• 제목/요약/키워드: Treatment Adherence

검색결과 178건 처리시간 0.025초

Protective Effect of Rutin on Splanchnic Injury Following Ischemia and Reperfusion in Rats

  • Lee, Hyang-Mi;Jang, Yoon-Young;Song, Jin-Ho;Kim, Kwang-Joon;Lim, In-Ja;Shin, Yong-Kyoo
    • The Korean Journal of Physiology and Pharmacology
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    • 제5권4호
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    • pp.323-331
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    • 2001
  • A splanchic artery occlusion for 90 min followed by reperfusion of the mesenteric circulation resulted in a severe form of circulatory shock characterized by endothelial dysfunction, severe hypotension, marked intestinal tissue injury, and a high mortality rate. The effect of rutin, a flavonoid having antiprostanoid, anti-inflammatory, antithrombotic, antioxidant effect, were investigated in a model of splanchnic artery occlusion (SAO) shock in urethane anesthetized rats. Occlusion of the superior mesenteric artery for 90 min produced a severe shock state resulted in a fatal outcome within 120 min of reperfusion in many rats. Rutin was given as a bolus (1.28 mg/kg) 10 min prior to reperfusion. Administration of rutin significantly improved mean arterial blood pressure in comparison to vehicle treated rats (p<0.05). Rutin treatment also resulted in a significant attenuation in the increase in plasma amino nitrogen concentration, intestinal myeloperoxidase activity, intestinal lipid peroxidation, infiltration of neutrophils in intestine and thrombin induced adherence of neutrophils to superior mesentric artery segments. These results suggest that rutin provides beneficial effects in part by preserving endothelial function and attenuating neutrophil accumulation in the ischemic reperfused splanchnic circulation.

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장기 투약대상자의 약물순응도를 높이기 위한 스마트 약상자의 구현 (Developing a Smart Pillbox to Improve the Medication Adherence of the Patients Requiring a Long-term administration)

  • 김범준
    • 한국전자통신학회논문지
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    • 제8권4호
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    • pp.611-617
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    • 2013
  • 결핵은 꾸준한 복약만 이루어진다면 완치될 수 있는 병임에도 불구하고 우리나라의 결핵 환자 발생률과 사망률은 매우 높은 수준이다. 이러한 상황을 극복하기 위하여 본 논문에서는 결핵과 같은 장기 투약대상자들이 정기적이고 꾸준하게 약을 복용할 수 있도록 하기 위한 스마트 약상자를 개발한다. 개발된 스마트 약상자에는 무게 측정을 통하여 약의 배출 여부를 판단할 수 있도록 0.1g 단위의 정밀한 무게 측정이 가능한 로드셀이 장착되었다. 그리고 무게 측정 결과 근거로 환자가 약을 복용했는지를 판단하기 위한 다양한 시나리오별 알고리듬을 개발하여 소프트웨어로 구현하였다.

PU매체에 부착한 유류분해 bacteria를 이용한 오염토양 처리 (Remediation of PAH-Polluted Soil by Pseudomonas sp. Adhered on PU Foam)

  • 조대철;허남수;권성현
    • 한국산학기술학회논문지
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    • 제7권3호
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    • pp.458-464
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    • 2006
  • 토양의 생물학적 복원은 산업화로 무차별하게 오염되어 있는 국내 산업단지 주변과 지하수 환경보전을 위한 경제적 도구로 인식되어왔다. 본 연구는 친환경적 생물복원을 위한 기초자료를 얻기 위하여 유류로 오염된 양토에서 Pseudomonas sp. (KCCM 40055)를 접종한 polyurethane 매체환경을 적용, 유류의 성분중 PAH 분해도를 조사하였다. 다공성 매체로서 재현성이 뛰어나며 미생물 부착에 활용되어 온 polyurethane foam을 사용하여 미생물 부착성을 아울러 조사하였다. 사용된 PU중 최저공극 foam인 SR9-35C/G 의 경우 부착률과 PAH분해율이 가장 높았으며 토양함수율 증가에 따라 그 효율이 증가하였다.

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아크이온플레이팅에 의한 질화 티탄-크롬의 박막특성 평가 (Evaluation for Thin Films Characteristics of Nitride Titanium-Chromium using Arc Ion Plating)

  • 후지타 카즈히사;양영준
    • 한국기계가공학회지
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    • 제10권4호
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    • pp.96-101
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    • 2011
  • The thin films of TiN have been used extensively as wear-resistant materials, for instance, such as tools of high-speed cutting, metal mold forming etc. In these days, because the thin films capable of being used more severe conditions are needed, the technologies of arc ion plating are tried to improve its characteristics. The purpose of this study is to investigate the characteristics of thin films of (Ti,Cr)N compared with those of TiN. The method of arc ion plating, which is known as showing good tight-adherence and productivity, was used. After manufacturing thin films of ($Ti_{1-x}Cr_{x}$)N (x=0~1) with change of Cr in (Ti,Cr) target, atomic concentration, structure, size of crystallite, residual stress and surface roughness of thin films on substrate were investigated. As the results, it was confirmed that Cr atomic concentrations of thin films were proportionally changed with Cr atomic concentrations of target, and thin films of ($Ti_{1-x}Cr_{x}$)N (x=0~1) showed NaCl type and CrN existed as solid solution to TiN.

A study of palm oil mill processing and environmental assessment of palm oil mill effluent treatment

  • Akhbari, Azam;Kutty, Prashad Kumaran;Chuen, Onn Chiu;Ibrahim, Shaliza
    • Environmental Engineering Research
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    • 제25권2호
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    • pp.212-221
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    • 2020
  • This work discusses the palm oil mill processing carried out at Jugra Palm Oil Mill Sdn Bhd, situated at Selangor, Malaysia with the capacity of 45-t fresh fruit bunch (FFB)/h. Typically, oil palm residues and palm oil mill effluent (POME) from FFB are generated while processing. Prior to discharge, POME should be treated to remove pollutants in the effluent. As such, the performances of anaerobic and aerobic ponds were assessed in this study to determine temperature, pH, biological oxygen demand (BOD), sludge volume index (SVI), and dissolved oxygen (DO). From the experiments, mesophilic temperature due to better process stability was applied in anaerobic ponds. The pH results displayed a fluctuating trend between lower control limit and upper control limit, and, the pH value increased from one pond to another. The final discharge BOD and SVI appeared to be lower than 100 mg/L and 10 mL/L indicating low degree of pollution and good settling ability for biomass/solid. DO was close to normal, mostly below 2 mg/L. The experimental outcomes revealed the effective treatability of POME in adherence to the standard regulation, which is the priority for environmental sustainability within this industry domain.

CARE 지침에 따른 대한한의학회지의 증례보고에 대한 질 평가 (Evaluation of the Quality of Case Reports from the Journal of Korean Medicine Based on the CARE Guidelines)

  • 최성열
    • 대한한의학회지
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    • 제41권2호
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    • pp.122-136
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    • 2020
  • Objectives: A case report is a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient. The purpose of this study is to evaluate the quality of case reports from the Journal of Korean Medicine by the CARE (CAse REport) Guideline. Methods: Case reports published in the Journal of Korean Medicine from January 2016 to March 2020 were searched from Oriental Medicine Advanced Searching Integrated System (OASIS). We assessed the quality of reporting based on CARE (CAse REport) guideline as 'Sufficient', 'Not-Sufficient' and 'Not-Report'. Results: A total of 22 case reports were finally included for the assessment. The reporting items were reported as of reporting quality. After checking the result, there was a deviation in the sub-item reporting rate by a maximum 89.29%, a minimum 66.67% and a median 82.14% in case reports. Also after checking the quality in case reports by 28 detailed items in CARE guidelines, there were not reported 77% or more in the 5 sub-items 'Intervention adherence and tolerability', 'Informed consent', 'Adverse and unanticipated events', 'Diagnostic challenges', 'Patient perspective'. Conclusion: There is a need to improve the quality of case reports in the journal of Korean Medicine based on various studies using CARE guideline.

임플란트 나사의 안정성 (Stability of implant screw joint)

  • 정재헌;곽종하;장두익
    • 구강회복응용과학지
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    • 제19권2호
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    • pp.125-137
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    • 2003
  • The use of screw-retaind prosthesis on an osseointegrated implant is a popular treatment modality offering relative ease in the removal of the restoration. One of the complications associated with this modality is the loosening of the abutment and coping screws. Loosening of the screws results in patient dissatisfaction, frustration to the dentist and, if left untreated, component fracture. There are several factors which contribute to the loosening of implant components which can be controlled by the restorative dentist and lab technician. This article offers pratical solutions to minimize this clinical problem and describes the factors involved in maintaining a stable screw joint assembly. To avoid joint failure, adherence to specific clinical, as well as mechanical, parameters is critical. With respect to hardware, optimal tolerance and fit, minimal rotational play, best physical properties, a predictable interface, and optimal torque application are mandatory. In the clinical arena, optimal implant distribution; load in line with implant axis; optimal number, diameter, and length of implants; elimination of cantilevers; optimal prosthesis fit; and occlusal load control are equally important.

산화피막의 파괴거동 및 산화피막이 소지금속의 기계적 강도에 미치는 영향 (Fracture Behavior of Oxide Scales and Influence of Oxide Scales on the Strength of Materials)

  • 손일령;최진원
    • 소성∙가공
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    • 제13권1호
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    • pp.72-77
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    • 2004
  • An Fe-25Cr steel was oxidized in Ar atmosphere at 973K with and without applying external stress of 30∼35 MPa. A 0.1$\mu\textrm{m}$ thick $Cr_2O_3$ scales formed during pre-treatment in Ar atmosphere. Initiation of cracking on the oxide scales took place at grain boundaries during the end of second creep stage, in which cracks were found nearly perpendicular to the tensile directions. On the contrary, a scale developed in $N_2$-0.1%$SO_2$ displaced a poor adherence on the metal substrate. In this sample, a fast grown of scales was observed during creep deformation, and the strength of materials was much lower than in Ar. The creep strain rate of $1.5{\times}10^{-7}/s$ and $5.8{\times}10^{-7}/s$ was determined in Ar and in $N_2$-0.1%$SO_2$ under 30MPa, respectively.

Medicinal plants used in the management of diabetes by traditional healers of Narok County, Kenya

  • Kamau, Loice Njeri;Mbaabu, Peter Mathiu;Karuri, Peter Gathumbi;Mbaria, James Mucunu;Kiama, Stephen Gitahi
    • 셀메드
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    • 제7권2호
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    • pp.10.1-10.10
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    • 2017
  • The Maasai community from Kenya is highly esteemed for their strong adherence to traditional cultures and ethno medicine. This is attributed to their age-old traditional mechanisms of passing down knowledge to the younger generation. Adoption to new socio-economic lifestyle and urbanization has been associated with development of diabetes, which has been reported among some indigenous pastoral communities in Kenya. Documentation of traditional methods of treatment and management of diabetes by the Maasai has not yet been reported, yet it is noteworthy. Thirty traditional healers from Narok County were purposively selected and interviewed about traditional knowledge of antidiabetic medicinal plants, parts used, preparation dosage and administration. A total of 14 antidiabetic plant species distributed within 13 genera and 12 families were identified and documented as herbal medicine used in the management of diabetes. The most highly cited plant species was Dovyalis abyssinica (20%), the plant family Flacourtiaceae and Rhamnaceae (2 plant species each) recorded the highest number of plant species while the most frequently used plant part was the roots (46%). Literature review revealed that some of the cited plants have known phytochemicals with antidiabetic activity; the study recommends further scientific investigation to validate their efficacy and safety.

항투명대 항체의 특성에 관한 연구 II. 항투명대 항체가 돼지난자와 생쥐난자의 체외수정에 미치는 영향 (Studies on the Characteristics of Anti-Zona Antibody II. Effect of Anti-Zona Antibody on Fertilization of Porcine and Mouse Eggs In Vitro)

  • 김은영;박세필;정형민;정길생;김종배
    • 한국가축번식학회지
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    • 제14권2호
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    • pp.115-124
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    • 1990
  • These experiments were undertaken as a basic study to develop immunocontraceptive vaccine and to understand the role of zona pellucidae in early fertilization process by investigating the effect of monoclonal and polyclonal antibody to porcine zona pellucidae and polyclonal antibody to mouse zona pellucidae on the fertilization of porcine and mouse eggs in vitro. The results obtained in these experiments were summarized as follows : 1. Treatment of porcine and mouse eggs with undiluted anti-zona serum produced intense precipitation layer on the poricne and mouse zonae, respectively, thus resulting in the total inhibition of sperm adherence on surface of zona. 2. In vitro fertilization of eggs pre-treated with 0.3∼10% of various antibodies was examined, and resulting in that 5 and 10% of rabbit polyclonal antibodies to porcine zona inhibited completely both in vitro fertilization and polyspermy of porcine eggs while monoclonal to porcine zona and rabbit polyclonal antibody to mouse zona did not inhibit in vitro fertilization but monoclonal antibody reduced the rate of polyspermy compared to that of control group. Almost the same results were obtained in the study on the effect of anti-zona serum on in vitro fertilization of mouse eggs.

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