• Title/Summary/Keyword: Treatment status

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Association between the Weight Gain and Treatment Response to Atypical Antipsychotics in Korean Patients with Schizophrenia (한국인 정신분열병 환자에서 비정형 항정신병 약물의 치료반응과 체중증가의 관련성에 대한 연구)

  • Lee, Jae-Byung;Ham, Byung-Joo;Lee, Hwa-Young;Lee, Min-Soo
    • Korean Journal of Biological Psychiatry
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    • v.18 no.4
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    • pp.225-231
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    • 2011
  • Objectives Atypical antipsychotics show better treatment efficacy, safety and tolerability than typical antipsychotics. Among the adverse events observed during treatment with antipsychotics, extrapyramidal syndrome (EPS) and negative symptoms has been greatly reduced. But still, weight gain is receiving growing attention. The aim of this study was to investigate the association between therapeutic response to atypical antipsychotics and weight gain in admission status. Methods The study was conducted for Korean inpatients with schizophrenia in a university hospital in Seoul, between Jan 2006 and Dec 2010. Data was collected by reviewing the medical record of 39 consecutively hospitalized patients with Schizophrenia (DSM-IV) at a university hospital. Positive and Negative Symptom Scale (PANSS), Body Mass Index (BMI) and body weights were measured. Results No significant difference was observed for sex, age, illness onset age, family history of schizophrenia, numbers of hospitalization before treatment, educational years, marriage status, occupational status and subtype of schizophrenia between weight gainers and non-weight gainers. Regarding treatment response to atypical antipsychotics, weight gainers show significantly more PANSS decrease than non-weight gainers during admission period. Conclusions Our findings suggest that it appears to be more likely to respond to atypical antipsychotics in weight gainers than non-weight gainers (that weght gainers appear to be more likely to respond to atypical antipsychotics than non-weight gainers). These results show that the antipsychotic-induced body weight gain is associated with therapeutic response of antipsychotics in Korean inpatients with schizophrenia.

Comparison of Wage Treatment, Employment Environment, and Job Stability before and after Conversion to Indefinite Contract Status for School Foodservice Employees in Gangwon Province (강원도 학교급식 조리종사원의 무기계약직 전환 정책에 따른 임금처우, 고용환경, 직무안정성 비교분석)

  • An, Yong-Sun;Choi, Hang-Sok;Lee, Hae-Young
    • Journal of the Korean Dietetic Association
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    • v.24 no.3
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    • pp.261-274
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    • 2018
  • The purpose of this study was to compare wage treatment and the employment environment of school foodservice employees before and after conversion to indefinite contract status since September 2012 when the Ordinance on the Appointment of Education Officials (indefinite contract) under the Gangwon Provincial Superintendent of Education was applied as well as to examine the effects of wage treatment and the employment environment on job stability. The questionnaire survey was conducted from March 31 to April 10, 2017 for school foodservice employees working at 97 schools in Gangwon province. A total of 477 questionnaires were distributed and 470 questionnaires were used for the analysis. Statistical analysis was conducted using SPSS Window Ver.18.0. The detailed results of this study were as follows. First, wage treatment (2.29 vs. 3.16), employment environment (3.45 vs. 4.22) and job stability (1.88 vs. 2.35) revealed significantly positive perceptions after conversion to indefinite contract status compared to before conversion. Second, after analyzing leading factors influencing job stability, it was revealed that wage treatment (before: ${\beta}{\hat{a}}=0.516$, P<0.05; after: ${\beta}{\hat{a}}=0.465$, P<0.05) had a positive (+) effect on job stability, whereas employment environment did not affect job stability. In conclusion, in the context that most school foodservice employees are contract employees, this study is significant in that the changes in the employment policies of the national government and education office were confirmed to have effects on school foodservice employees.

The Status and Treatment Outcomes in Patients with Hypopharyngeal Cancer: A Nationwide Population-based Study (하인두암 환자들의 발생 현황 및 치료 방법에 따른 결과 분석: 국민건강보험공단 자료를 이용한 연구)

  • Kim, Hyun-Bum;Han, Kyung-Do;Joo, Young-Hoon
    • Korean Journal of Head & Neck Oncology
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    • v.37 no.2
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    • pp.19-24
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    • 2021
  • Background/Objectives: The aim of this national population-based retrospective study was to analyze the status and treatment outcome in patients with hypopharyngeal cancer. Materials & Methods: Participants were included in the KNHIS national sample cohort who received a KNHIS health check-up in 2008 and 2009, and we followed these individuals until 2017. Patients were defined as having hypopharynx cancer if they had admissions records for hypopharynx cancer in their national health insurance data from 2010 to 2017. Results: The study cohort included 3,922 patients. According to our nationwide data, 3,533(90.1%) were male with a median age of 65.03±11.04 years at the time of diagnosis. Among parametric models for hypopharyngeal cancer prognosis, old age (Hazard ratio [HR]:1.92; 95% confidence interval[CI]:1.76-2.09), female (HR:0.77; 95% CI:0.66-0.89), and low socioeconomic status (HR:1.216; 95% CI:1.114-1.327) were significantly associated with survival. Compared with concurrent chemoradiotherapy, patients who received no treatment (HR, 1.88; 95% CI, 1.31-2.70), neoadjuvant chemotherapy followed by surgery (HR, 1.21; 95% CI, 1.04-1.41), and chemotherapy alone (HR, 1.16; 95% CI, 1.03-1.27) showed poor prognosis in hypopharyngeal cancer. Conclusion: Our data indicated that age, sex, and income were significant predictors of lifetime survival in patients with hypopharyngeal cancer. Treatment modalities were also associated with prognosis. The data have implications for treatment investigations and prevention strategies.

Enhanced sewage effluent treatment with oxidation and adsorption technologies for micropollutant control: current status and implications (미량오염물질 관리를 위한 산화 및 흡착 기반 하수 방류수 강화처리 기술의 연구 동향 및 시사점)

  • Choi, Sangki;Lee, Woongbae;Kim, Young Mo;Hong, Seok Won;Son, Heejong;Lee, Yunho
    • Journal of Korean Society of Water and Wastewater
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    • v.36 no.2
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    • pp.59-79
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    • 2022
  • Conventional wastewater treatment plants (WWTPs) do not fully remove micropollutants. Enhanced treatment of sewage effluents is being considered or implemented in some countries to minimize the discharge of problematic micropollutants from WWTPs. Representative enhanced sewage treatment technologies for micropollutant removal were reviewed, including their current status of research and development. Advanced oxidation processes (AOPs) such as ozonation and UV/H2O2 and adsorption processes using powdered (PAC) and granular activated carbon (GAC) were mainly discussed with focusing on process principles for the micropollutant removal, effect of process operation and water matrix factors, and technical and economic feasibility. Pilot- and full-scale studies have shown that ozonation, PAC, and GAC can achieve significant elimination of various micropollutants at economically feasible costs(0.16-0.29 €/m3). Considering the current status of domestic WWTPs, ozonation and PAC were found to be the most feasible options for the enhanced sewage effluent treatment. Although ozonation and PAC are all mature technologies, a range of technical aspects should be considered for their successful application, such as energy consumption, CO2 emission, byproduct or waste generation, and ease of system construction/operation/maintenance. More feasibility studies considering domestic wastewater characteristics and WWTP conditions are required to apply ozonation or PAC/GAC adsorption process to enhance sewage effluent treatment in Korea.

Health Welfare Service Needs Analysis Using a Functional Status Assessment Instrument (기능상태 평가도구를 이용한 일 농촌지역 노인의 보건복지 서비스 요구분석)

  • Choi, Jeong-Ae
    • Journal of Korean Academy of Rural Health Nursing
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    • v.2 no.1
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    • pp.60-69
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    • 2007
  • Objectives: This study was done to identify health and functional status of rural elders, to identify the use of health and medical treatment and welfare services in order to present directions for improving use of health and welfare services by rural elders. Methods: The participants in the study were 170 elders over 65 years of age who live in the one of the 6 villages served by the Young Am Community Health Post. The elders were visited at home and interviewed the elders using the RAI tool. Descriptive statistics including frequency and range were used to analyze the data. Results: Limitations in physical function, finances and medical treatment service were identified. Conclusions: The findings of this study indicate a need to develop good quality service which is affordable and convenient.

Effect of Simulated Acid Rain on Water Status and Growth of Glycine soja S. et. Z. (인공산성비가 돌콩의 생육과 잎의 수분 상태에 미치는 영향)

  • 윤의수
    • Korean Journal of Plant Resources
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    • v.13 no.2
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    • pp.131-139
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    • 2000
  • The effects of the simulated acid rain on the growth response and water status of Glycine soja was observed in 2 months-old seedlings. The seedlings were treated with acid rain(pH 3.5), three times per week. Glycine soja showed significant reduction in the total length, total weight, dry weight, water contents and top/root ratio after treatment of simulated acid rain(pH 3.5) for 56 days. The growth of shoot was more susceptible to acid rain than that of roots. On the contray, Number of lateral roots, water saturation deficit and epidermis transpiration was higher than that of control(pH 5.6) after 56 days treatment of simulated acid rain.

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A Study on Cancer Patients' Quality of Life, Perceived Health Status and Susceptibility.Severity for Cancer Recurrence (암환자의 삶의 질, 지각된 건강상태 및 암재발 인지에 관한 연구)

  • Shin, Im-Sik;Han, Sang-Sook
    • Journal of East-West Nursing Research
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    • v.11 no.2
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    • pp.146-154
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    • 2005
  • Purpose: This study was designed to identify the relationship between quality of life, perceived health status, perceived susceptibility severity to recurrence of cancer and character of object in cancer patients to provide the basic data of effective nursing interventions. Method: The subject of this study was randomly chosen from the patients diagnosed of cancer and being hospitalised or receiving chemotherapy as outpatients, at a Division of Hemato-Oncology, Department of Internal Medicine of a university hospital located in Seoul. The tool used in this study was a measurement tool for quality of life (${\alpha}=.829$), perceived health status (${\alpha}=.903$), and perceived susceptibility and severity for cancer recurrence (${\alpha}=.860$). The collected data were analysed using SPSS PC 12.0 Programme for real number, percentage, average, standard deviation, Pearson's Correlation, t-test and ANOVA, according to the purpose of this study. Result: 1) The score of quality of life in cancer patients was 3.64 point, perceived health status was 2.62 and perceived susceptibility severity to recurrence of cancer was 2.41. 2) There was a significant difference in the quality of life according to general characteristics, such as level of education, occupation, level of activity, pain, medication period, diagnosis, disease stage, purpose of medication, and recurrence. There was a significant difference in perceived health status according to age, level of activity, pain, diagnosis, purpose of medication, and recurrence. There was a significant difference in perceived susceptibility severity to recurrence of cancer according to age, level of education, and pain. 3) The cancer patients' quality of life showed significant correlation with perceived health status, perceived susceptibility severity to recurrence of cancer, pain, job, treatment purpose, relapse. The perceived health status showed significant correlation with perceived susceptibility severity to recurrence of cancer, pain, treatment purpose, relapse. The perceived susceptibility severity to recurrence of cancer showed significant correlation with pain. The relapse showed significant correlation with treatment purpose. The cancer patients' quality of life, perceived health status, and perceived susceptibility and severity for cancer recurrence, as confirmed above, showed differences according to the related factors of each subject, and it was also confirmed that those factors were significantly related with general characteristics. Upon these results, I suggest further studies on the factors that affect the cancer patients' quality of life.

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Distribution of Periodontal Status and Treatment Need between Smoker and Nonsmoker (흡연자와 비흡연자의 치주상태 및 치주치료요구도 - 일부 대학생 흡연자 중심 -)

  • Cho, Myung-Sook;Kim, Young-Sun;Jeong, Hyun-Ja
    • Journal of Korean society of Dental Hygiene
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    • v.1 no.1
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    • pp.111-123
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    • 2001
  • Objectives : The purpose of this study was to investigate distribution of periodontal status and treatment need between smokers and nonsmokers. Methods : Interview and measurement was completed by 82 smoker students and 59 nonsmoker students in Taegu Health College from April 1 to 31, 2001. The community periodontal index of treatment needs(CPITN) was analyzed by percentage. Results : In distribution of CPITN by age, almost all subjects had periodontal diseases except for aged 20~24 years nonsmokers(4%). Smoking 5 cigarettes per a day, up to 10, and above 10 increased 5.3%. 7.1%. and 9.5% in 4 score of CPITN, respectively. In years of smoking, smokers who had above 5 years(13.5%) were higher than below those(6.7%), 20% for smoker who take tooth brushing once per a day had higher than 8.3%(or three in depth of pocket above 6mm. In treatment need, all subjects should take education(or oral health except for aged 20~24 years nonsmokers(4%), 96% of smokers and nonsmokers were need scaling. Conclusion : This study indicated that treatment needs for periodontal diseases and scaling in smoker were higher than nonsmoker those.

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Temporomandibular joint dislocation: experiences from Zaria, Nigeria

  • Agbara, Rowland;Fomete, Benjamin;Obiadazie, Athanasius Chukwudi;Idehen, Kelvin;Okeke, Uche
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.40 no.3
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    • pp.111-116
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    • 2014
  • Objectives: Dislocation of the temporomandibular joint may occur for various reasons. Although different invasive methods have been advocated for its treatment, this study highlights the value of non-invasive treatment options even in chronic cases in a resource-poor environment. Materials and Methods: A seven-year retrospective analysis of all patients managed for temporomandibular joint dislocation in our department was undertaken. Patient demographics, risk factors associated with temporomandibular joint dislocation and treatment modalities were retrieved from patient records. Results: In all, 26 patients were managed over a seven-year period. Males accounted for 62% of the patients, and yawning was the most frequent etiological factor. Conservative treatment methods were used successfully in 86.4% of the patients managed. Two (66.7%) of the three patients who needed surgical treatment developed complications, while only one (5.3%) patient who was managed conservatively developed complications. Conclusion: Temporomandibular joint dislocation appears to be associated with male sex, middle age, yawning, and low socio-economic status, although these observed relationships were not statistically significant. Non-invasive methods remain an effective treatment option in this environment in view of the low socio-economic status of the patients affected.

The Experts Survey and In-depth Interview on the Korean Medicine Treatments for the Cerebral Palsy Children (뇌성마비 환아 한의치료 기술에 대한 전문가 설문 및 심층 면접 연구)

  • Son, Chi Hyoung;Yun, Young Ju;Yu, Sun Ae
    • The Journal of Pediatrics of Korean Medicine
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    • v.30 no.4
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    • pp.66-76
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    • 2016
  • Objectives This study aims to investigate current status of the Korean medicine treatment on the cerebral palsy (CP) via interviewing the doctors who have expertise in CP children. Methods From June 2015 to May 2016, the surveys and in-depth interviews were conducted on the fifteen Korean medicine doctors. Results Based on the surveys and interviews, widely-used treatments were body acupuncture and herbal decoction. Scalp acupuncture, intradermal acupuncture and manipulation were also used frequently. Experts stated Korean medicine could be more effective in younger patients, patients with cognitive or language problem. They also stated that Korean medicine has its advantage on strengthening the body to help grow and develop in CP children. However, the absence of guideline related to Korean medicine treatment in CP children as well as high cost are the problems. Finally, the issues regarding Korean medicine treatment in CP children, based on the in-depth interviews, emerged when western medicine is used simultaneously, when having seizure during treatment. Further research is needed for better understanding. Conclusions This study provided current status of the evidence-based Korean medicine treatment in CP children. However, further studies about the addressed issues are needed.