• Clean Technology
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• v.19 no.4
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• pp.355-369
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• 2013

Economic feasibility is one of the most important factors in energy production from regenerative biomass. From the aspect, biogas from anaerobic digestion of wastewater sludge is regarded as the most economical because of its cheap substrate and additional income from the disposal of waste sludge. Sludge hydrolysis has been regarded as the rate limiting step of anaerobic digestion and many sludge pre-treatment technologies have been developed to accelerate anaerobic sludge digestion for enhanced biogas production. Various sludge pre-treatment technologies including biological, thermo hydrolysis, ultrasonic, and mechanical methods have been applied to full-scale systems. Sludge pre-treatment increased the efficiency of anaerobic digestion by enhancing hydrolysis, reducing residual soilds, and increasing biogas production. This paper introduces the characteristics of various sludge pre-treatment technologies and the energy balance and economic feasibility of each technology were compared to prepare a guideline for the selection of feasible pre-treatment technology. It was estimated that thermophilic digestion and thermal hydrolysis were most economical technology followed by Cell rupture$^{TM}$, OpenCEL$^{TM}$, MicroSludge$^{TM}$, and ultrasound. The cost for waste sludge disposal shares the biggest portion in the economic analysis, therefore, water content of the waste sludge was the most important factor to be controlled.

• 수도
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• v.24 no.5 s.86
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• pp.16-28
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• 1997

As sewerage works has become one of the major public works in Korea, the employment of advanced and more appropriate sewerage technology has become essential to improve the efficiency of sewerage works. During last 10 years, the Korean Government has made tremendous amount of investment on sewerage works so that treatment plants in 58 cities have treatment capacity which is equivalent to 52.8% of total daily sewage generation in Korea. This remarkable development, however, has heavily depended on one technology, the conventional activated sludge process as more than 95% of the existing plants employ this process, Recently, the Korean Government and local authorities have plans to introduce more appropriate sewage treatment technologies and research and development in this area has become very active. To encourage employing new and appropriate technologies, however, the proper technology evaluation and verification program for new process is needed. The public sector should play a key role in this program since the sewerage works is one of the major public works. In this paper, the technology evaluation and verification programs related with sewerage facilities in the US and Japan are briefly reviewed. The Innovatived and Alternative Technology programs which was operated by US EPA until recently and Environmental Technology Verification(ETV) program which was commenced in 1995 are introduced. The technology verification programs operated in Japan and also in Korea are also reviewed in this paper to propose a future direction for development of the appropriate evaluation and verification system.

• Membrane and Water Treatment
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• v.9 no.2
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• pp.87-94
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• 2018

The interactions of water soluble polymers with dye are studied by ultrafiltration using a molecular weight cut off of 10 KDa regenerated cellulose ultrafiltration membrane. Two water-soluble polymers, namely Poly (Sodium-4 Styrenesulfonate) (PSS) and Poly (Vinyl Alcohol) (PVA) were selected for this study. The effects of process parameters, such as, polyelectrolyte concentrations, transmembrane pressure, ionic strength and pH of solution on dye retention and permeation flux were examined. PSS enhanced ultrafiltration achieved dye retention as high as 99% as a result of complexation between polyanion containing aromatic groups and cationic dye. This result was confirmed by the red shift. The retention of dye decreases as the salt concentration increases, a high retention was obtained at pH above 4. However, in case of PVA, relatively low retention (50%) was observed. Ionic strength and pH has no significant effect on the removal of MB. The permeate flux depended slightly on polyelectrolytes concentrations, transmembrane pressure, salt concentration and pH.

• Journal of Korean Neurosurgical Society
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• v.61 no.3
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• pp.376-385
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• 2018

Recent discoveries of brain tumor-related genes and fast advances in genomic testing technologies have led to the era of molecular diagnosis of brain tumor. Molecular profiling of brain tumor became the significant step in the diagnosis, the prediction of prognosis and the treatment of brain tumor. Because traditional molecular testing methods have limitations in time and cost for multiple gene tests, next-generation sequencing technologies are rapidly introduced into clinical practice. Targeted sequencing panels using these technologies have been developed for brain tumors. In this article, focused on pediatric brain tumor, key discoveries of brain tumor-related genes are reviewed and cancer panels used in the molecular profiling of brain tumor are discussed.

• Proceedings of the KSME Conference
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• 2007.05a
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• pp.1475-1480
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• 2007

In the last few years, lasers have found new applications in production engineering as tools for surface treatment, cutting, welding, drilling and marking. So far, the laser has mainly been used in special laser processing machines ('laser-only') directly integrated into a production line or serving as stand-alone stations in the workshop. By combining conventional metal cutting technologies with laser processes in one machine, complete processing of a workpiece with different technologies in one setting can be realized. The main advantages are a reduction of the material flow between the production machines, which leads to a reduction in processing time and logistics, and an enhancement of manufacturing quality due to the processing in one setting. In addition to this approach new processing technologies such as laser-assisted machining are possible.

• Proceedings of the Korean Radioactive Waste Society Conference
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• 2003.11a
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• pp.172-179
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• 2003

Various type of tritium wastes can be produced from nuclear fuel cycle process satisfying non-proliferation, CANDU reactors, and nuclear industry. Activities of tritium processing in the world were surveyed to develope the processing technologies of tritium wastes. The tritium wastes were classified into gas phase, liquid phase, and organic phase. And the treatment techniques for the tritium wastes are analyzed. Development of tritium processing technologies is essential to finding public acceptance of radioactive wastes and forming a solid foundation to foster the growth of nuclear industry in Korea.

• Molecules and Cells
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• v.41 no.8
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• pp.717-723
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• 2018

Chimeric antigen receptor (CAR) T-cell therapy, an emerging immunotherapy, has demonstrated promising clinical results in hematological malignancies including B-cell malignancies. However, accessibility to this transformative medicine is highly limited due to the complex process of manufacturing, limited options for target antigens, and insufficient anti-tumor responses against solid tumors. Advances in gene-editing technologies, such as the development of Zinc Finger Nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9), have provided novel engineering strategies to address these limitations. Development of next-generation CAR-T cells using gene-editing technologies would enhance the therapeutic potential of CAR-T cell treatment for both hematologic and solid tumors. Here we summarize the unmet medical needs of current CAR-T cell therapies and gene-editing strategies to resolve these challenges as well as safety concerns of gene-edited CAR-T therapies.

• Membrane and Water Treatment
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• v.10 no.1
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• pp.39-44
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• 2019

LID facilities do not consider environmental factors, and due to inappropriate vegetation planting causing degradation in efficiency due to plant damage and difficulty in maintenance. Therefore, in this study, assessment of impact environmental factor by seasonal variation of chlorophyll and growth of vegetation planted in LID technologies and change of pollutant reduction were conducted. In the case of B-SJ and B-RI, growth rate decreased after summer (August), and B-MG showed steady growth until autumn (September). Chlorophyll was found to increase during spring season while it decreased during autumn season. The chlorophyll concentration was found to affect the plant growth pattern. TN reduction efficiency was highest with greater than 80% efficiency in summer, and it was analyzed that plants were identified as the main factor affecting the seasonal reduction efficiency of TN. Also, temperature and relative humidity were analyzed to affect plant growth, activity and pollutant removal efficiency. Plant type and growth pattern are considered as factors to be considered in selection of appropriate plant types in LID technologies.

• Journal of the Korean Society for Marine Environment & Energy
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• v.8 no.4
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• pp.174-178
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• 2005

Destruction of marine ecology system induced by the bal last water discharged from ships is one of the most serious problem among the various ship associated environmental impacts. International Maritime Organization (IMO) has actively dealt with this problem for a long time and is going to start to activate very strong international treatment for preventing ocean from such serious environmental impact. Various technologies of ballast water treatment are now being developed all over the world. In this paper, recent trend of existing ballast water treatment technologies is investigated in detail. Furthermore, in order to apply electrolysis technology to ballast wale r treatment, its basic principle is reviewed theoretically and its feasibility is checked through some in-situ experiments. Quite good results are shown in the experiments enough to confirm its applicability in ballast water treatment.

• New & Renewable Energy
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• v.4 no.2
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• pp.21-30
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• 2008

Anaerobic digestion (AD) is the most promising method of treating and recycling of different organic wastes, such as OFMSW, household wastes, animal manure, agro-industrial wastes, industrial organic wastes and sewage sludge. During AD, i.e. degradation in the absence of oxygen, organic material is decomposed by anaerobes forming degestates such as an excellent fertilizer and biogas, a mixture of carbon dioxide and methane. AD has been one of the leading technologies that can make a large contribution to producing renewable energy and to reducing $CO_2$ and other GHG emission, it is becoming a key method for both waste treatment and recovery of a renewable fuel and other valuable co-products. A classification of the basic AD technologies for the production of biogas can be made according to the dry matter of biowaste and digestion temperature, which divide the AD process in wet and dry, mesophilic and thermophilic. The biogas produced from AD plant can be utilized as an alternative energy source, for lighting and cooking in case of small-scale, for CHP and vehicle fuel or fuel in industrials in case of large-scale. This paper provides an overview of the status of biogas production and utilization technologies.