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Validation of MoCA-MMSE Conversion Scales in Korean Patients with Cognitive Impairments

  • Jung, Young Ik;Jeong, Eun Hye;Lee, Heejin;Seo, Junghee;Yu, Hyun-Jeong;Hong, Jin Y.;Sunwoo, Mun Kyung
    • Dementia and Neurocognitive Disorders
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    • v.17 no.4
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    • pp.148-155
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    • 2018
  • Background and Purpose: Two conversion scales between the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) have been validated for Korean patients with Parkinson's disease. The aim of the present study was to validate these conversion scales for all patients with cognitive impairments regardless of dementia subtype. Methods: Medical records of 323 subjects who completed both MMSE and MoCA on the same day were retrospectively reviewed. Mean, median, and root mean squared error (RMSE) of the difference between true and equivalent MMSE scores were calculated. Intraclass correlation coefficients (ICCs) between true and equivalent MMSE scores were also calculated. The validity of MoCA-MMSE conversion scales was evaluated according to educational level (low educated: ${\leq}6$ years; high educated: ${\geq}7$ years) and subtypes of cognitive impairment. Results: The difference between true and equivalent MMSE scores had a median value of 0, a mean value of 0.19 according to the van Steenoven scale, a mean value of 0.57 according to the Lawton scale, RMSE value of 2.2 according to the van Steenoven scale, and RMSE value of 0.42 according to the Lawton scale. Additionally, ICCs between true and equivalent MMSE scores were 0.92 and 0.90 on van Steenovan and Lawton conversion scales, respectively. These results were maintained in subgroup analyses. Conclusions: Findings of the present study suggest that both van Steenovan and Lawton MoCA-MMSE conversion scales are applicable to transforming MoCA scores into MMSE scores in patients with cognitive impairments regardless of dementia subtype or educational level.

Contemporary Society and the Meaning of Korean Traditional Thoughts (현대사회와 한국 전통사상의 의의 - 근현대 인문학 사회과학에 대한 진단을 중심으로 -)

  • Lee, Sang-Ik
    • The Journal of Korean Philosophical History
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    • no.58
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    • pp.65-96
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    • 2018
  • Modern and contemporary humanities and social sciences supported the freedom and abundance of people. Today, however, freedom and abundance do not support human dignity, and are not sustainable. Therefore, we must reflect again on the direction of today's life and civilization. As part of this project, this essay analyzes the modern and contemporary humanities and social sciences and examines the meaning of Korean traditional thoughts. The lines presented to us by Korean traditional thought can be summed up 'the Three Elements of the Universe(Heaven, Earth and Man)' and 'Perfect Harmony between the Soul and the Body' and 'true humanitarianism.' These lines can be a starting point to overcome the problems posed by the lines of freedom and abundance in two contexts : First, while the lines of freedom and abundance today were biased toward the elements of the Earth or the Body, the traditional Korean thoughts have been both elements of the Heaven and the Soul since the beginning, which can therefore serve as a true humanitarian. Second, the true humanitarian line is as much sustainable as it criticizes the uncontrolled freedom and abundance, and seeks the right moderation to become a man of dignity.

Muscle Functional MRI of Exercise-Induced Rotator Cuff Muscles

  • Tawara, Noriyuki;Nishiyama, Atsushi
    • Investigative Magnetic Resonance Imaging
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    • v.25 no.1
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    • pp.1-9
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    • 2021
  • The aim of this study was to provide a new assessment of rotator cuff muscle activity. Eight male subjects (24.7 ± 3.2 years old,171.2 ± 9.8 cm tall, and weighing 63.8 ± 11.9 kg) performed the study exercises. The subjects performed 10 sets of the exercise while fixing the elbow at 90 degrees flexure and lying supine on a bed. One exercise set consisted of the subject performing external shoulder rotation 50 times using training equipment. Two imaging protocols were employed: (a) true fast imaging with steady precession (TrueFISP) at an acquisition time of 12 seconds and (b) multi-shot spin-echo echo-planar imaging (MSSE-EPI) at an acquisition time of 30 seconds for one echo. The main method of assessing rotator cuff muscle activity was functional T2 mapping using ultrafast imaging (fast-acquired muscle functional MRI [fast-mfMRI]). Fast-mfMRI enabled real-time imaging for the identification and evaluation of the degree of muscle activity induced by the exercise. Regions of interest were set at several places in the musculus subscapularis (sub), musculus supraspinatus (sup), musculus teres minor (ter), and deltoid muscle (del). We used the MR signal of the images and transverse relaxation time (T2) for comparison. Most of the TrueFISP signal was not changed by exercise and there was no significant difference from the resting values. Only the T2 in the musculus teres minor was increased after one set and the change were seen on the T2 images. Additionally, except for those after one and two sets, the changes in T2 were significant compared to those at rest (P < 0.01). We also demonstrated identify and visualize the extent to which muscles involved in muscle activity by exercise. In addition, we showed that muscle activity in a region such as a shoulder, which is susceptible to B0 inhomogeneity, could be easily detected using this technique.

Comparison of Vitamin B5 Content and True Retention in Commonly Consumed Vegetables by Different Cooking Methods (국내 다소비 채소류의 조리에 따른 비타민 B5 함량 및 잔존율 비교)

  • Jin Ju, Park;Arin, Park;Eunji, Park;Youngmin, Choi
    • Journal of the Korean Society of Food Culture
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    • v.37 no.6
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    • pp.540-546
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    • 2022
  • This study aimed to determine the changes in the vitamin B5 content of raw and cooked vegetables. The nineteen vegetables were subjected to different cooking methods, viz. blanching, boiling, pan-broiling, and steaming. Vitamin B5 was quantified by reversed-phase high-performance liquid chromatography (HPLC) using photodiode-array (PDA) detection (200 nm). The standard reference materials (SRM) were used to validate the accuracy of vitamin B5 measurement method used in this study. The cooking yields ranged from 82.63 to 107.62% and decreased in most of the vegetables except bitter melon, curled mallow, and eggplant. The raw kabocha squash, Danhobak, had the highest vitamin B5 content (0.671 mg/100 g) among the samples. All cooked vegetables showed lower vitamin B5 content compared to the raw samples. The true retention ranged from 0% (crown daisy, blanching) to 84.49% (kabocha squash, steaming). These results indicate that vitamin B5 is degraded after cooking. Pan-broiling and steaming are better cooking methods than the others for retaining vitamin B5. The true retention of vitamin B5 in the samples markedly depends on the cooking method and food matrix. These results can be used as important basic data for nutritional evaluation of meals.

A Study of 0.5-bit Resolution for True-Time Delay of Phased-Array Antenna System

  • Cha, Junwoo;Park, Youngcheol
    • International journal of advanced smart convergence
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    • v.11 no.4
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    • pp.96-103
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    • 2022
  • This paper presents the analysis of increasing the resolution of True-Time-Delay (TTD) by 0.5-bit for phased-array antenna system which is one of the Multiple-Input and Multiple Output (MIMO) technologies. For the analysis, a 5.5-bit True-Time Delay (TTD) integrated circuit is designed and analyzed in terms of beam steering performance. In order to increase the number of effective bits, the designed 5.5-bit TTD uses Single Pole Triple Throw (SP3T) and Double Pole Triple Throw (DP3T) switches, and this method can minimize the circuit area by inserting the minimum time delay of 0.5-bit. Furthermore, the circuit mostly maintains the performance of the circuit with the fully added bits. The idea of adding 0.5-bit is verified by analyzing the relation between the number of bits and array elements. The 5.5-bit TTD is designed using 0.18 ㎛ RF CMOS process and the estimated size of the designed circuit excluding the pad is 0.57×1.53 mm2. In contrast to the conventional phase shifter which has distortion of scanning angle known as beam squint phenomenon, the proposed TTD circuit has constant time delays for all states across a wide frequency range of 4 - 20 GHz with minimized power consumption. The minimum time delay is designed to have 1.1 ps and 2.2 ps for the 0.5-bit option and the normal 1-bit option, respectively. A simulation for beam patterns where the 10 phased-array antenna is assumed at 10 GHz confirms that the 0.5-bit concept suppresses the pointing error and the relative power error by up to 1.5 degrees and 80 mW, respectively, compared to the conventional 5-bit TTD circuit.

True Digestibility of Phosphorus in Different Resources of Feed Ingredients in Growing Pigs

  • Wu, X.;Ruan, Z.;Zhang, Y.G.;Hou, Y.Q.;Yin, Y.L.;Li, T.J.;Huang, R.L.;Chu, W.Y.;Kong, X.F.;Gao, B.;Chen, L.X.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.1
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    • pp.107-119
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    • 2008
  • To determine the true digestible phosphorus (TDP) requirement of growing pigs, two experiments were designed with the experimental diets containing five true digestible P levels (0.16%, 0.20%, 0.23%, 0.26% and 0.39%) and the ratio of total calcium to true digestible P (TDP) kept at 2:1. In Experiment 1, five barrows (Duroc${\times}$Landrace${\times}$Yorkshire) with an average initial body weight of 27.9 kg were used in a $5{\times}5$ Latin-square design to evaluate the effect of different dietary P levels on the digestibility and output of P and nitrogen. In Experiment 2, sixty healthy growing pigs (Duroc${\times}$Landrace${\times}$Yorkshire) with an average body weight (BW) of 21.4 kg were assigned randomly to one of the five dietary treatments (12 pigs/diet), and were used to determine the true digestible phosphorus (TDP) requirement of growing pigs on the basis of growth performance and serum biochemical indices. The results indicated that the true digestibility of P increased (p<0.05) linearly with increasing dietary TDP level below 0.26%. The true P digestibility was highest (56.6%) when dietary TDP was 0.34%. Expressed as g/kg dry matter intake (DMI), fecal P output increased (p<0.05) linearly with increasing P input. On the basis of g/kg fecal dry matter (DM), fecal P output was lowest for Diet 4 and highest (p<0.05) for Diet 5. The apparent digestibility of crude protein (CP) did not differ (p>0.05) among the five diets, with the average nitrogen output of 12.14 g/d and nitrogen retention of 66% to 74% (p>0.05), which suggested that there was no interaction between dietary P and CP protein levels. During the 28-d experimental period of Experiment 2, the average daily gain (ADG) of pigs was affected by dietary TDP levels as described by Eq. (1): $y=-809,532x^4+788,079x^3-276,250x^2+42,114x-1,759$; ($R^2=0.99$; p<0.01; y = ADG, g/d; x = dietary TDP, %), F/G for pigs by Eq. (2): $y=3,651.1x^4-3,480.4x^3+1,183.8x^2-172.5x+10.9$ ($R^2=0.99$; p<0.01; y = F/G; x = dietary TDP, %), and Total P concentrations in serum by Eq. (3): $y=-3,311.7x^4+3,342.7x^3-1,224.6x^2+195.6x-8.7$ (R2 = 0.99; p<0.01; y = total serum P concentration and x = dietary TDP, %). The highest ADG (782 g/d), the lowest F/G (1.07) and the highest total serum P concentration (3.1 mmol/L) were obtained when dietary TDP level was 0.34%. Collectively, these results indicate that the optimal TDP requirement of growing pigs is 0.34% of the diet at a total Ca to TDP ratio of 2:1.

Evaluation of surface dose comparison by treatment equipment (치료 장비 별 표면 선량 비교평가)

  • Choi Eun Ha;Yoon Bo Reum;Park Byoung Suk;An Ye Chan;Park Myoung Hwan;Park Yong Chul
    • The Journal of Korean Society for Radiation Therapy
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    • v.34
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    • pp.31-42
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    • 2022
  • Purpose: This study measures and compares the surface dose values in the virtual target volume using Tomotherapy, Halcyon, and TrueBeam equipment using 6MV-Flattening Filter-Free(FFF) energy. Materials and Methods: CT scan was performed under three conditions of without bolus, 0.5 cm bolus, and 1 cm bolus using an IMRT phantom (IBA, Germany). The Planning Target Volume (PTV) was set at the virtual target depth, and the treatment plan was established at 200 cGy at a time. For surface dosimetry, the Gafchromic EBT3 film was placed in the same section as the treatment planning system and repeated measurements were performed 10 times and then analyzed. Result: As a result of measuring the surface dose for each equipment, without, 0.5 cm, 1 cm bolus is in this order, and the result of Tomotherapy is 115.2±2.0 cGy, 194.4±3.3 cGy, 200.7±2.9 cGy, The result in Halcyon was 104.7±3.0 cGy, 180.1±10.8 cGy, 187.0±10.1 cGy, and the result in TrueBeam was 92.4±3.2 cGy, 148.6±5.7 cGy, 155.8±6.1 cGy, In all three conditions, the same as the treatment planning system, Tomotherapy, Halcyon, TreuBeam was measured highly in that order. Conclusion: Higher surface doses were measured in Tomotherapy and Halcyon compared to TrueBeam equipment. If the characteristics of each equipment are considered according to the treatment site and treatment purpose, it is expected that the treatment efficiency of the patient will increase as well as the treatment satisfaction of the patient.

Determination of a critical damage by experiment and analysis of tensile test (인장시험의 실험과 해석 결과를 이용한 임계손상도의 결정)

  • Jang, S.M.;Eom, J.G.;Lee, M.C.;Joun, M.S.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2008.10a
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    • pp.292-296
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    • 2008
  • A new method of evaluating critical damage values of commercial materials is presented in this paper. The method is based on the previous study of the methodology [1] of acquisition of true stress-strain curves or flow stress curves over large strain from the tensile test in which the flow stress is described by the Hollomon law-like form, that is, by the strain dependent strength coefficient and the strain hardening exponent. The strain hardening exponent is calculated from the true strain at the necking point to meet the Considere condition. The strength coefficient is assumed to be constant before necking and represented by a piecewise linear function of strain after necking. With the predicted flow stress, a tensile test is simulated by a rigid-plastic finite element method with higher accuracy of less than 0.5% error between experiments and predictions. The instant when the fracture begins and thus the critical damage is obtained is determined by observing the stress variation at the necked region. It is assumed that the fracture due to damage begins when the pattern of stress around the necked region changes radically. The method is applied to evaluate the critical damage of a low carbon steel.

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Illness Experience of Women with Breast cancer in Korea: Using Feminist Phenomenology (페미니스트 현상학을 이용한 한국 유방암 환자의 질병체험)

  • Park, Eun-Young;Yi, Myung-Sun
    • Korean Journal of Adult Nursing
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    • v.21 no.5
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    • pp.504-518
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    • 2009
  • Purpose: The purpose is to explore the illness experience of Korean women with breast cancer using feminist phenomenology. Methods: Data were collected by individual in-depth interviews from ten women with total mastectomy. The data were analyzed using Colaizzi's method from feminist perspective to reveal implicit socio-cultural norms that oppress women with breast cancer. Results: Two categories and seven major themes emerged: cancer-related experience (1) unfairness of having breast cancer; (2) being confined to the gaze of the others; patriarchy-related experience (3) hardness of being daughter-in-law; (4) struggling to keep on being good mother; (5) continued housework as duty; (6) recognizing self as precious wife, and (7) awakening of true self. All participants felt it was very unfair to get breast cancer because they had done their best for roles of mother, wife, and daughter-in-law. They struggled to free themselves from the social disgrace like the roles imposed by the patriarchal society. By awakening their true selves, they could manage a balance between other-oriented life and self-oriented life. Conclusion: Oncology nurses need to provide psychosocial support for women with breast cancer in finding their true selves in a traditional patriarchal society where women are oppressed and breast cancer is stigmatized.

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EFFECT OF HEAT TREATMENT ON NUTRITIONAL VALUE OF WINGED BEAN (Psophocarpus tetragonolobus) AS COMPARED TO SOYBEAN II. AMINO ACIDS DIGESTIBILITY

  • Mutia, R.;Uchida, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.7 no.1
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    • pp.113-117
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    • 1994
  • The effect if heat treatment (autoclave) in amino acid digestibility of winged bean determined using intact cockerels had been investigated. The winged beans were autoclaved at $120^{\circ}C$ for 45 or 90 min, respectively, and the soybean were autoclaved for 45 min. The treated winged bean and soybean were fed to 3 intact cockerels, which had been previously starved for 24 h. Excreta were collected individually for 49 h. The amino acids contained in the diets and excreta were determined to measure the digestibility values. Apparent and true digestibilities of all amino acids except histidine of unheated winged bean were significantly (P < 0.05) lower than those of heated winged bean and soybean. Heat treatment significantly (p < 0.05) improved amino acid digestibility of winged bean, However, over heating (90 min if autoclaving) destroyed lysine, cystine and arginine of winged bean. The true digestibility values of all amino acids of winged bean heated for 90min were the same as those values of treated soybean. However, true digestibilities of glycine, alannine, phenylalanine and lysine of treated soybean were significantly (p < 0.05) higher than those of winged bean heated for 45 min.