DOI QR코드

DOI QR Code

Analysis of prescription frequency of herbs in traditional Korean medicine hospital using electronic medical records

  • Lee, Byung-Wook (Department of Medical Classics and History, College of Korean Medicine, Dongguk University) ;
  • Cho, Hyun-Woo (Department of Korean Medical Science, School of Korean Medicine, Pusan National University) ;
  • Hwang, Eui-Hyoung (3rd Division of Clinical Medicine, School of Korean Medicine, Pusan National University) ;
  • Heo, In (3rd Division of Clinical Medicine, School of Korean Medicine, Pusan National University) ;
  • Shin, Byung-Cheul (3rd Division of Clinical Medicine, School of Korean Medicine, Pusan National University) ;
  • Hwang, Man-Suk (3rd Division of Clinical Medicine, School of Korean Medicine, Pusan National University)
  • Received : 2019.10.16
  • Accepted : 2019.11.21
  • Published : 2019.12.01

Abstract

Objectives: To analyze the prescription frequency of various herbs as either individual or major herbs (in terms of dosage) and their usage patterns in the treatment of different diseases for standardization of traditional Korean medicine. Methods: We analyzed the prescription database of patients at the Pusan National University Korean Medicine Hospital from the date of establishment of the hospital to February 2013. The complete prescription data were extracted from the electronic medical records of patients, and the prescription frequencies of individual herbs, particularly, of major herbs, were analyzed in terms of gender, age, and international classification of diseases (ICD) code. Results: The prescription frequency of individual herbs based on age and gender showed a similar pattern. Herbal mixtures were also distributed in a similar manner. The use of some herbs differed according to age and gender (Table 1.). The herbs that were used at high frequencies for a given ICD code had similar usage patterns in different categories. However, some major herbs in the "Jun (King)" category were used uniquely for a given ICD code (Table 2.). There was significant difference between male and female on ICD code E and N, but the other ICD codes had small differences. The ratio of herbal medicine by gender showed different usage patterns in each gender. Conclusions: The findings of our study provide fundamental data that reflect the real clinical conditions in South Korea, and therefore, can contribute to the standardization of TKM.

Keywords

References

  1. Sheng S, Wang J, Wang L, Liu H, Li P, Liu M, et al., Network pharmacology analyses of the antithrombotic pharmacological mechanism of Fufang Xueshuantong Capsule with experimental support using disseminated intravascular coagulation rats. Journal of ethnopharmacology, 2014;154:735-44. https://doi.org/10.1016/j.jep.2014.04.048
  2. Choi S, Chang I, A milestone in codifying the wisdom of traditional oriental medicine: TCM, Kampo, TKM, TVM-WHO international standard terminologies on traditional medicine in the western pacific region. Evid Based Complement Alternat Med, 2010;7(3):303-5. https://doi.org/10.1093/ecam/nen083
  3. Yoon CY, Kim HT, A study on Bang-Yak -Hap-Pyun. J Orient Med Class, 1991;5:151-349.
  4. Kang JH, Yang DH, Park YB, Kimp S, A Text Mining Approach to Find Patterns Associated with Diseases and Herbal Materials in Oriental Medicine. IJET, 2012;2(3):224-6.
  5. Kim HJ, Bae HS, Park SU, Moon SK, Park JM, Jung WS, Clinical Approach to the Standardization of Oriental Medical Diagnostic Pattern Identification in Stroke Patients. Evid Based Complement Alternat Med, 2011;2011:7.
  6. Lee B-W, Lee H-Y, Heo K-H, Cho H-W, Hwang M-S, Heo I, et al., Analysis of herbal medicine prescriptions for patients in an academic Korean medical hospital: A cross sectional study of electronic medical records (2010-2013). Chinese journal of integrative medicine, 2017.
  7. Jiang WY, Therapeutic wisdom in traditional Chinese medicine: a perspective from modern science. Trends Pharmacol Sci, 2005;26(11):558-63. https://doi.org/10.1016/j.tips.2005.09.006
  8. Yeh TS, Chuang HL, Huang WC, Chen YM, Huang CC, Hsu MC, Astragalus membranaceus improves exercise performance and ameliorates exercise-induced fatigue in trained mice. Molecules., 2014;19(3):2793-807. doi:10.3390/molecules19032793.
  9. Wang L, Zhou GB, Liu P, Song JH, Liang Y, Yan XJ, et al., Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proc Natl Acad Sci U.S.A., 2008;105(12):4826-31. https://doi.org/10.1073/pnas.0712365105
  10. Liu C, Tseng A, Yang S, Chinese herbal medicine: Modern applications of traditional formulas. CRC Press. 2004.
  11. Rhee I, Effect of Liriopis Tuber extract on the decrease of blood glucose. Hyosung Bull. Pharm. Sci, 1997;2:49-56.
  12. Wenyue J, Yu Y, Yanyan L, Effects of some drugs for resolving phlegm on blood rheological property in rats. J Tradit Chin Med, 2002;3:038.
  13. Cheng TO, The international textbook of cardiology. Pergamon Press. 1986.
  14. Chen JX, Ji B, Lu ZL, Hu LS, Effects of Chai Hu (Radix Burpleuri) containing formulation on plasma ${\beta}$-endorphin, epinephrine and dopamine in patients. Am J Chin Med, 2005;33(05):737-45. https://doi.org/10.1142/S0192415X05003296
  15. Hafez DA, Effect of extracts of ginger goots and cinnamon bark on fertility of male diabetic rats. J Am Sci, 2010;6:940-7.
  16. Choi BT, Seo IB, Lee DN, Kim HJ, Inhibiting Effecposets of Gungguijohyeoleum on the Development of Experimentally -induced Endometriosis in the Rats. J Orient Obstet Gynecol, 2008;21(3):34-59.