• Journal of IKEEE
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• v.28 no.1
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• pp.72-77
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• 2024

In this paper, a triple-mode frequency-tunable filter is proposed to meet the recent demands of various frequency bands of mobile communication services. This filter has a tunable structure that can adjust the resonance frequency using a variable capacitor. To improve the quality factor, a SIW(Substrate Integrated Waveguide) structure was introduced and a structure that induces three resonance modes was implemented through a circular hole located in the center. The change in electric field distribution and resonance frequency by the variable capacitor was simulated using HFSS, and the change in electric field distribution and resonance frequency of Triple Mode mode was confirmed.

• Journal of the Korean Magnetic Resonance Society
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• v.14 no.2
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• pp.117-126
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• 2010

Hsp33 is a molecular chaperone achieving a holdase activity upon response to a dual stress by heat and oxidation. Despite several crystal structures available, the activation process is not clearly understood, because the structure inactive Hsp33 as its reduced, zinc-bound, monomeric form has not been solved yet. Thus, we initiated structural investigation of the reduced Hsp33 monomer by NMR. In this study, to overcome the high molecular weight (33 kDa), the protein was triply isotope-[$^{13}C$, $^{15}N$, $^2H$]-labeled and its inactive, monomeric state was ensured. 2D-[$^1H$, $^{15}N$]-TROSY and a series of triple resonance spectra could be successfully obtained on a high-field (900 MHz) NMR machine with a cryoprobe. However, under all of the different conditions tested, the number of resonances observed was significantly less than that expected from the amino acid sequence. Thus, a possible contribution of dynamic conformational exchange leading to a line broadening is suggested that might be important for activation process of Hsp33.

• Journal of the Korean Magnetic Resonance Society
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• v.19 no.2
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• pp.83-87
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• 2015

Syndesmos, which is co-localized with syndecan-4 cytoplasmic domain ($Syn4^{cyto}$) in focal contacts, interacts with various cell adhesion adaptor proteins including $Syn4^{cyto}$ to control cell signaling. Syndesmos consists of 211 amino acids and it exists as a dimer (44kDa) in solution. Recently, we have determined the structure of syndesmos by x-ray crystallography, however, dynamics related to syndecan binding still remain elusive. In this report, we performed NMR experiments to acquire biochemical and structural information of syndesmos. Based on a series of three-dimensional triple resonance experiments on a $^{13}C/^{15}N/^2H$ labeled protein, NMR spectra were obtained with well dispersed and homogeneous NMR data. We present the sequence specific backbone assignment of syndesmos and assigned NMR data with combination structural information can be directly used for the studies on interaction with $Syn4^{cyto}$ and other binding molecules.

• Journal of electromagnetic engineering and science
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• v.12 no.2
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• pp.185-188
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• 2012

A compact monopole antenna possessing triple resonance ($f_1$, $f_2$, $f_3$) characteristics for (USB) dongle applications is presented. The resonance characteristic $f_1$ is determined by the overall length of the antenna. The monopole antenna acts as the main radiator for $f_3$ as well as the coupling feeding structure for the parasitic resonators in $f_1$, $f_2$. The resonance characteristic $f_2$ is achieved by a combination of the capacitance formed by the coupling between the top and bottom parasitic substrate resonators and the inductance generated by a via bridging the two parasitic resonators.

• Journal of the Korean Magnetic Resonance Society
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• v.10 no.2
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• pp.175-187
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• 2006

Binding interactions between a positively charged porphyrin derivative TMAP(meso-tetra(p-trimethylanilinium-4-yl)porphyrin) and triple helical $(dT)_{12}{\cdot}(dA)_{12}{\cdot}(dT)_{12}$, as well as double helical $(dA)_{12}{\cdot}(dT)_{12}$ have been studied with NMR, UV and CD spectroscopy to obtain the detailed information about the binding mode and binding site. UV melting studies showed both DNA duplex and triple helix represented very similar UV absorption patterns upon binding TMAP, but the presence of third strand of triple helical $(dT)_{12}{\cdot}(dA)_{12}{\cdot}(dT)_{12}$, inhibited improvement in thermal stability in terms of melting temperature, $T_m$. In addition, the TMAP molecule is thought to bind to the major groove, according to CD and NMR data. But absence of the clear isosbestic point in UV absorption spectra represented that binding of TMAP to DNA duplex as well as DNA triplex did not show a single binding mode, rather complex binding modes.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.5 s.347
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• pp.156-161
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• 2006

In this paper, GPS/IMT2000/Wireless LAN compact chip antenna is designed for mobile communication system. The proposed antenna size is $10.2mm{\times}21mm{\times}1mm$. It consists of three meander lines. dual resonance frequencies is achieved by two effective current paths using two meander lines and via. also The parasitic meander line structure is added. The coupling is adjusted by arranging parasitic meander line for triple-band. The fabricated antenna achieve triple-band. The resonance frequencies are 1.672GHz, 2.092GHz, 2.504GHz. The impedance bandwidths of each resonance frequencies are 156MHz, 272MHz, 64MHz. The maximum radiation gains of fabricated antenna are 0.08dBi, 1.67dBi, -1.44dBi. The proposed antenna achieve quasi monopole radiation pattern.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.20 no.8
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• pp.746-752
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• 2009

In this paper, we deal with the development of an optimal design program for a triple-band PTFA(Planar Inverted-F Antenna) of 433 MHz, 912 MHz and 2.45 GHz by using evolution strategy. Generally, the resonance frequency of the PIFA is determined by the width and length of a U-type slot used. However the resonance frequencies of the multiple U slots are varied by the mutual effect of the slots. Thus the optimal width and length of U-type slots are determined by using an optimal design program based on the evolution strategy. To achieve this, an interface program between a commercial EM analysis tool and the optimal design program is constructed for implementing the evolution strategy technique that seeks a global optimum of the objective function through the iterative design process consisting of variation and reproduction. The resonance frequencies of the triple-band PIFA yielded by the optimal design program are 430 MHz, 910.5 MHz and 2.458 GHz that show a good agreement to the design target values.

• Journal of electromagnetic engineering and science
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• v.12 no.3
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• pp.210-215
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• 2012

This paper presents a compact microstrip triple-mode filter with enhanced skirt characteristics. The presented triple-mode filter configuration supports three transmission poles and three transmission zeros within the nearby passband. Two of transmission zeros are generated by a triple-mode resonator itself, and the third one is generated by small cross-couplings between the I/O ports. Each resonance condition and the transmission zero generation conditions are analyzed using an equivalent circuit. The bandpass filter is designed for a 2.4 GHz WLAN. The filter was fabricated with a relative dielectic constant of 3.5 and a thickness of 0.76 mm. The fabricated filter has a small size ($7.9mm{\times}7.2mm$, i.e., $0.107{\lambda}_g{\times}0.098{\lambda}_g$, where ${\lambda}_g$ is guided wavelength at a center frequency) and shows high performing skirt characteristics.

• Investigative Magnetic Resonance Imaging
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• v.14 no.2
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• pp.95-102
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• 2010

Purpose : To evaluate the magnetic resonance imaging (MRI) and clinicopathological features of triple negative breast cancer, and compare them with those of non-triple negative breast cancer. Materials and Methods : This study included 231 pathologically confirmed breast cancers from January 2007 to May 2008. We retrospectively reviewed the MRI findings according to the Breast Imaging Reporting and Data System (BI-RADS) lexicon: mass or non-mass type, mass shape, mass margin, non-mass distribution, and enhancement pattern. Histologic type, histologic grade, and the results for epidermal growth factor receptor, p53, and Ki 67 were reviewed. Results : Of 231 patients, 43(18.6%) were triple negative breast cancer. Forty triple negative breast cancers (93.0%) were mass-type lesion on MRI. A round or oval or lobular shape (p=0.006) and rim enhancement (p=0.004) were significantly more in triple negative breast cancer than non- triple negative breast cancer. In contrast, irregular shape (p=0.006) and spiculated margins (p=0.032) were significantly more in non-triple negative breast cancer. Old age (p=0.019), high histologic grade (p<0.0001), EGFR positivity (p<0.0001), p53 overexpression (p=0.038), and Ki 67 expression (<0.0001) were significantly associated with the triple negative breast cancer. Conclusion : MRI finding may be helpful for differentiation between triple negative and non-triple negative breast cancer.

• Journal of the Korean Magnetic Resonance Society
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• v.19 no.3
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• pp.112-118
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• 2015

Hsp31 protein is one of the members of DJ-1 superfamily proteins and has a dimeric structure of which molecular weight (MW) is 62 kDa. The mutation of DJ-1 is closely related to early onset of Parkinson's disease. Hsp31 displays $Zn^{+2}$-binding activity and was first reported to be a holding chaperone in E. coli. Its additional glyoxalase III active has recently been characterized. Moreover, an incubation at $60^{\circ}C$ induces Hsp31 protein to form a high MW oligomer (HMW) in vitro, which accomplishes an elevated holding chaperone activity. The NMR technique is elegant method to probe any local or global structural change of a protein in responses to environmental stresses (heat, pH, and metal). Although the presence of the backbone chemical shifts (bbCSs) is a prerequisite for detailed NMR analyses of the structural changes, general HSQC-based triple resonance experiments could not be used for 62 kDa Hsp31 protein. Here, we prepared the per-deuterated Hsp31 and performed the TROSY-based triple resonance experiments for the bbCSs assignment. Here, detailed processes of per-deuteration and the NMR experiments are described for other similar NMR approaches.