• Title/Summary/Keyword: Ts-effect

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Difference in Peak and Integrated Target Strengths Depending on Signal Duration Using a Time-Domain Physical Diffraction Theory

  • Lee, Keun-Hwa;Park, Sang-Hyun;Yang, In-Sik;Oh, Won-Tchon;Seong, Woo-Jae
    • The Journal of the Acoustical Society of Korea
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    • v.28 no.3E
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    • pp.88-92
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    • 2009
  • The target strength (TS) is calculated from the measured signal using the definition of the peak TS (PTS) or the integrated TS (ITS). These two types of TS sometimes give different results depending on what the pulse duration is. In this paper, we model the scattered time signal by the numerical code based on the physical diffraction theory and examine the effect of the pulse duration on the value of PTS or ITS. The transformed TS (TTS) for the frequency domain is used as a reference solution.

A study of synthesis method Lean DFSS and Advanced Product Quality Planning of ISO/TS16949 (Lean DFSS와 ISO/TS16949 APQP의 통합에 관한 연구)

  • Kwon, Sok;Lee, Kang-Koon
    • Proceedings of the Korean Society for Quality Management Conference
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    • 2006.11a
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    • pp.381-388
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    • 2006
  • 많은 6시그마 혁신을 하는 기업 중에서 IS09000 시리즈나 IS0/TS16949 인증을 받고 있다. 그럼에도 불구하고 6시그마 도입 초기부터 ISO/TS16949와 통합운영을 생각하고 추진하는 곳은 많지 않다. ISO/TS16949에서는 기업전반의 프로세스에 많은 중점을 두고 있다. 그 중에서도 APQP(Advanced Product Quality Planning)은 제품 초기에서 부터 명확한 품질계획 업무 프로세스를 가지고 활동을 하라는 필수 프로세스를 요구하고 있다. 그러나 구체적인 Flow나 단계는 각 기업체의 특성에 맞기고 있다. 6시그마의 Lean DFSS는 이러한 제품개발 프로세스의 구체적인 전개단계를 제공 하고 있다. 여기에 APQP에 서 요건으로 명시한 각 프로세스 단계마다 인풋(Input)요소, 아웃풋(Output) 요소, 타켓(Target), 그 프로세스를 책임질 구성원, 핵심성공요인(KSF), 핵심성공지수(KPI), 단계마다의 FMEA(Failure Mode Effect Analysis) 분석을 대응하면 도입 초기에서 부터 상호 유기적이면서 효과적인 System이 된다.

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In vitro Anti-inflammation Effect of Adventitious Shoots of Toona sinesis in Propionibacterium acnes-induced Skin Dermatitis

  • Hyeon-Ji Lim;In-Sun Park;Seung-Il Jeong;Kang-Yeol Yu;Chan-Hun Jung
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.12a
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    • pp.73-73
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    • 2020
  • Toona sinensis (TS) leaf is known to antinociceptive, antioxidative stress and skin moisturizing effects. Acnes vulgaris is a chronic skin disease with various symptoms including itchiness, pain and interruption of normal skin function. Propionibacterium acnes (P. acnes) is a major factor in the occurrence of inflammatory acnes. This study evaluated the antioxidant and anti-inflammation effects by TS extract from adventitious shoots. TS extract showed anti-inflammatory activities by suppression of pro-inflammation mediators (iNOS and COX-2) in LPS-stimulated RAW264.7 cells. TS extract also has anti-inflammatory activities by inhibiting the secretion of pro-inflammatory cytokines on P. acnes-stimulated HaCaT cells. These effects were regulated by MAPK signaling pathway. Therefore, we suggest that TS extract from adventitious shoots might have applications as a medicine for treating P. acnes-induced skin diseases.

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Effects of Pretreatment of Alkali-degreasing Solution for Cu Seed Layer (약알칼리탈지 용액에서의 구리 Seed 층의 전처리 효과)

  • Lee, Youn-Seoung;Kim, Sung-Soo;Rha, Sa-Kyun
    • Journal of the Korean Vacuum Society
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    • v.21 no.1
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    • pp.6-11
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    • 2012
  • In order to understand a process of contaminants removal on surface of Cu seed layer (Cu seed/Ti/Si) by sputter deposition, we investigated the changed morphology and states of Cu seed surface after pretreatment in alkali degreasing Metex TS-40A solution according to dipping time. After TS-40A pretreatment, the surface morphology with clearer grains was observed by Field emission scanning electron microscope and the changed surface chemical states and impurities on surface of samples were checked by X-ray photoelectron spectroscopy. Dipping time in TS-40A solution had very little effect on surface of Cu seed layer. After pretreatment, much carbons and little oxygens on surface of Cu seed were eliminated and the decrease of peaks corresponded to O=C and $Cu(OH)_2$ was estimated. However, Si content (=silicate) was detected on sample surface. We think that the silicate impurity forms on Cu seed by chemical reaction of TS-40A solution included silicate component. By pretreatment of alkali degreasing Metex TS-40A solution, it showed an excellent effect in removal of O=C and $Cu(OH)_2$ on Cu seed layer, but the silicate was formed on surface of Cu seed. Therefore, another cleaning process such as acid cleaning is required for removal of this silicate in use of this alkali degreasing.

Seismic Performance of RC Frame System Retrofitted with TS Seismic Strengthening Method (Part 1:Analytical Study) (TS 제진공법으로 내진보강된 철근콘크리트 골조의 내진성능(Part 1:해석적 연구))

  • Jung, Myung-Cheol;Song, Jeong-Weon;Song, Jin-Kyu
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.22 no.2
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    • pp.141-147
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    • 2018
  • In this study, a cyclic loading test was carried out for a reinforced concrete frame installed a TS(tension-spring) damper for the purpose of verifying the seismic strengthening effect of the TS seismic reinforcing method. The test specimens are four specimens of non - reinforced frame and three reinforced frame specimens. Experimental parameters are Shape of damper and construction method of damper. As a result, the construction method of inserting type inside window was twice as much in terms of strength and stiffness, and the method of externally attached type showed a performance improvement of about 2 times in terms of energy dissipation. From these results, it can be confirmed that the TS seismic reinforcing method is a superior method for field application and seismic strengthening.

Effect of CMC-Environment and Interaction-Types on the Achievement and Satisfaction in the Teaching and Learning of Science (CMC 환경과 상호작용 유형이 과학성취도와 만족도에 미치는 효과)

  • Lee, Jeong-Sun;Yoo, Jung-Moon
    • Journal of the Korean earth science society
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    • v.24 no.7
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    • pp.625-634
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    • 2003
  • This study was designed to analyze the differences in science achievement and satisfaction between the environments of Face-To-Face (FTF) and Computer Mediated Communication (CMC), and between the interactions of Teacher-Students (TS) and Students-Students (SS). The activities for the interaction in the FTF and the CMC were carried out in the environments of traditional classrooms and the on-line network of communication computer, respectively. These experiments for four different groups (CMC-TS, CMC-SS, FTF-TS and FTF-SS) were performed with respect to 103 students of three 10th grade classes at a girls' high school in Chungju city. The questionnaires were composed of 5questions for achievement, and 13 questions on Likert scale for satisfaction. The data was analyzed using ANOVA, and through examination of each question about the satisfaction. The mean of the science achievement in learning activity was significantly higher in the CMC environment than the FTF. Also, the score in the TS interaction was meaningfully higher than the SS. Under the common environment of the CMC, science achievement and satisfaction in the TS interaction were significantly higher than in the SS. A similar result has been obtained in the satisfaction case even in the common environment of the FTF. The itemized analysis for the satisfaction shows a high score in the individual condition of CMC and TS, compared to that of FTF and SS, respectively. Thus, the school activity, formed in the TS interaction in the CMC environment is more effective at improving science achievement and satisfaction in the teaching and learning of science.

Predictive V16alue of Thymidylate Synthase Expression in Gastric Cancer: A Systematic Review with Meta-analysis

  • Hu, Hua-Bin;Kuang, Lei;Zeng, Xiao-Min;Li, Bin;Liu, En-Yi;Zhong, Mei-Zuo
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.261-267
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    • 2012
  • Purpose: The relationship between thymidylate synthase (TS) expression and outcomes in gastric cancer (GC) patients remains controversial, although most studies reported poor survival and reduced response to fluoropyrimidine were related to high TS in tumors. We carried out a systematic review of the literature with meta-analysis to estimate the predictive value of TS expression from published studies. Methods: We indentified 24 studies analysing the outcome data in gastric cancer stratified by TS expression. Effect measures of outcome were hazard ratios (HRs) for overall survival (OS) and event-free survival (EFS), or the odds ratio (OR) for overall response rate (ORR). HRs and ORs from these eligible studies were pooled using random-effects meta-analysis. Results: Fifteen studies investigated outcomes in a total of 844 patients with advanced GC, and nine studies investigated outcomes in a total of 1,235 patients with localized GC undergoing adjuvant therapy. Meta-analysis of estimates showed high TS expression was significantly associated with poor OS in the advanced setting (HR: 1.43, 95%CI: 1.08 - 1.90), and poor EFS in the adjuvant setting (HR: 1.53, 95%CI: 1.01 - 2.32). Subgroup analysis demonstrated TS expression to haves even greater value in predicting OS, EFS and ORR in advanced GC patients treated with fluoropyrimidine monotherapy (HR for OS: 2.32, 95%CI: 1.53 - 3.50; HR for EFS: 1.76, 95%CI: 1.19 - 2.60; OR for ORR: 0.32, 95%CI: 0.11 - 0.95). Conclusion: High levels of TS expression were asssociated with a poorer OS for advanced GC patients compared with low levels. In the adjuvant setting, high TS expression was also associated with a worse EFS. Additional studies with consistent methodology are needed to define the precise predictive value of TS.

Electrochemical Properties of Polypyrrole-Glucose Oxidase Enzyme Electrode with Different Dopants (Polypyrrole-Glucose Oxidase 효소전극의 배위자 크기에 따른 전기화학적 특성)

  • 김현철;구할본
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.15 no.2
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    • pp.141-146
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    • 2002
  • We synthesized polypyrrole (PPy) by electrolysis of the pyrrole monomer solution containing support electrolyte, KCl and/or p-toluene sulfonic acid sodium salt (p-TS). The electrochemical behavior, was investigated using cyclic voltammetry and AC impedance. In the case of using electrolyte p-TS, the oxidation potential of the PPy was about -02 V vs Ag/AgCl reference electrode, while the potential was about 0 V for using electrolyte KCl. The falloff of the oxidation potential gave a sign of an improvement in the electron hopoing mechanism on the backbone. The AC impedance plot gave a hint of betterment of mass transport. PPy doped with p-TS improved in mass transport or diffusion. That was because the PPy doped with p-TS was more porous than PPy with KCl. We attained an effect of good kinetic parameters, in the case of PP-GOx enzyme electrodes doped with p-TS, which were determined by 58 mmol dm$\^$-3/ for apparent Michaelis constant and by 581 ㎂ for maximum current respectively.

Anxiolytic Effect of Ginseng Total Saponin (홍삼 사포닌의 항불안 효과)

  • Ryu, Sung-Min;Park, Hyung-Bae;Lee, Jong-Bum;Ha, Jeoung-Hee;Park, Jin-Kyu
    • Korean Journal of Biological Psychiatry
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    • v.4 no.1
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    • pp.102-107
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    • 1997
  • Ginseng root, as a folk medicine, has been used in far eastern countries for thousands of years. Ginseng extract has been shown to have a variety of effects on the activity of the central nervous system, promoting stimulation as well as inhibition of the cortical activity. A survey of the relevant literatures has indicated that the putative anxiolytic activity of red ginseng has not been scientifically investigated. Therefore, the present study was designed to assess anxiolytic effect of gingseng total saponins(GTS). The putative anxiolytic effects of several fractions of GTS were investigated in mice using an elevated plus maze paradigm. Single dose administration of TS Fr.-I showed anxiolytic action in mice. Anxiolytic effect induced by TS Fr.-I was similar to that induced by diazepam. TS Fr.-II, TS Fr.-III and TS Fr.-IV did not show the anxiolytic action compared with that of TS Fr.-I. It was suggested that regulation of GABAergic neurotransmission may be important in the action of GTS. The Interaction of GTS fractions with benzodiazepine receptor was performed using rat cortical membranes. GTS inhibited the binding of [3H] Ro 15-1788 on the benzodiazepine receptor. Among from TS fractions, the binding activity of GTS in the TS Fr.-IV was highest, which did not show the anxiolytic activity. From these results, we conclude that GTS has anxiolytic action, and this is not related to benzodiazepine receptor binding activity.

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OVERCOMING THE NUTRITIONAL LIMITATIONS OF RICE STRAW FOR RUMINANTS 1. UREA AMMONIA TREATMENT AND SUPPLEMENTATION WITH RICE BRAN AND GLIRICIDIA FOR LACTATING SURTI BUFFALOES

  • van der Hoek, R.;Muttetuwegama, G.S.;Schiere, J.B.
    • Asian-Australasian Journal of Animal Sciences
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    • v.1 no.4
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    • pp.201-208
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    • 1988
  • Fifty-six lactating Surti buffaloes, fed rice straw, were allocated to seven treatment groups as follows: 1. Straw supplemented with 2% urea (SS) + 1.5kg rice bran (RB) 2. Straw treated with 4% urea in an open stack (TS open) 3. TS open + 1.5 kg RB 4. TS open + 3.0 kg RB 5. TS open + 1.5 kg RB + 3.0 kg Gliricidia (Gl) 6. Straw treated with 4% urea in a closed pit (TS closed) 7. TS closed + 1.5 kg RB + 3.0 kg Gl Milk production, butterfat percentage and liveweight gain of cows and calves were measured and tested with analysis of variance. The results are: - The animals on urea treated straw (group 2) had a higher milk production (p<0.05), higher butterfat production (p<0.05) and less liveweight gain loss (p<0.05) than the animals on urea supplemented straw (group 1). Butterfat percentage also increased by treatment, although not significantly (p>0.05). - Increasing levels of rice bran (groups 3 and 4 compared to 2) increased total milk production and milked quantity of butterfat, while butterfat percentage decreased (p < 0.05). - Milk production increased (p <0.05) with extra rice bran added (group 4 compared to 3), but was not affected (p > 0.05) by Gliricidia addition (group 5 compared to 3). Butterfat percentage dropped with extra rice bran supplement (p <0.05). The lack of response to Gliricidia indicated that protein is not limiting in treated straw, or that Gliricidia protein is partly insoluble. - System of treatment had no effect on milk production (p >0.05), while supplementation with 1.5 kg RB and 3.0 kg Gliricidia increased production and caused a lower butterfat percentage (p <0.05) (groups 2, 5, 6 and 7 compared). A significant (p <0.05) interaction treatment system x supplementation was present. It was concluded, that both treatment and supplementation did affect milk production as well as milk composition. Gliricidia addition gave less effect than rice bran, indicating different requirements for starchy substances in the feed. Treatment of straw does not negatively affect butterfat production, it can increase butterfat production and even butterfat percentage.