• KSCE Journal of Civil and Environmental Engineering Research
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• v.36 no.6
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• pp.1117-1123
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• 2016

Roller-Compacted Concrete Pavement (RCCP) is a type of pavement that shares conventional concrete pavement material characteristics and asphalt pavement construction characteristics. Even though RCCP is compacted in the same way and have similar aggregate gradation to asphalt pavements, its materials and structural performance properties are similar to those of conventional concrete pavement. With cement hydration and aggregate interlock, Roller-Compacted Concrete or RCC can provide strength properties equal to those of conventional concrete with low cement content. Therefore, compaction ratio of RCC can highly influence on its strength. In general, 95% of compaction ratio is required for proper strength development. RCC strength can be highly influenced by compaction energy which depends on compaction equipment and compaction method. Therefore, it is necessary to analyze the relationship between compressive strength and compaction ratio of RCC. RCCP specimens were produced at different compaction ratio by using different compaction methods and energies. The compaction ratio was defined by the ratio of the specimen's dry density and its maximum dry density. The maximum dry density was obtained from Modified Proctor test. 28 days compressive strength corresponding to each compaction ratio case was tested. Finally, the relationship between compressive strength and compaction ratio can be analyzed. For application of roller-compacted concrete in domestic construction site, the relationship is important for field compaction management.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.10
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• pp.4177-4183
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• 2015

Background: Gastric cancer is the second leading cause of cancer-related death in Asia, and the majority type is gastric adenocarcinoma (GAC). Most GAC patients die of recurrence and metastasis. Cancer stem cells (CSCs) have been thought to be responsible for the initiation, development, metastasis, and ultimately recurrence of cancer. In this study, we aimed to investigate expression and clinical significance of CSCs markers, CD133 and Lgr5, and vasculogenic mimicry (VM) in primary GAC. Materials and Methods: Specimens from 261 Chinese patients with follow-up were analyzed for CD133, Lgr5 protein expression and VM by immunohistochemical and histochemical staining. The Pearson Chi's square test was used to assess the associations among the positive staining of these markers and clinicopathological characteristics. Postoperative overall survival time was were studied by univariate and multivariate analyses. Results: In GAC tissues, positive rates of 49.0%, 38.7%, and 26.8% were obtained for CD133, Lgr5, and VM, respectively. The mean score of microvessel density (MVD) was $21.7{\pm}11.1$ in GAC tissues. There was a significantly difference between the positive and negative groups. There was a positive relationship between the VM, the expression of CD133 and Lgr5, and the score of MVD and the grades of tumor, lymph node metastasis, TNM stages (all p<0.05). The overall mean survival time of the patients with CD133, Lgr5, VM, and MVD (${\geq}22$) positive expression was lower than that of patients with negative expression. The score of MVD, positive expression of CD133 and VM were independent prognostic factors of GAC (p<0.05). Conclusions: VM, and expression of CD133, Lgr5, and the score of MVD are related to grades of tumor, lymph node metastasis, TNM stages, and overall mean survival time. It is suggested that CSCs and VM could play an important role in the evolution of GAC.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.37
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• pp.2.1-2.9
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• 2015

Background: The aim of this study was to evaluate the effect of autogenous tooth bone as a graft material for regeneration of bone in vertical bony defects of the minipigs. Material and Methods: Six minipigs were used in this study. Four molars were extracted in the right mandibular dentition and sent to the Korea Tooth Bank for fabrication of autogenous tooth bone. Ten days later, each extraction site was implanted with MS Implant Narrow Ridge $3.0{\times}10mm$ fixture (Osstem, Seoul, Korea) after standardized 2mm-sized artificial vertical bony defect formation. Pineappleshaped Root-On type autogenous tooth bones were applied to the vertical defects around the neck area of the posterior three fixtures and the fore-most one was not applied with autogenous bone as a control group. Each minipig was sacrificed at 4, 8, 12 weeks after fixture installation and examined radiologically and histologically. Histological evaluation was done under light microscope with Villanueva osteochrome bone staining with semi-quantitative histomorphometric study. Percentage of new bone over total area (NBF) and bone to implant contact (BIC) ratio were evaluated using digital software for area calculation. Result: NBF were $48.15{\pm}18.02%$, $45.50{\pm}28.37%$, and $77.13{\pm}15.30%$ in 4, 8, and 12 weeks, respectively for experimental groups. The control group showed $37.00{\pm}11.53%$, $32.25{\pm}26.99%$, and $1.33{\pm}2.31%$ in 4,8,12 weeks, respectively. BIC ratio were $53.08{\pm}19.82%$, $45.00{\pm}28.37%$, and $75.13{\pm}16.55%$ in 4,8,12 weeks, respectively. Those for the control groups were $38.33{\pm}6.43%$, $33.50{\pm}29.51%$, and $1.33{\pm}2.31%$ in 4, 8, 12 weeks, respectively. Conclusion: Autogenous tooth bone showed higher score than control group in NBF and BIC in all the data encompassing 4,8,12 weeks specimens, but statistically significant only 12 weeks data in both NBF and BIC.

• Korean Journal of Microbiology
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• v.30 no.1
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• pp.15-29
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• 1992

Vibrio vuln$cus has been recognized as a pathogen of septicemia and wound infection, when the organism attacks high-risk persons with a history of hepatic disease. alcohol abuse. diabetes or any debilitative disease. Forty six strains of K vulnzjicus. isolated from 1025 marine specimens from May to Novemver for three years. from 1985 to 1987. were studied for their biochemical properties. growth requirements, serotype and drug susceptibilities. The isolates were different in their various biochemical reactions. Ninety-five percent of isolated strains were able to ferment lactose, while most strains didn't utilize sucrose in their biochemical test, for example ornithine, gelatin and mannitol were quite dit'ferent composition than those described in other reports. It was found that the biochemical test wasn't useful for identifying strain. The type of somatic 0 antiserum was determined in isolates from marine sources and in patients with Vibrio septicemia. In patient isolates. 1-2 group were 24% and 1-4 group were 42%. However. 02 group(33%) were more abundant in isolates from marine sources. Minimal inhibitory concentrations(M1Cs) of chloramphenicol, tetracycline. erythromycin and ampicillin were determinef for V vuln~ficus by broth dilution method. MIC90 was I , 0.25, :! and 4,ug/ml in patient isolates. 1, 0.25, 2 and 2 ,ug/ml in marine isolates. The divalent chelating agent, IDTA. inhibited the growth of V. vuln!'ficus at 6.25 mMlml of MIC90.

• Korean Journal of Materials Research
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• v.5 no.7
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• pp.888-896
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• 1995

In this paper the manufacture of shrinkage-free in situ Mullite-ZrO$_2$ceramics through the addition of Al base metal powder to the mixture of ZrSiO$_4$and A1$_2$O$_3$was attempt. The ZrO$_2$-strengthened mullite ceramics was prepared after the following reaction form, 3(Al+Al$_2$O$_3$)+2ZrSiO$_4$longrightarrow3A1$_2$O$_3$.2SiO$_2$+2ZrO$_2$Al metal powder was added from none to 30 weight percent to the A1$_2$O$_3$. The powders were mechanically mixed, isostatically pressed and reaction sintered at 1450-1$600^{\circ}C$ for 3hours. The specimens were sintered with and without intrim soaking time for 5 hours at 125$0^{\circ}C$ for the oxidation of Al-powder The addition of aluminium accelerates the reaction and compensate the shrinkage during the sintering through an increase in volume of oxidized Al. Because coarse flake type Al metal powders were not effectively milled, oxidized Al resulted in the relative large pore in the specimen.

• Korean Journal of Materials Research
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• v.8 no.9
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• pp.831-836
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• 1998

The B1914 Ni-base superalloy was manufactured according to crystal structures of poly-, directionally solidified- and single crystals. We observe deformation as type of different crystal structure from room to high temperature. Specimens are controled by cooling rate and thermal gradient and then heat treatment in vacuum and then cooling with Ar gas. Different crystal structure has different stress-strain characteristic. At $600^{\circ}C$, yield strength and ultimate strength is increased single-, directionally solidified- and poly crystals in order.

• Journal of the Korea institute for structural maintenance and inspection
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• v.24 no.2
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• pp.94-102
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• 2020

Precast concrete segment arch system has an economic and construct ability that combined with advantage of precast concrete and arch behavior. A precast concrete segment arch system with outrigger is consisted of segmented precast panels, a steel outrigger rib, and V-strip to connect precast panels with a steel outrigger rib and cast-in-place anchors in precast panels to connect V-strip should have sufficient pull-out capacity to form its arch shape by site lifting for assembled precast panels and outriggers. However, it is difficult to secure its embedment depth due to the relatively shallow thickness of precast panel. It can be also occurred that flexure deformation of precast panels caused by its pull-out behaviors. In this study, pull-out capacity of cast-in-place anchor was examined for construction of precast concrete segment arch system with outriggers. Therefore, a total of 24 precast panel specimens were fabricated to examine pull-out capacities of cast-in-place anchor in precast panels, and installation depth of anchors, diameter of anchors and wire mesh effects for the precast panel were examined. From this pull-out tests, its pull-out capacities and failure modes were evaluated and the type of the cast-in-place anchor applicable to the precast concrete segment panel arch system with outriggers was determined from comparison of the design specification values.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.6C
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• pp.213-220
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• 2011

Fines such as silt or clay are usually mixed with granular particles in natural or reclaimed soils which are slightly cemented. Such fines contained within weakly cemented soils may influence permeability and also mechanical behavior of the soils. In this study, a series of unconfined compression tests on weakly cemented sands with fines are carried out in order to evaluate the effect of fines on unconfined compressive strength (UCS) of cemented soils. Two different cement ratios and fine types were used and fine contents varied by 5, 10, and 15%. Two types of specimens were prepared in this testing. One is the specimen with the same compaction energy applied. The other is the one with the same dry density by varying compaction energy. When the same amount of compaction energy was applied to a specimen, its density increased as a fine content increased. As a result, the UCS of cemented soils with fines increased up to 2.6 times that of one without fines as an amount of fines increased. However, when the specimen was prepared to have the same density, its UCS slightly decreased and then increased a little as a fine content increased. Under the same conditions, a UCS of the specimen with silt was stronger than the one with kaolin. As a cement ratio increased, a UCS increased regardless of fine type and content.

• Archives of Plastic Surgery
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• v.42 no.6
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• pp.686-694
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• 2015

Background Rosa damascena, a type of herb, has been used for wound healing in Eastern folk medicine. The goal of this study was to evaluate the effectiveness of rose placenta from R. damascena in a full-thickness wound model in mice. Methods Sixty six-week-old C57BL/6N mice were used. Full-thickness wounds were made with an 8-mm diameter punch. Two wounds were made on each side of the back, and wounds were assigned randomly to the control and experimental groups. Rose placenta ($250{\mu}g$) was injected in the experimental group, and normal saline was injected in the control group. Wound sizes were measured with digital photography, and specimens were harvested. Immunohistochemical staining was performed to assess the expression of epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), transforming growth factor-${\beta}1$ (TGF-${\beta}1$), and CD31. Vessel density was measured. Quantitative analysis using an enzyme-linked immunosorbent assay (ELISA) for EGF was performed. All evaluations were performed on postoperative days 0, 2, 4, 7, and 10. Statistical analyses were performed using the paired t-test. Results On days 4, 7, and 10, the wounds treated with rose placenta were significantly smaller. On day 2, VEGF and EGF expression increased in the experimental group. On days 7 and 10, TGF-${\beta}1$ expression decreased in the experimental group. On day 10, vessel density increased in the experimental group. The increase in EGF on day 2 was confirmed with ELISA. Conclusions Rose placenta was found to be associated with improved wound healing in a mouse full-thickness wound model via increased EGF release. Rose placenta may potentially be a novel drug candidate for enhancing wound healing.

• Journal of Korean Society of Steel Construction
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• v.20 no.6
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• pp.701-709
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• 2008

Owing to the decreased work term and the convenience of construction work in Korea, the steel deck plate system has been widely used in the construction field. Most of all, due to its good stiffness and economic consideration, the steel-wire-integrated deck plate system (or truss deck plate system) has become very popular in recent years. But although it has many advantages, the truss deck plate system has a critical defect: it gets rusty in the welding joints between the lattice steel wire and the deck plate, resulting in the cracking of such welding joints and water leakage. To address these problems, a new type of truss deck plate system, which need not be welded and does not rust, was proposed herein: the TOX deck plate system. In this study, tests were conducted on 15 specimens to evaluate the structural safety of the proposed deck plate system during the construction stage. The test parameters were as follows: the depth of the slab the length of the span the diameters of the top, bottom, and lattice steel wire and the material properties of the zinc-coated steel sheets. The test results show that the TOX deck plate system can guarantee structural safety owing to its deflection and strength.