• Journal of Acupuncture Research
• /
• 제39권2호
• /
• pp.139-144
• /
• 2022

Peripheral facial nerve palsy is a neurological condition/disease characterized by unilateral paralysis of the facial muscles. We report the effects of complex Korean medicine treatment in 2 patients diagnosed with Bell's palsy who developed symptoms 3-4 days following vaccination with ChAdOx1 nCoV-19 and who received oral steroids and antiviral medications. Complex Korean medicine treatments including acupuncture, electroacupuncture, bee venom acupuncture, cupping therapy, herbal medicine, and physical therapy were performed. Symptom improvement was evaluated daily using the Numerical Rating Scale, House-Brackmann Grade, and Yanagihara's Score. Patient 1 was hospitalized for 22 days and Patient 2 visited the outpatient clinic 20 times. In both cases, postauricular pain caused by Bell's palsy disappeared, and symptoms of facial paralysis improved following completion of treatment. These findings could suggest that combined Korean medicine treatment may improve symptoms of peripheral facial nerve palsy.

• Journal of Acupuncture Research
• /
• 제35권4호
• /
• pp.187-192
• /
• 2018

Background: The aim of this study was to compare the effects of different cupping therapy methods combined with Korean medicine treatments for peripheral facial paralysis. Methods: 105 patients treated for peripheral facial paralysis with cupping therapy and other Korean medicine treatment at Gil Korean medicine hospital, Gachon University between May 19, 2014 and June 30, 2018 were selected and their medical charts retrospectively analyzed. 48 patients who met the inclusion criteria were divided into 2 groups: wet cupping (WC) therapy, or dry cupping (DC) therapy combined with Korean medicine treatment. The duration of treatment ranged from 2 weeks for inpatient treatment to 2 months for outpatient treatment. Both WC and DC therapy were performed on TE13, 3 times per week during the treatment period. The effect of cupping therapy was evaluated by using the Gross Grading System of the House-Brackmann (HB score) and the Yanagihara's Unweighted Grading System (Y score). Results: For both WC and DC treatment of symptoms related to peripheral facial paralysis, HB scores showed a significant decrease and Y scores showed a significant increase from baseline to end of treatment, indicating a beneficial improvement in patient symptoms for both WC and DC. Conclusion: In this study, both DC and WC treatment had significant improvements on peripheral facial paralysis symptoms, with WC having significantly greater beneficial effects than DC.

• Journal of Acupuncture Research
• /
• 제32권4호
• /
• pp.177-186
• /
• 2015

Objectives : This study was performed to analyze treatment outcomes of idiopathic and secondary frozen shoulder patients with clinical characteristics, as well as percentage of pain reduction, and to find out relevant factors for pain reduction in the frozen shoulders of each patient group. Methods : Data were collected from outpatients who visited the Acupuncture and Moxibustion department and treated with traditional Korean Medical treatments at a Korean Medicine Hospital from June 12, 2006 to June 30, 2015. Patients were divided into two groups; idiopathic and secondary frozen shoulder, based on imaging and medical records. Clinical characteristics (demographic characteristics, disease characteristics, treatment characteristics) and percentage pain reduction were collected. Percentage pain reduction was compared between two groups and relevant factors for pain reduction were analyzed. Results : 78 outpatients'medical records were reviewed. There was no significant difference of clinical characteristics between idiopathic and secondary frozen shoulder patients. In percentage pain reduction, there was no significant difference between the two groups. In the idiopathic frozen shoulder group, patients who had a short duration from the onset had a tendency for less pain (p<0.05). In the secondary frozen shoulder group, patients taking herbal medicine experienced significantly less pain (p<0.05). Conclusions : We could find no significant difference in percentage pain reduction with traditional Korean medicine between idiopathic and secondary frozen shoulder. Duration from the onset could be relevant in percentage pain reduction in idiopathic frozen shoulder, and taking herbal medicine could be relevant in the percentage pain reduction in secondary frozen shoulder.

• BMB Reports
• /
• 제55권9호
• /
• pp.417-428
• /
• 2022

Herbal medicine, a multi-component treatment, has been extensively practiced for treating various symptoms and diseases. However, its molecular mechanism of action on the human body is unknown, which impedes the development and application of herbal medicine. To address this, recent studies are increasingly adopting systems pharmacology, which interprets pharmacological effects of drugs from consequences of the interaction networks that drugs might have. Most conventional network-based approaches collect associations of herb-compound, compound-target, and target-disease from individual databases, respectively, and construct an integrated network of herb-compound-target-disease to study the complex mechanisms underlying herbal treatment. More recently, rapid advances in high-throughput omics technology have led numerous studies to exploring gene expression profiles induced by herbal treatments to elicit information on direct associations between herbs and genes at the genome-wide scale. In this review, we summarize key databases and computational methods utilized in systems pharmacology for studying herbal medicine. We also highlight recent studies that identify modes of action or novel indications of herbal medicine by harnessing drug-induced transcriptome data.

• 한방재활의학과학회지
• /
• 제33권4호
• /
• pp.145-156
• /
• 2023

Objectives The purpose of this review is to analyze trends of domestic research in Korean medicine treatment for frozen shoulder. Methods Among the clinical papers published from January 1, 2000 to August 2023, papers that treated frozen shoulders with Korean medicine treatment were searched through five domestic databases (Oriental Medicine Advanced Searching Integrated System, KMbase, Research Information Sharing Service, Science ON, Korean studies Information Service System). Results Finally, 12 studies were included. Three studies were clinical trials and 9 were observational studies. The most commonly used treatment was acupuncture. Range of movement (range of motion) and visual analogue scale were frequently used as measurement methods. Studies with significant effects were 66.6% in controlled trials and 100% in studies without control group. Conclusions In this study, literature on Korean medicine treatment for frozen shoulder was reviewed. As a result of the review, Korean medicine treatment for frozen shoulder showed significant results. However, there have been several limitations and suggest that more research and higher levels of research on Korean medicine treatment of frozen shoulder need to be conducted.

• 대한한방부인과학회지
• /
• 제33권1호
• /
• pp.86-103
• /
• 2020

Objectives: The purpose of this study is to analyse the domestic trends of Traditional Korean Medicine on Hot flush in menopausal women. Methods: We searched six databases and selected relevant papers according to the criteria. Results: 12 papers included case report, literature review, randomized controlled clinical trials (RCTs), Non-RCTs, and retrospective chart analysis study design. 1. The daily diary, Kupperman's Index, Menopause Rating Scale, Menopause-specific Quality of Life Questionnaire, Digital Infrared Thermographic Imaging were used as a measure of the symptoms of hot flush. 2. There were significant correlations between Thermographic images, Pulse energy, Lifestyle Habits, Low frequency power/High frequency power (LF/HF) ratio and certain items of Menopausal Symptoms Measurement. 3. The case report using Er-Xian decoction and Hwangryunhaedoktang-Gamibang showed significant effect. 4. Domestic RCT studies using herbal or acupuncture treatments showed a significant value of 3.4 on average in the quality assessment conducted in the study. However, the number of domestic studies included was five, which is not enough compared to foreign countries. Conclusions: This study examined domestic research trends on hot flushes of menopausal women and found that various evaluation tools and diagnostic methods were applied. It is necessary to conduct various RCT studies in Korea, where the number of studies is insufficient compared to overseas.

• 대한두개안면성형외과학회지
• /
• 제12권1호
• /
• pp.1-5
• /
• 2011

Purpose: The management of frontal sinus fractures and frontal sinus outflow tract (=FSOT) injuries is controversial. Traditional treatments include frontal sinus obliteration with a variety of material grafts, which all employ complicated algorithms for treatment planning. A simplified algorithm aiming for frontal sinus ventilation, however, can be achieved through the advanced technology of image guided endoscopic surgery and instruments. The authors explain this simplified treatment algorithm of frontal sinus fractures. Methods: The authors reviewed articles on the management of frontal sinus fractures. Results: Complicated treatment planning algorithms of frontal sinus fractures aiming for obliteration were replaced with a simplified algorithm aiming for ventilation of the frontal sinus. Conclusion: The authors suggest that a simplified algorithm can replace the complicated algorithms in selective cases.

• 대한한방내과학회지
• /
• 제44권4호
• /
• pp.814-822
• /
• 2023

Objective: This case report details the successful management of bowel perforation through traditional Korean medicine. Often, emergency surgery is required due to potential complications, such as peritonitis. In this case, the patient had previously undergone a total colectomy, making surgical treatment complicated. Methods: The patient revealed persistent abdominal pain and over 20 instances of diarrhea per day. During the course of treatment, which included two hospitalizations and one outpatient visit, acupuncture treatment and herbal medicine were administered. Throughout the treatment period, the intensity of abdominal pain and the frequency of diarrhea gradually decreased. Results: At the end of treatment, a follow-up abdominal computed tomography (CT) scan showed no evidence of perforation. Additionally, blood tests revealed no abnormalities in liver or kidney function, confirming the safety of the treatments.

• 대한약침학회지
• /
• 제25권3호
• /
• pp.149-185
• /
• 2022

Objectives: The Barak Valley is well known for its rich diversity of medicinal plants. Ethnomedicinal practices are prominent among Barak Valley's major and minor ethnic groups. This systemic review focuses on traditionally used medicinal plants found in the Barak Valley as reported in different ethnobotanical surveys. Methods: We searched various databases, including PubMed, Web of Science, and Google Scholar, to find ethnomedicinal surveys conducted in the Barak Valley. The search was performed using different terms, including ethnomedicinal survey, folk medicine, indigenous knowledge, and Barak Valley. Potential articles were identified following the exclusion and inclusion criteria. Results: A total of eight ethnobotanical surveys were included in this study. We identified a total of 216 plant species belonging to 167 genera and 87 families, which are widely used by the ethnic communities who live in the rural areas of Barak Valley for the treatment of various diseases and ailments. Conclusion: Folk medicine is the result of decades of accumulated knowledge and practices by people who live in rural communities based on their needs and provides an important source of information to assist the search for new pharmaceuticals. Therefore, available information on traditional medicinal plants needs to be explored scientifically to find effective and alternative treatments for different diseases.

• 동의신경정신과학회지
• /
• 제33권1호
• /
• pp.79-111
• /
• 2022

Major depressive disorder (MDD) causes a persistent feeling of sadness and loss of interest. It can lead to emotional and physical problems. Treatments such as antidepressant and cognitive behavioral therapy for MDD have many limitations. Traditional East Asian Herbal Medicine (TEAM) is a representative modality of Complementary and Integrative Medicine (CIM) which can be used for MDD. However, no study has systematically reviewed the efficacy or safety of TEAM for MDD so far. Therefore, we performed a systematic review and meta-analysis to evaluate effectiveness and safety of TEAM as a monotherapy for MDD. We only included TEAM that could be used in context of clinical setting in Korean Medicine. Outcomes were the Hamilton Depression Rating Scale (HAMD) and total effective rate (TER). After comprehensive electronic search of 11 databases, we included 28 randomized controlled trials (RCTs) that compared HM as monotherapy with antidepressant for MDD. Meta-analysis showed that TEAM had significant benefits in reducing HAMD (MD=-0.40, 95% CI: -0.67 to -0.13, p=0.003, I²=85%) and improving TER (RR=1.06, 95% CI: 1.02 to 1.10, p=0.003, I²=0%). It also appeared to be safer than antidepressant in terms of adverse effects. Methods used for RCTs were poor and the quality of evidence was graded 'low' or 'moderate'. These findings indicate that the use of HM as a monotherapy might have potential benefits in MDD treatment as an alternative to antidepressant. However, considering the methodological quality of included RCTs, the clinical evidence is uncertain. Further well-designed RCTs are required to confirm these findings.