• 대한지리학회지
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• 제38권1호
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• pp.48-69
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• 2003

식민화는 정치경제적인 현상일 뿐만 아니라 사람, 작물, 잡초 가축. 병원균의 이식을 수반하는 생태적 제국주의의 또 다른 표현이다. 일제시대 한반도는 일본에서 개발한 신품종 벼가 도입. 개발, 보급되는 생물학적 식민주의의 실험장이었다. 신품종은 빠르게 퍼져나가 강점기 후반이 되면 수도 재배면적의 90%이상을 점거할 정도로 성장하였다. 신품종의 전파에는 일차적으로 농업이민, 농장. 권농기관. 농업연구기관이 관여하였다. 제도와 정책적인 측면의 지원도 활발했는데. 장려품종 지정. 품평회 개최. 곡물검사소 설치. 중견인물양성소 설립, 농회보를 통한 소개의 형식으로 이루어졌다. 화학비료의 투입을 전제로 하는 신품종 벼는 먼저 자본이 부족한 소농의 입지를 축소시켰다. 생산된 미곡은 대부분 반출되어 국내의 식량문제를 초래하였고, 농민으로서는 일본 소비시장의 기호변화에 맞추어 영농을 하지 않을 수 없는 등 왜래 품종의 이식으로 한반도의 종속적인 상황은 더욱 강화되었다. 일선 농촌에서는 새로운 농법과 영농설비의 도입으로 우리 고유의 문화경관이 크게 변질되었다.

• Journal of Chest Surgery
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• 제34권12호
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• pp.956-959
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• 2001

이식 후 발생하는 임파구 증식성 질환은 장기 이식의 예가 늘어나면서 증가하는 추세이며 폐 ,심장 이식과 같이 면역 억제 요법의 강도가 심할수록 그 발생률이 높아진다. 특히 임파구 증식성 질환 중 악성 임파종은 치료가 어렵고 예후가 좋지 않아 신속한 진단 및 치료가 필요하다. 본원에서는 1999년 11월 말기 폐기종으로 호흡 곤란이 심해져 가는 37세 A형 여자 환자에 0형 남자 환자의 좌측 폐를 이식하였다. 폐 이식 수술 후 면역 억제를 위해 3제 치료(싸이클로스포린, 아자씨오프런, 프레드니졸론)를 시행하였고, 환자는 이식 후 특별한 문제없이 외래 추적 관찰 중 정기적으로 시행한 가슴 컴퓨터 단층 촬영 상 이식 폐에 비정상적 종괴가 보여 2001년 2월 gun biopsy 시행 후 악성 임파종으로 진단을 받았으며 면역 억제제 감량 후 항암 화학요법 2회 시행하고 경과 관찰 중 갑자기 발생한 이식 폐부종으로 사망하였다.

• 동의생리병리학회지
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• 제19권2호
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• pp.389-397
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• 2005

This experimental Study was designed to investigate the effects of Acanthopanacis Cortex Extract(ACE) on the immunity, anti-cancer and obesity in mice. The results were as follows; ACE was significantly increased in the proliferation of thymocytes and splenocytes, and NO production from peritoneal macrophages in normal mice. ACE was significantly increased in the proliferation of thymocytes and splenocytes, and NO production from peritoneal macrophages in L1210 cells transplanted mice. ACE was significantly decreased in the proliferation of L1210 cells in L1210 cells transplanted mice. ACE was significantly inhibited body weight and tumor weight in S-180 cells transplanted mice. ACE was significantly increased in the mean survival days in S-180 cells transplanted mice. ACE was significantly decreased in the body weight in rats fed high fat diet. ACE was significantly decreased in the serum total cholesterol level, free fatty acid level, total lipid level, phospholipid level in rats fed high fat diet. According to above results, the authors suggest that ACE is able to be used for the herb of physiological-action.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2022년도 추계학술대회
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• pp.167-167
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• 2022

Seed production of italian ryegrass has a problem of lodging during ripening and a decrease in quality due to difficulty in drying seeds during harvest. Therefore, in order to produce high-quality Italian ryegrass in paddy fields, it was carried out to reduce the density and solve the lodging problem through transplanting. In this experiment, Lolium multiflorum cv. Kowinearly was transplanted in autumn from a paddy field in Sindong-ri, Gwansan-eup, Jangheung-gun, Jeollanam-do. var. Kowinearly was made into a bed at 90 g/box and stacked in boxes. It was transplanted on October 27th after 2 days of germination at 30℃ and 15 days of seedling and greening. When transplanting, they were transplanted at intervals of 30×14cm. The existing cultivation method, drill seedling, was sowed at a level of 50 kg/ha, and both transplanting and drilling were carried out at a nitrogen fertilization rate of 45 kg/ha. The number of ears during transplant cultivation was 1,016/m² and the drilling tended to be higher at 2,278/m², but this was probably due to the difference in seeding amount. The seed number of an ear tended to be 56% higher in transplantation, which had a significant impact on yield. The seed yield was 2,096 ka/ha in transplantation, which was 21% higher than that of drilling. When looking at the relationship with weed occurrence, there were areas where all the weeds, such as amul foxtail, occurred due to the low density. Even in the same transplanting area, the seed yield was about 1,000kg/ha less in the area where the weeds were abundant. It seems that weed management is important in paddy cultivation. Therefore, it seems necessary to develop an exclusive herbicide for Italian ryegrass cultivation.

• International Journal of Stem Cells
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• 제16권4호
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• pp.415-424
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• 2023

Therapeutic efficacy of mesenchymal stem cells (MSCs) is determined by biodistribution and engraftment in vivo. Compared to intravenous infusion, biodistribution of locally transplanted MSCs are partially understood. Here, we performed a pharmacokinetics (PK) study of MSCs after local transplantation. We grafted human MSCs into the brains of immune-compromised nude mice. Then we extracted genomic DNA from brains, lungs, and livers after transplantation over a month. Using quantitative polymerase chain reaction with human Alu-specific primers, we analyzed biodistribution of the transplanted cells. To evaluate the role of residual immune response in the brain, MSCs expressing a cytosine deaminase (MSCs/CD) were used to ablate resident immune cells at the injection site. The majority of the Alu signals mostly remained at the injection site and decreased over a week, finally becoming undetectable after one month. Negligible signals were transiently detected in the lung and liver during the first week. Suppression of Iba1-positive microglia in the vicinity of the injection site using MSCs/CD prolonged the presence of the Alu signals. After local transplantation in xenograft animal models, human MSCs remain predominantly near the injection site for limited time without disseminating to other organs. Transplantation of human MSCs can locally elicit an immune response in immune compromised animals, and suppressing resident immune cells can prolong the presence of transplanted cells. Our study provides valuable insights into the in vivo fate of locally transplanted stem cells and a local delivery is effective to achieve desired dosages for neurological diseases.

• 한국작물학회지
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• 제50권spc1호
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• pp.33-36
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• 2005

재배시기가 중산간지에서 생산된 쌀 품질에 미치는 영향을 구명하기 위하여, 중산간지에 추천된 품종(삼천벼, 상미벼, 화영벼, 주남벼)을 대상으로 5월 10일부터 6월 9일까지 10일 간격으로 4회에 걸쳐 이앙${\cdot}$재배한 3년간의 결과를 분석한 쌀품질 분석 결과를 요약하면 다음과 같다. 1. 식미치 분석결과 재배시기와 품종간의 상호작용 효과가 있어, 5월 10일 이앙재배에서는 상미벼, 화영벼, 주남벼가 삼천벼에 비해, 5월 20일 이앙재배에서는 상미벼와 주남벼가 삼천벼에 비해, 5월 30일 이앙재배에서는 상미벼와 화영벼가 삼천벼와 주남벼에 비해, 6월 9일 이앙재배에서는 상미벼와 삼천벼가 화영벼와 주남벼에 비해 식미치가 높았다. 따라서 상미벼가 4처리의 모든 이앙기에서 식미치가 높은 것으로 나타났다. 2. 아미로스 함량도 재배시기와 품종간에 상호작용 효과가 인정된바, 5월 10일과 5월 30일 이앙재배에서는 품종간의 아미로스함량에 유의차가 없었고, 5월 20일 이앙재배에서는 상미벼와 삼천벼가 주남벼보다, 6월 9일 이앙재배에서는 상미벼와 삼천벼가 화영벼와 주남벼 보다 아미로스 함량이 낮게 나타났다. 3. 단백질 함량은 이앙시기 중 6월 9일 이앙이, 품종 중에서는 주남벼가 가장 낮았다. 4. 완전미의 수량은 이앙시기 및 품종간의 유의차가 없었다. 5. 백미의 수량은 5월 20일 이앙이 5월 30일과 6월 9일 이앙재배보다 높았고, 품종간의 유의차는 없었다. 6. 본 실험 처리 중 중산간지 고품질 쌀 생산에 가장 유리한 이앙기는 5월 20일, 품종은 상미벼인 것으로 분석되었다.

• Animal cells and systems
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• 제6권3호
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• pp.215-219
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• 2002

In mid-April, 2000, hundreds of thousands of fish floated dead on the Chungnang River, one of the small branches of the Han River in Seoul. We examined the causes of the accident in detail, through analysis of monitorinq data from the Han River Monitoring Project, which employed the transplanted aquatic moss, Fontinalis antipyretica. This allowed investigation of another possible cause of the fish kill: release of trace metals into the river from industrial sources during the rainfall event. In addition, we aimed to verify the usefulness of aquatic mosses as bioindicators of the event. Water samples collected 48 h after the fish kill exhibited low pH and high Total-N and Total-p, indicating that acidic compounds rich in nitrogen and phosphorus might be a major contaminant. BOD and COD were also very high. On the whole, the conditions of the river water were degraded at that time. Distinct trends were not observed in the chlorophyll phaeophy-tinization quotient and photosynthesis rate of transplanted mosses. How-ever mosses sampled soon after the accident exhibited the lowest values for those variables (P < 0.01), suggesting that stress factors in the river were diluted out over time. Heavy metals with characteristics of industrial effluents (Cr, Pb, Zn, Fe, Cu, and Cd) increased (p ＜ 0.01), indicating that they were unlikely to be major causes of the accident.

• 대한간호학회지
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• 제33권3호
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• pp.365-375
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• 2003

Purpose: This study was aimed to investigate the health related quality of life and related factors of organ transplant recipients. Method: The participants were 188 people who had liver(86), kidney(81), or heart(24) transplanted. Data on the demographic characteristics, transplantation-related characteristics, symptom frequency or discomfort measured by Transplant Symptom Frequency and Symptom Distress Scale by Lough et al(l987), and health related quality of life measured by SF-36(version 2) were collected. Result: Overall health related quality of life score was 492.1 for 100scoring and, 344.9 for norm based. Physical functioning showed the highest quality of life score (77.5) and vitality showed the lowest(51.l). The kidney transplanted showed the highest quality of life (504.4) and the heart transplanted showed the lowest(426.7) Quality of life was related with occupation(p=.016) and symtom discomfort(p < .0001). Conclusion: The health related quality of life of transplated patients was lower than the norm of American. Further studies need to be done to identify the norm of Korean and to investigate the effect of releving symptom discomfort on the increasing the health related quality of life.

• 한방안이비인후피부과학회지
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• 제19권1호
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• pp.93-102
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• 2006

Objective : Gamisibgi-San was a drug that treated carbuncle and cellulitis. So, the purpose of this Study was to investigate effects of Gamisibgi-San on the anti-cancer and proliferation of immunocytes. Materials and Method : We used Gamisibgi-San extract(GMSGS) with freeze-dried, 8wks-old male mice and cancer cell lines(L1210, S-180) for this Study. The cytotoxicity and proliferation of cells wat tested using a colorimetric tetrazoliun assay(MIT assay). Results and Conclusion : The results of this Study were obtained as follow ; 1. GMSGS was significantly showed cytotoxicity on the L1210 cell lines and S-180 cell lines. 2. GMSGS was significantly increased in the proliferation of thymocytes and splenocytes in vitro. 3. GMSGS was significantly decreased in the proliferation of L1210 cells in L1210 cells transplanted mice. 4. GMSGS was significantly decreased in the Weight of Sarcoma in S-180 cells transplanted mice. 5. GMSGS was significantly increased in the Period of Survive in S-180 cells transplanted mice. The present author thought that GMSGS had action of anti-cancer by becoming immunocytes activity(proliferation of thymocytes and splenocytes).

• 한방안이비인후피부과학회지
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• 제19권1호
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• pp.31-42
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• 2006

Objective : This Study was to investigate effects of Takliikgi-tang on the anti-cancer and proliferation of immunocytes, nitric oxide (NO) production of peritoneal macrophages. Methods : We used Takliikgi-tang extract (TLT) with freeze-dried, 8weeks-old male mice and cancer cell lines (L1210, Sarcoma-180) for this Study. The cytotoxicity and proliferation of cells were tested using a colorimetric tetrazoliun assay (MTT assay). Results : 1. TLT was significantly showed cytotoxicity on the L1210, 5-180 cell lines. 2. TLT was significantly increased proliferation of thymocytes in vitro. 3. TLT was significantly increased proliferation of thymocytes and splenocytes in normal mice. 4. TLT was significantly increased NO production from peritoneal macrophages in normal mice. 5. TLT was significantly decreased proliferation of L1210 cells in L1210 cells transplanted mice. 6. TLT was significantly increased proliferation of thymocytes and splenocytes by all-dosage in L1210 cells transplanted mice. 7. TLT was significantly increased NO production from peritoneal macrophages in L1210 cells transplanted mice. Conclusions : The present author thought that TLT had action of anti-cancer by becoming immunocytes activity (NO production, proliferation of thymocytes).