 0.0089Bq/g for artificial contamination of $^{238}U$ respectively. Therefore, radiological hazard of concrete waste by self-disposal as landfill and recycling/reuse is below clearance level to comply with clearance criterion provided for Notice No.2001-30 of the MOST and Korea Atomic Energy Act.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.38
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• pp.265-302
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• 2008

This paper intends to analyse some legal issues on "Zeroing" which is based on the article 2.4.2 under the WTO Anti-dumping Agreement. "Zeroing" stands for a specific methodology in calculating a general dumping margin for a product in question under which negative individual dumping margins are treated as zero (thus "zeroed") before aggregating all individual dumping margins. The article 2.4.2 of the Anti-dumping Agreement regulates three types of calculating methodology on dumping margin as first symmetrical method(average-to-average: A-A), second symmetrical method(individual-to-individual: I-I) and asymmetrical method(average-to-individual: A-I). However, this article does not have any provisions about the "Zeroing" practice. In their anti-dumping practices, the EC and the United-States calculated dumping margin based on the "Zeroing", but this methodology has been disputed in the Dispute Settlement Body(DSB) of the WTO. This paper analysed their legal problems with some WTO cases in particular concerning EC-Bed Linen, U.S.-Softwood Lumber Zeroing, U.S.-Zeroing(EC) and U.S.-Sunset Review(Japan) cases. On the basis of theses analysis, we can therefore ask some questions as follows; To begin with, although the article 2.4.2 of the WTO Anti-dumping Agreement does not clearly refer to the "Zeroing", how do some developing countries, as the U.S.A and the E.U. calculate dumping margin as the "Zeroing"? Secondly, what is the relationship between the symmetrical method and asymmetrical method to the dumping margin? And if we adopt the zeroing method, what is the different rate to anti-dumping margin? Thirdly, although the Panel decided that the zeroing methodology of dumping margin used by th U.S.A in administrative review between the U.S.A and the E.U, why does the Appellate Body made the decision that the american methodology is incompatible with the WTO Anti-dumping Agreement? Lastly, what will be affected the upper decision taken by the Appellate Body to the DDA negotiation of anti-dumping matters? Even though the WTO Appellate made a decision that the zeroing method is incompatible with the principles of the WTO law, this methodology contains a lot of problems. Some members of the WTO as the U.S.A and the E.U did not officially declare this methodology to abandon, and the debate concerned is arguing. Therefore this paper tried to present the adequate solution in order to promote the zeroing methodology in the international anti-dumping system and practices.