Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Experimental Effects of Acanthopanacis Cortex Extract on the Immunity, Anti-Cancer and Obesity in Mice

오가피(五加皮) 추출액(抽出液)이 면역(免疫), 항암(抗癌) 및 비만(肥滿)에 미치는 실험적 효과

  • Rho, Young-Ho (Department of Pathology, College of Oriental Medicine, Dongshin University) ;
  • Lee, Geum-Su (Department of Pathology, College of Oriental Medicine, Dongshin University) ;
  • Kim, Cheon-Joong (Department of Pathology, College of Oriental Medicine, Dongshin University) ;
  • Jeon, Byung-Gwan (Department of Environmental Engineering, Dongshin University) ;
  • Jeong, Hyun-Woo (Department of Pathology, College of Oriental Medicine, Dongshin University)
  • 노영호 (동신대학교 한의과대학 병리학교실) ;
  • 이금수 (동신대학교 한의과대학 병리학교실) ;
  • 김천중 (동신대학교 한의과대학 병리학교실) ;
  • 전병관 (동신대학교 환경공학과) ;
  • 정현우 (동신대학교 한의과대학 병리학교실)
  • Published : 2005.04.25
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Abstract

This experimental Study was designed to investigate the effects of Acanthopanacis Cortex Extract(ACE) on the immunity, anti-cancer and obesity in mice. The results were as follows; ACE was significantly increased in the proliferation of thymocytes and splenocytes, and NO production from peritoneal macrophages in normal mice. ACE was significantly increased in the proliferation of thymocytes and splenocytes, and NO production from peritoneal macrophages in L1210 cells transplanted mice. ACE was significantly decreased in the proliferation of L1210 cells in L1210 cells transplanted mice. ACE was significantly inhibited body weight and tumor weight in S-180 cells transplanted mice. ACE was significantly increased in the mean survival days in S-180 cells transplanted mice. ACE was significantly decreased in the body weight in rats fed high fat diet. ACE was significantly decreased in the serum total cholesterol level, free fatty acid level, total lipid level, phospholipid level in rats fed high fat diet. According to above results, the authors suggest that ACE is able to be used for the herb of physiological-action.

Keywords

References

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