• Title/Summary/Keyword: Trials

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Design of Sensitivity-Maximizing Input for Submersibles' Manoeuvring Coefficients using Genetic Algorithm Technique (유전 알고리즘을 이용한 수중운동체 조종성미계수의 민감도 최대화 입력 설계)

  • Yeo, Dong-Jin;Rhee, Key-Pyo
    • Journal of the Society of Naval Architects of Korea
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    • 제43권2호
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    • pp.156-163
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    • 2006
  • The accuracy of estimates of hydrodynamic coefficients can be increased by using sensitivity-maximizing inputs. In this study, sensitivity-maximizing actuator commands of a submersible, which are sequences of bang-bang type commands, were obtained using Genetic Algorithm (GA) optimization technique. By comparing the total sensitivity values, deduced actuator inputs were found to be superior to the other sea trials. Based on the sensitivity distribution of conventional sea trials and sensitivity distribution results through deduced input scenario a review of submersibles' manoeuvring equations of motion was conducted .

Two Bayesian methods for sample size determination in clinical trials

  • Kwak, Sang-Gyu;Kim, Dal-Ho;Shin, Im-Hee;Kim, Ho-Gak;Kim, Sang-Gyung
    • Journal of the Korean Data and Information Science Society
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    • 제21권6호
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    • pp.1343-1351
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    • 2010
  • Sample size determination is very important part in clinical trials because it influences the time and the cost of the experimental studies. In this article, we consider the Bayesian methods for sample size determination based on hypothesis testing. Specifically we compare the usual Bayesian method using Bayes factor with the decision theoretic method using Bayesian reference criterion in mean difference problem for the normal case with known variances. We illustrate two procedures numerically as well as graphically.

Chuna Manual Therapy for Primary Insomnia; A Review of Clinical Study (일차성 불면증의 추나 치료에 대한 문헌 연구 보고)

  • Hwang, Man-Suk
    • Journal of Korean Medicine Rehabilitation
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    • 제26권3호
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    • pp.79-84
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    • 2016
  • Objectives To evaluate the evidence supporting the effectiveness of Chuna manual therapy for primary insomnia. Methods The researcher conducted search across the 3 electronic databases (Pubmed, CAJ and Oasis) to find all of randomized controlled clinical trials(RCTs) that used Chuna manual therapy as a treatment for primary insomnia. Results Four RCTs met inclusion criteria. The meta-analysis showed positive results for the use of Chuna manual therapy in terms of the PSQI when compared to medication treatments alone. Positive results were also obtained, in terms of the PSQI, when comparing Chuna manual therapy combined with acupuncture therapy to acupuncture therapy alone, but was not statistically significant. Conclusions The review found encouraging but limited evidence of Chuna manual therapy for primary insomnia. We recommend clinical trials which compare the effectiveness of Chuna manual therapy with usual care to obtain stronger evidence without the demerits of trial design.

Removal of Total Suspended Solids by a Foam Fractionator in a Simulated Seawater Aquaculture System

  • Peng, Lei;Jo, Jae-Yoon
    • Journal of Aquaculture
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    • 제16권4호
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    • pp.216-222
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    • 2003
  • In a simulated seawater aquaculture system, effects of different operating factors like the superficial air velocity (SAY), hydraulic residence time (HRT), protein concentration and foam overflow height on the removal of total suspended solids (TSS) by a foam fractionator, with 20 cm diameter and 120 cm height, were investigated. This experiment was performed on batch and consecutive modes for different combinations of the tested factors, using synthetic wastewater. In 5 consecutive trials, TSS concentration in culture tank water decreased faster, when the foam fractionator was operated at higher SAV and lower HRT. In batch trials, with increasing SAV, TSS removal rate increased, but decreased with increasing HRT. Higher protein concentration in the bulk solution resulted in higher TSS removal rate. TSS concentration in the collected foam condensates increased but the foam overflow rate decreased with increasing foam overflow height. Foam fractionation was effective for removing TSS in seawater aquaculture systems and its performance largely depended on the operating parameters, especially superficial air velocity.

Recent Advances in Idiopathic Pulmonary Fibrosis

  • Park, Sanghoon;Lee, Eun Joo
    • Tuberculosis and Respiratory Diseases
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    • 제74권1호
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    • pp.1-6
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    • 2013
  • The concept on idiopathic pulmonary fibrosis (IPF) pathogenesis has progressed from chronic inflammation to aberrant wounding healing and even more to the current paradigms of a multifactorial and heterogeneous disease process. Despite the growth of clinical trials for IPF, most of the results, including N-acetylcysteine combination, warfarin, and bosentan, were disappointing. On the other hand, there have been a number of important developments; the foremost is the licensing of pirfenidone in Europe and Asia. In this article, we briefly review the recent knowledge of pathogenesis of IPF. We also summarize the recent clinical trials regarding the management of IPF.

Study on the control of Early Elight of Potato of Potato with Several New Fungicides (감자$\cdot$겹 둥근 무늬병에 대한 신살균제 효과 비교 시험)

  • Jung Bong Jo;Lee Soon Hyong
    • Korean journal of applied entomology
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    • 제2권
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    • pp.12-15
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    • 1963
  • 1. The trials were planned to test seven different fungicides for the control of Early blight of potato during the period of 1962 and 1963. 2. All of fungicides tested in the trials were considerably effective to control the disease, as the result of 4 applications which was done in one week intervals from early of June in 1963. All treatments were effective enough to make significant differences from the untreated. Especially, Dithyane M45, Difolatan and Dithane M22 showed satisfactory control even though no significant differences were obtained among them. Besides the three treatments, Bordeaux Mixture were relatively effective.

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Breeding Process and Characteristics of KG101, a Superior Line of Panax ginseng C.A. Meyer (인삼 우수계통 KG101의 육성경과 및 생육특성)

  • 권우생;정찬문
    • Journal of Ginseng Research
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    • 제22권1호
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    • pp.11-17
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    • 1998
  • To develop a new ginseng varieties with good quality and high yielding, a lot of individual ginseng plants were selected in the farmer's fields in 1972. Among them, a promising line, 7259-3-1, has been developed through comparative cultivation of several lines selected with pure line separation of local races in Korea Ginseng '||'&'||' Tobacco Research Institute. Preliminary and advanced yield trials were performed for 8 years. It was then designated as "KG 101" and tested in the regional yield and adaptation trials for 10 years (1981-1990). KG101 has a green stem with light violet and orange-yellow fruit and flowers 3-7 days later than local race, Takyungjong. Taproot of KG101 was longer than local race Jakyungjong, and root yield of KG101 was 9% higher than local race Jakyungjong. In red ginseng quality, the rates of Chun-Jeesam (Chun and Jee means 1st and 2nd grade, respectively) were 22.3% and 9.4% for KG101 and Jakyungjong, respectively. In these results, it was clarified that KG101 was superior ginseng line with good quality.y.

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Effects of the Provision of Information on Anxiety in Patients during Outpatient Surgery: A Systematic Review (정보제공이 외래 의식 하 수술, 시술 환자의 불안에 미치는 영향: 체계적 문헌고찰)

  • Jung, Ae-Ri;Lee, In-Sook
    • Perspectives in Nursing Science
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    • 제13권1호
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    • pp.48-57
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    • 2016
  • Purpose: The purpose of this study was to investigate the research methods, contents, and effects of providing information to alleviate patients' anxiety during outpatient surgery. Methods: The PICOTS-SD (Participants, Interventions, Comparisons, Outcomes, Time, Setting, Study design) was used and 11 randomized controlled trials studies that met the inclusion and exclusion criteria were selected. For assessing the quality of the studies, the Cochrane Risk of Bias tool was used. Results: In the 11 selected studies, intervention methods included verbal, written paper, video, and websites, and the outcome variable was anxiety. Regarding the effectiveness of providing information on anxiety, the result of the present study was ambivalent. Conclusion: This study showed the current trends in providing information as an intervention. However, randomized controlled trials are further needed in Korea, to verify the effects of such an intervention on patients' anxiety.

Performance Analysis of th e Sign Algorithm for an Adaptive IIR Notch Filter with Constrained Poles and Zeros

  • Tani, Naoko;Xiao, Yegui
    • Proceedings of the IEEK Conference
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    • 대한전자공학회 2000년도 ITC-CSCC -2
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    • pp.681-684
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    • 2000
  • Gradient-type algorithms for adaptive IIR notch filters are very attractive in terms of both performances and computational requirements. Generally, it is quite difficult to assess their performances analytically. There have been several trials to analyze such adaptive algorithms as the sign and the plain gradient algorithms for some types of adaptive IIR notch filters, but many of them still remain unexplored. Furthermore, analysis techniques used in those trials can not be directly applied to different types of adaptive IIR notch filters. This paper presents a detailed performance analysis of the sign algorithm for a well-known adaptive IIR notch filter with constrained poles and zeros, which can not be done by just applying the related existing analysis techniques, and therefore has not been attempted yet. The steady-state estimation error and mean square error (MSE) of the algorithm are derived in closed forms. Stability bounds of the algorithm are also assessed. extensive simulations are conducted to support the analytical findings.

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Correlation Analysis of Model Tests with Ship Powering Data for a 60,000 DWT Bulk Carrier (6만 DWT 산적화물선(散積貨物船) 모형선-실선(模型船-實船) 상관해석(相關解析))

  • Seung-Il,Yang;Chang-Sup,Lee;Eun-Chan,Kim
    • Bulletin of the Society of Naval Architects of Korea
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    • 제19권4호
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    • pp.61-70
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    • 1982
  • The hydrodynamic effects on resistance and propulsive performance were studied by using the data from model test and full scale speed trials. A series of model tests on 3 geosims for a 60,000 DWT Bulk Carrier was conducted at KIMM's Ship Experimental Towing Tank and the results analyzed by 1978 ITTC Performance Prediction Method show the correlation between 3 geosim models. Also powering data of full scale speed trials were analyzed by the newly developed computer program and the correlation analysis between ship and model was studied.

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