• 제목/요약/키워드: Trend of clinical research

검색결과 343건 처리시간 0.026초

C. M. I 반응에 의한 간호원의 심신 건강 평가 (Psychiatric Evaluation of Nurses by C. M. I.)

  • 방용자
    • 대한간호학회지
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    • 제7권2호
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    • pp.107-116
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    • 1977
  • It is a well accepted fact that mental and physical health of nurses has a direct bearing or influence in their practice in the nursing profession. Recently, with this view in mind, the study of the mental and physical health of nurses has attracted the attention of many especially those in research hospitals. According to Soon Hyang Cha(1974) a nurse in clinical practice or service has a daily energy consumption of 39% and San Cho Chun (1974) asserts that Nurses'duties are more demanding on her emotionally than on her nursing technical skills. Many more studies has been made to this effect, here and abroad and similarly stressed the importance of mental and physical health for nurses. This study was made in an attempt to analyze the trend or tendency of the mental and physical health of nurses by employing the Cornell Medical Index (CMI) method. The data has been collected from May 1977 to November 1977, 200 nurses from 8 University hospitals and 200 nurses from general hospitals in Seoul, Theses who participated were selected at random. The data were tabulated and comparison made. The results were as follows : 1. Among nurses, the analysis based on the length of experience, it is apparent that, the longer or more experience one ha s, the more complaints they have. 2 The longer the nurses are engaged in nursing practice, the more they have problems in their digestive, musculoskeletal, respiratory and nervous systems and are more prone to diseases, and get tired easier than those of shorter experience. But on the other hand it could be seen that younger nurses or nurses with less experience in the profession are more melancholic and prone to stress than those with longer experience.

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뇌졸중 후 우울증의 약침치료에 대한 중의학 임상논문 연구동향 (Trend Review of Traditional Chinese Medicine Studies on Pharmacopuncture Treatment for Post-Stroke Depression)

  • 이여경;강현진;송금주;오지연;김상범;김종민;박세진
    • 동의신경정신과학회지
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    • 제32권3호
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    • pp.235-245
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    • 2021
  • Objectives: To provide clinical evidence of pharmacopuncture treatment for post-stroke depression by reviewing randomized controlled trials on Traditional Chinese medicine pharmacopuncture for post-stroke depression. Methods: Randomized controlled trials on pharmacopuncture treatment for post-stroke depression were searched from the China National Knowledge Infrastructure (CNKI). Literature searches of English and Chinese databases were performed. Selected literature was assessed with the Jadad scale. Results: Twelve papers were selected from 20 studies. The following results were obtained: 1) Pharmacopuncture was used for post-stroke depression; 2) Dengzhan-Xixin was the most used injection medicine for post-stroke depression; 3) BaiHui (GV20) was the most used in pharmacopuncture treatment; 4) Based on the Hamilton Depression Rating Scale (HAMD), it was confirmed that all studies using pharmacopunture had significant efficacy. Conclusions: For the treatment of post-stroke depression, Dengzhans-Xixin was commonly used as an injectable medication. Additional research studies on pharmacopuncture including its practical use are needed.

의료기관 특성에 따른 간호등급 변화 추이: 2008~2010년 (Changing Trend in Grade of Nursing Management Fee by Hospital Characteristics: 2008-2010)

  • 김윤미;김지윤;전경자;함은옥
    • 임상간호연구
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    • 제16권3호
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    • pp.99-109
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    • 2010
  • Purpose: This study was aimed to examine changes of hospital nurse staffing by hospital characteristics during 2008-2010. Methods: The study sample included 44 tertiary hospitals, 226 general hospitals, and 532 non-general hospitals that were operating during 2008-2010. Grade of nursing management fee was categorized from Grade 1(highest) to 6 (lowest) in tertiary hospitals, l or Grade 7 in general hospitals and non-general hospitals based on the nurse-to-bed ratio. For data analysis, ${\chi}^2$ and GEE were conducted. Results: For three years, the number of tertiary hospitals below Grade 2 were increased from 8 to 12, the number of those above Grade 4 were decreased from 15 to 6. The number of general hospitals above Grade 6 decreased from 123 to 86. Tertiary hospitals and general hospitals had more possibilities to improve nurse staffing grade than general hospital (OR 79.69, 95% CI 50.77~125.09, OR 11.25, 95% CI 8.15~15.53, respectively). Greater likelihood of improvement in grade of nursing management fee was found in university hospital or hospitals with 300 or more beds than other types of hospitals. Conclusion: Differentiating nurse staffing system by hospital type and increasing financial incentives according to the grades are needed to improve hospital nurse staffing.

한방 성형과 매선 침법의 문헌적 고찰 및 최근 동향 (A Literature Study and Recent Tendency on Oriental Correction of Deformities and 'Needle-embedding Therapy')

  • 이은미;박동수;김도호;김현욱;조은희;안민섭;이건목
    • Journal of Acupuncture Research
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    • 제25권3호
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    • pp.229-236
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    • 2008
  • 'Needle-embedding therapy', also called 'Acupoint Embedding Therapy' is the newly induced therapy which uses specialized tools. Embedded alien substance stimulates the acupoint and helps to keep the stimulation up. Needle-embedding therapy is mainly used for chronic diseases and deficiency syndromes, and also for other diseases including acute pain and excessive syndromes. Recently, clinical doctors are studying this therapy vigorously on the foundation of 'theory of meridian pathway' and applying for facial and body esthetics such as face-lift, correction skin troubles, depilation and so on. In spite of all these effect, theories for 'Needle-embedding Therapy' doesn't seem clearly arranged yet. So we, here, present the philological basis of 'Needle-embedding Therapy' from referring to old records and newly publicated papers and consider the new trend of this therapy in Korean and China.

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Prevalence and risk factors of low back and pelvic pain in women with rectus abdominis diastasis: a multicenter retrospective cohort study

  • Yuan, Sue;Wang, Honghong;Zhou, Jie
    • The Korean Journal of Pain
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    • 제35권1호
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    • pp.86-96
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    • 2022
  • Background: To explore the association between low back pain (LBP) and pelvic pain (PP) and rectus abdominis diastasis (RAD) in postpartum women and identify the characteristics and risk factors. Methods: Women diagnosed with RAD and a history of labor and delivery, between 2009 and 2018, were identified from six hospitals within the Partners Healthcare System. Univariate and multivariable binary logistic regression analyses were used to identify the risk factors associated with pain. Results: Age at onset of RAD in the non-cesarean delivery group was earlier than those in cesarean delivery (CD) group (P = 0.017). Women who underwent CD demonstrated 4.5 times greater risk of RAD than those who had no CD exposure. The cumulative composition ratio of LBP at every age stage of the period from 8 years pre-first delivery to 8 years post-first delivery was significantly higher than the other five conditions (RAD, umbilical hernia, PP, depressive disorder [DD], and strain of muscle, fascia, and tendon [SMFT]) (P for trend < 0.001). Women with DD, SMFT, and PP were more likely to have LBP (odds ratio [OR] = 1.91, 95% confidence interval [CI] 1.06 to 3.47, P = 0.032; OR = 4.50, 95% CI 1.64 to 12.36, P = 0.003; OR = 2.14, 95% CI 1.17 to 3.89, P = 0.013; respectively). Conclusions: In postpartum women with RAD, DD, SMFT, and PP were found to be risk factors contributing to the development of LBP. Race and LBP also played roles in the development of PP.

갑상선암에 대한 고주파 절제 적용의 과거, 현재, 그리고 미래 (Application of Radiofrequency Ablation to Thyroid Cancer: Past, Present, and Future)

  • 김지훈
    • 대한영상의학회지
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    • 제84권5호
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    • pp.999-1008
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    • 2023
  • 발생률이 높고, 예후는 좋지만 재발을 잘하는 경향이 있는 갑상선암에서도 전통적인 치료법은 수술이다. 하지만, 2000년대 초반부터, 간암, 폐암, 신장암에서와 마찬가지로 고주파 절제술이 원발 갑상선암 및 재발 갑상선암에 적용되기 시작했다. 원발암에서는 1 cm 이하 크기의 미세유두암 저위험군에서 수술 불가능한 경우에 대한 많은 연구가 이뤄져 왔고, 1 cm보다 더 크고 4 cm 이하의 다양한 군에 대해서도 일부 연구가 시행되었으며, 전반적으로 모두 양호한 결과를 보고하였다. 재발암에 대해서도 주로는 국소 경부 재발암에 고주파 절제술이 시행되었으며, 일부 폐, 뼈 등의 원격 전이에 대해서도 시도되었고, 전반적으로 양호한 결과가 보고되었다. 최근 들어, 한국, 미국, 유럽 등 각지에서 갑상선암의 고주파 절제술에 대해 옹호하는 움직임이 있다. 하지만, 미국 국립 종합 암 네트워크(National Comprehensive Cancer Network) 등의 중립적인 임상지침에는 고주파 절제술이 아직 인정되지는 않은 상태이다. 지금까지의 노력들과 미래의 연구를 바탕으로 향후 가까운 미래에 갑상선암의 치료에 있어 고주파 절제술이 적절한 자리매김을 할 것으로 전망한다.

대전광역시와 충청남도의 13년간(2000-2012) 대장암 발생 추세 (Trends in Colorectal Cancer Incidence in Daejeon and Chungcheongnam-do, South Korea (2000-2012))

  • 김순영;권인선;김정아;이태용;남해성
    • 농촌의학ㆍ지역보건
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    • 제40권3호
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    • pp.115-125
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    • 2015
  • 대장암 발생에 관한 국내 역학연구는 매우 부족한 상황으로 국가단위 대장암 발생률의 추세는 보고되어 왔지만 광역 지역에서의 추세 연구는 미흡한 실정이다. 본 연구에서는 대전과 충남의 대장암 발생률 추세를 결장암과 직장암으로 구분하여 기술하고자 한다. 2000-2012년도 기간 동안 해당 지역암등록 자료를 이용하여 세계표준인구를 기준으로 연령표준화 대장암 발생률을 산출하였다. 발생률 추세는 Joinpoint Regression Program으로 분석하여 연평균 변화율(Average Annual Percent Change, AAPC)로 나타내었다. 연구 대상 암등록자료의 질적 수준 평가에서 충실도 지표(MI%)와 타당도 지표(DCO%, MV%, PSU%, AUK%)는 암 발생률의 추세를 기술하기에 전반적으로 적정한 수준이었다. 13년 동안 연령표준화 대장암 발생률은 남성과 여성 모두 지속적으로 증가하였다. 대전지역에서 남성의 경우 2000년 10만 명당 37.2건에서 2012년 51.7건으로 연평균 3.9%(AAPC) 증가하였고, 여성의 경우 2000년 10만 명당 17.1건에서 2012년 28.4건으로 연평균 3.9% 증가하였다. 충남지역에서 남성의 경우 2000년 10만 명당 29.8건에서 2012년 50.1건으로 연평균 5.1% 증가 하였고, 여성의 경우 2000년 10만 명당 15.9건에서 2012년 26.6건으로 연평균 3.2% 증가하였다. 이를 결장암과 직장암으로 분류하여 살펴보면 남녀 모두 결장암의 증가 추세가 직장암 증가보다 더 컸고, 직장암의 증가는 남성이 여성보다 더 빠른 추세였다. 결론적으로 대전과 충남의 대장암 발생은 2000년 이후 13년간 빠른 증가추세를 보였다. 이를 억제하기 위한 대장암 발생 감시와 예방에 지역사회의 관심을 더 높일 필요가 있다.

Antibody response to COVID-19 vaccination in patients on chronic hemodialysis

  • Heejung Choi;Sungdam Han;Ji Su Kim;Bumhee Park;Min-Jeong Lee;Gyu-Tae Shin;Heungsoo Kim;Kyongmin Kim;A-Young Park;Ho-Joon Shin;Inwhee Park
    • Clinical and Experimental Vaccine Research
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    • 제12권3호
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    • pp.249-259
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    • 2023
  • Purpose: Since patients on hemodialysis (HD) are known to be vulnerable to coronavirus disease 2019 (COVID-19), many studies were conducted regarding the effectiveness of the COVID-19 vaccine in HD patients in Western countries. Here, we assessed antibody response of HD patients for 6 months post-vaccination to identify the duration and effectiveness of the COVID-19 vaccine in the Asian population. Materials and Methods: We compared antibody response of the COVID-19 vaccine in HD patients with healthy volunteers. Patient and control groups had two doses of ChAdOx1 nCoV-19 and mRNA-1273, respectively. Immunoglobulin G (IgG) was measured before vaccination, 2 weeks after the first dose, 2 and 4 weeks, 3 and 6 months after the second dose. Neutralizing antibody was measured before vaccination and at 2 weeks, 3 and 6 months after second dose. Since the third dose was started in the middle of the study, we analyzed the effect of the third dose as well. Results: Although antibody production was weaker than the control group (n=22), the patient group (n=39) showed an increase in IgG and neutralizing antibody after two doses. And, 21/39 patients and 14/22 participants had a third dose (BNT162b2 or mRNA-1273 in the patient group, mRNA-1273 in the control group), and it did not affect antibody response in both group. Trend analysis showed IgG and neutralizing antibody did not decrease over time. Age, sex, and HD vintage did not affect antibody production in HD patients. Patients with higher body mass index displayed better seroresponse, while those on immunosuppressants showed poor seroresponse. Conclusion: Two doses of vaccination led to significant antibody response in HD patients, and the antibody did not wane until 6 months.

주의력결핍 과잉행동장애 아동에서 Osmotic-Controlled Release Oral Delivery System Methylphenidate의 치료순응도 (Treatment Adherence of Osmotic-Controlled Release Oral Delivery System Methylphenidate in Korean Children and Adolescents with Attention-Deficit Hyperactivity Disorder)

  • 김봉석;이정섭;김의정;성형모;신윤미;황성혜;유한익
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제25권2호
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    • pp.65-72
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    • 2014
  • Objectives : The objective of this study was to evaluate the treatment duration and adherence of osmotic-controlled release oral delivery system (OROS) methylphenidate for treatment of attention-deficit hyperactivity disorder (ADHD). Methods : A total of 843 children with ADHD were recruited : 213 children (25.3%) who had previously taken medications for ADHD and 630 drug-na$\ddot{i}$ve children (74.7%) were recruited. The dosage was adjusted according to the clinician's judgment. The primary efficacy endpoint of this study was treatment retention rate, which was estimated at Week 12 and Week 20 using the Kaplan-Meier curve. The Swanson, Nolan and Pelham-IV (SNAP-IV), Clinical Global Impression-Severity (CGI-S), Clinical Global Impression-Improvement, and the side effect rating scale were measured at every visit. Remission rates were presented based on SNAP-IV and CGI-S, respectively. Results : The treatment retention rate at 12 weeks and at 20 weeks was 76.2% and 66.8%, respectively. Divided according to 6-8, 9-11, 12-14 and 15-18 years of age, younger children tended to show a statistically higher treatment retention rate (p=.02). Based on SNAP-IV and CGI scores, children with better response to medication showed tendencies of statistically higher treatment retention rate. The most common adverse events included loss of appetite (7.1%) and insomnia (3.3%). There was no serious adverse event related to the treatment, such as death. Conclusion : The use of OROS methylphenidate for treatment of ADHD was safe and tolerable for children. In this study, lower age and better treatment response showed a statistically significant relationship with higher treatment adherence. Boys showed a trend of high treatment adherence. The treatment adherence at 20 weeks was satisfactory, however, the treatment adherence after 20 weeks showed a sharp decrease. Therefore, treatment persistence for six months after the beginning of ADHD treatment is important. In addition, the positive role of psycho-education for children and parents is necessary for increasing treatment adherence.

신경계 질환에서 근적외선분광분석법의 적용: 기립불내증을 중심으로 (Application of Near-Infrared Spectroscopy in Neurological Disorders: Especially in Orthostatic Intolerance)

  • 김유환;백승호;;석흥열;전남준;김법민;김병조
    • 대한신경과학회지
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    • 제35권1호
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    • pp.8-15
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    • 2017
  • Near-infrared spectroscopy (NIRS), a noninvasive optical method, utilizes the characteristic absorption spectra of hemoglobin in the near-infrared range to provide information on cerebral hemodynamic changes in various clinical situations. NIRS monitoring have been used mainly to detect reduced perfusion of the brain during orthostatic stress for three common forms of orthostatic intolerance (OI); orthostatic hypotension, neurally mediated syncope, and postural orthostatic tachycardia syndrome. Autonomic function testing is an important diagnostic test to assess their autonomic nervous systems for patients with symptom of OI. However, these techniques cannot measure dynamic changes in cerebral blood flow. There are many experimentations about study of NIRS to reveal the pathophysiology of patients with OI. Research using NIRS in other neurologic diseases (stroke, epilepsy and migraine) are ongoing. NIRS have been experimentally used in all stages of stroke and may complement the established diagnostic and monitoring tools. NIRS also provide pathophysiological approach during rehabilitation and secondary prevention of stroke. The hemodynamic response to seizure has long been a topic for discussion in association with the neuronal damage resulting from convulsion. One critical issue when unpredictable events are to be detected is how continuous NIRS data are analyzed. Besides, NIRS studies targeting pathophysiological aspects of migraine may contribute to a deeper understanding of mechanisms relating to aura of migraine. NIRS monitoring may play an important role to trend regional hemodynamic distribution of flow in real time and also highlights the pathophysiology and management of not only patients with OI symptoms but also those with various neurologic diseases.