• Progress in Medical Physics
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• v.13 no.4
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• pp.181-186
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• 2002

The IMRT planning depends on the algorithm of each planning system and MLC performance of each Linac system. Yonsei Cancer Center introduced an IMRT System at the beginning of February, 2002. The system consists of CORVUS (Nomos, U.S.A.) treatment planning system, LANTIS, PRIMEVIEW and PRIMART (Siemens, U.S.A) linac system. The optimization of CORVUS planning system with PRIMART is an important task to make a desirable quality treatment plan. Our Step ＆ Shoot IMRT system uses Finite Size Pencil Beams (FSPB) dose model, simulated annealing optimization algorithm and IMFAST segmentation algorithm. We constructed treatment plans for four different patient cases with two basic beamlet sizes, 1.0$\times$1.0 $\textrm{cm}^2$ and 0.5$\times$1.0 $\textrm{cm}^2$, and four intensity steps, 5%, 10%, 20%, 33%. Each case's plan was evaluated with the dose volume histograms of target volumes and delivery efficiencies. The patient case of small target volume is sensitive at the change of intensity map's segmentation and it highlighted an effective treatment plan at marrow intensity step and small basic projection beamlet.

• Journal of the korean Society of Automotive Engineers
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• v.15 no.1
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• pp.81-88
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• 1993

A direct treatment of the min-max type objective function of the dynamic response optimization problem is proposed. Previously, the min-max type objective function was transformed to an artificial design variable and an additional point-wise state variable constraint function was imposed, which increased the complexity of the optimization problem. Especially, the design sensitivity analysis for the augmented Lagrangian functional with the suggested treatment is established by using the adjoint variable method and a computer program to implement the proposed algorithm is developed. The optimization result of the proposed treatment are obtained for three typical problems and compared with those of the previous treatment. It is concluded that the suggested treatment in much more efficient in the computational effort than the previous treatment with giving the similar optimal solutions.

• Progress in Medical Physics
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• v.23 no.2
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• pp.106-113
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• 2012

The purpose of this study is to evaluate the variation of radiation dose distribution for liver tumor located in liver dome and for the interest organs(normal liver, kidney, stomach) with the pencil beam convolution (PBC) algorithm versus anisotropic Analyticalal algorithm (AAA) of the Varian Eclipse treatment planning system, The target volumes from 20 liver cancer patients were used to create treatment plans. Treatment plans for 10 patients were performed in Stereotactic Body Radiation Therapy (SBRT) plan and others were performed in 3 Dimensional Conformal Radiation Therapy (3DCRT) plan. dose calculation was recalculated by AAA algorithm after dose calculation was performed by PBC algorithm for 20 patients. Plans were optimized to 100% of the PTV by the Prescription Isodose in Dose Calculation with the PBC algorithm. Plans were recalculated with the AAA, retaining identical beam arrangements, monitor units, field weighting and collimator condition. In this study, Total PTV was to be statistically significant (SRS: p=0.018, 3DCRT: p=0.006) between PBC and AAA algorithm. and in the case of PTV, ITV in liver dome, plans for 3DCRT were to be statistically significant respectively (p=0.013, p=0.024). normal liver and kidney were to be statistically significant (p=0.009, p=0.037). For the predictive index of dose variation, CVF ratio was to be statistically significant for PTV in the liver dome versus PTV (SRS r=0.684, 3DCRT r=0.732, p<0.01) and CVF ratio for Tumor size was to be statistically significant (SRS r=-0.193, p=0.017, 3DCRT r=0.237, p=0.023).

• Transactions of the Korean Society of Mechanical Engineers A
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• v.21 no.10
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• pp.1561-1570
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• 1997

This study explores the treatment of the max-value cost function over a parameter interval in parametric optimization. To avoid the computational burden of the transformation treatment using an artificial variable, a direct treatment of the original max-value cost function is proposed. It is theoretically shown that the transformation treatment results in demanding an additional equality constraint of dual variables as a part of the Kuhn-Tucker necessary conditions. Also, it is demonstrated that the usability and feasibility conditions on the search direction of the transformation treatment retard convergence rate. To investigate numerical performances of both treatments, typical optimization algorithms in ADS are employed to solve a min-max steady-state response optimization. All the algorithm tested reveal that the suggested direct treatment is more efficient and stable than the transformation treatment. Also, the better performing of the direct treatment over the transformation treatment is clearly shown by constrasting the convergence paths in the design space of the sample problem. Six min-max transient response optimization problems are also solved by using both treatments, and the comparisons of the results confirm that the performances of the direct treatment is better than those of the tranformation treatment.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.22 no.1
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• pp.25-37
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• 2011

Objectives：This study was conducted to develop a Korean algorithm of pharmacological and non-pharmacological treatment strategies in attention-deficit hyperactivity disorder (ADHD) and its specific comorbid disorders (e.g. tic disorder, depressive disorder, anxiety disorder, bipolar disorder, and oppositional defiant disorder/conduct disorder). Methods：Based on a literature review and expert consensus, both paper- and web-based survey tools were developed with respect to a comprehensive range of questions. Most options were scored using a 9-point scale for rating the appropriateness of medical decisions. For the other options, the surveyed experts were asked to provide answers (e.g., duration of treatment, aver-age dosage) or check boxes to indicate their preferred answers. The survey was performed on-line in a self-administered manner. Ultimately, 49 Korean child & adolescent psychiatrists, who had been considered experts in the treatment of ADHD, vol untarily completed the questionnaire. In analyzing the responses to items rated using the 9-point scale, consensus on each option was defined as a non-random distribution of scores as determined by a chi-square test. We assigned a categorical rank (first line/preferred choice, second line/alternate choice, third line/usually inappropriate) to each option based on the 95% confidence interval around the mean rating score. Results：Specific medication strategies for key clinical situations in ADHD and its comorbid disorders were indicated and described. We organized the suggested algorithms of ADHD treatment mainly on the basis of the opinions of the Korean experts. The suggested algorithm was constructed according to the templates of the Texas Child & Adolescent medication algorithm Project (CMAP). Conclusion：We have proposed a Korean treatment algorithm for ADHD, both with and without comorbid disorders through expert consensus and a broad literature review. As the tools available for ADHD treatment evolve, this algorithm could be reorganized and modified as required to suit updated scientific and clinical research findings.

• Journal of Electrochemical Science and Technology
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• v.14 no.2
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• pp.174-183
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• 2023

The dye wastewater discharge from the textile industries mainly affects the aquatic environment. Hence, the treatment of this wastewater is essential for a pollutant-free environment. The purpose of this research is to optimize the dye removal efficiency for process influencing independent variables such as pH, electrolysis time (ET), and current density (CD) by using Box-Behnken design (BBD) optimization and Genetic Algorithm (GA) modelling. The electrocoagulation treatment technique was used to treat the synthetically prepared Reactive Black dye solution under batch mode potentiometric operations. The percentage of error for the BBD optimization was significantly greater than for the GA modelling results. The optimum factors determined by GA modelling were CD-59.11 mA/cm², ET-24.17 minutes, and pH-8.4. At this moment, the experimental and predicted dye removal efficiencies were found to be 96.25% and 98.26%, respectively. The most and least predominant factors found by the beta coefficient were ET and pH respectively. The outcome of this research shows GA modeling is a better tool for predicting dye removal efficiencies as well as process influencing factors.

• Journal of Korean Academy of Nursing
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• v.41 no.6
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• pp.768-779
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• 2011

Purpose: This study was designed to adapt a surgical wound care algorithm that is used to provide evidence-based surgical wound care in a critical care unit. Methods: This study used, the 'ADAPTE process', an international clinical practice guideline development method. The -'Bonnie Sue wound care algorithm' - was used as a draft for the new algorithm. A content validity index (CVI) targeting 135 critical care nurses was conducted. A 5-point Likert scale was applied to the CVI test using a statistical criterion of .75. Results: A surgical wound care algorithm comprised 9 components: wound assessment, infection control, necrotic tissue management, wound classification by exudates and depths, dressing selection, consideration of systemic factors, wound expected outcome, reevaluate non-healing wounds, and special treatment for non-healing wounds. All of the CVI tests were ${\leq}$.75. Compared to existing wound care guidelines, the new wound care algorithm provides precise wound assessment, reliabilities of wound care, expands applicability of wound care to critically ill patients, and provides evidence and strength of recommendations. Conclusion: The new surgical wound care algorithm will contribute to the advancement of evidence-based nursing care, and its use is expected as a nursing intervention in critical care.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2006.08a
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• pp.99-99
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• 2006

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1995.10b
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• pp.153-158
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• 1995

In this paper, A new design method of fuzzy modeling is presented for the model identification of nonlinear complex systems. The proposed fuzzy GMDH modeling implements system structure and parameter identification using GMDH(Group Method of Data Handling) algorithm and linguistic fuzzy implication rules from input and output data of processes. In order to identify premise structure and parameter of fuzzy implication rules, GMDH algorithm and fuzzy reasoning method are used and the least square method is utilized for the identification of optimum consequence parameters. Time series data for gas furnaceare those for sewage treatment process are used for the purpose of evaluating the performance of the proposed fuzzy GMDH modeling. The results show that the proposed method can produce the fuzzy model with higher accuracy than other works achieved previously.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2019.05a
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• pp.367-371
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• 2019

'Scientificization' of oriental medicine is a task to be preceded for K-MEDI in the world. Also, We are trying to secure efficacy and safety through scientifically proving the efficacy of Oriental medicine. This paper. We propose a biomarker extraction algorithm for genetic lesion reading of Oriental medicine. Also, A variety of applications in terms of Oriental medicine. Oriental medicine was suggested as a basis for the diagnosis and treatment of the treatment.