• Title/Summary/Keyword: Trial Division

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Functional Electrical Stimulation with Augmented Feedback Training Improves Gait and Functional Performance in Individuals with Chronic Stroke: A Randomized Controlled Trial

  • Yu, Kyung-Hoon;Kang, Kwon-Young
    • The Journal of Korean Physical Therapy
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    • v.29 no.2
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    • pp.74-79
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    • 2017
  • Purpose: The purpose of this study was to compare the effects of the FES-gait with augmented feedback training to the FES alone on the gait and functional performance in individuals with chronic stroke. Methods: This study used a pretest and posttest randomized control design. The subjects who signed the agreement were randomly divided into 12 experimental groups and 12 control groups. The experimental groups performed two types of augmented feedback training (knowledge of performance and knowledge of results) together with FES, and the control group performed FES on the TA and GM without augmented feedback and then walked for 30 minutes for 40 meters. Both the experimental groups and the control groups received training five times a week for four weeks. Results: The groups that received the FES with augmented feedback training significantly showed a greater improvement in single limb support (SLS) and gait velocity than the groups that received FES alone. In addition, timed up and go (TUG) test and six minute walk test (6MWT) showed a significant improvement in the groups that received FES with augmented feedback compared to the groups that received FES alone. Conclusion: Compared with the existing FES gait training, augmented feedback showed improvements in gait parameters, walking ability, and dynamic balance. The augmented feedback will be an important method that can provide motivation for motor learning to stroke patients.

A Study on the Field test of the Ready-mixed Shotcrete using in the Large-scale Mine (광산 대규격 갱도에 대한 레디믹스트 숏크리트의 현장 적용성 평가)

  • Kim, Dong-Min;Lee, Heung-Soo;Shin, Hong-Jun;Kang, Dong-Jun
    • Proceedings of the Korean Geotechical Society Conference
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    • 2009.09a
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    • pp.1511-1516
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    • 2009
  • In recent years, the large-scale shaft have been appling in domestic mine for mass production using a large machine, the safety of mine also have been increasing. And the new trial that shotcrete of tunnel field was apply to mine support was progressed. But, the conditions of domestic mine was different from that of tunnel, so, the batch plant of tunnel could not be installed in mine field because of low economical efficiency and difficulty for selection of site. Ready-mixed Shotcrete that mixed with high quality materials and could be controled shotcrete quality is producted in plants and transported to field, so do not need to batch plant. In this study, The Field test of the Ready-mixed Shotcrete was performed in the large-scale mine and was compared with the quality of Field mix shotcrete. As the result of the Field test, compressive strength and rebound of Ready-mixed Shotcrete were superior to these of Field mix shotcrete.

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MRI-Guided Gadolinium Neutron Capture Therapy

  • Ji-Ae Park;Jung Young Kim;Hee-Kyung Kim
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.8 no.2
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    • pp.113-118
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    • 2022
  • Gadolinium neutron capture therapy (Gd-NCT) is a precision radiation therapy that kills cancer cells using the neutron capture reaction that occurs when 157Gd hits thermal neutrons. 157Gd has the highest thermal neutron capture cross section of 254,000 barns among stable isotopes in the periodic table. Another stable isotope, 155Gd, also has a high thermal neutron trapping area (~ 60,700 barns), so gadolinium that exists in nature can be used as a Gd-NCT drug. Gd-NCT is a mixed kinetic energy of low-energy and high-energy ionizing particles, which can be uniformly distributed throughout the tumor tissue, thereby solving the disadvantage of heterogeneous dose distribution in tumor tissue. The Gd complexes of small-sized molecule are widely used as contrast agents for magnetic resonance imaging (MRI) in clinical practice. Therefore, these compounds can be used not only for diagnosis but also therapy when considering the concept of Gd-NCT. This multifunctional trial can look forward to new medical advance into NCT clinical practices. In this review, we introduce gadolinium compounds suitable for Gd-NCT and describe the necessity of image guided Gd-NCT.

Differential Effects of Two Individual Acupuncture Points (BL62, KI6) on Heart Rate Variability in Healthy Volunteers : A Randomized, Single-Blind, Self-Controlled Trial (건강한 지원자에서 두 경혈(신맥, 조해)이 심박변이도에 미치는 영향의 차이 : 무작위, 단일 맹검, 자기 대조군 임상시험)

  • Lee, Ji-Hye;Choi, Young-Joon;Shin, Byung-Chul;Koo, Sung-Tae
    • Korean Journal of Acupuncture
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    • v.27 no.4
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    • pp.85-97
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    • 2010
  • 목적 : 이 연구는 서로 다른 두 경혈이 심박변이도에 미치는 영향을 비교하고, 자율신경계에 미치는 영향을 평가하기 위해 수행하였다. 재료 및 방법 : 13명의 지원자가 3개의 세션에 균등하게 무작위 배정되었다. 각 세션에서 지원자들은 신맥(BL62), 조해(KI6), 또는 비경혈에 각각 침처치를 받았다. 10분간 휴식을 한 후에 자침 전, 유침기간, 발침 후 기간에 5분 동안 심박변이도 측정을 하였다. 유침기간에는 2분 간격을 두고 2회 심박변이도를 측정하였다. 결과 : 신맥에 자침한 군에서는 자침후 기간에 total power(TP)와 standard deviation N-N interval(SDNN)이 유의하게 증가하였다. 유침기간 중 첫 5분 동안의 TP와 SDNN은 자침전 값과 유의한 차이가 없었으며 유침기간 중 마지막 5분 동안에는 다소 증가하는 경향은 있었지만 통계적인 유의성은 없었다. 반면에 조해와 비경혈에 자침한 군에서는 TP와 SDNN에 유의한 변화가 관찰되지 않았다. 발침 후에 신맥자침군에서는 조해와 비경혈 자극군과 비교해서 TP가 유의하게 변화하였다. 그러나 SDNN은 발침 후에 세 군 사이에 유의한 차이가 없었다. 결론 : 이 실험 결과는 조해와 비교했을 때 신맥에 자침한 경우 심장 기능 및 자율신경계와 관련이 있는 대체적인 활성이 증가한다는 것을 보여주었다. 이 결과는 신맥 자침이 자율신경계와 관계되어 있는 심장의 기능에 미치는 영향을 통해서 경혈의 특이성을 관찰할 수 있음을 의미한다.

Indoor and Outdoor Reception Performance Evaluation of Digital Radio Techniques in Field Trials (디지털라디오 방송의 실내외 수신 환경을 고려한 필드 테스트 성능 평가)

  • Kim, Joo-Seok;Baek, Myung-Sun;Lee, Yong-Hoon;Lee, Yong-Tae;Kim, Kyung-Seok
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.11 no.1
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    • pp.1-11
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    • 2018
  • This paper provides field test results to confirm and compare the receiving characteristics of digital radio in various environments. HD Radio and DRM+ was used for the in-band method, while DAB/DAB+/T-DMB were used for the out-of-band method. To run field tests for digital radio, a transceiver test bed was constructed in a region in Korea selected as suitable for the testing, and indoor and outdoor reception tests were conducted by selecting 16 test points with different levels of multipath. Not only was the receivability tested at the test point, but ATT margin was also applied, in order to derive the minimum reception level. Through various analyses, the findings obtained through the field tests can aid in the setting of a standard for determining the method of digital radio transmission to ensure a smooth reception environment for consumers.

Development of Clinical Protocol for Acquisition of Change of Radial Pulse Wave Signal in the Cold-Heat Intervention: Explanatory, Randomized, 2×2 cross-over design (냉온 부하에 따른 요골동맥 맥파의 변화 특성을 파악하기 위한 무작위 배정·2×2교차설계 탐색적 임상시험계획서 개발)

  • Yu, Hana;Kim, Jihye;Ku, Boncho;Kim, Hyunho;Jeon, Youngju
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.19 no.2
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    • pp.91-100
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    • 2015
  • Objectives The aim of this study is to develop a structured clinical protocol related with acquisition of radial pulse wave in the randomized, $2{\times}2$ cross-over design, and cold-heat intervention trial for a pilot and preliminary study. Methods The protocol was contrived based on wide ranging literature searches for cold-heat intervention experiments and radial pulse diagnoses. Results Sample size of 60 subjects was calculated based on an effect size derived from the previous study designed to detect the pre-post cold-heat differences in the radial pulse. Each subjects will be randomly assigned to the cold (first) to heat (last) group (n=30) or heat (first) to cold (last) group (n=30). All subjects will fill out a case report form and questionnaires related with pattern identification, dietary patterns, sleep quality, and physical activity will be surveyed and used as a secondary outcomes. Safety assessment will be reported at the final stage. Conclusions This protocol will provide an additional reference to future studies related with observation of radial pulse during any interventions and also expect to be used as a guideline for acquisition of reliable radial pulse wave data.

Control Law Design for a Tilt-rotor Unmanned Aerial Vehicle with a Nacelle Mounted WE (Wing Extension) (체공성능 향상을 위한 확장날개 틸트로터 무인기의 제어법칙설계)

  • Kang, Young-Shin;Park, Bum-Jin;Cho, Am;Yoo, Chang-Sun
    • Journal of Institute of Control, Robotics and Systems
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    • v.20 no.11
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    • pp.1103-1111
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    • 2014
  • The results of control law design for a tilt-rotor unmanned aerial vehicle that has a nacelle mounted wing extension (WE) are presented in this paper. It consists of a control surface mixer, stability and control augmentation system (SCAS), hold mode for altitude / speed / heading, and a guidance mode for preprogram and point navigation which includes automatic take-off and landing. The conversion corridor and the control moments derivatives between the original tilt-rotor and its variant of the nacelle mounted WE were compared to show the effectiveness of the WE. The nacelle conversion of the original tilt-rotor starts when the airspeed is greater than 30 km/h but its WE variant starts at 0 km/h in order to reduce the drag caused by the high incidence angle of the WE. The stability margins of the inner loop are presented with the optimization approach. The outer loops for the hold mode are designed with trial and error methods with linear and nonlinear simulation. The main control parameter for altitude control of the helicopter mode is thrust command and it is transferred to the pitch attitude command in airplane mode. Otherwise, the control parameter for the speed of the helicopter mode is the pitch attitude command and it is transferred to the thrust command in airplane mode. Therefore the speed and altitude hold mode are coupled to each other and are engaged at the same time when an internal pilot engages any of the altitude or speed hold modes. The nonlinear simulation results of the guidance control for the preprogrammed mode and point navigation are also presented including automatic take-off and landing in order to prove the full control law.

A Simple and Rapid Method for Functional Analysis of Plant Growth-promoting Rhizobacteria Using the Development of Cucumber Adventitious Root System

  • Bae, Yeoung-Seuk;Park, Kyung-Seok;Lee, Young-Gee;Choi, Ok-Hee
    • The Plant Pathology Journal
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    • v.23 no.3
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    • pp.223-225
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    • 2007
  • Many plant growth-promoting rhizobacteria (PGPRs) have been known for beneficial effects on plants including biological control of soilborne pathogens, induced systemic resistance to plant pathogens, phytohormone production, and improvement of nutrient and water uptake of plants. We developed a simple and rapid method for screening potential PGPR, especially phytohormone producing rhizobacteria, or for analyzing their functions in plant growth using cucumber seedling cuttings. Surface-sterilized cucumber seeds were grown in a plastic pot containing steamed vermiculite. After 7 days of cultivation, the upper part 2 cm in length of cucumber seedling, was cut and used as cucumber cuttings. The base of cutting stem was then dipped in a microcentrifuge tube containing 1.5ml of a bacterial suspension and incubated at $25^{\circ}C$ with a fluorescent light for 10 days. Number and length of developed adventitious roots from cucumber cuttings were examined. The seedling cuttings showed various responses to the isolates tested. Some isolates resulted in withering at the day of examination or in reduced number of roots developed. Several isolates stimulated initial development of adventitious roots showing more adventitious root hair number than that of untreated cuttings, while some isolate had more adventitious root hair number and longer adventitious roots than that of untreated control. Similar results were obtained from the trial with rose cuttings. Our results suggest that this bioassay method may provide a useful way for differentiating PGPR's functions involved in the development of root system.

Effects Of Grass/Legume Pasture on Forage Production, Forage Nutritive Values and Live Weight Gain of the Grazing Heifer

  • Seo, Sung;Lee, J.K.;Shin, D.E.;Chung, E.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.3
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    • pp.289-292
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    • 1997
  • A grazing trial was carried out to determine the effects of different grass/legume pastures on forage production, legume proportion, nutritive value, and animal performance. The pasture mixtures were mainly orchardgrass (OG) + ladino clover (T1), OG + alfalfa (T2), perennial ryegrass + alfalfa (T3), and grass alone mainly OG (T4). The pastures were rotationally grazed 7 times with heifers which had an initial liveweight of about 243 kg in 1991 and 1992. The average plant height at each grazing was 32.4 cm. The annual dry matter yield ranged from 9.19 MT in T4 to 9.61 MT/ha in T3, but no significant difference among different mixture combinations was found. The proportion of ladino clover in T1 mixtures rapidly increased from 21% to 68% during the grazing season. However, the proportion of alfalfa in T2 and T3 ranged from 12% to 23%. The contents of crude protein and calcium, respectively, in the forages were highest in T1 (23.2%, 0.68%) and lowest in T4 (18.5%, 0.13%), while crude fiber content showed the opposite trends. Liveweight gain was greatest on T1 (1.073 kg) and lowest on T4 (643 kg). It was concluded that pasture mixtures containing legume (ladino clover) can increase forage nutritive value and animal performance.

Applicability of Radioguided Occult Lesion Localization for Non-Palpable Benign Breast Lesions, Comparison with Wire Localization, a Clinical Trial

  • Alikhassi, Afsaneh;Saeed, Farzanefar;Abbasi, Mehrshad;Omranipour, Ramesh;Mahmoodzadeh, Habibollah;Najafi, Massoome;Gity, Masoumeh;Kheradmand, Ali
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.7
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    • pp.3185-3190
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    • 2016
  • Background: This study was designed to compare radioguided versus routine wire localization of nonpalpable non-malignant breast lesions in terms of efficacy for complete excision, ease of use, time saving, and cosmetic outcome. Materials and Methods: Patients with non-palpable breast masses and non-malignant core biopsy results who were candidates for complete surgical lumpectomy were enrolled and randomly assigned to radioguided or wire localization groups. Radiologic, surgical, and pathologic data were collected and analyzed to determine the difficulty and duration of each procedure, ease of use, accuracy, and cosmetic outcomes. Results: This prospective randomized study included 60 patients, randomly divided into wire guided localization (WGL) or radioguided occult lesion localization (ROLL) groups. The mean duration of localization under ultrasound guidance was shorter in the ROLL group (14.4 min) than in the WGL group (16.5 min) (p<0.001). The ROLL method was significantly easier for radiologists (p=0.0001). The mean duration of the surgical procedure was 22.6 min (${\pm}10.3min$) for ROLL and 23.6 min (${\pm}9.6min$) for WGL (p=0.6), a non-significant difference. Radiography of the surgical specimens showed 100% lesion excision with clear margins, as proved by pathologic examination, with both techniques. The surgical specimens were slightly heavier in the ROLL group, but the difference was not significant (p=0.06). Conclusions: The ROLL technique provides effective, fast, and simple localization and excision of non-palpable non-malignant breast lesions.