• Herbal Formula Science
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• v.21 no.2
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• pp.13-28
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• 2013

Objectives : Term standardization is the most important for knowledge information in every study. There are several tries to make terminology standards in Korean Traditional Medicine(KTM). We, authors took a review on romanized prescription nomenclature of main titles in Herbal Formula Science to criticize the ways of romanized prescription nomenclature. Methods : We extract romanized prescription name from Vol. 11, No. 1 to latest Issue Vol. 21, No. 1, Herbal Formula Science. Results : The Korean Academy of Oriental Medicine Prescription has guideline for romanized prescription nomenclature. However, only 6 out of 147 romanized prescription name are confirmed with guideline. In addition, 58 out of 142 names are italicized without guideline. Also there are several ways of marking for prescription names. Conclusions : For making knowledge information and easy searching for terms, we need normative regulations for romanized prescription nomenclature by the Society of Korean Medicine level.

• The Journal of Korean Medicine
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• v.44 no.3
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• pp.189-200
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• 2023

Objectives: The purpose of this study is to analyze the current state of quantitative literature evidence for the prescription of 56 herbal medicines covered by health insurance that have been studied in Korea for the past 30 years, to evaluate the reliability of the evidence, and to find out the research direction of herbal medicine prescription in the future. Methods: 56 kinds of herbal medicine prescriptions were searched in domestic literature search databases OASIS, DBpia, and overseas PubMed, classified into chemistry, toxicity, cells, animals, clinical cases, and clinical trial studies, and built into an EBM pyramid structure. Results: When classified according to research contents, there were 61 cases (7.5%) of physicochemical analysis to identify constituent substances, 80 cases (9.8%) of toxicity evaluation, and 672 cases (82.7%) of efficacy evaluation. The efficacy evidence was classified according to the evidence-based medical pyramid structure: 196 cell trials (29.1%), 372 animal trials (55.4%), 89 case and case reporting series (13.3%), 7 comparative case studies (1.1%), and 8 randomized control clinical trials (1.2%). In the pyramid composition, the basis for the validity of 56 kinds of herbal medicines prescribed was 568 cases (84.5%) in cell and animal units, which could not be said to be highly reliable. There was no relationship between the ranking of quantitative literature evidence for herbal medicine prescriptions and the ranking of salary administration. Conclusions: In an era that continues to require scientific evidence for herbal medicine, traditional herbal medicine should secure the basis for safety validity even for the 10th most frequent prescription among 56 herbal medicine prescriptions for consumers. In particular, traditional herbal medicine should increase the quantitative and qualitative level of case reports on related herbal medicine prescriptions, focusing on each clinical society, and move toward comparative case studies and randomized clinical trial so that traditional herbal medicine is positioned as Evidence-based medicine.

• Archives of Pharmacal Research
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• v.19 no.2
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• pp.122-125
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• 1996

We examined the effect of topical application of Shimotsu-to, a traditional Chinese herbal prescription, on carrageenin-induced edema in rats and ultraviolet radiation-induced erythema in guinea pigs. Shimotsu-to (5% in water) markedly suppressed an acute edema of rat hindpaw induced by 1% carrageenin, and was more effective than any other single crude drug componcent of Shimotsu-to, Topical treatment with this prescription also inhibited ultraviolet erythema on the back skin of guinea pigs (a human sunbrun model). These results suggest the therapeutic effect on acute inflammation by topical application of Shimotsu-to.

• Journal of Pharmacopuncture
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• v.22 no.4
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• pp.260-268
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• 2019

Objectives: The Clinical Decision Support System (CDSS), which analyzes and uses electronic health records (EHR) for medical care, pursues patient-centered medical care. It is necessary to establish the CDSS in Korean medical services for objectification and standardization. For this purpose, analyses were performed on the points to be followed for CDSS implementation with a focus on herbal medicine prescription. Methods: To establish the CDSS in the prescription of Traditional Korean Medicine, the current prescription practices of Traditional Korean Medicine doctors were analyzed. We also analyzed whether the prescription support function of the electronic chart was implemented. A questionnaire survey was conducted querying Traditional Korean Medicine doctors working at Traditional Korean Medicine clinics and hospitals, to investigate their desired CDSS functions, and their perceived effects on herbal medicine prescription. The implementation of the CDSS among the audit software developers used by the Korean medical doctors was examined. Results: On average, 41.2% of Traditional Korean Medicine doctors working in Traditional Korean Medicine clinics manipulated 1 to 4 herbs, and 31.2% adjusted 4 to 7 herbs. On average, 52.5% of Traditional Korean Medicine doctors working in Traditional Korean Medicine hospitals adjusted 1 to 4 herbs, and 35.5% adjusted 4 to 7 herbs. Questioning the desired prescription support function in the electronic medical record system, the Traditional Korean Medicine doctors working at Korean medicine clinics desired information on 'medicine name, meridian entry, flavor of medicinals, nature of medicinals, efficacy,' 'herb combination information' and 'search engine by efficacy of prescription.' The doctors also desired compounding contraindications (eighteen antagonisms, nineteen incompatibilities) and other contraindicatory prescriptions, 'medicine information' and 'prescription analysis information through basic constitution analyses.' The implementation of prescription support function varied by clinics and hospitals. Conclusion: In order to implement and utilize the CDSS in a medical service, clinical information must be generated and managed in a standardized form. For this purpose, standardization of terminology, coding of prescriptions using a combination of herbal medicines, and unification such as the preparation method and the weights and measures should be integrated.

• The Journal of Korean Medicine
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• v.40 no.4
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• pp.29-40
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• 2019

Objectives: To analyze the prescription frequency of various herbs as either individual or major herbs (in terms of dosage) and their usage patterns in the treatment of different diseases for standardization of traditional Korean medicine. Methods: We analyzed the prescription database of patients at the Pusan National University Korean Medicine Hospital from the date of establishment of the hospital to February 2013. The complete prescription data were extracted from the electronic medical records of patients, and the prescription frequencies of individual herbs, particularly, of major herbs, were analyzed in terms of gender, age, and international classification of diseases (ICD) code. Results: The prescription frequency of individual herbs based on age and gender showed a similar pattern. Herbal mixtures were also distributed in a similar manner. The use of some herbs differed according to age and gender (Table 1.). The herbs that were used at high frequencies for a given ICD code had similar usage patterns in different categories. However, some major herbs in the "Jun (King)" category were used uniquely for a given ICD code (Table 2.). There was significant difference between male and female on ICD code E and N, but the other ICD codes had small differences. The ratio of herbal medicine by gender showed different usage patterns in each gender. Conclusions: The findings of our study provide fundamental data that reflect the real clinical conditions in South Korea, and therefore, can contribute to the standardization of TKM.

• Journal of Korean Medical classics
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• v.22 no.2
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• pp.305-313
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• 2009

With the recent increase of social demand of knowledge on traditional medicine, the construction of database is becoming a pressing matter. The reality is that while the social desire to adapt the high quality knowledge is growing fast, the field of Oriental Medicine has yet to organize its system. The number of Oriental Medical Doctors are limited, and there is no structured means of communication to expand the professional knowledge of these specialists to the public. Accordingly, an effective and structured knowledge system is in great need. In the process of building an Oriental Medicine database, prescription[方劑] and medicines[本草] are first in line. Consequently, we have taken the first step by organizing various methods to build the database containing information such as the formula, ingredients, composition, handling methods of herbal medicine written in traditional medical publications and herbal texts before the Song(宋) dynasty.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.1
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• pp.107-116
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• 2013

Objectives : This study was aimed to facilitate mutual comprehension between Western and Traditional Korean Medicine (TKM) by analyzing recognition of medical school students on traditional medical prescription and treatment such as herbal medicines and acupuncture. Methods : We conducted a survey targeting medical school students of four medical schools from April through May 2009, and analyzed 208 cases responded. Results : Survey results revealed that medical school students took knowledge of traditional medicine from TV programs and on the Web in general. They thought they had considerable traditional medical knowledge but did not almost understand for professional contents. Regardless of some positive recognition for traditional herbal medicine, negative perspectives were more common and its safety and efficacy on the drug reference were considered as a major reason. On the other hand, recognition on acupuncture was comparatively positive. Scientific data for both herbal medicine and acupuncture are lacking in reality but the attitude only for acupuncture was different. Of the survey respondents, 57.8% had negative attitude against diagnostic methods of TKM and 59.1% opposed to the usage of modern medical equipments by TKM doctors. With regard to the future position of TKM, they tacitly approved that TKM would be absorbed into the complementary and alternative medicine (CAM) and importance of TKM objectification, followed by Government's support. Conclusions : Medical school students neither affirm nor deny TKM as a whole but the state of awareness for each item was similar to the physician. In terms of TKM its internal and external innovation would be required to continuously establish objectification of TKM prescription and scientific research on treatment technology.

• Journal of Korean Medical classics
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• v.31 no.4
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• pp.69-78
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• 2018

Objectives : The aim of this study was to diversify the interpretation of formulas used for insomnia treatment by searching and analyzing herbal combinations in formulas used for insomnia treatment in Korean medicine. Methods : Frequency analysis was conducted on herbal combinations of 255 formulas related with insomnia, along with network analysis using Netminer 4.2.1. Results : This study has found herbal combinations used frequently in Korean medicine formulas used for insomnia treatment, and a result of network analysis composed of four communities. Each community consisted of herbs in affiliation of Yookmijihwangtang(六味地黃湯) and Samultang(四物湯), Bohyulchunghwatang(補血淸火湯) and Ondamtang(溫膽湯), Jungjihwan(定志丸) and Sanjointang(酸棗仁湯). Conclusions : This study could help in assisting researchers to diversify formula analysis in future studies. Moreover, the herbal combination in insomnia formulas could be used to search for insomnia formulas in other databases or creating a new prescription.

• Herbal Formula Science
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• v.24 no.4
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• pp.367-376
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• 2016

Objectives : The purpose of this study was to investigate the interpretation of the Gwibi-tang(歸脾湯, GBT) prescription in order to obtain the traditional significance. Methods : We have analyzed the interpretation on the GBT prescription through translations and comparisons based on classic books about the oriental medical prescriptions. Results : 1. The source of GBT in Dongeuibogam(東醫寶鑑) is Guchiryuyo(口齒類要), Jeongcheryuyo(正體類要) and Gyojubuinyangbang(校註婦人良方) etc. 2. Meaning of "GwiBi(歸脾)" in the GBT name is returning to the Bi(脾) which is origin of generating Gi(氣) and Blood(血). 3. GBT is composed of Sagunja-tang(四君子湯), Hwanggi-tang(黃芪湯) and Danggwibohyeol-tang(當歸補血湯) etc. 4. According to wide range of symptom, GBT can be varied by adding or subtracting herbs. Conclusions : In this study, we have demonstrated various methodologies. This paper will be useful to the future researchers and clinicians to conduct a study on herbal medicines such as the GBT.

• The Journal of Korean Medicine
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• v.26 no.2 s.62
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• pp.195-200
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• 2005

Objecitves: Peel of Citrus unshiu (Rutaceae) has been used in traditional herbal prescriptions. Hesperidin and naringin contents of Citri Unshii Pericarpium were determined and compared to herbal prescriptions. Then, the different extractions from prescriptions are explained with traditional herbal theories. Methods: The herb and herbal prescriptions were extracted in boiled water. A quantitative analysis was made of hesperidin and naringin using HPLC with-reversed-phase CIS column and a UV detector at 204nm. Elution was carried out at 1.0ml/min with $38\%$ methanol. Results and Conclusions: The extract of Citri Unshii Pericarpium for 180 min was the better method for extracting naringin and hesperidin. The flavonoid contents in remedies are different among several traditional herbal prescriptions. The reason for the difference can be explained with traditional drug interaction theories.