• Journal of Cardiovascular Imaging
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• v.31 no.3
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• pp.135-141
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• 2023

BACKGROUND: Global longitudinal strain (GLS) is an accurate and reproducible parameter of left ventricular (LV) systolic function which has shown meaningful prognostic value. Fast, user-friendly, and accurate tools are required for its widespread implementation. We aim to compare a novel web-based tool with two established algorithms for strain analysis and test its reproducibility. METHODS: Thirty echocardiographic datasets with focused LV acquisitions were analyzed using three different semi-automated endocardial GLS algorithms by two readers. Analyses were repeated by one reader for the purpose of intra-observer variability. CAAS Qardia (Pie Medical Imaging) was compared with 2DCPA and AutoLV (TomTec). RESULTS: Mean GLS values were -15.0 ± 3.5% from Qardia, -15.3 ± 4.0% from 2DCPA, and -15.2 ± 3.8% from AutoLV. Mean GLS between Qardia and 2DCPA were not statistically different (p = 0.359), with a bias of -0.3%, limits of agreement (LOA) of 3.7%, and an intraclass correlation coefficient (ICC) of 0.88. Mean GLS between Qardia and AutoLV were not statistically different (p = 0.637), with a bias of -0.2%, LOA of 3.4%, and an ICC of 0.89. The coefficient of variation (CV) for intra-observer variability was 4.4% for Qardia, 8.4% 2DCPA, and 7.7% AutoLV. The CV for inter-observer variability was 4.5%, 8.1%, and 8.0%, respectively. CONCLUSIONS: In echocardiographic datasets of good image quality analyzed at an independent core laboratory using a standardized annotation method, a novel web-based tool for GLS analysis showed consistent results when compared with two algorithms of an established platform. Moreover, inter- and intra-observer reproducibility results were excellent.

• Clinical Nutrition Research
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• v.13 no.1
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• pp.22-32
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• 2024

Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disorder with widespread synovitis. Isoflavones, the main active component of soy, have been reported to have potent anti-inflammatory effects; the previous RA animal models showed the promising effect of soy supplementation. We aimed to evaluate the effect of soy bread on inflammatory markers and lipid profiles in RA patients. The present study was designed as a randomized controlled trial. RA patients were randomly allocated to obtain soy bread (n = 22) or placebo bread (n = 22) for 8 weeks. Fasting serum levels of lipid profile, total antioxidant capacity (TAC), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), and DAS28 were checked. Findings showed that there were no significant differences between the two groups in physical activity and dietary intake at the beginning of the study and the end of the study. There were no significant differences between the two groups in measured lipid profile markers, including high-density lipoprotein, low-density lipoprotein, total cholesterol, triglyceride, and very low-density lipoprotein, at the end of the trial. In addition, TAC and CRP also were not significant at the end of the trial between the 2 groups (0.66 and 0.12, respectively). However, the serum levels of TNF-α reduced significantly in the soy bread group at the end of the intervention (p < 0.000) and compared with the control group (p < 0.019). Soy bread consumption only decreased circulating TNF-α serum concentration. Other outcome measures were not changed following supplementation. Future long-term, well-designed studies are needed to confirm these findings.

• International Journal of Industrial Entomology and Biomaterials
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• v.15 no.1
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• pp.39-45
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• 2007

Extracts of adult worker bodies of Vespa simillima in 2 % NaCl or acidified methanol were administered orally to mice for 70 days. Following this period, memory at one-day and one-month periods, and the effects on scopolamine-induced amnesia were examined using a step-through passive avoidance task. Changes in MK-801-induced disability after 8 days of training, and in memory one month after the trial were also assessed. Mice treated with the 2% NaCl extract showed significant improvement in memory in the behavioral tests one month after the trial, whereas mice receiving the extract in acidified methanol, did not differ from the controls in any trial. The results inidicate that Vespa simillima contains substances acting favorably on the cerebral functions of mammals.

• The Journal of Fisheries Business Administration
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• v.44 no.3
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• pp.29-46
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• 2013

The purpose of this study is to evaluate the economic validity of artificial reefs facilities and seeds release programs in Jeju Trial Sea Farm Project for raising fishing people's revenue. The results of this study show the artificial reefs facilities and seeds release programs have net present value of 15,962.63 million won, internal rate of retrurn 13.86%, and benefit-cost of 1.912 under a 5.5% social discount rate. This suggests that in Jeju trial sea farm project, artificial reefs facilities and seeds release programs increase fisherperson's revenue.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.1724-1726
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• 2003

Korean High-Speed Train (350km/h), composed of 2 power cars, 2 motorized car and 3 trailer cars, has been developed and is under trial test. To verify the design requirements for the functions and traction performances of the train, KRRI (Korea Railroad Research Institute) decided to evaluate traction performances of the train during trial test. For this purpose, torque, velocity, voltage and current must be measured. KRRI has developed a measurement system that can measure vast and various signals effectively. In this paper, we introduce traction performances of Korean High-Speed Train. The traction measurement items are focused on the verification of motor block performances. Motor block consists of 2 motors. By this test, we verified traction performances of Korean High-Speed Train.

• Journal of the Korean Society of Marine Environment & Safety
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• v.26 no.3
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• pp.269-276
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• 2020

Sea trial tests are necessary to verify speed-power performance, and are an import contract between ship owners and shipyards. The International Organization for Standardization (ISO) published ISO 15016:2015, which specifies the correlation method between model and full-scale ships. The results of sea trials have been questioned because of the uncertainty of speed and power measurements, especially when sea conditions differ from ideal calm water conditions. In this paper, such uncertainties were investigated by utilizing the standard speed-power trial analysis procedure defined in ISO 15016:2015 through Monte Carlo simulations. It was found that the expanded uncertainty of the delivered power (P_Did) at 95 % confidence interval (k = 2) was ±1.5 % under 75 % MCR conditions.

• The Korean Journal of Applied Statistics
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• v.9 no.2
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• pp.135-143
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• 1996

In surveys on certain social problems which are sensitive in nature, many techniques have been introduced in order to protect evasive or untruthful answers. We suggest a multiple trial randomized response technique(MRRT) and it turns out that MRRT is feasible and more efficient by reducing the variance of the estimate than single trial RRT's investigated by Warner(1965), Mangat & Singh(1990), Mangat(1994).

• Journal of Korean Library and Information Science Society
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• v.35 no.4
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• pp.41-63
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• 2004

This study is an analysis of the prisoners' and the pre-trial prisoners' rights based on the laws and rules, and court cases. Rights included are the right to know and the access to information, the right to legal representation and the right of education, all of them can be protected when the prison libraries are administered In order to protect the prisoners' and pre-trial prisoners' rights, the necessity for the establishment of prison library is discussed and the direction of prison library system is suggested.

• Journal of Advanced Marine Engineering and Technology
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• v.15 no.5
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• pp.47-54
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• 1991

The lip seals widely used nowadays in stern tube sealing system of ships have radial sealing contact with shafts or liners, on the other hand the face seals of stern tube sealing system have axial sealing contact with seat. Because of axial sealing contact, the face seals have a large number of merits such as durability of life, simplicity of structure, easy fitting and replacement, etc. In this paper, for the purpose of development of face seals, the fundamental properties of axial sealing contact were analyzed and a trial face seal was designed and manufactured using N.B.R. rubber and Thordon which is widely used for bearing materials. The seal proper of trial face seal was made from N.B.R. rubber and the face insert was made from Thordon, thermosetting resins which are three dimensional, cross linked condensation polylmers. The performance test of trial face seal was carried out on the test bench which was specially designed and manufactured. The results were satisfactory enough to be used in practical stern tube sealing system.

• Communications for Statistical Applications and Methods
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• v.19 no.1
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• pp.57-64
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• 2012

Phase I clinical trials determine the maximum tolerated dose(MTD) of a new drug. In this paper, we proposed a two-stage MTD estimation method by a Stopping rule in a phase I clinical trial. The suggested MTD estimation method is compared to the standard design(SM3) and the continual reassessment method(CRM) using a Monte Carlo simulation study.