• 제목/요약/키워드: Trial Functions

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Comparison of Nasalance Score Between Glottal and Oral Articulation in Children with Velopharyngeal Insufficiency (연인두 폐쇄부전 아동의 보상조음과 정조음에서의 비음치 비교)

  • Lee, Eun-Kyung;Son, Young-Ik
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.18 no.2
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    • pp.129-133
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    • 2007
  • Background and Objectives: Nasometry is an easy, noninvasive method to obtain objective data regarding the function of velopharynx. However, because articulation errors may affect the results of nasometry, the examiner should interpret the nasalance score based on appropriate speech stimuli. The purpose of this study is to examine the difference of nasalance score between glottal and oral articulations in patients with velopharyngeal insufficiency (VPI). Materials and Method: Nineteen children between 3.4 and 12.1 years of age (mean age 5.7 years) with a confirmed VPl showing hypernasality and articulation errors (glottal stops) were included. Nasalance scores were obtained for two speech patterns of glottal and oral stops. In addition, the velopharyngeal functions were analyzed in four subjects using video nasopharyngoscopy. Results: The $mean{\pm}S.D$ nasalance scores of the glottal stops and oral stops were $42.54{\pm}16.26%$ and $25.47{\pm}16.51%$ respectively (p=.000). Six of 19 patients achieved normal nasalance scores when glottal stops changed to oral stops by the trial speech therapy. Video nasopharyngoscope confirmed that large velopharyngeal gaps can be decreased into tiny gaps or complete closure when compensatory articulations were corrected for some cases. Conclusion: Compensatory articulation errors must be corrected for the reliable interpretation of the nasalance scores that are obtained in children with velopharyngeal insufficiency, which would facilitate to make a better decision for further management of these patients.

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Reevaluation of the Necessity of Iron Injection to Newborn Piglets

  • Yu, I.T.;Lin, J.;Wu, J.F.;Yen, H.T.;Lee, S.L.;Yang, T.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.1
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    • pp.79-83
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    • 2002
  • The growth and immune responses to endotoxin lipopolysaccharide (LPS) challenge ( $20{\mu}g/kg$) of piglets with and without a iron dextran injection (Fe, 200 mg/head) two days after birth are compared. Sixty-four newborn piglets from eight litters were allocated randomly to one of four treatments. The control received no iron dextran and only saline (Sal) injection on the second and fifteenth day after birth (Sal-Sal). The remaining three groups received Fe-Sal, Sal-LPS, Fe-LPS treatments respectively. On fifteen days of age, blood samples of piglets were taken at 0 h, 1 h, 2 h and 4 d after saline or LPS injection to determine immune functions and blood characteristics. The trial terminated when the pig reached 56 days and the average daily gain of piglets was then measured. Daily gain, serum immunoglobulin G (IgG) concentration and red blood cell counts did not vary significantly among the four groups at any measuring times. Serum tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) concentration increased sharply 1 h after LPS injection. However, iron injection did not change TNF-${\alpha}$ concentration responds to LPS injection. White blood cell counts of two LPS injection groups were significantly lowered 1 h following the injection. In contrast, serum lactoferrin concentration had increased significantly 1 and 2 h postinjection. Furthermore, iron injection produced no further effects on these two criteria. Iron injection increased the hemoglobin (Hb) concentration of piglets at any measuring time, and LPS injection lowered Hb concentration. In conclusion, a 200 mg/head of iron dextran injection on the second day after birth increased Hb concentration, had no detrimental effect on the immune responses and growth of piglets. Moreover, if creep feed (175 mg Fe/kg feed) is provided from d 7 after birth, the Fe-injection does not contribute to overall performance of piglets and may not be a necessity in practice.

Vibration Analysis of Mindlin-Plate Structures having Attachments by the Receptance Method (Receptance 방법에 의한 부가물을 갖는 Mindlin판유추 구조제의 진동해석)

  • S.Y. Han;J.H. Chung
    • Journal of the Society of Naval Architects of Korea
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    • v.32 no.3
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    • pp.98-106
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    • 1995
  • In ship and offshore structures, there exist many local structural systems which may be regarded as a combined structural systems composed of thick plates or double wall panels and attachments reducible to damped spring-mass systems. For vibration analysis of such a combined system an analytical method based on the receptance method is presented in this paper. The free vibrational characteristics and forced vibration responses of the combined system can be calculated by synthesis of receptances of the panel and attachments. To calculate receptances of the panel, it may be regarded as a Mindlin plate for consideration of effects of shear deformation and rotary inertia and the assumed mode-Lagrange's equation method is applied using Timoshenko beam function or polynomials having properties of Timoshenko beam function as trial functions. Through some numerical calculations, accuracy and efficiency of the presented method are shown.

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In vitro and Lactation Responses in Mid-lactating Dairy Cows Fed Protected Amino Acids and Fat

  • Nam, I.S.;Choi, J.H.;Seo, K.M.;Ahn, J.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.12
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    • pp.1705-1711
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    • 2014
  • The objective of this study was to evaluate the effect of ruminally protected amino acids (RPAAs) and ruminally protected fat (RPF) supplementation on ruminal fermentation characteristics (in vitro) and milk yield and milk composition (in vivo). Fourteen mid-lactating Holstein dairy cows (mean weight $653{\pm}62.59kg$) were divided into two groups according to mean milk yield and number of days of postpartum. The cows were then fed a basal diet during adaptation (2 wk) and experimental diets during the treatment period (6 wk). Dietary treatments were i) a basal diet (control) and ii) basal diet containing 50 g of RPAAs (lysine and methionine, 3:1 ratio) and 50 g of RPF. In rumen fermentation trail (in vitro), RPAAs and RPF supplementation had no influence on the ruminal pH, dry matter digestibility, total volatile fatty acid production and ammonia-N concentration. In feeding trial (in vivo), milk yield (p<0.001), 4% fat corrected milk (p<0.05), milk fat (p<0.05), milk protein (p<0.001), and milk urea nitrogen (p<0.05) were greater in cows fed RPAAs and RPF than the corresponding values in the control group. With an index against as 0%, the rates of decrease in milk yield and milk protein were lower in RPAAs and RPF treated diet than those of basal diet group (p<0.05). In conclusion, diet supplemented with RPAAs and RPF can improve milk yield and milk composition without negatively affecting ruminal functions in Holstein dairy cows at mid-lactating.

Effect of Chitosan on Nitric Oxide Content and Inducible Nitric Oxide Synthase Activity in Serum and Expression of Inducible Nitric Oxide Synthase mRNA in Small Intestine of Broiler Chickens

  • Li, H.Y.;Yan, S.M.;Shi, B.L.;Guo, X.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.7
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    • pp.1048-1053
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    • 2009
  • The present study was conducted to determine the effects of chitosan on nitric oxide (NO) content and inducible nitric oxide synthase (iNOS) activity in serum, and relative expression of iNOS mRNA in the duodenum, jejunum, and ileum of broiler chickens. A total of 240 one-day-old Arbor Acre mixed-sex broiler chickens were randomly allotted to six dietary treatments with five replicates in each treatment and eight chickens in each replicate. The broiler chickens in the six treatments were fed the basal diet supplemented with 0 (control), 0.05, 0.2, 0.5, 1.0 or 2.0 g/kg chitosan. The trial lasted for 42 days. The results showed that dietary chitosan enhanced NO content and iNOS activity in serum as well as iNOS mRNA expression in the duodenum and ileum of broiler chickens in a quadratic dose-dependent manner (p<0.05), and improved jejunum iNOS mRNA expression in a quadratic dose-dependent manner (p<0.10) with increasing addition of chitosan. Chicks fed a diet containing 0.5-1.0 g/kg chitosan had higher NO content and iNOS activity in serum as well as small-intestinal iNOS mRNA expression compared with birds given the control diet, but positive effects of chitosan tended to be suppressed when addition of chitosan in the diet was increased to 2.0 g/kg. These results implied that there was a threshold level of chitosan inclusion beyond which progressive reductions in serum NO content and small intestinal iNOS expression occured, and the regulation of chitosan on immune functions in chickens is probably associated with activated expression of iNOS and NO secretion.

The Development of the Bi-directionally Personalized Broadcasting and the Targeting Advertisement System Based on the User Profile Techniques (사용자 프로파일 기반의 맞춤형 광고 서비스 및 양방향 개인 맞춤형 방송 시스템 구축)

  • Shin, Sa-Im;Lee, Jong-Soel;Jang, Se-Jin;Lee, Soek-Pil
    • Journal of Broadcast Engineering
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    • v.15 no.5
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    • pp.632-641
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    • 2010
  • This paper shows the research about the personalized broadcasting system. The personalized broadcasting is the service that users only show the programs which they want to watch when they want to watch these. The purpose of the bi-directional broadcasting service is supporting more satisfied and more personalized services by permitting the bi-directional data transformation. This research also develops the user profiling system for the bi-directional and personalized broadcasting service. This system applied the TV-Anytime metadata specifications which is the standard for the personalized broadcasting services, the system supports the various functions for the bi-directionl and personalized broadcasting such as the user profiling, contents metadata and targeting advertisement services. The bi-directional and personalized broadcasting system increases the users' satisfaction with the recommendation and management of the personally favorite broadcasting contents and advertisements, the trial run results show that the services raise the users' satisfaction with the intelligent and discriminating broadcasting services.

Changes in Sensory Function After Transcranial Direct Current Stimulation on Primary Motor Cortex Area

  • Min, Dong-Ki
    • Physical Therapy Korea
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    • v.21 no.4
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    • pp.1-8
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    • 2014
  • Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low-intensity direct current to cortical areas, thereby facilitating or inhibiting spontaneous neuronal activity. This study was designed to investigate changes in various sensory functions after tDCS. We conducted a single-center, single-blinded, randomized trial to determine the effect of a single session of tDCS with the current perception threshold (CPT) in 50 healthy volunteers. Nerve conduction studies were performed in relation to the median sensory and motor nerves on the dominant hand to discriminate peripheral nerve lesions. The subjects received anodal tDCS with 1 mA for 15 minutes under two different conditions, with 25 subjects in each groups: the conditions were as follows tDCS on the primary motor cortex (M1) and sham tDCS on M1. We recorded the parameters of the CPT a with Neurometer$^{(R)}$ at frequencies of 2000, 250, and 5 Hz in the dominant index finger to assess the tactile sense, fast pain and slow pain, respectively. In the test to measure CPT values of the M1 in the tDCS group, the values of the distal part of the distal interphalangeal joint of the second finger statistically increased in all of 2000 Hz (p=.000), 250 Hz (p=.002), and 5 Hz (p=.008). However, the values of the sham tDCS group decreased in all of 2000 Hz (p=.285), 250 Hz (p=.552), and 5 Hz (p=.062), and were not statistically significant. These results show that M1 anodal tDCS can modulate sensory perception and pain thresholds in healthy adult volunteers. The study suggests that tDCS may be a useful strategy for treating central neurogenic pain in rehabilitation medicine.

Use of 3D Printing Model for the Management of Fibrous Dysplasia: Preliminary Case Study

  • Choi, Jong-Woo;Jeong, Woo Shik
    • Journal of International Society for Simulation Surgery
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    • v.3 no.1
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    • pp.36-38
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    • 2016
  • Fibrous dysplasia is a relatively rare disease but the management would be quite challenging. Because this is not a malignant tumor, the preservation of the facial contour and the various functions seems to be important in treatment planning. Until now the facial bone reconstruction with autogenous bone would be the standard. Although the autogenous bone would be the ideal one for facial bone reconstruction, donor site morbidity would be the inevitable problem in many cases. Meanwhile, various types of allogenic and alloplastic materials have been also used. However, facial bone reconstruction with many alloplastic material have produced no less complications including infection, exposure, and delayed wound healing. Because the 3D printing technique evolved so fast that 3D printed titanium implant were possible recently. The aim of this trial is to try to restore the original maxillary anatomy as possible using the 3D printing model, based on the mirrored three dimensional CT images based on the computer simulation. Preoperative computed tomography (CT) data were processed for the patient and a rapid prototyping (RP) model was produced. At the same time, the uninjured side was mirrored and superimposed onto the traumatized side, to create a mirror-image of the RP model. And we molded Titanium mesh to reconstruct three-dimensional maxillary structure during the operation. This prefabricated Titanium-mesh implant was then inserted onto the defected maxilla and fixed. Three dimensional printing technique of titanium material based on the computer simulation turned out to be successful in this patient. Individualized approach for each patient could be an ideal way to restore the facial bone.

Proposals for New Regulations Concerning Consumer ADR and ODR and their Implications in the EU (EU의 소비자 ADR 및 ODR에 관한 새로운 규정 논의와 국내에의 시사점)

  • Son, Hyun
    • Journal of Arbitration Studies
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    • v.23 no.1
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    • pp.107-131
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    • 2013
  • Online-ADR (Alternative Dispute Resolution) has been receiving attention from the international community as a means of alternative dispute resolution for consumer disputes in both small and mass international e-commerce. The EU Parliament and the Council proposed the Online Dispute Resolution Regulation for Consumer Disputes (hereafter, "EU Consumer ODR Regulation") and the Directive on Alternative Dispute Resolution of Consumer Disputes (hereafter, "EU Consumer ADR Directive") as a legislative package, now scheduled to be adopted. Those efforts strengthen consumer protection by enhancing ODR in international e-commerce and improving of the functions of the e-commerce market. The EU Consumer ADR and ODR regulation package will operate in conjunction with the ODR platform as a single point across Europe, abandoning the ADR system of each member. Consumers and traders who need dispute resolution apply on the EU ODR platform linked website, and the applications are distributed to individual ADR institutions in accordance with the Rules and Procedure of ADR institutions in the respective country. Although there has been partial progress in Korea for ODR programs such as the establishment of the Online Administrative Trial and the procedures of individual ADR agencies operating through the website, existing norms do not fully support the system. At this point, we see many implications of the EU Consumer ADR and ODR regulation package on the direction chosen for domestic ADR and ODR policy and legislation. This study introduces the main features and content of the EU Consumer ADR Directive (draft) and ODR Regulation provisions, and describes the direction of domestic policy and legislation regarding Online-ADR.

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Determination of Optimal Unit Hydrographs and Infiltration Rate Functions at the site of the Su-Jik Bridge in the HwangGuJichen River (황구지천 수직교 지점에서의 최적 단위도 및 침투율의 결정)

  • Ahn, Taejin;Cho, Byung Doon;Lyu, Heui Jeong
    • Journal of Wetlands Research
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    • v.7 no.3
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    • pp.57-66
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    • 2005
  • This paper is to present the determination of the optimal loss rate parameters and unit hydrographs from the observed single rainfall-runoff event using optimization model. The linear program models has been formulated to derive the optimal unit hydrographs and loss rate parameters for the site of the Su-Jik Bridge in the HwangGuJichen River; one minimizes the summation of the absolute residual between predicted and observed runoff ordinates. In the perturbation stage of parameters the trial and error method has been adopted to determine the loss rate parameters for Kostiakov's, Philip's, Horton's, and Green-Ampt's equation. The unique unit hydrograph ordinates for a given rainfall-runoff event is exclusively obtained with ${\Phi}$ index, but unit hydrograph ordinates depend upon the parameters for each loss rate equations. In this paper the single rainfall-runoff event observed from the sample watershed is considered to test the proposed method. The optimal unit hydrograph obtained by the optimization model has smaller deviations than the ones by the conventional method.

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