• Title/Summary/Keyword: Type I aB

Search Result 1,362, Processing Time 0.035 seconds

The Shigella Flexneri Effector OspG Interferes with Innate Immune Responses by Targeting Ubiquitin-Conjugating Enzymes

  • Kim, Dong-Wook
    • Proceedings of the PSK Conference
    • /
    • 2005.11a
    • /
    • pp.231-232
    • /
    • 2005
  • Bacteria of Shigella spp. are responsible for shigellosis in humans, a disease characterized by destruction of the colonic epithelium that is induced by the inflammatory response elicited by invasive bacteria. They use a type III secretion system injecting effector proteins into host cells to induce their entry into epithelial cells and triggers apoptosis in macrophages. We present evidence that the effector OspG is a protein kinase that binds various ubiquitinylated ubiquitin-conjugating enzymes (E2s) and blocks degradation of phospho-$I{\kappa}B{\alpha}$ induced upon entry of bacteria into epithelial cells. Transfection experiments confirmed that OspG interferes with the $NF-{\kappa}B$ activation patway by preventing phospho-$I{\kappa}B{\alpha}$ degradation, suggesting that OspG inactivates a component of the $SCF^{{\beta}-TrCP}$ ubiquitin ligase complex (E3) involved in phospho-$I{\kappa}B{\alpha}$ ubiquitination. Upon infection of ileal loops in rabbits, the ospG mutant induced a stronger inflammatory response compared with the wild-type strain, indicating that OspG down-regulates the host innate response induced by invasive bacteria.

  • PDF

Gold-Silver Mineralization of the Au-Ag Deposits at Yeongdong District, Chung-cheongbuk-Do (충청북도(忠淸北道) 영동지역(永同地域) 금은광상(金銀鑛床)의 금은광화작용(金銀鑛化作用)에 관한 연구(硏究))

  • Choi, Seon Gyu;Chi, Se Jung;Park, Sung Won
    • Economic and Environmental Geology
    • /
    • v.21 no.4
    • /
    • pp.367-380
    • /
    • 1988
  • Most of the gold (-silver) vein deposits at Yeongdong District are mainly distributed in the precambrian metamorphic rocks. Based on the Ag/Au total production and ore grade ratios, the chemical composition of electrum and the associated sulfides, the gold(-silver) deposits at Yeongdong District may be classified into 4 classes: pyrrhotite - type gold deposits( I), pyrite - type gold deposits (IT A; massive vein), pyrite - type gold deposits (II B; nonmassive vein) and argentite - type gold - silver deposits(III). The chemical study on electrum(including native gold) revealed that Au content (2.8 to 92.4 atomic%) of electrums varies very widely for different classes of deposits. The Au content of electrum associated with pyrrhotite (Class I), ranging from 47.1 to 92.4 atomic% Au, is clearly higher than that associated with pyrite (Classes IIA, IIB and III). In contrast, classes I, II, and III deposits do not show clear differences in Au content of electrum. In general, pyrrhotite - type gold deposits(I) are characterized by features such as simply massive vein morphology, low values in the Ag/Au total production and ore grade ratios, the absence or rarity of silver - bearing minerals except electrum, and distinctively simple mineralogy. Although the geological and mineralogical features and vein morphology of pyrite - type gold deposits(IIA)are very similar to those of pyrrhotite - type gold deposits (I), Class II A deposits reveal significant differences in the associated iron sulfide (i. e. pyrite) with electrum and Au content of electrum. The Ag/Au total production and ore grade ratios from Class II A deposits are relatively slightly higher than those from Class I deposits. Pyrite - type gold deposits(II B) and argentite - type gold - silver deposits (III) have many common features; complex vein morphology, medium to high values in the Ag/Au total production and ore grade ratios and the associated iron sulfide (i. e. pyrite). In contrast to Class II B deposits, Class III deposits have significantly high Ag/Au total production and ore grade ratios. It indicates distinct difference in the abundance of silver minerals (i. e. native silver and argentite). The fluid inclusion analyses and mineralogical data of electrum tarnish method indicate that the gold mineralization of Classes I and II A deposits was deposited at temperatures between $230^{\circ}$ and $370^{\circ}C$, whereas the gold (-silver) mineralization of Classes ITB and ill formed from the temperature range of $150^{\circ}-290^{\circ}C$. Therefore, Classes I and IT A deposits have been formed at higher temperature condition and/or deeper positions than Classes IIB and III.

  • PDF

Computation method of effective bandwidth of VBR MPEG video traffic using the modified equivalent capacity (수정된 equivalent capcity를 이용한 VBR MPEG 비디오 트랙픽의 등가대역폭 계산방법)

  • 하경봉;이창범;박래홍
    • Journal of the Korean Institute of Telematics and Electronics A
    • /
    • v.33A no.10
    • /
    • pp.40-47
    • /
    • 1996
  • A method for computing effectiv ebandwidth of aggregated varable bit rate (VBR) moving picture experts group (MPEG) video traffic is proposed. To compute statistical characteristics of aggregated MPEG traffic, first we split input MPEG traffic into I, B, and P frame traffics and aggregate respective I, B, and P frame traffics according to the frame type. Second statisticsal characteristics of the aggregated MPEG traffic are obtained using those of aggregated I, B, and P frame traffics. The effective bandwidth of the aggregated I frame traffic is computed by using the gaussian bound. Using the modified equivalent capacity, we obtain the effective bandwidths of aggregated B and P frame traffics and then compute the effective bandwidth of the combined B and P frame traffic. Finally the effective bandwidth of the aggregated MPEG traffic is computed by adding the gaussian bound of the aggregated I frame traffic and modifed equivalent capacity of combined B and P frame traffic. Computer simulation shows that the proposed method estimates effective bandwidth of the aggregated MPEG traffic well.

  • PDF

A Study on Wearing Sensation in Accordance with difference in Materials of Aerobic Wear (에어로빅복의 소재 차이에 따른 착용감에 관한 연구)

  • 이미경;류숙희
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.22 no.1
    • /
    • pp.116-126
    • /
    • 1998
  • This study was conducted to examine the effect of difference in materials of aerobic wear on both human body's physiological reactions and subjective wearing sensation by comparing and analysing not only cotton sparidex A, B and C but nylon spandex D, E and F used as actually wearing materials. The rectal temperature of type A and I remained at high degree, the type C was higher from after high-speed running but dropped sharply when taking a break finally. Both skin temperature and mean skin temperature dropped sharply due to sweat occurred during physical exercise, and then rose slowly when taking a break. Type A -D and B-I showed that the mean skin temperature remained at high degree when wearing a cotton spandex. Type C's temperature within its aerobic wear was lower than type F while its relative humidity was higher than type F. Wearing sensation showed a change similar to wearing, particularly, which was remarkable in type B-E. Also, it was shown that humidity sensation, tactile sensation and comfort sensation were good when wearing the cotton spandex.

  • PDF

Fluid Inclusion Study of the Cretaceous Granite in the Yonghwa Area (용화(龍化)지역에 분포하는 백악기 화강암(化崗岩)에 포함된 유체포유물(流體包有物)에 관한 연구(硏究))

  • Youn, Seok-Tai;Park, Hee-In
    • Economic and Environmental Geology
    • /
    • v.27 no.3
    • /
    • pp.231-236
    • /
    • 1994
  • Fluid inclusions have been studied in phenocryst quartz from the Cretaceous porphyritic granite. Three main types of fluid inclusion were found: liquid-rich inclusion (I type), gas-rich inclusion (II type) and solid-bearing inclusions (III-A, III-B). The solid-bearing inclusions (III-A, B) represent the earliest trapped fluids. They have salinities between 63 and 67.5 wt.% equivalent NaCl. These are high saline inclusions containing NaCl and KCl daughter crystals. Homogenization temperature inferred from the fluid inclusion study ranges from 620 to $700^{\circ}C$. Type I and II inclusions were observed within the same fracture. This cause for these differences in degree of filling is evidence of boiling. Salinities of type I and II inclusions range from 10.24 wt.% to 13.44 wt.%, from 8.4 wt.% to 11.48 wt.% NaCl equivalent, respectively.

  • PDF

A BORSUK-ULAM TYPE THEOREM OVER ITERATED SUSPENSIONS OF REAL PROJECTIVE SPACES

  • Tanaka, Ryuichi
    • Journal of the Korean Mathematical Society
    • /
    • v.49 no.2
    • /
    • pp.251-263
    • /
    • 2012
  • A CW complex B is said to be I-trivial if there does not exist a $\mathbb{Z}_2$-map from $S^{i-1}$ to S(${\alpha}$) for any vector bundle ${\alpha}$ over B a any integer i with i > dim ${\alpha}$. In this paper, we consider the question of determining whether $\Sigma^k\mathbb{R}P^n$ is I-trivial or not, and to this question we give complete answers when k $\neq$ 1, 3, 8 and partial answers when k = 1, 3, 8. A CW complex B is I-trivial if it is "W-trivial", that is, if for every vector bundle over B, all the Stiefel-Whitney classes vanish. We find, as a result, that $\Sigma^k\mathbb{R}P^n$ is a counterexample to the converse of th statement when k = 2, 4 or 8 and n $\geq$ 2k.

The Study on the Long-term Reliability Characteristics by Solar Cell Ribbon Thickness (태양전지 두께에 Ribbon 따른 장기 신뢰성 특성에 관한 연구)

  • Kang, Min-Soo;Jeon, Yu-Jae;Shin, Young-Eui
    • Journal of Energy Engineering
    • /
    • v.22 no.4
    • /
    • pp.333-337
    • /
    • 2013
  • 본 논문에서는 태양전지의 Ribbon 두께(A-type:0.2mm, B-type:0.25mm)에 따라 3가지 온도조건 ($-40{\sim}65^{\circ}C$, $-40{\sim}85^{\circ}C$, $-40{\sim}105^{\circ}C$)으로 열충격 시험을 수행하였다. 그 결과, A, B type 별 초기 평균효율은 15.2%로 같았다. 하지만, 열충격 시험(600 Cycle) 후 Condition 1에서 A-type 7.5%, B-type 7.7%, Condition 2에서는 8.6%, 13.2%를 나타내었다. Condition 3에서는 각각 11.6%, 19.9%의 감소율을 나타내었다. 열충격 시험 후 A-type보다 Ribbon두께가 두꺼운 B-type의 효율이 크게 감소하였다. 이는 A, B type 모두 이종재료 접합부의 금속간화합물(IMC)층이 형성되어 전기적 저항이 증대된 것으로 판단된다. 또한, B-type의 I-V 특성 곡선 및 EL을 분석한 결과, p-n층이 파괴되고, 병렬저항이 감소하여, 장기적 신뢰성에서 A-type 보다 더 취약한 것으로 나타났다. 향후 태양전지 Ribbon 형상에 따른 장기 신뢰성 특성에 대해 수치해석 및 시뮬레이션 분석이 수반되어야 할 것이다.

Performance Characteristics of a Diesel Engine Using the Change of Injection Nozzle Type and Ultrasonic-Energy-Added System(I) (분사노즐 형상 변화와 초음파 에너지 부가장치를 이용한 디젤기관의 성능특성(I))

  • 최두석;류정인
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.5 no.4
    • /
    • pp.160-170
    • /
    • 1997
  • The objective of this study is to investigate the atomization characteristics and the performance characteristics of a C. I. engine by using the changes of the injection nozzle type and the ultrasonic-energy-added system. In order to evaluate the effect of ultrasonic energy and of change of injection nozzle type in the performance characte- ristics of a diesel engine, measurements of droplet size of diesel fuel were carried out by using Malvern system. In all types of injection nozzles, SMD of the ultrasonic- energy -added diesel fuel was smaller than that of the conventional diesel fuel and the more injection pressure increased, the more SMD decreased. There was a small increase in SMD with the distance from injection nozzle under all conditions of the injection nozzle types. The minimum SMD was found in the injection nozzle of B type. In the diesel engine test, there were three results about the engine performance. Compared with the injection nozzle of A type, B type had excellent effects in the engine performance. The most excellent effects about the engine performance were obtained in the case of ultrasonic-energy-added diesel fuel. In addition, the torque diagram in the case of ultrasonic-energy-added diesel fuel was more stable and periodical than others.

  • PDF

Analyzing Optical Water Type Using Digital Visualization (광학적 수형의 디지털 시각화를 이용한 수색분석)

  • Sokjin Choi;Sungil Hwang
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.56 no.6
    • /
    • pp.923-929
    • /
    • 2023
  • This study investigated the optical characterization of water types based on Jerlov's classification, employing the CIE colorimetric system. Digital visualization techniques were applied to articulate watercolor manifestations intuitively. The L* luminance parameter exhibited a discernible reduction from optical water type I III and from type 1 to 9, registering a range between 66 and 84. Analysis of color attributes in each optical water type revealed that in the transition from type I to III, the color a* values spanned from -7.43 to -8.32, while color b* values ranged from -2.97 to -3.33. a* values for optical water types 1 to 9 varied between -6.28 and -10.50, with corresponding b* values ranging from -2.51 to -4.20. Consequently, optical water type I, IA, IB, II, and III were discretely categorized by independent color values, as were optical water types 1, 3, 5, 7, and 9. The digitized representation of watercolor in this inquiry facilitated comprehensive information asso,o;atopm. The study highlights limitations in Jerlov's classification for representing watercolors in different ocean conditions. It emphasized the need to collect color data from various marine areas and formulate a novel color standard or method for comparing colors.

THE OPTIMAL BIVARIATE BONFERRONI-TYPE LOWER BOUNDS

  • Lee, Min-Young
    • Communications of the Korean Mathematical Society
    • /
    • v.14 no.4
    • /
    • pp.789-795
    • /
    • 1999
  • Let $A_1$,A$_2$…, A\ulcorner and B$_1$,B$_2$…, B\ulcorner be two sequences of events on the same probability space. Let X= X\ulcorner(A) and Y-Y\ulcorner)(B), repectively, by the number of those A\ulcorner and B\ulcorner which oc-cur. We establish bivariate lower bounds on the distribution P(X$\geq$1, Y, $\geq$1)and P(X$\geq$i , $Y\geq$j)by linear combinations of the bino-mial moments S\ulcorner, \ulcorner, 1$\leq$i$\leq$j

  • PDF