Lim, Bora;Lee, Hee Jung;Kim, Min Chul;Kim, Byung Joo
Journal of Pharmacopuncture
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v.16
no.2
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pp.55-61
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2013
Objective: Ulmi Pumilae Cortex (UPC) is a deciduous tree with uneven pinnate leaves and is classified as a subfamily of Ulmuceae and contains many pharmacologically active constituents. The aim of this study was to investigate the effects of UPC on the growth and survival of AGS cells, the most common human gastric adenocarcinoma cell lines. Methods: The AGS cells were treated with varying concentrations of UPC. Analyses of the sub G1, caspase-3 activity, and mitochondrial depolarization were conducted to determine whether AGS cell death occured by apoptosis. Furthermore, to identify the role of the transient receptor potential melastatin (TRPM) 7 channels in AGS cell growth and survival, we used human embryonic kidney (HEK) 293 cells overexpressed with TRPM7 channels. Results: The addition of UPC to a culture medium inhibited AGS cell growth and survival. Experimental results showed that the sub G1, caspase-3 activity, and mitochondrial depolarization were increased. Furthermore, TRPM7 channel overexpression in HEK 293 cells exacerbated UPC-induced cell death. Conclusion: These findings indicate that UPC inhibits the growth and survival of gastric cancer cells due to a blockade of the TRPM7 channel activity. Therefore, UPC is a potential drug for treatment of gastric cancer, and TRPM7 channels may play an important role in survival in cases of gastric cancer.
Buddhism that has arisen in India began to build the Stupa to enshrine body and Sari of Buddha as an object of worship. The stupa existed as a tome of holy leaders even before the birth of Buddha, which was called stupa or tupa in the Sanskrit and the Pali, the ancient language of India. The stupa was renamed accordingly in each Buddhism transmitted countries such as Ceylon, Tibet, Nepal, Myanmar, Thailand and China and also reshaped according to their own formative style. But its original meaning and type are kept unchanged. The stupa was established in the 4 holy places including the birth place of Buddha, the place where Buddha found enlightenment, the place where Buddha preached for the first time, and the place where Buddha died. Thus, a pagoda to commemorate holy ancient places is called Chaitya, which became differentiated from the stupa in which Sari is enshrined. The stupa means Nirvana, the eternal body of Buddha, and also a place filled with teaching and preaching of Buddhism. It signifies the symbol of Buddha who escaped from the death and rebirth, to achieve complete extinction, i.e. parinirvana, and to reach ultimate eternal world, rather than simply means death. During the non-statue of th Buddha period, people built the stupa to embody Nirvana of the Buddha, and worshipped the tomb where body of holy saints was enshrined. On the other hand, they also sanctified memorial things such as tools that holy saints used, the Bo tree under which one achieved Nirvana, Dharma cakra that implied words, footprint that carried out mission work, and a way to reach to heaven.
No, Sun-Ho;Baek, Chung-Youl;You, Young-Han;Cho, Sam-Rae
Journal of Ecology and Environment
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v.38
no.4
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pp.415-424
/
2015
This research was conducted to reveal the characteristics of breeding ecology of oriental scops owl (Otus sunia stictonotus) inhabiting in South Korea according to the nest types during the breeding season from march to October for two years (2011 and 2012). Oriental scops owl nested in woodpecker's nest holes (46.1%), natural tree holes (38.5%), and artificial wood boxes (15.4%). These nests were located on following trees: Zelkova serrata, Paulownia coreana, Celtis sinensis, Salix chaenomeloides, Salix babylonica, Fraxinus rhynchophylla, Robinia pseudoacacia and Platanus occidentalis. The hatching success was 91.4%, fledging success was 83.0%, and breeding success was 75.9%. The factors of the breeding failure were falling (57.1%), abandonment (28.6%), hatching failure (7.1%), and others with unknown cause of death (7.1%). According to nest types, the fledging success (69.2%) of woodpecker's nest holes were low and the hatching success (79.2%) of natural tree holes were also low due to hatching failure and abandonment. However, hatching success, fledging success, breeding success were high in the artificial nests as all the eggs hatched and succeeded in fledging. Therefore, we suggested that artificial nests can cover the weaknesses of natural nests as well as increasing the breeding success. However, long-term research on installation place, height, and hole sizes of the artificial nest are required in order to clearly reveal the effects on the breeding success of oriental scops owl.
These days, most of safety-critical systems, which are systems those failures or malfunction may result in death or serious injury to people, or loss or severe damage to social systems, or environmental harm, are being built of embedded software or loaded controlling software systems on computers, electrical and electronic components or devices. There are a lot kind of fault analysis methods to evaluate safety of the safety-critical systems equipped computers, electrical and electronic components or devices with software. However, the only assessment method to evaluate software safety of a safety-critical system is not enough to analysis properly on account of the various types and characteristic of software systems by progress of information technology. Therefore, this paper proposes the integrated evaluation method and carries out a case study for the software safety of safety-critical system which embedded or loaded software sizes are small and control response times are not sensitive by use of two security analysis methods which are Fault Tree Analysis (FTA) and Fault Modes and Effect Analysis (FMEA) for ubiquitous healthcare system.
The growth conditions of planted trees, invasion of nuisance herbaceous species, competition between species, and effects of erosion control were monitored over five years in a riparian greenspace in Gapyeong County that was established through multilayered and grouped ecological planting. Of 156 trees planted in the upper and middle layers, 5.8% died. This tree death was attributed to poor drainage or aeration in the rooting zone from the clay-added root ball and too deep planting as well as a small-sized root ball and scanty fine roots. Of all the trees, 21.6% grew poorly due to transplant stress in the first year after planting, but they started to grow vigorously in the third year. This good growth was largely associated with soil improvement before planting, selection of appropriate tree species based on growth ground, and control of dryness and invasive climbing plants through surface mulching and multilayered/grouped planting. Mixed planting of fast-growing species as temporary trees was desirable for accelerating planting effect and increasing planting density. Thinning of fast-growing trees was required in the fifth year after planting to avoid considerable competition with target species. To reduce the invasion of herbaceous and climbing plants that oppress normal growth of planted trees, higher density planting of trees (crown opening of about 15%), woodchip mulching to a 10-cm depth, and edge planting 2 m wide were more effective than lower density planting (crown opening of 70%), no surface mulching, and no edge planting, respectively. This reduction effect was especially great during the first three years after planting. Nuisance herbaceous plants rarely invaded higher density planting with woodchip mulching over the five years. Higher density planting or woodchip mulching also showed much greater erosion control through rainfall interception and buffering than lower density planting with no mulching did. Based on these results, desirable planting and management strategies are suggested to improve the functions of riparian greenspaces.
From February 1988 to December 1990, 42 patients underwent so called REV operation for pulmonary stenosis or atresia with or without anomalies of ventriculoarterial connection and truncus arteriosus. The principles of operative technique are mobilization of pulmonary arterial tree beyond the pericardial reflection, transection of pulmonary trunk between the pulmonary ventricle and pulmonary artery, suture of distal pulmonary arterial stump to the upper margin of Pulmonary ventriculotomy site with absorbable suture, and anterior patch with 0.625% glutaraldehyde fixed autologous pericardium with monocusp inside it. Age at operation ranged 3-156months [mean 41.8 month] with twelve of whom infants. Operative indications were pulmonary atresia, with ventricular septal defect[16], and pulmonary stenosis with double outlet right ventricle[8], with ventricular septal defect[16], with double outlet right ventricle[8], with complete transposition of the great arteries[8], with corrected transposition of the great arteries[6], with Fallot`s tetralogy[3], and truncus arteriosus[1]. There were six hospital deaths[14%] and no late death. Twenty-four of 36 survivals were followed up more than 12 months with good clinical results. Postoperative angiocardiogram was performed in fifteen patients. Hemodynamically, two patents had residual pressure gradients along the pulmonary outflow tract, one patient showed severe pulmonary regurgitation; morphologically, there were six significant stenosis of left pulmonary arterial tree, two of whom showed significant pressure gradients. Our present experience with REV operation suggests that this technique make it possible to perform anatomic repair in a wide variety of congenital anomalies of abnormal ventriculoarterial connection associated with pulmonary outflow tract obstruction without using the prosthetic material, even in infants, with relatively low mortality and morbidity.
Relapsing polychondritis (RP) is a rare inflammatory disorder of unknown etiology, causing recurrent inflammatory and degenerative reactions involving the cartilaginous structures throughout the body. Generally, RP is known as multiorgan disease presented as auricular chondritis, arthritis, nasal chondritis, ocular inflammation, audiovestibular damage and respiratory tract inflammation. Major airway involvement occurs in more than 50% of the patient and has been reported to be the primary cause of death. Rarely, it may be presented with only respiratory symptoms without typical clinical manifestation of RP. We experienced a 64-year-old male patient with RP involving diffuse airway tract without other characteristic clinical manifestation and present here with a review of literatures.
Journal of the Korea Institute of Information and Communication Engineering
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v.21
no.8
/
pp.1560-1566
/
2017
Recently, accumulation of data on pig farm is enabled through the wide spread of smart pig farm equipped with Internet-of-Things based sensors, and various machine learning algorithms are applied on the data in order to improve the productivity of pig farm. Herein, multiple machine learning schemes are used to predict the water usage in pig farm which is known to be one of the most important element in pig farm management. Especially, regression algorithms, which are linear regression, regression tree and AdaBoost regression, and classification algorithms which are logistic classification, decision tree and support vector machine, are applied to derive a prediction scheme which forecast the water usage based on the temperature and humidity of pig farm. Through performance evaluation, we find that the water usage can be predicted with high accuracy. The proposed scheme can be used to detect the malfunction of water system which prevents the death of pigs and reduces the loss of pig farm.
Mi Na Choi;Do-Hun Lee;Moon-Jeong Jang;Dong Ju Kim;Sun Mi Lee;Yoon Jung Moon;Yong Sung Kwon
Korean Journal of Environmental Biology
/
v.41
no.1
/
pp.18-30
/
2023
Forest destruction is an inevitable result of the development processes. According to the environmental impact assessment, over 10% of the destroyed trees need to be recycled and transplanted to minimize the impact of forest destruction. However, the rate of successful transplantation is low, leading to a high rate of tree death. This is attributable to a lack of consideration for environmental factors when choosing a temporary site for transplantation and inadequate management. To monitor transplanted trees, a field survey is essential; however, the spatio-temporal aspect is limited. This study evaluated the applicability of remote sensing for the effective monitoring of transplanted trees. Vegetation indices based on satellite remote sensing were derived to detect time-series changes in the status of the transplanted trees at three temporary transplantation sites. The mortality rate and vitality of transplanted trees before and after the transplant have a similar tendency to the changes in the vegetation indicators. The findings of this study showed that vegetation indices increased after transplantation of trees and decreased as the death rate increased and vitality decreased over time. This study presents a method for assessing newly transplanted trees using satellite images. The approach of utilizing satellite photos and the vegetation index is expected to detect changes in trees that have been transplanted across the country and help to manage tree transplantation for the environmental impact assessment.
Journal of the Korean Institute of Traditional Landscape Architecture
/
v.39
no.3
/
pp.42-55
/
2021
This study investigated the memories of the natives and the migrants who had been living with the 760-year-old Zelkova serrata located in the Keangnam Apartment Complex in Dogok 1-dong. Place memory is a newly illuminated concept since the 1980s, and is also used as a new research methodology for studying and recording multi-layered memories left in a place based on feelings and traces of vivid memories. The urban development of Gangnam, which began in the 1970s, quickly changed rural to apartment complexes. The natives of Yeokmal were scattered throughout the country, and new migrants moved in. In the process, zelkova serrata was managed in different ways from time to time, and residents also establish relationship in different ways. Natives used to take a rest in the tree or swing at Dan-o, and recognized it as a place to receive the god during the village ritual. In other words, they shared the entire process of life and death and were given various roles depending on the lives of the residents. It is also a direct experience that was experienced in detail and a place where collective memories of residents are melted. On the other hand, with the construction of Keangnam Apartment, the management of zelkova tree has become stricter, making it impossible for migrants to access. Migrants have come to enjoy zelkova serrata visually, and the annual Yeokmal Traditional Festival makes common memories in the city. In addition, many people personified trees and received mental comfort. In addition, the nature of the old big tree was highlighted in the background of the city, and the symbol of "uniqueness and speciality" was newly formed, which led to the formation of pride and attachment. Through the memories of the two subjects' zelkova tree, we were able to examine the memories of the tree value, and management of protected tree in the city.
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