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The Effect of Vespa simillima Extracts on Long-Term Memory and MK-801-Induced Learning Disability in Mice  

Fujiwara, Yumiko (Department of Agro-Bioscience, Faculty of Agriculture, Iwate University)
Kobayashi, Haruo (Department of Veterinary Medicine, Faculty of Agriculture, Iwate University)
Kawai, Shigenao (Department of Applied Biochemistry, Faculty of Agriculture, Iwate University)
Suzuki, Koichi (Department of Agro-Bioscience, Faculty of Agriculture, Iwate University)
Publication Information
International Journal of Industrial Entomology and Biomaterials / v.15, no.1, 2007 , pp. 39-45 More about this Journal
Abstract
Extracts of adult worker bodies of Vespa simillima in 2 % NaCl or acidified methanol were administered orally to mice for 70 days. Following this period, memory at one-day and one-month periods, and the effects on scopolamine-induced amnesia were examined using a step-through passive avoidance task. Changes in MK-801-induced disability after 8 days of training, and in memory one month after the trial were also assessed. Mice treated with the 2% NaCl extract showed significant improvement in memory in the behavioral tests one month after the trial, whereas mice receiving the extract in acidified methanol, did not differ from the controls in any trial. The results inidicate that Vespa simillima contains substances acting favorably on the cerebral functions of mammals.
Keywords
Vespa simmillima; Body extract; Memory; Learning; Improvemnet;
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1 Coan, E.J., W. Saywood and G. L. Collingridge (1987) MK-801 blocks NMDA receptor-mediated synaptic transmission and long term potentiation in rat hippocampal slices. Neurosci. Letters 80, 111-114   DOI   ScienceOn
2 Das, A., G. Shanker, C. Nath, R. Pal, S. Singh and H. K. Singh (2002) A comparative study in rodents of standardized extracts of Bacopa monniera and Ginkgo biloba anticholinesterase and cognitive enhancing activities. Pharmacol. Biochem. Behav. 73, 893-900   DOI   ScienceOn
3 Espinola, E.B., R.F. Dias, R. Mattei and E.A. Carlini (1997) Pharmacological activity of Guarana (Paullinia cupana Mart.) in laboratory animals. J. Ethnopharmacol. 55, 223-229   DOI   ScienceOn
4 Gan, M., D. Wan, X. Qin and P. Gao (2006) Pharmacological study on Samia cynthia ricini in old female mice. J. Ethnopharmacol. 105, 210-214   DOI   ScienceOn
5 Matsuura, M.(1971) Nest foundation by the female wasps of the genus: Vespa (Hymenoptera, Vespidae). Kontyii 39, 99-105
6 Morris, R.G.M. (1981) Spatial localization dose not require the presence of local cues. Learn. Motiv. 12, 239-260   DOI
7 Nakajima, T. (1986) Pharmacological biochemistry of vespid venoms; in Venoms of the Hymenoptera. Piek, T.( eds.), pp. 309-327, Academic Press, London
8 Naya, S., A. Sagisaka and K. Suzuki (1994) Identification of a maturation factor inducing post-diapause development in pharate first-inster larvae of the Wild Silkmoth, Antheraea yamamai. Int. J. Wild Silkmoth & Silk 1, 195-200
9 Nobili, L. and W.G. Sannita (1997) Cholinergic modulation, visual function and Alzheimer's demensia. Vision Res. 37, 3559-3571   DOI   ScienceOn
10 Ramirez-Amaya, V., I. Balderas, J. Sandoval, M.L. Escobar and F. Bermudez-Rattoni (2001) Spatial long-term memory is related to mossy fiber synaptogenesis. J. Neurosci. 21, 7340-7348   DOI
11 Tanaka, H., K. Sato, Y. Saito, T. Yamashita, M. Agoh, J. Okunishi, E.T achikawa and K. Suzuki (2003) Insect diapausespecific peptide from the leaf beetle has consensus with a putative iridovirus peptide. Peptides 24, 1327-1333   DOI   ScienceOn
12 Vecht, J. van der (1959) Notes on Oriental Vespinae, including some species from China and Japan (Hymenoptera, Vespidae). Zool. Med. Leiden 16, 205-232
13 Xu, J., Y. Murakami, K. Matsumoto, M. Tohda, H. Watanabe, S. Zhang, Q. Yu and J. Shen (2000) Protective effect of Oren-gedoku-to (Huang-Lian-Jie-Du-Tang) against impairment of learning and memory induced by transient cerebral ischemia in mice. J. Ethnopharmacol. 73, 405-413   DOI   ScienceOn
14 Wahrendorf, M.-S. and M. Wink (2006) Pharmacologically active natural products in the defence secretion of Palembus ocularis (Tenebrionidae, Coleoptera). J. Ethnopharmacol. 106,51-56
15 Zhang, Y., Y. Shioyama, M. Sugiura and H. Saito (1994) Effects of Crocus sativus L. on the ethanol-induced impairment of passive avoidance performances in mice. Biol Pharm. Bull. 17, 217-221   DOI   ScienceOn
16 Cherubini, E., A.Y. Ben, M. Gho, J. N. Bidard and M. Lazdunski (1987) Long-term potentiation of synaptic transmission in the hippocampus induced by a bee venom peptide. Nature 328, 70-73   DOI   ScienceOn
17 Yoshimura, K. (1946) Pharmacological study of Vespae nidus. Proceedings of the 19th Congress of Japanese Pharmacological Society, 7-8 (in Japanese)
18 Jin, S.-H., J.-K. Park, K.-Y. Nam, S.-N. Park and N.-P.Jung (1999) Korean red ginseng saponins with low ratios of protopanaxadiol and protopanaxatriol saponin improve scopolamine-induced learning disability and spatial working memory in mice. J. Ethnopharmacol. 66, 123-129   DOI   ScienceOn
19 Donohoe, R.T. and D. Benton (2000) Glucose tolerance predicts performance on tests of memory and cognition. Physiol. Behav. 71, 395-401   DOI   ScienceOn
20 Yamazaki, T., M. Yaguchi, Y. Nakajima, T. Hosono, Y. Niiho, Y. Hibi, J. Kinjo and T. Nohara (2005) Effects of aqueous extract of Puerariae flos (Thomsonide) on impairment of passive avoidance behavior in mice. J. Ethnopharmacol. 100, 244-248   DOI   ScienceOn
21 Yamaguchi, Y., M. Higashi and H. Kobayashi (1996) Effects of ginsenosides on impaired performance caused by scopolamine in rats. Eur. J. Pharmacol. 312, 149-151   DOI   ScienceOn
22 Hong, Z.Y. (1960) Effects of the extract from Vespae nidus on blood coagulation and heart movement. J. Osaka Med. Coll. 20, 739-741 (in Japanese)
23 Wright, R. J. and T. Stuczynski (1996) Atomic absorption and flame emission spectrometry; in Methods of Soil Analysis part $3{\AA}$]Chemical Methods, Book Series: 5, Soil Science Society of America, pp. 65-90, Inc. America Society of Agronomy, Inc. Madison, Wisconsin, USA
24 Coyle, J.T., D.L. Price and M.R Delong (1983) Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 219, 1184-1190   DOI
25 Tsai, G., R.J. Ralph-Williams, M. Martina, R. Bergeron, J. Berger-Sweeney, K.S. Dunham, Z. Jiang, S.B. Caine and J.T. Coyle (2004) Gene knockout of glycine transporter 1: Characterization of the behavioral phenotype. Proc. Natl. Acad. Sci. USA 101, 8485-8490