• Journal of Integrative Natural Science
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• v.11 no.2
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• pp.101-106
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• 2018

Corticotropin - releasing hormone receptor 1 (CRHR1) forms an integral part of the pathophysiology of disorders like post-traumatic stress disorder, stress, anxiety, addiction, and depression. Hence it is essential to look for new, potent and structure-specific inhibitors of CRHR1. We have analysed the protein-protein interaction complexes of the CRHR1 receptor with its native ligand CRF and full agonist Sauvagine. The structure of Sauvagine was predicted using homology modelling. We have identified that the residues TYR253, ASP254, GLU256, GLY265, ARG1014 and LY1060 are important in the formation of protein-protein complex formation. Future studies on these residues could throw light on the crucial structural features required for the formation of CRHR1-inhibitor complex and in studies that try to solve the structural complexities of CRHR1.

• Journal of Integrative Natural Science
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• v.11 no.1
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• pp.19-24
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• 2018

CRFR is involved in the pathophysiology of various disorders including depression, stress, anxiety, post-traumatic stress disorder, and addiction. The discovery of novel and structurally diverse CRF1 receptor inhibitors becomes essential. In this study, we have performed molecular docking of CRF1R with the derivatives of 8-substituted-2-aryl-5-alkylaminoquinolines as CRF1R inhibitors. The antagonist molecules were optimized and docked into the binding site of the receptor. On analysing the docked complexes we have identified that the residues HIS214, THR215, ARG227, ARG1008, LYS1060 and ASP1061 are important in forming hydrogen bond with the inhibitors. Further studies on these residues could reveal important structural features required for the formation of CRF1R-inhibitor complex and thus in the discovery of novel and potent inhibitors.

• Anxiety and mood
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• v.15 no.1
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• pp.35-44
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• 2019

Objective : The aim of this study was to investigate the individual and job related factors as risk factors for mental health of firefighters. Methods : The data of 202 fire-fighters was analyzed by using a multinomial logistic regression analysis. All participants completed self-reported questionnaires including demographics (sex, age, work duration), the Childhood Trauma Questionnaire, the Ways of Coping Checklist, the Colleague related traumatic events, the Korean occupational stress scale, the Korean Perceived Stress Scale-10, and the Beck Depression Inventory. Participants were divided into three groups according to the level of stress and depressive symptom scores: Low Stress-Low Depression (LS-LD), High Stress-Low Depression (HS-LD), and High Stress-High Depression (HS-HD). Results : A job related factor-organizational injustice-was a significant factor related to HS-LD, while individual factors such as active coping level and childhood trauma experience and a job related factor-difficult physical environment-were significantly associated with HS-HD. Conclusion : These results imply the need to take both individual and environmental approaches into account when managing the stress and depression of firefighters. More specifically, psycho-education to facilitate active coping strategy and adaptive emotional regulation at the individual level and the improvement of physical work environment of firefighters should be supported.

• Korean Journal of Psychosomatic Medicine
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• v.28 no.1
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• pp.42-52
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• 2020

Objectives : Firefighters are always under stress due to their job environment, and they are likely to become psychologically vulnerable due to continuous exposure to traumatic events, which is a stressful situation that requires emergency standby at all times. The aims of this study were to examine mental health factors for each division of firefighters and to see the relationship between sleep and somatization symptoms among them. Methods : General characteristics and related inspections were conducted through self-reporting questionnaires for 1,264 firefighters working at Chungbuk fire stations. Several mental health factors were investigated by the Insomnia Severity Index, Severity of somatic symptoms, Impact of Event Scale, Perceived Stress Scale, Resilience Scale, Alcohol Dependent Screening Scale, and the Center for Epidemiologic Studies Depression Scale Depression Scale and Mini-International Neuropsychiatric Interview. Results : Among the mental health variables, the relationship between insomnia and somatization varies significantly depending on types of work. It was reported that the first aid team was significantly higher than the fire suppression and rescue team. Post-traumatic stress, depression and drinking also differ significantly depending on types of work. The first aid team reported more posttraumatic stress than the fire suppression team and more depressed mood than the rescue team. The administration part had more alcohol consumption than the fire suppression or first aid team. Resilience was significantly higher in the rescue team than the first aid team. No significant differences between the types of work about stress and suicide risks. Insomnia, stress, and post-traumatic stress were significant predictors of somatization among firefighters. Above all, insomnia was significant mental health variable affecting somatization. Conclusions : Various mental health factors were different according to the types of work in firefighters. The First aid team was more vulnerable to mental health variables such as insomnia and somatization than other divisions. Insomnia is the most important cause of somatization in firefighters, so it is recommended that they be treated for insomnia and to prepare institutional policies.

• Journal of the Korean Society of Child Welfare
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• no.36
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• pp.289-322
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• 2011

The purpose of this study is to examine the relationship between job characteristics such as role conflict, workload, and self-efficacy, secondary traumatic stress(STS), and burnout of social-workers who are working with survivors of child abuse, spouse abuse and sexual assault. While burnout has been studied over two decades all over the world, secondary traumatic stress(STS) is a less familiar term in the field of social work. Studies explaining the relationship between job-demands, STS, and burnout for social workers working with violence victims lack integrative insights across agencies serving children and adults. Thus, we examine whether the relationships between change based on wheter the survivor is a child or an adult. Two hundred thirty three social workers in Korea who work with violence victims participated in the survey. The data were analyzed with Amos 7.0. Results indicate that STS plays a key role in explaining social worker burnout across the agencies, and Child Protective Service workers were found to have the highest STS symptoms. The pathways to social worker burnout proved to be different based on who you served. Theoretical and practical implications of these findings were discussed.

• Journal of Navigation and Port Research
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• v.38 no.6
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• pp.615-621
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• 2014

VTS operators may suffer from acute, chronic, or traumatic stress caused by their workload and working environments associated with task or combination of task. This study intended to measure the level of VTS operator' stress and find out factors influencing it by understanding their characteristics during carrying out their task. For this purpose, analyzed the data collected through conducting survey on VTS operators as the Korea Occupational Stress(KOSS) and Psychological Well-being Index(PWI). As a result, VTS operators are experiencing higher level of psychological stress than the national average. And the factors to cause VTS operators' occupational stress can be summarized as follows; working environment factors, shift work especially night duty, workload, etc. This study provides the fundamental information for understanding human factors of VTS operator' occupational stress.

• Journal of Preventive Medicine and Public Health
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• v.43 no.3
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• pp.265-273
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• 2010

Objectives: Due to the economic crisis and globalization, many workers have been suffering from severe occupational stress due to job insecurity and struggles related to downsizing and restructuring. This study aims to assess the stress levels among workers involved in fierce labor disputes and massive layoffs and to evaluate their specific needs and satisfaction with counseling services set up to help workers cope with severely stressful situations? Methods: The authors provided crisis intervention to workers in traumatic situations to compare the differential level of stress responses and needs among the workers remaining employed in a large auto factory, those laid off by it, and those laid off by other companies in the same region (Pyeongtaek, Gyeonggi Province). We measured stress levels using the worker's stress response inventory (WSRI) and heart rate variability (HRV), and assessed workers' satisfaction with the counseling services. Results: 502 workers participated in the program. Fifty-seven percent of them consulted with occupational problems. The mean WSRI score of the workers remaining employed in the automobile factory was higher than that of the unemployed (employed: $39.8{\pm}19.9$ unemployed: $29.3{\pm}18.8$). Ninety-five percent of workers responded that they were satisfied or very satisfied with the counseling services. Conclusions: This study suggests the urgent need for the establishment of a national crisis intervention program dedicated to supporting workers in severely stressful situations.

• Journal of the Society of Disaster Information
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• v.14 no.1
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• pp.17-27
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• 2018

The purpose of this study was to investigate the individual change, disaster awareness, and psychological stress of rural residents who experienced natural disasters, and to find measures to cope with the disaster of rural residents. The subjects of this study were rural residents living in Cheongju city, Chungcheongnamdo province, which suffered direct or indirect damage due to heavy rain in July, 2017. Survey and interview methods were used. There were significant differences in perception of disaster according to gender, and many residents were suffering from post traumatic stress. Finally, the present study suggests directions for growth after the disaster of rural people.

• Journal of People, Plants, and Environment
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• v.24 no.6
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• pp.693-705
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• 2021

Background and objective: This study was conducted to investigate the effects of forest therapy programs on reducing post-traumatic stress disorder (PTSD), depression and improving mood states in fire officers. Methods: To determine PTSD, depression, and mood states before and after the forest therapy program, the survey results of 185 fire officers were analyzed. Frequency analysis was conducted to identify the demographic characteristics of the participants, and Wilcoxon signed-rank test to analyze the differences among group. Results: As a result of a comparative analysis of PTSD before and after the program, there was a significant decrease in PTSD from 10.65 ± 12.00 to 5.64 ± 8.29 after the program. Depression also showed a statistically significant difference from 3.21 ± 4.00 to 2.21 ± 3.47 after the program. As a result of comparatively analyzing mood states before and after the program, there was an increase in positive factors and a decrease in negative factors. Total mood disturbance (TMD) also showed a statistically significant decrease from 5.78 ± 17.37 to -7.38 ± 10.35 after the program. Conclusion: This study has significance in verifying that forest therapy programs can bring psychological changes to fire officers, and these results can be used as a basis for stress management and relief of fire officers.

• Journal of Acupuncture Research
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• v.26 no.6
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• pp.161-169
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• 2009

Objectives : This study was to investigate the correlation of subjective stress caused by traffic accident with patient's prognosis. Methods : We investigated 53 cases of in-patient with traffic accident. The patients answered that questionnaire about subjective pain and stress on hospitalization day and leaving hospital day. And we calculated statistically signification with this data. Results 1. IES-R-K score of female group was significantly higher than male group's. 2. There was statistically significant correlation between IES-R-K score and admission duration. 3. After hospitalization treatment, there was statistically significant reduction of VAS and IES-R-K score. Conclusions : There was significant correlation between subjective stress and prognosis.